Santa Ana hotels in Antigua Guatemala

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Our top choices for Santa Ana hotels

Casa Buho B&B

Casa Buho B&B
3.0 star property
Santa Ana
9.2 out of 10, Wonderful, (48 reviews)
"Great place !!"
United States
Abner Israel Polanco
The price is HK$434
HK$530 total
includes taxes & fees
19 Jan - 20 Jan
Casa Buho B&B

Villas Santa Ana-Ricardo

Villas Santa Ana-Ricardo
3.5 star property
Santa Ana
8.6 out of 10, Excellent, (12 reviews)
"Space was clean and had a cozy vibe."
United States
Evelin
Villas Santa Ana-Ricardo

Hostal Casa Buho

Hostal Casa Buho
3.0 star property
Santa Ana
8.6 out of 10, Excellent, (22 reviews)
"A little too far from everything but as long as you have a car is ok plenty of parking there"
United States
Gustavo
The price is HK$342
HK$424 total
includes taxes & fees
29 Jan - 30 Jan
Hostal Casa Buho

Hotel Posada del Angel

Hotel Posada del Angel
4.0 star property
1 km from Santa Ana
9.6 out of 10, Exceptional, (283 reviews)
"The breakfast on the rooftop where we could watch the volcano erupt was spectacular. Breakfast was delicious and service was top notch. We stayed in the Rose Suite and loved it."
United States
Amelia
Hotel Posada del Angel

Pensativo House Hotel

Pensativo House Hotel
4.5 star property
1 km from Santa Ana
9.4 out of 10, Exceptional, (393 reviews)
"Rooms were clean and bed and pillows were comfortable with good A/C. Staff was very helpful and were always ready to assist. Food was excellent. "
United States
Carlos Alvarez
Pensativo House Hotel

Las Cruces Boutique Hotel

Las Cruces Boutique Hotel
4.0 star property
Historic Center, 1.4 km from Santa Ana
9.8 out of 10, Exceptional, (227 reviews)
"Everything is amazing. This hotel is beautiful!! The staff is awesome!!"
United States
Denise
The price is HK$1,949
HK$2,378 total
includes taxes & fees
19 Jan - 20 Jan
Las Cruces Boutique Hotel

Meson Panza Verde

Meson Panza Verde
3.5 star property
1.1 km from Santa Ana
9.2 out of 10, Wonderful, (439 reviews)
"Great location "
United States
Jami
The price is HK$1,150
HK$1,431 total
includes taxes & fees
21 Jan - 22 Jan
Meson Panza Verde

Ciel-Luxe Hotels

Ciel-Luxe Hotels
3.5 star property
Historic Center, 1.4 km from Santa Ana
8.6 out of 10, Excellent, (361 reviews)
"Excellent customer service from the staff, great food, room was very clean and a block away from the park."
United States
Rodrigo
Ciel-Luxe Hotels

Hotel Cacique Real

Hotel Cacique Real
3.0 star property
1.8 km from Santa Ana
8.8 out of 10, Excellent, (163 reviews)
"Very clean rooms and nice outdoor area plus secure parking lot"
United States
Ephraim
Hotel Cacique Real

San Rafael Hotel

San Rafael Hotel
4.0 star property
Historic Center, 1.5 km from Santa Ana
9.8 out of 10, Exceptional, (444 reviews)
"Helpful and courteous staff, clean room, excellent location and beautiful common areas. Super quiet and peaceful. "
United States
Ricardo
The price is HK$1,540
HK$1,923 total
includes taxes & fees
30 Jan - 31 Jan
San Rafael Hotel

Don Valentino

Don Valentino
3.5 star property
Historic Center, 1.6 km from Santa Ana
7.4 out of 10, Good, (77 reviews)
"Great service! Clean rooms and the young guy in front desk was very attentive and helpful. "
United States
Azucena
The price is HK$359
HK$438 total
includes taxes & fees
16 Jan - 17 Jan
Don Valentino

Casa Noble Hotel

Casa Noble Hotel
3.0 star property
0.9 km from Santa Ana
9.6 out of 10, Exceptional, (176 reviews)
"Staff was great, breakfast was lovely. Would recommend. "
United States
Kristi
The price is HK$858
HK$1,047 total
includes taxes & fees
2 Feb - 3 Feb
Casa Noble Hotel

