Panacea hotels from HK$703

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Our top choices for Panacea hotels

The Panacea Motel

The Panacea Motel
2.0 star property
Panacea
9.0 out of 10, Wonderful, (139)
"A v nice place to stay "
United States
Harry
The Panacea Motel

The Lodge at Wakulla Springs

The Lodge at Wakulla Springs
3.0 star property
Crawfordville
9.4 out of 10, Exceptional, (1002)
"Great stay. Boat tour was enjoyable. Quiet relaxing place"
United States
PATRICIA
The Lodge at Wakulla Springs

Best Western Wakulla Inn & Suites

Best Western Wakulla Inn & Suites
2.5 star property
Crawfordville
8.8 out of 10, Excellent, (947)
"Great hotel. Very good customer service and very clean"
United States
claudina
The price is HK$865
HK$964 total
includes taxes & fees
7 Jan - 8 Jan 2026
Best Western Wakulla Inn & Suites

Wildwood Inn

Wildwood Inn
3.0 star property
Crawfordville
8.6 out of 10, Excellent, (1001)
"Enjoyed our stay and would definitely stay again!"
United States
Corey
The price is HK$893
HK$1,027 total
includes taxes & fees
7 Jan - 8 Jan 2026
Wildwood Inn

Franklin Inn

Franklin Inn
2.0 star property
Carrabelle
7.8 out of 10, Good, (456)
"JJ was great great location clean room comfortable bed and good value. "
United States
Crystal
The price is HK$636
HK$703 total
includes taxes & fees
13 Jan - 14 Jan 2026
Franklin Inn

St James Bay Golf & Pickleball Resort

St James Bay Golf & Pickleball Resort
3.5 star property
Carrabelle
9.0 out of 10, Wonderful, (371)
"Everytging was nice. We enjoyed our stay. Would recommend to others. "
United States
Michael
The price is HK$1,097
HK$1,212 total
includes taxes & fees
1 Jan - 2 Jan 2026
St James Bay Golf & Pickleball Resort

The Old Carrabelle Hotel

The Old Carrabelle Hotel
2.0 star property
Carrabelle
10.0 out of 10, Exceptional, (1)
The price is HK$963
HK$1,065 total
includes taxes & fees
21 Jan - 22 Jan 2026
The Old Carrabelle Hotel

The Moorings Hotel and Marina

The Moorings Hotel and Marina
2.5 star property
Carrabelle
8.4 out of 10, Very good, (39)
"Hotel was really nice and convenient to everything we wanted to do in the area. Very quiet and peaceful. Bed was a little uncomfortable, but that's a personal preference thing and I won't fault them for that. Really nice staff and easy check in and check out. Would definitely return!"
United States
Cheryl
The price is HK$1,020
HK$1,128 total
includes taxes & fees
25 Dec - 26 Dec
The Moorings Hotel and Marina
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Showing deals for:2 Jan - 4 Jan
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Stay near popular Panacea attractions

Learn more about Panacea

Kayak through pristine coastal marshes at Panacea's Woolley Park, where fishing piers and boardwalks offer prime spots for catching redfish. Nearby St. Marks National Wildlife Refuge invites visitors to spot migratory birds and explore the historic lighthouse along scenic hiking trails.

Sunset over a lake at Panacea, northern Florida, USA | NONE |

Top Panacea Hotel Reviews

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Hotels in Panacea with star-rating

Find out more about Panacea

Top reasons to visit Panacea

  • Stunning Beaches: Panacea boasts beautiful beaches ideal for relaxation and water activities, creating a perfect seaside getaway.
  • Outdoor Adventures: The area offers numerous recreational activities, including swimming, golfing, and barbeque facilities for outdoor enthusiasts.
  • Proximity to Nature: Nearby state parks and charming islands provide captivating scenery and opportunities for exploration.
  • Charming Accommodations: A variety of guesthouses and hotels cater to all travellers, many offering pet-friendly services.
  • Welcoming Community: The vibrant atmosphere influenced by nearby Florida State University adds to the friendly vibe of the area.

Find great hotels near Panacea

In Panacea, Florida, you'll discover a delightful selection of accommodation options, from charming guesthouses to comfortable hotels. Many establishments cater to adventurous travellers and families alike, offering pet-friendly services and amenities for a memorable stay. With air conditioning, complimentary Wi-Fi, and private pools available, you're sure to find the perfect retreat to unwind after exploring the area's natural beauty.

