The entrance to the Kentucky Science Center with a large circular structure in the foreground.

West Main Historic District hotels in Louisville

  • Change your mind

    Book hotels with free cancellation
  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
  • Be picky

    Search almost a million properties worldwide

Check prices for these dates

Filter by

Guest rating
Guest rating
Star rating

Our top choices for West Main Historic District hotels

Embassy Suites Louisville Downtown

Embassy Suites Louisville Downtown
4.0 star property
West Main Historic District
9.0 out of 10, Wonderful, (1,300 reviews)
"We liked everything about our stay"
United States
Mark
The price is HK$1,022
HK$1,203 total
includes taxes & fees
31 Jul - 1 Aug
Embassy Suites Louisville Downtown

Holiday Inn Express & Suites Louisville Downtown by IHG

Holiday Inn Express & Suites Louisville Downtown by IHG
2.5 star property
West Main Historic District
8.8 out of 10, Excellent, (1,727 reviews)
"Wonderful location, very nice hotel with great amenities"
United States
Astrid
The price is HK$646
HK$760 total
includes taxes & fees
27 Jul - 28 Jul
Holiday Inn Express & Suites Louisville Downtown by IHG

Galt House Hotel Trademark Collection by Wyndham

Galt House Hotel Trademark Collection by Wyndham
4.0 star property
West Main Historic District
9.0 out of 10, Wonderful, (4,180 reviews)
"Great hotel & stay!"
United States
Jennifer
The price is HK$1,263
HK$1,486 total
includes taxes & fees
1 Aug - 2 Aug
Galt House Hotel Trademark Collection by Wyndham

Omni Louisville Hotel

Omni Louisville Hotel
4.0 star property
West Main Historic District
9.4 out of 10, Exceptional, (1,995 reviews)
"Beautiful, clean property with many things to do at and around the hotel."
United States
Brittany
The price is HK$1,248
HK$1,469 total
includes taxes & fees
2 Aug - 3 Aug
Omni Louisville Hotel

The Grady

The Grady
4.0 star property
West Main Historic District
9.4 out of 10, Exceptional, (1,000 reviews)
"Great place to stay!"
United States
Jennifer
The price is HK$1,390
HK$1,635 total
includes taxes & fees
9 Aug - 10 Aug
The Grady

Cambria Hotel Louisville Downtown-Whiskey Row

Cambria Hotel Louisville Downtown-Whiskey Row
3.0 star property
West Main Historic District
9.4 out of 10, Exceptional, (1,000 reviews)
The price is HK$868
HK$1,021 total
includes taxes & fees
16 Aug - 17 Aug
Cambria Hotel Louisville Downtown-Whiskey Row

Hotel Bourré Bonne Louisville, Curio Collection by Hilton

Hotel Bourré Bonne Louisville, Curio Collection by Hilton
4.0 star property
West Main Historic District
9.4 out of 10, Exceptional, (127 reviews)
"Great stay"
United States
Kristen
The price is HK$1,376
HK$1,619 total
includes taxes & fees
2 Aug - 3 Aug
Hotel Bourré Bonne Louisville, Curio Collection by Hilton

Towneplace Suites By Marriott Louisville Downtown

Towneplace Suites By Marriott Louisville Downtown
3.0 star property
West Main Historic District
9.2 out of 10, Wonderful, (676 reviews)
"Nice staff and clean room."
United States
Christina
The price is HK$862
HK$1,015 total
includes taxes & fees
5 Aug - 6 Aug
Towneplace Suites By Marriott Louisville Downtown

Fairfield Inn & Suites by Marriott Louisville Downtown

Fairfield Inn & Suites by Marriott Louisville Downtown
3.0 star property
West Main Historic District
8.4 out of 10, Very good, (1,000 reviews)
"Enjoyed our stay!"
United States
Mary
The price is HK$793
HK$933 total
includes taxes & fees
26 Jul - 27 Jul
Fairfield Inn & Suites by Marriott Louisville Downtown

