A coastal cityscape with high-rise buildings, a marina, and a clear blue sky.

Panama City 4 Stars Hotels

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Check availability on Panama City 4 Star Hotels

Tonight
22 Sept - 23 Sept
Tomorrow
23 Sept - 24 Sept
This weekend
25 Sept - 27 Sept
Next weekend
2 Oct - 4 Oct

Our top choices for Panama City 4-star hotels

A spacious lobby with a high ceiling, modern lighting fixtures, and a glass entrance leading to a lower level.
A modern dining area with a wooden table and chairs, a built-in bookshelf, and a decorative hanging light fixture.
A modern bar area with a central island, bar stools, and a television mounted on the ceiling.
A modern restaurant with checkered flooring, wooden chairs, and large windows offering a view of greenery.

1. Crowne Plaza Panama Airport by IHG

Crowne Plaza Panama Airport by IHG
Tocumen Airport
United States
Xenia
HK$957
HK$1,105 total
includes taxes & fees
1 Oct - 2 Oct
Crowne Plaza Panama Airport by IHG
A multi-story building with balconies, arched windows, and decorative railings.
A multi-level atrium with wooden staircases, seating areas, and a decorative ceiling.
A spacious lobby with a wooden staircase, multiple seating areas, and a reception desk.
A rooftop swimming pool with lounge chairs, potted plants, and a view of a city skyline including a prominent building with a dome.

2. Central Hotel Panama Casco Viejo

Central Hotel Panama Casco Viejo
Casco Viejo
United States
Olga
HK$1,492
HK$1,641 total
includes taxes & fees
23 Sept - 24 Sept
Central Hotel Panama Casco Viejo
A hotel room with a large bed, a smaller bed, a sofa, a TV mounted on the wall, and a dining area with a table and chairs.
A reception area with marble reception desks and a sign indicating the reception desk.
A balcony with a view of a swimming pool, palm trees, and city buildings.

3. Hotel El Panama by Faranda Grand, a member of Radisson Individuals

Hotel El Panama by Faranda Grand, a member of Radisson Individuals
Bella Vista
United States
abbigale
HK$787
HK$866 total
includes taxes & fees
27 Sept - 28 Sept
Hotel El Panama by Faranda Grand, a member of Radisson Individuals
A high-rise building with a modern architectural design, featuring a grid of windows and balconies.
A rooftop lounge with modern seating and a panoramic city view.
A rooftop pool area with purple lounge chairs and a city skyline in the background.
A modern spa area with a hot tub, seating, and a city view.

4. Megapolis Hotel Panamá

Megapolis Hotel Panamá
San Francisco
United States
Devika
HK$1,260
HK$1,386 total
includes taxes & fees
23 Sept - 24 Sept
Megapolis Hotel Panamá
A rooftop pool with sun loungers and a city skyline in the background.
A bar area with a curved counter, multiple screens, and a patterned carpet.
A long, narrow hallway with a wooden floor and light-colored walls.
A modern hotel room with a large bed, a desk, a chair, and a wardrobe.

5. Waymore Hotel Spa & Casino

Waymore Hotel Spa & Casino
Bella Vista
United States
Abeke
HK$559
HK$1,046 total
includes taxes & fees
23 Sept - 24 Sept
Waymore Hotel Spa & Casino
A resort with a large swimming pool, thatched-roof structures, and palm trees.
A well-maintained garden with a pathway leading to a gazebo, surrounded by palm trees and a view of the sea.
An outdoor dining area with tables and chairs, overlooking a body of water and a forested island.
A hotel room with a large bed, a chair, a desk, and a view of the ocean.

6. Dreams Playa Bonita Panama - All Inclusive

Dreams Playa Bonita Panama - All Inclusive
Veracruz
United States
Joanna
HK$2,183
HK$2,183 total
includes taxes & fees
1 Oct - 2 Oct
Dreams Playa Bonita Panama - All Inclusive
A buffet with various food items including fruits, juices, and cheeses.
A hotel reception area with a wooden reception desk, seating area with chairs and ottomans, and a large window providing natural light.
A gym with treadmills, weight machines, and dumbbells.
An aerial view of a rectangular swimming pool with two lounge chairs and a ladder.

