Southeast Missouri hotels
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Our top choices for Southeast Missouri hotels
1. Drury Inn & Suites Sikeston, MO
Drury Inn & Suites Sikeston, MOSikeston
9.6 out of 10, Exceptional, (1,005 reviews)
"Nice hotel with evening dinner and buffet breakfast."
Sally
The price is HK$870
HK$1,001 total
includes taxes & fees
15 Aug - 16 Aug
2. Madison Inn Lodge
Madison Inn LodgeFredericktown
7.6 out of 10, Good, (305 reviews)
"The owner of this place was extremely nice. So was the cleaning staff. I would definitely stay here again."
Christine
The price is HK$686
HK$750 total
includes taxes & fees
12 Aug - 13 Aug
3. Fort Davidson Hotel
Fort Davidson HotelIronton
9.2 out of 10, Wonderful, (185 reviews)
"We really enjoyed our stay. It was located near everything we wanted to do in that area. It is not a new location, but it was a good value. We would stay there again."
John
The price is HK$980
HK$1,071 total
includes taxes & fees
4 Aug - 5 Aug
4. Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG
Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHGCape Girardeau
9.4 out of 10, Exceptional, (1,002 reviews)
"Everyone was great and rooms were nice and breakfast was great."
Cris
The price is HK$863
HK$973 total
includes taxes & fees
9 Aug - 10 Aug
5. Fairfield Inn & Suites by Marriott Poplar Bluff
Fairfield Inn & Suites by Marriott Poplar BluffPoplar Bluff
9.4 out of 10, Exceptional, (945 reviews)
"Nice clean area and motel."
Jean
The price is HK$793
HK$896 total
includes taxes & fees
23 Aug - 24 Aug
6. Drury Plaza Hotel Cape Girardeau Conference Center
Drury Plaza Hotel Cape Girardeau Conference CenterCape Girardeau
9.6 out of 10, Exceptional, (1,008 reviews)
"Staff was great"
Paul
The price is HK$784
HK$885 total
includes taxes & fees
16 Aug - 17 Aug
7. Shepherd Mountain Inn
Shepherd Mountain InnIronton
9.2 out of 10, Wonderful, (325 reviews)
"This was the perfect little place for my husband and I to stay for our little vacation. Very quiet, close to many state parks and beautiful scenery. The staff was friendly, the room was clean and organized, and the breakfast was very good. We will definitely stay there again next time we are in the area."
Katie
The price is HK$967
HK$1,056 total
includes taxes & fees
4 Aug - 5 Aug
8. Hampton Inn Poplar Bluff
Hampton Inn Poplar BluffPoplar Bluff
9.4 out of 10, Exceptional, (911 reviews)
"Great overnight restful stay"
Philip
The price is HK$733
HK$821 total
includes taxes & fees
23 Aug - 24 Aug
9. Crown Pointe Lodge, BW Signature Collection
Crown Pointe Lodge, BW Signature CollectionFarmington
9.0 out of 10, Wonderful, (659 reviews)
"Very pretty area, staff was wonderful and breakfast was great slso!"
Louise
The price is HK$860
HK$936 total
includes taxes & fees
23 Aug - 24 Aug
10. Fairfield Inn & Suites by Marriott Cape Girardeau
Fairfield Inn & Suites by Marriott Cape GirardeauCape Girardeau
9.4 out of 10, Exceptional, (215 reviews)
"The staff at breakfast was wonderful!"
Heather
The price is HK$727
HK$820 total
includes taxes & fees
13 Aug - 14 Aug
11. Drury Inn & Suites Jackson MO
Drury Inn & Suites Jackson MOJackson
9.6 out of 10, Exceptional, (1,002 reviews)
"This hotel was so clean and comfy! The breakfast was awesome too!"
Jamie
The price is HK$627
HK$663 total
includes taxes & fees
16 Aug - 17 Aug
12. Black River Motel and Restaurant
Black River Motel and RestaurantLesterville
8.6 out of 10, Excellent, (44 reviews)
"Staff was very helpful and friendly"
Douglas
The price is HK$910
HK$963 total
includes taxes & fees
9 Aug - 10 Aug
13. La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau
La Quinta Inn & Suites by Wyndham Jackson/Cape GirardeauJackson
9.0 out of 10, Wonderful, (815 reviews)
"Breakfast is good."
Jkara
The price is HK$727
HK$786 total
includes taxes & fees
6 Aug - 7 Aug
14. Holiday Inn Express & Suites Sikeston Southwest by IHG
Holiday Inn Express & Suites Sikeston Southwest by IHGSikeston
8.8 out of 10, Excellent, (489 reviews)
"Very clean room breakfast was good"
michael
The price is HK$761
HK$861 total
includes taxes & fees
23 Aug - 24 Aug
15. Tru By Hilton Cape Girardeau
Tru By Hilton Cape GirardeauCape Girardeau
9.6 out of 10, Exceptional, (159 reviews)
"The area and room looks great and clean. The service was excellent"
Luis
The price is HK$701
HK$798 total
includes taxes & fees
9 Aug - 10 Aug
16. Hampton Inn Sikeston
Hampton Inn SikestonSikeston
9.0 out of 10, Wonderful, (600 reviews)
"Staff were great at Check in, room was clean, breakfast was good."
Brandi
The price is HK$822
HK$931 total
includes taxes & fees
20 Aug - 21 Aug
17. Pear Tree Inn Cape Girardeau West
Pear Tree Inn Cape Girardeau WestCape Girardeau
9.0 out of 10, Wonderful, (1,006 reviews)
"This was a very clean motel and had an excellent breakfast! Will stay there again!"
Bonnie
The price is HK$565
HK$637 total
includes taxes & fees
16 Aug - 17 Aug
18. Super 8 by Wyndham Farmington
Super 8 by Wyndham FarmingtonFarmington
8.0 out of 10, Very good, (664 reviews)
"Will stay here when I return"
Sarah
The price is HK$467
HK$508 total
includes taxes & fees
10 Aug - 11 Aug
19. Motel 6 Poplar Bluff, MO
Motel 6 Poplar Bluff, MOPoplar Bluff
8.0 out of 10, Very good, (1,006 reviews)
"We stayed at the Motel 6 in Poplar Bluff as a stopping point on our way to Nashville. It was clean, comfortable, and provided us a convenient place spend the night."
Doug
The price is HK$620
HK$694 total
includes taxes & fees
4 Aug - 5 Aug
20. Fairfield Inn & Suites by Marriott Sikeston
Fairfield Inn & Suites by Marriott SikestonSikeston
9.4 out of 10, Exceptional, (101 reviews)
"Perfect last minute stop on our road trip
Very clean, well maintained and pleasant staff"
Dwain
The price is HK$863
HK$977 total
includes taxes & fees
13 Aug - 14 Aug
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Holiday Rentals in Southeast Missouri
Cabin
Postcard Cabins St Francois, Outdoor Collection by Marriott Bonvoy
Postcard Cabins St Francois, Outdoor Collection by Marriott BonvoyFrench Village
9.8 out of 10, Exceptional, (91 reviews)
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Stay near popular Southeast Missouri attractions
Learn more about Southeast Missouri
Discover the family-friendly area of Southeast Missouri—wineries, a scenic riverfront and sights from Crane Lake Recreation Area to K Bridge Recreation Area.
Photo by Bill Dillard
Open Photo by Bill Dillard
Top Southeast Missouri Hotel Reviews
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