Homewood Suites by Hilton Louisville Downtown, KY

Homewood Suites by Hilton Louisville Downtown, KY
3.0 star property
West Main Historic District
9.4 out of 10, Exceptional, (1,004 reviews)
"The location was great for what my family wanted to do, as well as the price and the breakfast was a nice plus."
United States
Naomy
The price is HK$932
HK$1,097 total
includes taxes & fees
6 Aug - 7 Aug
Homewood Suites by Hilton Louisville Downtown, KY

Econo Lodge Louisville Downtown

Econo Lodge Louisville Downtown
2.0 star property
West Main Historic District
7.0 out of 10, Good, (1,003 reviews)
"Great stay!"
United States
Shaina T.
The price is HK$501
HK$589 total
includes taxes & fees
16 Aug - 17 Aug
Econo Lodge Louisville Downtown

21c Museum Hotel Louisville

21c Museum Hotel Louisville
4.5 star property
West Main Historic District
9.4 out of 10, Exceptional, (1,002 reviews)
"Beautiful property, on-site restaurant was delicious. Beds very nice."
United States
nicolle
The price is HK$1,259
HK$1,521 total
includes taxes & fees
9 Aug - 10 Aug
21c Museum Hotel Louisville

Hyatt Regency Louisville

Hyatt Regency Louisville
4.0 star property
West Main Historic District
8.8 out of 10, Excellent, (1,002 reviews)
"Beautiful Hotel!"
United States
Joseph
The price is HK$1,168
HK$1,374 total
includes taxes & fees
1 Aug - 2 Aug
Hyatt Regency Louisville

Aloft by Marriott Louisville Downtown

Aloft by Marriott Louisville Downtown
3.0 star property
West Main Historic District
9.0 out of 10, Wonderful, (1,000 reviews)
"great location, clean and pleasant staff"
United States
Margarita
The price is HK$1,035
HK$1,217 total
includes taxes & fees
31 Jul - 1 Aug
Aloft by Marriott Louisville Downtown

Holiday Inn Louisville Downtown by IHG

Holiday Inn Louisville Downtown by IHG
3.0 star property
West Main Historic District
8.0 out of 10, Very good, (943 reviews)
"Very nice clean hotel, staff were very friendly as well. I highly recommend. I was satisfied with my stay."
United States
Ramla
The price is HK$490
HK$577 total
includes taxes & fees
3 Aug - 4 Aug
Holiday Inn Louisville Downtown by IHG

Hotel Distil, Autograph Collection

Hotel Distil, Autograph Collection
4.0 star property
West Main Historic District
9.6 out of 10, Exceptional, (483 reviews)
"Great hotel and great staff."
United States
Jasmine
The price is HK$1,580
HK$1,859 total
includes taxes & fees
2 Aug - 3 Aug
Hotel Distil, Autograph Collection

Hilton Garden Inn Louisville Downtown

Hilton Garden Inn Louisville Downtown
3.5 star property
West Main Historic District
8.4 out of 10, Very good, (1,005 reviews)
"Twas a great time, location was mazing"
United States
Porfirio
The price is HK$765
HK$900 total
includes taxes & fees
16 Aug - 17 Aug
Hilton Garden Inn Louisville Downtown

SpringHill Suites by Marriott Louisville Downtown

SpringHill Suites by Marriott Louisville Downtown
3.0 star property
West Main Historic District
8.4 out of 10, Very good, (1,001 reviews)
"Clean room, friendly staff, free breakfast, and pool/gym available. Convenient location. Enjoyed my stay!"
United States
Stephen
The price is HK$726
HK$855 total
includes taxes & fees
19 Jul - 20 Jul
SpringHill Suites by Marriott Louisville Downtown

Moxy Louisville Downtown

Moxy Louisville Downtown
3.5 star property
West Main Historic District
9.2 out of 10, Wonderful, (798 reviews)
"Great and fun spot! Enjoyed our one night here"
United States
Adam
The price is HK$1,011
HK$1,190 total
includes taxes & fees
2 Aug - 3 Aug
Moxy Louisville Downtown

