O Brien hotels from HK$338

  • Change your mind

    Book hotels with free cancellation
  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
  • Be picky

    Search almost a million properties worldwide

Check prices for these dates

Filter by

Guest rating
Guest rating
Star rating

Our top choices for O Brien hotels

Motel 6 – Lake City, Fl – Medical Center

Motel 6 – Lake City, Fl – Medical Center
2.0 star property
Lake City
8.2 out of 10, Very good, (107 reviews)
  • cleanliness
    Modern Lake City motel near medical centre with free WiFi and parking.
"Dog friendly and price."
United States
John
The price is HK$471
HK$530 total
includes taxes & fees
1 Mar - 2 Mar
Motel 6 – Lake City, Fl – Medical Center

Econo Lodge Live Oak

Econo Lodge Live Oak
2.0 star property
Live Oak
7.0 out of 10, Good, (282 reviews)
  • cleanliness
    Enjoy a restful stay at this Live Oak motel with free breakfast and outdoor pool.
"Clean room with plenty of towels and soaps. "
United States
Melissa
The price is HK$511
HK$563 total
includes taxes & fees
10 Mar - 11 Mar
Econo Lodge Live Oak

Quality Inn & Suites Live Oak I-10 Exit 283

Quality Inn & Suites Live Oak I-10 Exit 283
2.5 star property
Live Oak
7.0 out of 10, Good, (526 reviews)
  • cleanliness
    Discover a peaceful retreat near I-10 with a welcoming outdoor pool and restaurant.
"Clean spacious rooms, friendly staff, convenient location "
United States
Jerry
The price is HK$721
HK$793 total
includes taxes & fees
12 Mar - 13 Mar
Quality Inn & Suites Live Oak I-10 Exit 283

Quality Inn White Springs Suwanee

Quality Inn White Springs Suwanee
2.5 star property
Live Oak
7.2 out of 10, Good, (634 reviews)
  • cleanliness
    Wake up to the Suwanee River nearby with free hot breakfast and outdoor pool access.
"Friendly staff, clean though older decor, great value for the price "
United States
Vince
The price is HK$531
HK$584 total
includes taxes & fees
22 Feb - 23 Feb
Quality Inn White Springs Suwanee

High Springs Country Inn

High Springs Country Inn
2.0 star property
High Springs
8.4 out of 10, Very good, (20 reviews)
  • cleanliness
    Serene country motel in High Springs with easy access to local attractions.
"Great remodel of a retro motel."
United States
Kathleen
The price is HK$462
HK$520 total
includes taxes & fees
12 Feb - 13 Feb
High Springs Country Inn

Holiday Inn Express & Suites Live Oak by IHG

Holiday Inn Express & Suites Live Oak by IHG
2.5 star property
Live Oak
8.4 out of 10, Very good, (795 reviews)
  • cleanliness
    Enjoy comfort in Live Oak with a restaurant and fitness centre on site.
"The room was clean. Bed was comfortable. Staff very nice. Breakfast was delicious. Great experience "
United States
Frank
The price is HK$942
HK$1,037 total
includes taxes & fees
22 Feb - 23 Feb
Holiday Inn Express & Suites Live Oak by IHG

BlueGem Motel

BlueGem Motel
2.0 star property
High Springs
9.2 out of 10, Wonderful, (405 reviews)
  • cleanliness
    Cosy High Springs motel with comfortable beds near local attractions and parks.
"Beautiful room, very clean and the bed was incredibly soft and comfortable to sleep in! "
United States
Julians
The price is HK$649
HK$731 total
includes taxes & fees
20 Feb - 21 Feb
BlueGem Motel

Postcard Cabins Gilchrist Springs, Outdoor Collection by Marriott Bonvoy

Postcard Cabins Gilchrist Springs, Outdoor Collection by Marriott Bonvoy
2.0 star property
High Springs
10.0 out of 10, Exceptional, (174 reviews)
  • cleanliness
    Waterfront cabin retreat with kitchenettes and patios near Gilchrist Spring.
"We had such a great time, the cabin was nice and clean and had everything you might need. We loved the little detail of the handwritten postcard and map! The fireplace area was so nice too, perfect for a little getaway! "
United States
Ellie
The price is HK$930
HK$1,710 total
includes taxes & fees
10 Feb - 11 Feb
Postcard Cabins Gilchrist Springs, Outdoor Collection by Marriott Bonvoy