Hotel Casa Bansley

Hotel Casa Bansley
2.5 star property
2.3 km from Santa Ana
9.8 out of 10, Exceptional, (47 reviews)
"Property is beautiful and staff are great"
United States
Michael
The price is HK$827
HK$1,009 total
includes taxes & fees
18 Jan - 19 Jan
Hotel Casa Bansley

Luna Maya Boutique Hotel

Luna Maya Boutique Hotel
3.0 star property
1.5 km from Santa Ana
9.6 out of 10, Exceptional, (22 reviews)
"Really nice experience. Room was clean and the staff was very friendly. Will go back again."
United States
Wilfredo
The price is HK$514
HK$627 total
includes taxes & fees
26 Jan - 27 Jan
Luna Maya Boutique Hotel

Naif Boutique Hotel

Naif Boutique Hotel
3.0 star property
Historic Center, 1.4 km from Santa Ana
9.0 out of 10, Wonderful, (382 reviews)
"Beautiful rooms and helpful staff in a very nicely centrally located hotel"
United States
Joe
The price is HK$965
HK$1,178 total
includes taxes & fees
22 Jan - 23 Jan
Naif Boutique Hotel

Why Not Hotel

Why Not Hotel
3.0 star property
Historic Center, 1.5 km from Santa Ana
8.4 out of 10, Very good, (153 reviews)
"clean and spacious room "
Italy
Teresa
The price is HK$398
HK$485 total
includes taxes & fees
19 Jan - 20 Jan
Why Not Hotel

Indian Palace

Indian Palace
3.0 star property
2.8 km from Santa Ana
9.2 out of 10, Wonderful, (29 reviews)
"Beautiful view to the volcanics clean area Beautiful pool, good game room i will recommend."
United States
Estuardo
The price is HK$618
HK$754 total
includes taxes & fees
16 Jan - 17 Jan
Indian Palace

Casa Santa Rosa Hotel Boutique

Casa Santa Rosa Hotel Boutique
3.5 star property
Historic Center, 1.4 km from Santa Ana
9.6 out of 10, Exceptional, (329 reviews)
"Best place to stay in Antigua!!"
United States
Maria
The price is HK$1,220
HK$1,488 total
includes taxes & fees
9 Feb - 10 Feb
Casa Santa Rosa Hotel Boutique

Hotel Meson de Maria

Hotel Meson de Maria
3.5 star property
Historic Center, 1.6 km from Santa Ana
9.0 out of 10, Wonderful, (191 reviews)
"Beautiful property and very friendly staff! The breakfast is also very good!"
United States
Monty
Hotel Meson de Maria

All Suite El Marques de Antigua

All Suite El Marques de Antigua
3.5 star property
1 km from Santa Ana
9.4 out of 10, Exceptional, (320 reviews)
"Very clean, excellent location and super friendly staff"
United States
Aliasger
All Suite El Marques de Antigua
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Where to stay in Santa Ana

Find the best Santa Ana areas for the activities you enjoy most.

Historic Center

If you're spending some time in Historic Center, Central Park and Santa Catalina Arch are top sights worth seeing.

Barrio de La Concepción

While visiting Barrio de La Concepción, you might make a stop by sights like Casa Santo Domingo Museum and Jade Maya Factory and Museum.

Top Santa Ana Hotel Reviews

Frequently asked questions

What's it like in Santa Ana?
Travellers to the Santa Ana neighbourhood in Antigua Guatemala will be sure to enjoy their stay.
What's a favourite place to stay in Santa Ana?
Based on Expedia customer reviews, Casa Buho B&B is the highest ranked property in Santa Ana. This hotel offers a restaurant and free parking.
How many hotels will I be able to find in Santa Ana?
If you're searching for places to stay in Antigua Guatemala, choose from one of Expedia's 17 hotels and other accommodation options in Santa Ana.
If I need to cancel my hotel reservation in Santa Ana, will I receive a refund?
Yes! You'll find that most hotel reservations are fully refundable provided that you cancel prior to the hotel's cancellation deadline, which in most cases is within 24 or 48 hours of your scheduled arrival. If you booked a non-refundable reservation, it may still be possible to cancel it and be given a refund within 24 hours of your booking. Enter your dates, click on "Search", then use the "fully refundable" filter to view top deals in Santa Ana.
What are the top things to see and do in Santa Ana?
House of the Giants, Santa Clara Convent and Jade Maya Factory and Museum are just a few of the places to visit in and around Santa Ana. While you're out sightseeing in Antigua Guatemala, make sure that you visit other sights such as Tanque La Unión or Museo del Hermano Pedro.