  • Hyatt House Tallahassee Capitol – University: Nestled 46.7km from Panacea, the Hyatt House Tallahassee Capitol – University is an ideal choice for those seeking a family-friendly and pet-friendly environment. This 3-star hotel seamlessly combines comfort and practicality, making it perfect for business travellers and families alike. With amenities designed for children, including complimentary cribs and window guards, this property ensures a safe and enjoyable experience for younger guests. Additionally, it welcomes pets with a variable fee policy, allowing you to bring your furry companions along for the adventure.
  • Best Western Wakulla Inn & Suites: Located a mere 9.7km from Panacea, the Best Western Wakulla Inn & Suites is a haven for those with a thirst for adventure. This hotel is tailored for active travellers, providing easy access to a variety of outdoor activities such as sailing, kayaking, and snorkelling. Whether you're seeking relaxation or excitement, this accommodation offers an array of recreational opportunities both onsite and nearby, making it a fantastic choice for business travellers who appreciate a dash of adventure during their stay.
  • Wildwood Inn: Just 11.3km from Panacea, the Wildwood Inn is a charming 3-star lodging option that caters to adventurous souls and pet lovers alike. It provides an abundance of outdoor activities, including fishing, mountain biking, and boat tours, ensuring that every guest can find their perfect adventure. The property also welcomes pets, with a fee-waived policy for service animals, allowing you to enjoy your stay with your beloved pets. With its blend of adventure and comfort, the Wildwood Inn is a splendid choice for those looking to explore the great outdoors.

Where to stay in and around Panacea

Panacea, Florida, offers a delightful blend of beachside relaxation and outdoor adventures. Just a stone's throw from the charming Apalachicola area, visitors can enjoy serene scenery and family-friendly recreation. Explore the nearby Apalachee Parkway and soak in the vibrant atmosphere influenced by the proximity to Florida State University. Whether you seek a secluded escape or a friendly community vibe, Panacea and its surroundings promise an unforgettable experience.

  • Sopchoppy: Nestled a mere 9.7km from Panacea, Sopchoppy is a charming city that offers a delightful blend of outdoor adventure and scenic beauty. Known for its seasonal influx of visitors, particularly from March to April and July, this locale is a haven for nature enthusiasts. Here, you can explore the nearby national state park, partake in recreational activities, or enjoy a round of golf. The picturesque surroundings, including serene lakes and stunning beaches, make Sopchoppy an ideal destination for those seeking a tranquil yet adventurous experience.
  • Alligator Point: Situated in close proximity to Panacea, Alligator Point is a quaint village famed for its stunning beaches and outdoor activities. Unlike other nearby areas, its visitor numbers remain fairly consistent year-round, peaking from May to July. The village is a paradise for beach lovers and outdoor enthusiasts alike, offering recreational areas, resorts, and golf courses. The nearby wetlands and national state park provide a unique opportunity for wildlife viewing and exploration, making Alligator Point a perfect spot for those looking to immerse themselves in nature.
  • Saint Teresa: Also located near Panacea, Saint Teresa is a delightful village that attracts visitors for its beautiful beaches and outdoor scenery. With peak travel times in March and June to July, this area offers a moderately seasonal experience. Visitors can enjoy various activities, including exploring nearby recreational areas, resorts, and golf facilities. The village is particularly unique for its nudist beach, catering to those seeking a different kind of seaside experience. The surrounding national state park adds to the allure, making Saint Teresa a must-visit for outdoor and beach lovers.

Things to do in and around Panacea

Panacea offers a delightful beach and outdoor experience, perfect for those seeking an active getaway. Popular activities include enjoying the scenic recreational areas, relaxing at resorts, and playing a round of golf. Visitors can indulge in swimming, utilise barbeque facilities, and immerse themselves in the beach atmosphere, making it an ideal destination for a memorable beach getaway.

Shopping

In Panacea, you can enjoy local shopping at various spots. If you're up for a drive, the Tallahassee Downtown Market, located 46.7km away, offers a vibrant atmosphere. The Governor's Square Mall, also 46.7km away, provides a mix of entertainment and family-friendly shops. Woodville Commons is 35.4km away, featuring a blend of city and family vibes.