Louisville Marriott Downtown

Louisville Marriott Downtown
4.0 star property
West Main Historic District
9.0 out of 10, Wonderful, (1,000 reviews)
"Great location and friendly staff. Loved their bar and lobby area."
United States
Bikash
The price is HK$1,315
HK$1,547 total
includes taxes & fees
16 Aug - 17 Aug
Louisville Marriott Downtown
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Compare popular hotels in West Main Historic District

Property
Property class
Guest rating
Breakfast included
Pool
Spa
Pet-friendly
WiFi included
Terrace/patio
Homewood Suites by Hilton Louisville Downtown, KY
3.0 star property
9.4
Exceptional
1,004 reviews
View
Dining
Cambria Hotel Louisville Downtown-Whiskey Row
3.0 star property
9.4
Exceptional
1,000 reviews
View
Terrace/patio
Hotel Distil, Autograph Collection
4.0 star property
9.6
Exceptional
483 reviews
View
Property amenity
Towneplace Suites By Marriott Louisville Downtown
3.0 star property
9.2
Wonderful
676 reviews
View
3 bars/lounges, cocktail bar, lobby lounge
Omni Louisville Hotel
4.0 star property
9.4
Exceptional
1,995 reviews
View

Where to stay in West Main Historic District

Find the best West Main Historic District areas for the activities you enjoy most.

Downtown Louisville

The cultural heart of the city beats with baseball, boxing and music, with sporting fields, live bands and a center for Muhammad Ali, the city’s most famous son.

St. Matthews

St. Matthews is noteworthy for its shopping, and you can make a stop at top attractions like Mall St. Matthews and Saint Matthews Pavilion Shopping Center.

Jeffersontown

Jeffersontown is known for its abundant dining options, and you can plan a trip to Jeffersontown Commons Shopping Center and Plainview Tennis Center while you're in town.

Old Louisville

Old Louisville is known for its ample dining options, and you can make a stop by Conrad-Caldwell House Museum and Ohio River Valley while in the area.

Fairgrounds

While visiting Fairgrounds, you might make a stop by sights like Kentucky Kingdom and Freedom Hall.

Top West Main Historic District Hotel Reviews

Frequently asked questions

What's it like in West Main Historic District?
Travellers love the West Main Historic District neighbourhood for its stunning river views, array of dining options and sporting events. Are you looking for West Main Historic District travel tips? Make sure that you visit Louisville Slugger Museum and Louisville Science Center while you're in the neighbourhood.
Where is the best hotel for a stay in West Main Historic District?
Based on our traveller data, Galt House Hotel Trademark Collection by Wyndham is one of the top choices for your stay in West Main Historic District. This hotel is a short 4-minute walk from KFC Yum Center, and it offers a full-service spa and 4 restaurants. Other good choices for your stay in the area include Omni Louisville Hotel and Holiday Inn Louisville Downtown by IHG.
How many hotels will I be able to find in the West Main Historic District area?
If you're searching for places to stay in Louisville, Expedia has something to meet your needs with 222 West Main Historic District hotels and other accommodation options to choose from.
If I need to cancel my hotel reservation in West Main Historic District, will I receive a refund?
Yes! You'll find that most hotel room reservations are fully refundable as long as you cancel before the accommodation's cancellation deadline, which often is within 24-48 hours of your scheduled arrival. If your reservation is non-refundable, you might be able to still cancel and get a refund within a 24-hour period of your booking. Enter your dates, click on "Search", then filter by "fully refundable" to view the best options available in West Main Historic District.
What is there to do around this Louisville neighbourhood?
For cultural attractions in West Main Historic District, head to Flame Run Glass Studio and Gallery, Frazier International History Museum and Louisville Slugger Museum. Louisville Science Center and 21c Museum Hotel are also a couple of places to visit in the neighbourhood. Kentucky Peerless Distilling Co., Louisville Glassworks and SAR Genealogical Research Library: NSSAR Library are just a few of the places to visit in and around West Main Historic District. While you're out sightseeing, Kentucky Museum of Art and Craft and Russell District Marker are a couple of additional sights to visit in Louisville.

Explore a world of travel with Expedia