Royal Inn

Royal Inn
2.0 star property
Alachua
7.2 out of 10, Good, (192 reviews)
  • cleanliness
    Affordable lodging near sports complex with free WiFi and parking for travellers.
"Good value and close to highway. "
United States
Ross
The price is HK$506
HK$570 total
includes taxes & fees
10 Feb - 11 Feb
Royal Inn

Hampton Inn & Suites Alachua I-75

Hampton Inn & Suites Alachua I-75
2.5 star property
Alachua
9.4 out of 10, Exceptional, (484 reviews)
  • cleanliness
    Enjoy comfortable stays near Alachua Sports Complex with pool and fitness access.
"We visited family in the area and stayed here, hotel was clean, quiet, staff was great and room was so comfortable and spacious for our family of 5. Will definitely stay again!"
United States
Libbi
The price is HK$814
HK$915 total
includes taxes & fees
22 Feb - 23 Feb
Hampton Inn & Suites Alachua I-75

Americas Best Value Inn Alachua

Americas Best Value Inn Alachua
2.0 star property
Alachua
4.8 out of 10, (605 reviews)
  • cleanliness
    Great value motel in Alachua with outdoor pool and complimentary WiFi access.
"Nicer than a Marriott. "
United States
Dan
The price is HK$420
HK$473 total
includes taxes & fees
10 Feb - 11 Feb
Americas Best Value Inn Alachua

Cindys Motel

Cindys Motel
2.5 star property
Mayo
8.8 out of 10, Excellent, (129 reviews)
  • cleanliness
    Enjoy the quiet comfort of this well-maintained motel in Mayo with free parking.
"Easy parking next to your door and easy check in.beds are comfy and as a single parent traveler i felt safe"
United States
Diane
Cindys Motel

Suwannee River Rendezvous

Suwannee River Rendezvous
2.5 star property
Mayo
8.8 out of 10, Excellent, (23 reviews)
  • cleanliness
    Serene riverside resort with 3 outdoor pools for a refreshing Florida retreat.
"Awesome place to stay, beautiful location and great accommodations. Friendly staff and lots to do!"
United States
Lauren
The price is HK$211
HK$338 total
includes taxes & fees
10 Feb - 11 Feb
Suwannee River Rendezvous

Palms Garden Inn

Palms Garden Inn
2.0 star property
Lake City
7.4 out of 10, Good, (584 reviews)
  • cleanliness
    Quiet motel with comfortable beds near Lake City's attractions and state parks.
"Clean and nice staff "
United States
apollo
The price is HK$500
HK$563 total
includes taxes & fees
21 Feb - 22 Feb
Palms Garden Inn

Holiday Inn & Suites Lake City by IHG

Holiday Inn & Suites Lake City by IHG
3.0 star property
Lake City
8.6 out of 10, Excellent, (1,001 reviews)
  • cleanliness
    Lakefront getaway with indoor pool, dining, and fitness options near city attractions.
"Great place"
United States
John
The price is HK$727
HK$818 total
includes taxes & fees
15 Feb - 16 Feb
Holiday Inn & Suites Lake City by IHG

Holiday Inn Express & Suites Alachua - Gainesville Area by IHG

Holiday Inn Express & Suites Alachua - Gainesville Area by IHG
3.5 star property
Alachua
9.4 out of 10, Exceptional, (1,003 reviews)
  • cleanliness
    Relaxing retreat near Gainesville with pool, hot tub, and free breakfast.
"Staff and hotel were wonderful!"
United States
Sandra
The price is HK$844
HK$949 total
includes taxes & fees
22 Feb - 23 Feb
Holiday Inn Express & Suites Alachua - Gainesville Area by IHG

Comfort Suites Lake City

Comfort Suites Lake City
2.5 star property
Lake City
9.6 out of 10, Exceptional, (1,002 reviews)
  • cleanliness
    Modern hotel near Lake City attractions with a welcoming outdoor pool.
"The staff is great"
United States
Tana
The price is HK$921
HK$1,036 total
includes taxes & fees
22 Feb - 23 Feb
Comfort Suites Lake City

