Southeast Missouri hotels from HK$439

  • Change your mind

    Book hotels with free cancellation
  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
  • Be picky

    Search almost a million properties worldwide

Check prices for these dates

Next weekend
In two weeks

Filter by

Guest rating
Guest rating
Star rating

Our top choices for Southeast Missouri hotels

Drury Plaza Hotel Cape Girardeau Conference Center

Drury Plaza Hotel Cape Girardeau Conference Center
3.0 star property
Cape Girardeau
9.6 out of 10, Exceptional, (1,008 reviews)
"Great place "
United States
Kelly
The price is HK$780
HK$880 total
includes taxes & fees
1 Feb - 2 Feb
Drury Plaza Hotel Cape Girardeau Conference Center

Drury Inn & Suites Jackson MO

Drury Inn & Suites Jackson MO
3.0 star property
Jackson
9.6 out of 10, Exceptional, (1,006 reviews)
"Suited our purpose for overnight on a road trip "
United States
Angela
Drury Inn & Suites Jackson MO

The Farmstead Hotel

The Farmstead Hotel
2.5 star property
Caruthersville
8.8 out of 10, Excellent, (477 reviews)
"Clean room, very nice staff"
United States
Mack
The price is HK$593
HK$674 total
includes taxes & fees
26 Jan - 27 Jan
The Farmstead Hotel

Echo Bluff State Park

Echo Bluff State Park
2.5 star property
Eminence
9.4 out of 10, Exceptional, (221 reviews)
"This entire trip was inspired by Tina, a staff member. I met Tina passing through the area and she provided me with a lot of information which gave me the idea to plan a weekend trip with my wife. The lodge room we had was clean and comfortable, My wife and I had a wonderful time exploring most of the areas Tina mentioned. Thank you Tina for a wonderful inspiration for a get away. "
United States
Jared
The price is HK$1,229
HK$1,299 total
includes taxes & fees
26 Jan - 27 Jan
Echo Bluff State Park

Fairfield Inn & Suites by Marriott Sikeston

Fairfield Inn & Suites by Marriott Sikeston
2.5 star property
Sikeston
9.2 out of 10, Wonderful, (52 reviews)
"The room was very clean, and the staffwere very easy to work with and accommodating. "
United States
Lacie
The price is HK$788
HK$892 total
includes taxes & fees
1 Feb - 2 Feb
Fairfield Inn & Suites by Marriott Sikeston

The Riverview

The Riverview
4.0 star property
Cape Girardeau
9.4 out of 10, Exceptional, (493 reviews)
"The room was clean and I was able to check in a bit early."
United States
Sara
The price is HK$728
HK$822 total
includes taxes & fees
26 Jan - 27 Jan
The Riverview

Tru By Hilton Cape Girardeau

Tru By Hilton Cape Girardeau
2.5 star property
Cape Girardeau
9.6 out of 10, Exceptional, (108 reviews)
"Very nice room!"
United States
Niki
The price is HK$729
HK$830 total
includes taxes & fees
1 Feb - 2 Feb
Tru By Hilton Cape Girardeau

Holiday Inn Express & Suites Perryville by IHG

Holiday Inn Express & Suites Perryville by IHG
2.5 star property
Perryville
9.2 out of 10, Wonderful, (555 reviews)
"lean, updated rooms, friendly staff and great breakfast."
United States
Linda
The price is HK$710
HK$812 total
includes taxes & fees
29 Jan - 30 Jan
Holiday Inn Express & Suites Perryville by IHG

La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau

La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau
3.0 star property
Jackson
9.0 out of 10, Wonderful, (692 reviews)
"Conveniently located, clean, friendly staff."
United States
Philip
The price is HK$623
HK$674 total
includes taxes & fees
27 Jan - 28 Jan
La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau

Fairfield Inn & Suites by Marriott Poplar Bluff

Fairfield Inn & Suites by Marriott Poplar Bluff
2.5 star property
Poplar Bluff
9.4 out of 10, Exceptional, (870 reviews)
"The size of the room. The staff were great. The room was very clean. Will definitely stay there again."
United States
Brenda
The price is HK$819
HK$925 total
includes taxes & fees
31 Jan - 1 Feb
Fairfield Inn & Suites by Marriott Poplar Bluff

Holiday Inn Poplar Bluff by IHG

Holiday Inn Poplar Bluff by IHG
3.0 star property
Poplar Bluff
8.8 out of 10, Excellent, (715 reviews)
"Amazing place"
United States
Mladen
The price is HK$889
HK$1,004 total
includes taxes & fees
30 Jan - 31 Jan
Holiday Inn Poplar Bluff by IHG

