Des Peres 4 Stars Hotels

Start date: Check-in selected.
To Date
End date: Check-out
  • Change your mind

    Book hotels with free cancellation
  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
  • Be picky

    Search almost a million properties worldwide

Check availability on Des Peres 4 Star Hotels

This weekend
Next weekend

Our top choices for Des Peres 4-star hotels

Magnolia Hotel St. Louis, a Tribute Portfolio Hotel

Magnolia Hotel St. Louis, a Tribute Portfolio Hotel
4.0 star property
Downtown St. Louis
8.8 out of 10, Excellent, (1178)
"Great staff and location"
United States
Robin or David
The price is HK$754
HK$897 total
includes taxes & fees
25 Jan - 26 Jan 2026
Magnolia Hotel St. Louis, a Tribute Portfolio Hotel

Hyatt Regency St. Louis at The Arch

Hyatt Regency St. Louis at The Arch
4.0 star property
Downtown St. Louis
8.4 out of 10, Very good, (4043)
"Staff was supper nice and it all went so smooth."
United States
Brayden
The price is HK$1,003
HK$1,182 total
includes taxes & fees
1 Jan - 2 Jan 2026
Hyatt Regency St. Louis at The Arch

Hilton St. Louis Frontenac

Hilton St. Louis Frontenac
4.0 star property
Frontenac
8.8 out of 10, Excellent, (1003)
"Great room, great amenities!"
United States
Linda or James
The price is HK$1,013
HK$1,180 total
includes taxes & fees
11 Jan - 12 Jan 2026
Hilton St. Louis Frontenac

21C Museum Hotel St Louis

21C Museum Hotel St Louis
4.5 star property
Downtown West
9.0 out of 10, Wonderful, (1515)
"Hotel was comfortable, clean and unique. All staff was wonderful "
United States
Sharon
The price is HK$1,112
HK$1,339 total
includes taxes & fees
5 Jan - 6 Jan 2026
21C Museum Hotel St Louis

The Cheshire

The Cheshire
4.0 star property
Richmond Heights
8.6 out of 10, Excellent, (1001)
"Very friendly staff. Clean, comfortable, and a GREAT breakfast!"
United States
Christine
The price is HK$917
HK$1,089 total
includes taxes & fees
18 Jan - 19 Jan 2026
The Cheshire

Renaissance St. Louis Airport Hotel

Renaissance St. Louis Airport Hotel
4.0 star property
Berkeley
8.4 out of 10, Very good, (1064)
"I loved the service, room cleanliness, club lounge offered a nice variety of food and treats. The property is noticeably old but well maintained. "
United States
Ingrid I
The price is HK$948
HK$1,109 total
includes taxes & fees
30 Jan - 31 Jan 2026
Renaissance St. Louis Airport Hotel

Angad Arts Hotel St. Louis, Tapestry Collection by Hilton

Angad Arts Hotel St. Louis, Tapestry Collection by Hilton
4.0 star property
Grand Center
8.8 out of 10, Excellent, (1044)
"Great location and on-site food/beverage"
United States
Jennifer
The price is HK$1,013
HK$1,195 total
includes taxes & fees
3 Jan - 4 Jan 2026
Angad Arts Hotel St. Louis, Tapestry Collection by Hilton

Live by Loews - St.Louis

Live by Loews - St.Louis
4.0 star property
Downtown St. Louis
9.4 out of 10, Exceptional, (1105)
"Clean room, great restaurant and bar down stairs "
United States
Ambria
The price is HK$1,158
HK$1,377 total
includes taxes & fees
1 Jan - 2 Jan 2026
Live by Loews - St.Louis

The Westin St. Louis

The Westin St. Louis
4.5 star property
Downtown St. Louis
8.6 out of 10, Excellent, (1004)
"Great location "
United States
Gregory
The price is HK$1,117
HK$1,306 total
includes taxes & fees
15 Jan - 16 Jan 2026
The Westin St. Louis

Ameristar Casino Resort and Spa

Ameristar Casino Resort and Spa
4.5 star property
St. Charles
8.4 out of 10, Very good, (1011)
"Clean room, wonderful helpful pleasant staff, amenities, everything was great love staying here!"
United States
Robyn
The price is HK$1,392
HK$1,756 total
includes taxes & fees
11 Jan - 12 Jan 2026
Ameristar Casino Resort and Spa

DoubleTree by Hilton St. Louis Forest Park

DoubleTree by Hilton St. Louis Forest Park
4.0 star property
Central West End
8.2 out of 10, Very good, (1004)
"Good breakfast and perfect location. "
United States
Chaquita
The price is HK$950
HK$1,120 total
includes taxes & fees
6 Jan - 7 Jan 2026
DoubleTree by Hilton St. Louis Forest Park

River City Casino & Hotel

River City Casino & Hotel
4.0 star property
St. Louis
9.0 out of 10, Wonderful, (1455)
"Everything was absolutely wonderfull"
United States
Suada
The price is HK$685
HK$911 total
includes taxes & fees
1 Jan - 2 Jan 2026
River City Casino & Hotel