Recreation

Woolley Park invites you to unwind in its serene surroundings, perfect for relaxation and leisurely strolls. At Myron B Hodge City Park, enjoy rejuvenating outdoor activities in a tranquil setting. For golf enthusiasts, St. James Bay Golf Club offers a stunning course just 20.9km away, blending sport with nature.

Adventure

Explore the Tallahassee-Saint Marks Historic Railroad Trail State Park, a scenic hiking trail located 43.5km from Panacea, perfect for outdoor enthusiasts. Alternatively, visit the Tom Brown Tennis Center for thrilling adventure activities, situated 49.9km away, or hike the Tallahassee-St. Marks Historic Railroad State Trail, 46.7km from Panacea, for more stunning views.

Nightlife

Experience the vibrant nightlife at Theatre Tallahassee, located 49.9km from Panacea. Enjoy captivating performances that blend romance, entertainment, and culture, making it a perfect spot for an enchanting evening out.

*Distances are measured in a straight line; actual driving distances may vary depending on the route.

Booking tips and Expedia advantages for Panacea

To save on your trip to Panacea, consider visiting in July or between December and January for lower accommodation prices, avoiding the pricier months of May and September to October. Booking on a Monday can also cut costs, while Friday is the most expensive. Use Expedia's search tool to find eco-friendly hotels and sort by price to uncover the best deals. Additionally, consider bundling your hotel, flights, and activities for extra savings. Look out for app deals and special offers to maximise your budget while enjoying your stay.

  • The most and least expensive months on average to stay in a hotel: The cheapest months to stay in Panacea are July and December to January, where the prices are slightly lower. This is in comparison to May and September to October, where prices are slightly higher.
  • The most and least expensive days on average to stay in a hotel: The least expensive day to stay in Panacea is Monday. The most expensive day to stay in Panacea is Friday.
  • Find cheap hotels on Expedia: Utilise Expedia's search tool to refine your preferences, including your budget, desired location, and the type of hotel you wish to stay in. For instance, selecting the Eco-certified filter will showcase sustainable and environmentally-friendly hotels currently available. To discover the most affordable prices and offers, arrange the price filter from lowest to highest.
  • Consider bundling your trip: You can save money by combining your Panacea hotel booking with your flights and activities through an Expedia package.

Find the best attractions in Panacea

Panacea, Florida, is an idyllic destination for those seeking beach, outdoor, and scenic experiences. With its stunning beaches, nearby state parks, and charming islands, visitors will find a wealth of attractions to explore. Whether you're looking to relax by the shore or immerse yourself in nature, Panacea offers a variety of points of interest that cater to all outdoor enthusiasts and beach lovers alike.

  • Alligator Point Beach: Experience the tranquil beach vibes at Alligator Point Beach, where soft sands meet gentle waves. Perfect for relaxation, sunbathing, and casual strolls along the shoreline, this beach offers a peaceful retreat amidst nature’s beauty.
  • Bald Point State Park: Embrace adventure in Bald Point State Park, known for its stunning scenery and diverse wildlife. Explore scenic trails, enjoy birdwatching, and take in breathtaking views of the coast, making it an ideal spot for outdoor enthusiasts.
  • Panacea Springs: Visit Panacea Springs, a charming urban park perfect for family outings. With lush greenery, picnic areas, and walking paths, it provides a delightful escape from the city while fostering a sense of community and relaxation.

Best time to go to Panacea

The best time to visit Panacea is dependent on what kind of holiday you are seeking. July and August are its hottest month on average. At the time of August, visitor numbers are average and weather is mostly sunny. January is its coolest month on average. At this time, visitor numbers are average and weather is mostly sunny with light rain.

