Santa Ana hotels in Antigua Guatemala

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Our top choices for Santa Ana hotels

Hostal Casa Buho

Hostal Casa Buho
3.0 star property
Santa Ana
8.6 out of 10, Excellent, (24 reviews)
"A little too far from everything but as long as you have a car is ok plenty of parking there"
United States
Gustavo
The price is HK$381
HK$467 total
includes taxes & fees
22 Apr - 23 Apr
Hostal Casa Buho

Villas Santa Ana-Ricardo

Villas Santa Ana-Ricardo
3.5 star property
Santa Ana
8.8 out of 10, Excellent, (15 reviews)
"Space was clean and had a cozy vibe."
United States
Evelin
The price is HK$874
HK$1,095 total
includes taxes & fees
28 Apr - 29 Apr
Villas Santa Ana-Ricardo

Casa Buho B&B

Casa Buho B&B
3.0 star property
Santa Ana
9.2 out of 10, Wonderful, (51 reviews)
"Beautiful hotel with clean rooms and friendly staff. The only downsides are the distance to the center (a 30-minute walk) and the chickens and peacocks screaming early in the morning"
United States
Patrick
The price is HK$514
HK$627 total
includes taxes & fees
23 Apr - 24 Apr
Casa Buho B&B

La guarida del caudillo

La guarida del caudillo
1.0 star property
Santa Ana
The price is HK$202
HK$249 total
includes taxes & fees
22 May - 23 May
La guarida del caudillo

Castillo De Los Gigantes

Castillo De Los Gigantes
2.0 star property
Santa Ana
6.0 out of 10, (1 review)
"This property should be listed on Airbnb, it is not a hostel/hotel, it's more like a spare room in someone's home. There's nothing nearby. It was a saviour during semana santa, but otherwise not a particularly good place to stay. That being said the people were lovely, and the room was decent for the price."
American Samoa
Ella
The price is HK$116
HK$236 total
includes taxes & fees
5 May - 6 May
Castillo De Los Gigantes

Tikal Futura Hotel & Convention Center

Tikal Futura Hotel & Convention Center
4.5 star property
20.1 km from Santa Ana
9.2 out of 10, Wonderful, (1,007 reviews)
"The room was very nice and clean, very goods staff "
United States
Benigno
The price is HK$887
HK$1,082 total
includes taxes & fees
18 May - 19 May
Tikal Futura Hotel & Convention Center

Mestizo Cortijo

Mestizo Cortijo
3.0 star property
4.3 km from Santa Ana
8.8 out of 10, Excellent, (127 reviews)
"Friendly staff, beautiful room, great location!"
United States
David
The price is HK$931
HK$1,136 total
includes taxes & fees
3 May - 4 May
Mestizo Cortijo

Kawilal Hotel

Kawilal Hotel
3.5 star property
13.9 km from Santa Ana
9.0 out of 10, Wonderful, (139 reviews)
"The property is absolutely gorgeous and the staff is wonderful. On site restaurant is small but a decent amount to select from to eat. Rooms are clean and comfortable. "
United States
Rochelle
The price is HK$1,057
HK$1,290 total
includes taxes & fees
4 May - 5 May
Kawilal Hotel

Los Faroles Hotel & Spa

Los Faroles Hotel & Spa
3.0 star property
2.3 km from Santa Ana
8.8 out of 10, Excellent, (5 reviews)
"Los Faroles Hotel y Spa was AMAZING! If I could rate 6 stars out of 5, I totally would. Luisa met us during check in, and she made us feel so welcome. Breakfast was included and delicious. One day during our stay we left early to go to Acatenango, and the staff made sure we had break packed and ready to go. When I needed help with my car reservation to get back to the airport, the staff helped me talk to the car company and driver. The rooms are simple and beautiful. The rooftop terrace offers...
United States
Phoenix
The price is HK$717
HK$875 total
includes taxes & fees
27 Apr - 28 Apr
Los Faroles Hotel & Spa

Hostal Donde Regina

Hostal Donde Regina
3.0 star property
21 km from Santa Ana
9.0 out of 10, Wonderful, (189 reviews)
"Close to the airport, helpful staff, cozy atmosphere, clean and unique rooms "
United States
Elizabeth
The price is HK$391
HK$477 total
includes taxes & fees
3 May - 4 May
Hostal Donde Regina

Barceló Guatemala City

Barceló Guatemala City
4.5 star property
22.7 km from Santa Ana
9.2 out of 10, Wonderful, (3,298 reviews)
"Wonderful breakfast buffet."
United States
MARIA
The price is HK$861
HK$1,050 total
includes taxes & fees
12 May - 13 May
Barceló Guatemala City

Hotel Vista Quince

Hotel Vista Quince
5.0 star property
25.5 km from Santa Ana
8.6 out of 10, Excellent, (255 reviews)
"Staff very pleasant and service oriented "
Canada
osbin
The price is HK$987
HK$1,204 total
includes taxes & fees
1 May - 2 May
Hotel Vista Quince

