Eastern Panama Holiday Rentals

  • Change your mind

    Book hotels with free cancellation
  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
  • Be picky

    Search almost a million properties worldwide

Check prices for these dates

In two weeks
In two months
In three months
In four months

Our top choices for Eastern Panama holiday rentals

San Blas Private Beach Cabin

San Blas Private Beach Cabin
2.5 star property
Narganá
San Blas Private Beach Cabin

Private Over-Water Cabins on San Blas Island

Private Over-Water Cabins on San Blas Island
2.5 star property
Narganá
The price is HK$1,630
HK$2,572 total
includes taxes & fees
29 Jan - 30 Jan
Private Over-Water Cabins on San Blas Island

San Blas Private Oceanfront Cabin

San Blas Private Oceanfront Cabin
2.5 star property
Narganá
The price is HK$2,020
HK$3,001 total
includes taxes & fees
29 Jan - 30 Jan
San Blas Private Oceanfront Cabin

San Blas Tour Aridub

San Blas Tour Aridub
2.0 star property
Narganá
The price is HK$667
HK$1,938 total
includes taxes & fees
29 Jan - 30 Jan
San Blas Tour Aridub

Caribbean getaway: beach cottage just on the sand

Caribbean getaway: beach cottage just on the sand
Palenque
10.0 out of 10, Exceptional, (1 review)
"The beach view was perfect! I loved hearing the waves all day and throughout the night. My dog and I enjoyed everything and felt very comfortable. "
United States
Beth N.
The price is HK$2,020
HK$2,472 total
includes taxes & fees
1 Feb - 2 Feb
Caribbean getaway: beach cottage just on the sand

Cabaña La Punta op het Strand!!

Cabaña La Punta op het Strand!!
Colón Province
The price is HK$1,014
HK$1,333 total
includes taxes & fees
29 Jan - 30 Jan
Cabaña La Punta op het Strand!!

Private Over-the-Water Cabin in San Blas including Meals

Private Over-the-Water Cabin in San Blas including Meals
2.5 star property
Mirladub
Private Over-the-Water Cabin in San Blas including Meals

Exclusive sailboat for 2 people all inclusive in San Blas islands

Exclusive sailboat for 2 people all inclusive in San Blas islands
Guna Yala
10.0 out of 10, Exceptional, (1 review)
"Anita e Federico sono state il valore aggiunto in queste isole meravigliose. La loro disponibilita, le loro attenzioni, i sorridenti contatti di Anita con la popolazione dei Guna e la cucina superlativa di Federico hanno reso speciale la nostra vacanza che ha soddisfatto appieno le nostre aspettative. Discreta e deliziosa la presenza della gattina (la principessa di bordo) Shanu. Grazie di tutto!"
United States
Grazia B.
The price is HK$4,133
HK$4,717 total
includes taxes & fees
11 Feb - 12 Feb
Exclusive sailboat for 2 people all inclusive in San Blas islands

All inclusive 4-bedroom Catamaran up to 8 people in San Blas Panama

All inclusive 4-bedroom Catamaran up to 8 people in San Blas Panama
Guna Yala Comarca
The price is HK$6,454
HK$7,639 total
includes taxes & fees
4 Feb - 5 Feb
All inclusive 4-bedroom Catamaran up to 8 people in San Blas Panama

Despierta sobre el mar

Despierta sobre el mar
Garrote
6.0 out of 10, (1 review)
The price is HK$585
HK$838 total
includes taxes & fees
29 Jan - 30 Jan
Despierta sobre el mar

Deluxe Beachfront 4-bedroom house in Colón Province

Deluxe Beachfront 4-bedroom house in Colón Province
Colón Province
The price is HK$2,643
HK$3,010 total
includes taxes & fees
29 Jan - 30 Jan
Deluxe Beachfront 4-bedroom house in Colón Province

Catamaran experience in paradise

Catamaran experience in paradise
Guna Yala Comarca
The price is HK$4,629
HK$9,518 total
includes taxes & fees
29 Jan - 30 Jan
Catamaran experience in paradise