calendarCalendar MonthtemperatureTemperaturerainPrecipitationmostlyCloudinessoccupationOccupancypricePricing
January53.6°F (12.0°C)Light RainMostly SunnyAverageSlightly Low
February57.6°F (14.2°C)Light RainMostly SunnyAverageAverage
March62.4°F (16.9°C)Light RainMostly SunnyAverageAverage
April68.2°F (20.1°C)Light RainMostly SunnyModerately HighAverage
May74.8°F (23.8°C)Light RainMostly SunnyAverageSlightly High
June80.4°F (26.9°C)Moderate RainMostly SunnyModerately HighAverage
July81.7°F (27.6°C)Moderate RainMostly SunnyModerately HighSlightly Low
August81.7°F (27.6°C)Moderate RainMostly SunnyAverageAverage
September78.4°F (25.8°C)Light RainMostly SunnyAverageSlightly High
October71.1°F (21.7°C)Light RainMostly SunnyModerately LowSlightly High
November61.9°F (16.6°C)Light RainMostly SunnyModerately LowAverage
December57.6°F (14.2°C)Light RainMostly SunnyModerately LowSlightly Low

The nearest major airports for your trip to Panacea

Flying into Panacea, Florida, is convenient via Tallahassee International Airport (TLH), located 41.8km away. Several excellent hotel options can be found nearby, such as the DoubleTree by Hilton Hotel Tallahassee and Hotel Duval, both rated 4 stars and situated 8.0km from the airport, offering reliable transportation services for easy access. Another option is Hotel Indigo Tallahassee - Collegetown by IHG, a 3.5-star hotel located 6.4km from TLH. Each of these hotels provides convenient transfers to ensure a seamless journey from the airport to your accommodation, making your visit to Panacea a pleasant experience.

Frequently asked questions

Where is the best place to stay in Panacea?
Based on Expedia's traveller preferences, The Panacea Motel is a top place to stay in Panacea. Other good choices for your trip include Skipper-extends from Beach Front to Harbor with Kayaks, Pickleball & Dock and "Shifting Sands" Private Beach Front 3 Bd, 2 Bath, sleeps 8. See all available top hotels, or vacation rentals in Panacea.
What are some of the best holiday rentals that Panacea has to offer?
Oceanfront on a Private Beach-Hot Tub-Beautifully Remodeled-Dog Friendly Beach: This highly rated holiday home rental in Panacea is located on the beach, and has a fireplace, a balcony and a BBQ to put you at ease in your new surroundings. It has 3 bedrooms, as well as a kitchen with a dishwasher, a fridge and a stovetop, so that you can cook with friends or family. It offers a garden, a selection of games and 1 hot tub so that you can immerse yourself in your holiday. Other favourite homes for rent in Panacea are Skipper-extends from Beach Front to Harbor with Kayaks, Pickleball & Dock and NEW LISTING!!! Welcome to Ohana Shack! 4BR/4.5BA Private Beachfront Property!. See all vacation rentals in Panacea.
If I need to cancel my hotel reservation in Panacea, will I receive a refund?
Yes, the majority of hotel bookings are refundable provided that you cancel before the hotel's cancellation deadline, which is usually within 24-48 hours of your scheduled arrival. If you have a reservation that's non-refundable, you may still be able to cancel and be given a refund within a 24-hour period of booking. Filter your search by fully refundable to find flexible hotel deals in Panacea.
What's the best dog-friendly place to stay in Panacea?
The Panacea Motel is a top dog-friendly option for your stay. See more pet-friendly hotel accommodations in Panacea.
What are some accommodation options with pools in Panacea?
7 Bedroom Beach House with POOL!! Gulf Front and Bay Front: Offers complimentary wireless Internet access, a pool and kitchens. View all hotels with pools in Panacea.
How is it to stay in Panacea?
Nature enthusiasts will enjoy exploring Panacea, and many visitors will definitely appreciate the beaches and seafood restaurants. The relaxing and secluded setting also entices those visiting the city. In Panacea, there are 213 hotels and other accommodation options to choose from. Find out more about Panacea.
What are the top places to visit in Panacea?
Natural beauty is on display at Mashes Sand Beach, Alligator Point Beach and Bald Point State Park. Dolphin viewing is a great activity, and Bayside Marina is one place to visit. A couple of additional sights to add to your itinerary are Wilson Beach and Alligator Harbor Aquatic Preserve. Take a look at what more there is to see and do in Expedia's Panacea guide.
What's the seasonal weather in Panacea?
The hottest months are usually July and August, with an average temperature of 27°C, while the coldest months are January and February, with an average of 14°C. The rainiest months in Panacea are August, July, June and September, with each month seeing an average of 201 mm of rainfall.

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