Drury Inn & Suites Sikeston, MO

Drury Inn & Suites Sikeston, MO
3.0 star property
Sikeston
9.4 out of 10, Exceptional, (1,004 reviews)
"As always it was a perfect visit"
United States
John
The price is HK$702
HK$807 total
includes taxes & fees
3 Feb - 4 Feb
Drury Inn & Suites Sikeston, MO

Courtyard by Marriott Cape Girardeau Downtown

Courtyard by Marriott Cape Girardeau Downtown
3.0 star property
Cape Girardeau
9.6 out of 10, Exceptional, (483 reviews)
"Very nice hotel!"
United States
Angie
The price is HK$975
HK$1,104 total
includes taxes & fees
22 Feb - 23 Feb
Courtyard by Marriott Cape Girardeau Downtown

Hampton Inn Sikeston

Hampton Inn Sikeston
2.5 star property
Sikeston
9.0 out of 10, Wonderful, (471 reviews)
"Very clean and super friendly staff!"
United States
Katherine
The price is HK$749
HK$848 total
includes taxes & fees
8 Feb - 9 Feb
Hampton Inn Sikeston

Best Western Plus Sikeston I-55

Best Western Plus Sikeston I-55
2.5 star property
Sikeston
8.4 out of 10, Very good, (1,005 reviews)
"Great stay, everything was clean and comfortable. "
United States
Charles
The price is HK$636
HK$725 total
includes taxes & fees
30 Jan - 31 Jan
Best Western Plus Sikeston I-55

Honeysuckle Inn - Mountain View

Honeysuckle Inn - Mountain View
3.0 star property
Mountain View
8.6 out of 10, Excellent, (337 reviews)
"Staff was very friendly."
United States
Joyce
The price is HK$702
HK$761 total
includes taxes & fees
1 Feb - 2 Feb
Honeysuckle Inn - Mountain View

Fort Davidson Hotel

Fort Davidson Hotel
2.5 star property
Ironton
9.2 out of 10, Wonderful, (175 reviews)
"Fantastic local hotel that’s right next to a state historic site. A must stay if in the area"
United States
Graham
The price is HK$920
HK$1,005 total
includes taxes & fees
30 Jan - 31 Jan
Fort Davidson Hotel

Holiday Inn Express & Suites Sikeston Southwest by IHG

Holiday Inn Express & Suites Sikeston Southwest by IHG
2.5 star property
Sikeston
8.6 out of 10, Excellent, (447 reviews)
"Stay was excellent "
United States
Kourtney
The price is HK$819
HK$927 total
includes taxes & fees
1 Feb - 2 Feb
Holiday Inn Express & Suites Sikeston Southwest by IHG

Motel 6 Poplar Bluff, MO

Motel 6 Poplar Bluff, MO
2.0 star property
Poplar Bluff
8.0 out of 10, Very good, (1,002 reviews)
"Very clean and staff was very friendly!"
United States
Sherry
The price is HK$444
HK$469 total
includes taxes & fees
27 Jan - 28 Jan
Motel 6 Poplar Bluff, MO

Drury Inn & Suites Poplar Bluff

Drury Inn & Suites Poplar Bluff
3.0 star property
Poplar Bluff
9.2 out of 10, Wonderful, (985 reviews)
"Great location and room "
United States
Curtis
Drury Inn & Suites Poplar Bluff
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Holiday Rentals in Southeast Missouri

Save an average of 15% on thousands of hotels when you're signed in

Stay near popular Central United States attractions

Learn more about Southeast Missouri

Discover the family-friendly area of Southeast Missouri—wineries, a scenic riverfront and sights from K Bridge Recreation Area to Clearwater Lake.

Mini Takes the States 2014 Road Rally Memphis to St.Louis Leg:

Moark Regional Railroad Museum
HOURS: Saturdays 1 p.m. - 4 p.m.

It was not open when I stopped by but there are a few rail cars outside. Poplar has a train rich history.

This was a cool little town to stop in and take pictures. Lot's of wall murals for some reason, and some very cool architecture. Worth the stop and be sure and enjoy a lunch at Hayden's Drive-In ! 

#MTTS2014 #minitakesthestates #go11
#train
Photo by Bill Dillard
Open Photo by Bill Dillard

Top Southeast Missouri Hotel Reviews

More cheap stays in Southeast Missouri

Hotels in Southeast Missouri with star-rating

Explore a world of travel with Expedia