Independence Square
Visit Independence Square
Tours & day trips
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City Sightseeing Panama City Hop-On Hop-Off Bus Tour
Private & custom tours
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Jungle quad bike Waterfall and Zipline Adventure from Panama City
Cruises & boat tours
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All-inclusive Sunset Panama Bay Catamaran Tour From Panama City
Classes & workshops
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Learn about Panama cocoa and create your own chocolate bar
Air, helicopter & balloon tours
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Charter Flights Panama City
Popular places to visit
Metropolitan Cathedral of Panama
Learn about the local history of Panama City with a stop at Metropolitan Cathedral of Panama. Visit the shops and top-notch restaurants in this vibrant area.
National Institute of Culture
You can study the exhibits at National Institute of Culture, a museum with a storied past, during your holiday in Panama City. Visit the shops and top-notch restaurants in this vibrant area.
Museum of History Panama
You can browse the exhibits at Museum of History Panama, a museum with a story of its own, during your trip to Panama City. Visit the shops and top-notch restaurants in this vibrant area.
Interoceanic Canal Museum
You can study the exhibits at Interoceanic Canal Museum, a museum with a storied past, during your trip to Panama City. Visit the shops and top-notch restaurants in this vibrant area.
Museo de la Esmeralda
You can spend time exploring the galleries in Museo de la Esmeralda during your travels in Panama City. You can enjoy the bars while in the area.
Mola Museum
You can spend time exploring the galleries in Mola Museum in Panama City. You can enjoy the bars while in the area.
Top Independence Square Hotel Deals
Hotel Riu Plaza Panama
Sofitel Legend Casco Viejo, Panama City
Central Hotel Panama Casco Viejo
Hotel San Felipe
American Trade Hotel
Magnolia Inn
Hotel Casa Panamá
Casa Contemporanea by Wynwood House
Casa Mallet by Wynwood House
Explore a world of travel with Expedia
Explore a world of travel with Expedia
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