Home2 Suites by Hilton Lake City

Home2 Suites by Hilton Lake City
3.0 star property
Lake City
9.4 out of 10, Exceptional, (760 reviews)
  • cleanliness
    Restful retreat in Lake City with outdoor pool and modern fitness centre.
"This is an excellent hotel while you roadtrip:)"
United States
Desiree Moreno
The price is HK$956
HK$1,076 total
includes taxes & fees
15 Feb - 16 Feb
Home2 Suites by Hilton Lake City

Fairfield Inn & Suites Lake City

Fairfield Inn & Suites Lake City
2.5 star property
Lake City
9.0 out of 10, Wonderful, (194 reviews)
  • cleanliness
    Relax and rejuvenate at this Lake City hotel with indoor pool and friendly staff.
"Friendly staff, convenient location, clean rooms, excellent breakfast"
United States
Keith
The price is HK$836
HK$941 total
includes taxes & fees
16 Feb - 17 Feb
Fairfield Inn & Suites Lake City

Courtyard By Marriott Lake City

Courtyard By Marriott Lake City
3.0 star property
Lake City
9.6 out of 10, Exceptional, (199 reviews)
  • cleanliness
    Visit Lake City with a tranquil pool and modern amenities at this business hotel.
"Nice and clean. Friendly staff."
United States
Jennifer
The price is HK$836
HK$941 total
includes taxes & fees
15 Feb - 16 Feb
Courtyard By Marriott Lake City
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Save an average of 15% on thousands of hotels when you're signed in

Learn more about O Brien

Escape to this rural Florida gem where the Suwannee River offers peaceful kayaking trips and fishing adventures. Nearby Spirit of the Suwannee Music Park hosts live concerts, while O'Brien's local farms welcome visitors for fresh produce and family-friendly activities.

kayakers at Rock Bluff Spring on the Suwanneee River, Gilchrist County, Florida

Top O Brien Hotel Reviews

More cheap stays in O Brien

Frequently asked questions

Where is the best place to stay in O Brien?
Holiday Inn Express & Suites Alachua - Gainesville Area by IHG, located 29.9 mi (48.2 km) from the heart of O Brien, is a top choice for your stay, based on our traveller data. Two other options for your trip to the area are La Quinta Inn & Suite by Wyndham Lake City and Postcard Cabins Gilchrist Springs, Outdoor Collection by Marriott Bonvoy. See all available top hotels, or vacation rentals in O Brien.
What are some of the best holiday rentals that O Brien has to offer?
Royal Springs Riverfront Retreat on 3 acres, kayak/canoe, boat ramp, huge decks!: This highly rated holiday home rental in O Brien is located on the beach, and has a balcony, a garden and a BBQ to put you at ease in your new surroundings. It has 3 bedrooms, as well as a kitchen with a dishwasher, a fridge and a stovetop, so that you can cook with friends or family. You and your friends and family can relax into your holiday with amenities such as a selection of games. See all vacation rentals in O Brien.
If I need to cancel my hotel reservation in O Brien, will I receive a refund?
Yes! You'll find that most hotel bookings are refundable if you cancel before the hotel's cancellation deadline, which is usually within 24-48 hours of the scheduled arrival. If your reservation is non-refundable, you might be able to still cancel and receive a refund within 24 hours of booking. Filter your search by fully refundable to find flexible hotel deals in O Brien.
What are some accommodation options with pools in O Brien?
Holiday Inn Express & Suites Alachua - Gainesville Area by IHG: Offers buffet, an outdoor pool and complimentary high-speed (wired) Internet access. Royal Springs Riverfront Retreat on 3 acres, kayak/canoe, boat ramp, huge decks! and La Quinta Inn & Suite by Wyndham Lake City are two additional hotels that feature an on-site pool. View all hotels with pools in O Brien.
How is it to stay in O Brien?
Visitors to O Brien will definitely find plenty to explore and enjoy. In O Brien, there are 11 hotels and other accommodation options to choose from. Find out more about O Brien.
What are the top places to visit in O Brien?
Natural beauty is on display at Suwannee River, Ichetucknee River and Ichetucknee Springs State Park. You'll also find Troy Spring State Park and Wes Skiles Peacock Springs State Park in the area. Take a look at what more there is to see and do in Expedia's O Brien guide.
What's the seasonal weather in O Brien?
The hottest months are usually July and August, with an average temperature of 27°C, while the coldest months are January and February, with an average of 14°C. Average annual precipitation for O Brien is 1278 mm.

Explore a world of travel with Expedia