7. Courtyard by Marriott Panama Metromall

Courtyard by Marriott Panama Metromall
San Antonio
United States
Stephen
HK$794
HK$873 total
includes taxes & fees
9 Oct - 10 Oct
Courtyard by Marriott Panama Metromall
An outdoor patio with wooden tables and beige umbrellas, surrounded by lush greenery and palm trees.
A playground with multiple slides and climbing structures.
A swimming pool with a bridge, surrounded by palm trees and a building with a sloped roof.
A hotel room with two beds, a nightstand with a phone, and a wall-mounted light fixture.

8. Riande Aeropuerto Hotel & Casino

Riande Aeropuerto Hotel & Casino
Tocumen Airport
United States
Tanese
HK$849
HK$934 total
includes taxes & fees
27 Sept - 28 Sept
Riande Aeropuerto Hotel & Casino
A balcony with wicker chairs and a view of the cityscape.
A multi-story hotel with a modern facade, large windows, and a prominent entrance with a covered area.
A reception area with a marble wall, a 'Free Wireless Internet' sign, and a floral arrangement.
A hotel room with a large bed, a desk with a lamp, a chair, and a view of a cityscape through a window.

9. Ramada Plaza by Wyndham Panama Punta Pacifica

Ramada Plaza by Wyndham Panama Punta Pacifica
San Francisco
United States
Maria
HK$771
HK$848 total
includes taxes & fees
5 Oct - 6 Oct
Ramada Plaza by Wyndham Panama Punta Pacifica
A multi-story hotel with a Marriott sign, surrounded by high-rise buildings and a busy street with cars.
A modern reception area with a wooden panel wall, a sign indicating 'Marriott Bonvoy', and three reception desks with digital displays.
A modern cafe with wooden tables and chairs, large windows, and decorative vases on shelves.
A coastal building complex with multiple structures, a prominent tower, and a beach in the foreground.

10. Courtyard by Marriott Panama Multiplaza Mall

Courtyard by Marriott Panama Multiplaza Mall
San Francisco
United States
Holly
HK$925
HK$1,018 total
includes taxes & fees
10 Oct - 11 Oct
Courtyard by Marriott Panama Multiplaza Mall
A modern lobby with a glass railing, a central staircase, and a view of the cityscape through large windows.
A modern living area with a sofa, chairs, and a coffee table. There is a view of the city through large windows.
A modern hotel room with a large window offering a city view, a chandelier, and a cozy seating area.
A spacious lobby with a staircase, seating area, and a bar.

11. Las Americas Golden Tower Panama

Las Americas Golden Tower Panama
San Francisco
United States
Armando
HK$1,192
HK$1,311 total
includes taxes & fees
28 Sept - 29 Sept
Las Americas Golden Tower Panama
A rooftop pool area with lounge chairs and a bar, overlooking a city skyline at sunset.
A buffet setup with various dishes and utensils.
A spacious lobby with high ceilings, large windows, and modern lighting fixtures.
A rooftop terrace with outdoor seating, potted plants, and a view of a hill with buildings in the distance.

12. Marriott Panama Hotel

Marriott Panama Hotel
Panama City
United States
Richard
HK$1,396
HK$1,536 total
includes taxes & fees
2 Oct - 3 Oct
Marriott Panama Hotel
A modern building with a glass facade, a curved structure, and a flat roof.
A modern hotel room with a large bed, a TV, a desk, and a view of the city.
A rooftop lounge area with clear glass tables and chairs, a pool, and potted plants.
A modern hotel room with a large bed, a desk with a flat-screen TV, a city view, and a large painting on the wall.