St. Louis Union Station Hotel, Curio Collection by Hilton

St. Louis Union Station Hotel, Curio Collection by Hilton
4.0 star property
Downtown West
8.6 out of 10, Excellent, (1006)
"The hotel itself was just beautiful and grand! Beautifully decorated for the holidays and the amenities and attractions surrounding Union station were perfect for our family of 4! Our room was spacious and clean and we loved our stay! "
United States
Kelly
The price is HK$1,217
HK$1,448 total
includes taxes & fees
22 Jan - 23 Jan 2026
St. Louis Union Station Hotel, Curio Collection by Hilton

Marriott St. Louis Grand

Marriott St. Louis Grand
4.0 star property
Downtown St. Louis
8.2 out of 10, Very good, (1002)
"Great location and always accommodating for early check in. "
United States
Lisa
The price is HK$1,158
HK$1,377 total
includes taxes & fees
1 Jan - 2 Jan 2026
Marriott St. Louis Grand

Moonrise Hotel

Moonrise Hotel
4.0 star property
Delmar Loop
9.0 out of 10, Wonderful, (1923)
"Great place"
United States
Edward
The price is HK$961
HK$1,142 total
includes taxes & fees
1 Jan - 2 Jan 2026
Moonrise Hotel

Marriott St. Louis Airport

Marriott St. Louis Airport
4.0 star property
Edmundson
8.0 out of 10, Very good, (1004)
"The staff were very nice!"
United States
Angela
The price is HK$992
HK$1,183 total
includes taxes & fees
9 Jan - 10 Jan 2026
Marriott St. Louis Airport

Hilton Pennywell St. Louis at the Arch

Hilton Pennywell St. Louis at the Arch
4.0 star property
Downtown St. Louis
8.8 out of 10, Excellent, (1020)
"Staff were real nice. Accommodating. "
United States
Tim
The price is HK$833
HK$982 total
includes taxes & fees
5 Jan - 6 Jan 2026
Hilton Pennywell St. Louis at the Arch

Le Méridien St. Louis Clayton

Le Méridien St. Louis Clayton
4.0 star property
Clayton
8.8 out of 10, Excellent, (681)
"The gym was amazing! "
United States
Hannah
The price is HK$926
HK$1,091 total
includes taxes & fees
1 Jan - 2 Jan 2026
Le Méridien St. Louis Clayton

DoubleTree by Hilton St. Louis - Westport

DoubleTree by Hilton St. Louis - Westport
4.0 star property
Maryland Heights
8.2 out of 10, Very good, (1007)
"Stayed one night felt very safe here"
United States
William
The price is HK$905
HK$1,050 total
includes taxes & fees
9 Jan - 10 Jan 2026
DoubleTree by Hilton St. Louis - Westport

Embassy Suites by Hilton St. Louis Downtown

Embassy Suites by Hilton St. Louis Downtown
4.0 star property
Downtown St. Louis
8.8 out of 10, Excellent, (1260)
"Very cool hotel, rooms were clean and nice design, the food at the bar/restaurant was fantastic!!!"
United States
Cullin
The price is HK$854
HK$1,016 total
includes taxes & fees
5 Jan - 6 Jan 2026
Embassy Suites by Hilton St. Louis Downtown
Save an average of 15% on thousands of hotels when you're signed in

Explore similar 5-star hotels

Many 5-star hotels have the same amenities as 4-star hotels. See all 5-star hotels in Des Peres.
Still don't see what you're looking for?
See all properties in Des Peres.
You can also use these popular filters to refine your search.
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Learn more about Des Peres

Just minutes from St. Louis, this charming suburb offers family-friendly recreation at Sugar Creek Park with playgrounds and walking trails. Spend an afternoon exploring the fascinating Museum of Transport where vintage trains and cars bring America's transit history to life.

Osage Beach Landmark Buildings in the Historic District on the Main Street near the Lake of the Ozarks in Camden and Miller Counties in Missouri, USA

Top Des Peres Hotel Reviews

Frequently asked questions

What are the best 4-star hotels in Des Peres?
If you're seeking upscale comfort and loads of amenities on your Des Peres escape, check out Hilton St. Louis Frontenac. This leading 4-star hotel offers concierge services and beauty services. Le Méridien St. Louis Clayton also gets rave reviews from Expedia customers. Premium bedding and a terrace are among its conveniences.
How much does it cost to stay in a 4-star hotel in Des Peres?
We can help you easily track down the ideal 4-star hotel for your stay in Des Peres. Use our handy filter tool to tailor your search by things like price, amenities and star rating and get access to fantastic deals in a couple of clicks.

  • Search for the lowest price from HK$3,771

What's the difference between 5-star and 4-star hotels in Des Peres?
Treat yourself to refined living during your Des Peres escape by checking in to a 4-star hotel. As well as featuring upmarket accommodation, these properties are typically packed with amenities such as bathrobes, large beds and plenty more. A 5-star hotel will go the extra mile to make your stay an even more lavish and unforgettable one. 24-hour concierge assistance, elegant décor and world-class dining are a few of the superior conveniences and services you'll likely get access to.

Explore a world of travel with Expedia