Hotel y Restaurante Vista Verde

Hotel y Restaurante Vista Verde
3.0 star property
5.9 km from Santa Ana
9.4 out of 10, Exceptional, (12 reviews)
"Great room (#3) with high quality mattress, nice towels and pretty bathroom, lacks some toiletries, quiete place with awesome graden views, property rune by their owners, highly recommended! "
United States
Sergio
The price is HK$566
HK$698 total
includes taxes & fees
4 May - 5 May
Hotel y Restaurante Vista Verde

AC Hotel by Marriott Guatemala City

AC Hotel by Marriott Guatemala City
4.0 star property
26.4 km from Santa Ana
8.6 out of 10, Excellent, (1,003 reviews)
"Convenient Great location Great for business travel "
United States
Patricia
The price is HK$992
HK$1,210 total
includes taxes & fees
3 May - 4 May
AC Hotel by Marriott Guatemala City

The Westin Camino Real, Guatemala

The Westin Camino Real, Guatemala
4.5 star property
23 km from Santa Ana
9.2 out of 10, Wonderful, (1,006 reviews)
"Great location"
United States
Maria Teresa
The price is HK$1,050
HK$1,281 total
includes taxes & fees
26 Apr - 27 Apr
The Westin Camino Real, Guatemala

Casa Aurora

Casa Aurora
3.0 star property
20.9 km from Santa Ana
8.8 out of 10, Excellent, (173 reviews)
"Close to the airport and clean roomand staff are very friendly ."
United States
Darren
The price is HK$358
HK$437 total
includes taxes & fees
24 Apr - 25 Apr
Casa Aurora

Hotel Museo Spa Casa Santo Domingo

Hotel Museo Spa Casa Santo Domingo
4.5 star property
Barrio de La Concepción, 1.1 km from Santa Ana
9.2 out of 10, Wonderful, (1,055 reviews)
"Gorgeous hotel, clean room, friendly, helpful staff fascinating museum."
United States
Melissa
The price is HK$1,973
HK$2,503 total
includes taxes & fees
30 Apr - 1 May
Hotel Museo Spa Casa Santo Domingo

Hilton Guatemala City

Hilton Guatemala City
4.5 star property
25.9 km from Santa Ana
8.6 out of 10, Excellent, (710 reviews)
"Yes room very clean … ornate decor…. Bed comfortable and spacious… staff helpful and courteous."
United States
karen
The price is HK$793
HK$967 total
includes taxes & fees
3 May - 4 May
Hilton Guatemala City

Good Hotel Guatemala City

Good Hotel Guatemala City
3.0 star property
23.9 km from Santa Ana
9.4 out of 10, Exceptional, (322 reviews)
"Modern rooms, very clean and very friendly staff "
Germany
Julia
The price is HK$872
HK$1,064 total
includes taxes & fees
13 May - 14 May
Good Hotel Guatemala City

Santo Cielo by Casa Santo Domingo

Santo Cielo by Casa Santo Domingo
3.5 star property
0.9 km from Santa Ana
9.4 out of 10, Exceptional, (543 reviews)
"Comfy, quiet, always enjoy staying here."
United States
Clara del Carmen
The price is HK$1,663
HK$2,125 total
includes taxes & fees
22 Apr - 23 Apr
Santo Cielo by Casa Santo Domingo
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Where to stay in Santa Ana

Find the best Santa Ana areas for the activities you enjoy most.

Historic Center

If you're spending some time in Historic Center, Central Park and Santa Catalina Arch are top sights worth seeing.

Barrio de La Concepción

While visiting Barrio de La Concepción, you might make a stop by sights like Casa Santo Domingo Museum and Jade Maya Factory and Museum.

Top Santa Ana Hotel Reviews

Frequently asked questions

What's it like in Santa Ana?
Travellers to the Santa Ana neighbourhood in Antigua Guatemala will be sure to enjoy their stay.
What's a favourite place to stay in Santa Ana?
Based on our traveller data, Casa Buho B&B is one of the top choices for your stay in Santa Ana. This hotel offers a restaurant and free parking.
How many hotels will I be able to find in Santa Ana?
If you're searching for places to stay in Antigua Guatemala, choose from one of Expedia's 14 hotels and other accommodation options in Santa Ana.
If I need to cancel my hotel reservation in Santa Ana, will I receive a refund?
Yes! You'll find that most hotel reservations are fully refundable provided that you cancel prior to the hotel's cancellation deadline, which in most cases is within 24 or 48 hours of your scheduled arrival. If you booked a non-refundable reservation, it may still be possible to cancel it and be given a refund within 24 hours of your booking. Enter your dates, click on "Search", then use the "fully refundable" filter to view top deals in Santa Ana.
What are the top things to see and do in Santa Ana?
House of the Giants, Santa Clara Convent and Jade Maya Factory and Museum are just a few of the places to visit in and around Santa Ana. While you're out sightseeing in Antigua Guatemala, make sure that you visit other sights such as Tanque La Unión or Museo del Hermano Pedro.