13. Decapolis Hotel Panama City

Decapolis Hotel Panama City
San Francisco
United States
Jorge Luis
HK$867
HK$954 total
includes taxes & fees
10 Oct - 11 Oct
Decapolis Hotel Panama City
A buffet with various food items and a decorative plant.
A spa area with a hot tub, candles, and a curved bench.
A hotel with a swimming pool, outdoor seating, and a modern architectural design.
A spacious lobby with a high ceiling, a glass railing on the upper level, and a seating area with modern furniture.

14. Sheraton Grand Panama

Sheraton Grand Panama
San Francisco
United States
Noel
HK$1,377
HK$1,514 total
includes taxes & fees
5 Oct - 6 Oct
Sheraton Grand Panama
A resort with a pool area, lounge chairs, and a view of a bridge at night.
A hotel room with a bed, a TV on a wooden cabinet, a nightstand with a lamp, and a view of the outdoors through a glass door.
A bar area with a counter, stools, and a seating area with tables and chairs.
A reception desk with three staff members, a green patterned wall, a wooden reception area, and a large plant.

15. Radisson Hotel Panama Canal

Radisson Hotel Panama Canal
Amador
United Kingdom
Samantha
HK$678
HK$746 total
includes taxes & fees
28 Sept - 29 Sept
Radisson Hotel Panama Canal
A hotel room with a sofa, a coffee table, a TV, and a cabinet.
A hotel room with a large bed, bedside tables with lamps, a chair, and a large window with curtains.
A rooftop swimming pool with lounge chairs and a city skyline in the background.
A cityscape with modern high-rise buildings, including a prominent tower labeled 'TOWERBANK.'

16. Studio Coliving

Studio Coliving
Bella Vista
United States
Phillip
Studio Coliving
A poolside area with covered seating and palm trees.
A modern hotel lobby with a glass facade, seating area with loungers, and a wooden floor.
A modern interior with a large abstract sculpture, a staircase, a sofa with orange cushions, and a patterned rug.
A modern reception area with a large window, a geometric patterned floor, and two potted plants.

17. Sortis Hotel, Spa & Casino, Autograph Collection by Marriott

Sortis Hotel, Spa & Casino, Autograph Collection by Marriott
Bella Vista
United States
Charles
HK$1,561
HK$1,717 total
includes taxes & fees
23 Sept - 24 Sept
Sortis Hotel, Spa & Casino, Autograph Collection by Marriott
A modern hotel entrance with a prominent 'NOVOTEL' sign, large glass windows, and geometric light patterns on the facade.
A spacious lobby with large windows, a curved ceiling, and a seating area with a patterned rug.
A hotel room with a bed and a view of a cityscape through sheer curtains.
A bar area with a variety of liquor bottles, a counter, and seating with tables and chairs.

18. Novotel Panama City

Novotel Panama City
Bella Vista
United States
Philip
HK$678
HK$746 total
includes taxes & fees
18 Oct - 19 Oct
Novotel Panama City
A spacious indoor area with high ceilings, large windows, and multiple dining tables.
A spacious lobby with a tiled floor, large windows, and potted plants.
A white building with multiple balconies, large windows, and decorative railings.
A restaurant with brick walls, arched windows, and a variety of seating arrangements including tables and chairs.

19. American Trade Hotel

American Trade Hotel
Casco Viejo
United States
James
HK$1,406
HK$1,547 total
includes taxes & fees
4 Oct - 5 Oct
American Trade Hotel
A restaurant with multiple dining tables, chairs, and a central water feature.
A historic building with ornate stonework and a balcony with plants.
A modern living room with a sofa, a coffee table, and a TV mounted on the wall.
A bar area with multiple seating options, a bar counter, and a fireplace.