Private cabin in San Blas

Private cabin in San Blas
Panama , Betania
The price is HK$2,066
HK$2,300 total
includes taxes & fees
29 Jan - 30 Jan
Private cabin in San Blas

San Blas Private Over-the-Water Cabin

San Blas Private Over-the-Water Cabin
2.5 star property
Narganá
8.0 out of 10, Very good, (2 reviews)
"I liked the modern payment system that was used for booking the trip, the food was great, the location was as described. I disliked the communication with the reseller this booking goes through. They dropped the ball on communicating pickup time and itinerary confirmation, even when i tried calling and emailing them. I also disliked the value of what you get with this trip. Id expect better cleanliness and standards for this trip. I also disliked when the staff on the island said i needed to pay...
United States
Andrew
San Blas Private Over-the-Water Cabin

Jacuzy, pool and lake at the same house.

Jacuzy, pool and lake at the same house.
Colon
10.0 out of 10, Exceptional, (1 review)
"Great. Please take care of the cat"
United States
KENNETH E.
The price is HK$267
HK$540 total
includes taxes & fees
29 Jan - 30 Jan
Jacuzy, pool and lake at the same house.

Charming cottage with 2 separate beds and a beautiful view of the river

Charming cottage with 2 separate beds and a beautiful view of the river
Santa Rosa
10.0 out of 10, Exceptional, (1 review)
"Wir fanden die Unterkunft aufgrund der guten Wegbeschreibung sofort. Die Empfang war sehr nett. Das Haus war sehr sehr sauber und wir haben uns sehr wohl gefühlt. Alles war perfekt. Es war die sauberste/beste Unterkunft die wir bei unserer Panama Rundtour in Panama hatte. Erik und Alba alles Gute und vielen Dank."
Germany
Birgit U.
The price is HK$982
HK$1,138 total
includes taxes & fees
29 Jan - 30 Jan
Charming cottage with 2 separate beds and a beautiful view of the river

Elegance and comfort in old town panama

Elegance and comfort in old town panama
Panamá
The price is HK$390
HK$702 total
includes taxes & fees
29 Jan - 30 Jan
Elegance and comfort in old town panama

Tranquil cabin with WiFi in Los Altos de Cerro Azul

Tranquil cabin with WiFi in Los Altos de Cerro Azul
Los Altos de Cerro Azul
The price is HK$1,170
HK$1,598 total
includes taxes & fees
29 Jan - 30 Jan
Tranquil cabin with WiFi in Los Altos de Cerro Azul

BEAUTIFUL APARTMENT IN FRONT OF THE SEA

BEAUTIFUL APARTMENT IN FRONT OF THE SEA
Portobelo
8.0 out of 10, Very good, (3 reviews)
"All of it! Gabriel is a marvelous host; absolutely above and beyond. The house is lovely, very unique, and the location, right on the water, superb. We'll be back!"
United States
Rosa M.
The price is HK$1,222
HK$1,378 total
includes taxes & fees
29 Jan - 30 Jan
BEAUTIFUL APARTMENT IN FRONT OF THE SEA

Bala Bliss Charming 2-bedroom apartment with WiFi, AC in Maria Chiquita

Bala Bliss Charming 2-bedroom apartment with WiFi, AC in Maria Chiquita
Maria Chiquita
6.8 out of 10, (3 reviews)
"Well-appointed apartment, view of the ocean, big pool, fast Internet, attentive security. We had a great time here, thanks!"
United States
Will
The price is HK$702
HK$1,131 total
includes taxes & fees
29 Jan - 30 Jan
Bala Bliss Charming 2-bedroom apartment with WiFi, AC in Maria Chiquita
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Save an average of 15% on thousands of hotels when you're signed in

Top Eastern Panama Hotel Reviews

Find out more about Eastern Panama

Search for holiday rentals in Eastern Panama on Expedia! You can easily find your home rentals, villas, holiday apartments in Eastern Panama using one of the methods below:

  • View our selection of featured holiday rentals in Eastern Panama
  • Use the map to find apartments and other holiday homes in the Eastern Panama neighbourhood you prefer
  • Enter your travel dates to view the best deals on holiday rentals in Eastern Panama while they last

Look no further and take a look at our great range of rental properties in Eastern Panama!