20. Hotel La Compañía Casco Antiguo

Hotel La Compañía Casco Antiguo
Casco Viejo
United States
Reid
HK$2,194
HK$2,413 total
includes taxes & fees
2 Oct - 3 Oct
Hotel La Compañía Casco Antiguo
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Explore similar 5-star hotels

Many 5-star hotels have the same amenities as 4-star hotels. See all 5-star hotels in Panama City.
Hotel Riu Plaza Panama

Hotel Riu Plaza Panama

Calle 50, Urb. Marbella Panama City Panama
HK$1,080
HK$1,188 total
28 Sept - 29 Sept
includes taxes & fees
Hotel Riu Plaza Panama
Waldorf Astoria Panama

Waldorf Astoria Panama

47th St. & Uruguay Street Panama City Panama
HK$2,052
HK$2,257 total
10 Oct - 11 Oct
includes taxes & fees
9/10 Wonderful! (1,000 reviews)
Waldorf Astoria Panama
JW Marriott Panama

JW Marriott Panama

Calle Punta Colon, Punta Pacifica Panama City Panama
HK$2,065
HK$2,271 total
10 Oct - 11 Oct
includes taxes & fees
9.2/10 Wonderful! (1,006 reviews)
JW Marriott Panama
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Learn more about Panama City

The gleaming skyscrapers of this cosmopolitan capital stand in striking contrast to the colonial charm of Casco Viejo. Watch massive ships navigate the Canal locks, then sample ceviche at the seafood market where local fishermen bring their daily catch.

See all hotels in Panama City
A city skyline with high-rise buildings, a calm waterfront, and a sunset sky.

Top Panama City Hotel Reviews

Decapolis Hotel Panama City

Decapolis Hotel Panama City

10/10 Excellent
"Todo fue lindo buen servicio , algo de ensueno, esperamos poder volver"
Roxana 4-night trip
Posted 11 hours ago
Decapolis Hotel Panama City
Hotel El Panama by Faranda Grand, a member of Radisson Individuals

Hotel El Panama by Faranda Grand, a member of Radisson Individuals

10/10 Excellent
"We really enjoyed our stay at Hotel El Panama. The rooms were cleaned every day, and we always had fresh towels. The reception staff were very friendly and helpful whenever we needed anything. We also really enjoyed the breakfast there was such a great variety to choose from. The location was another plus, with lots of stores and restaurants nearby, making it easy to get around. Overall, we had a great experience and would definitely stay here again!"
Kimerly 6-night trip
Posted 12 hours ago
Hotel El Panama by Faranda Grand, a member of Radisson Individuals
Waymore Hotel Spa & Casino

Waymore Hotel Spa & Casino

8/10 Good
"I have known this place when it was Veneto… Many years ago. They have done a great job renovating the hotel, casino and the all building! The ambiance and the spirit hasn’t come back. They had orchestras and bands, today they have karaoke."
Claude 1-night trip
Posted 15 hours ago
Waymore Hotel Spa & Casino
Central Hotel Panama Casco Viejo

Central Hotel Panama Casco Viejo

10/10 Excellent
"Such a great experience! I’d recommend it to anyone and love to stay again."
Joshua 2-night trip
Posted 2 days ago
Central Hotel Panama Casco Viejo

Frequently asked questions

What are the best 4-star hotels in Panama City?
Continental Hotel Panamá is a 4-star hotel in Panama City that's popular among Expedia customers. An art gallery and proposal/romance packages are just a couple of its amenities. Travellers also recommend Hotel El Panama by Faranda Grand, a member of Radisson Individuals. From a swimming pool to a steam room, it offers conveniences that cater to every aspect of your relaxation and entertainment.
How much does it cost to stay in a 4-star hotel in Panama City?
To lock in a 4-star hotel in Panama City that fits your budget, make use of Expedia's handy search filters. Take a look at the availability during your holiday dates and use our pricing filter to set your limit. You can also sort your results by the most affordable escape first.
  • Search for the lowest price from HK$1,188
What's the difference between 5-star and 4-star hotels in Panama City?
Offering a friendly traveller experience and upmarket décor, 4-star hotels are a fantastic option for your Panama City holiday. These types of accommodation generally feature loads of useful amenities that make it a breeze to unpack and unwind — think 24-hour room service, gyms and pools. Or enjoy even more lavishness at a 5-star hotel designed to indulge you in high-end perks and amenities. Concierge assistance, complimentary toiletries and fine dining are typically included at these swanky properties.

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