A red train on tracks, palm trees, and modern buildings.

Central San Diego Holiday Rentals

  • Change your mind

    Book hotels with free cancellation

  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in

  • Be picky

    Search almost a million properties worldwide

Check prices for these dates

In two weeks
4 Sept - 6 Sept
In two months
16 Oct - 18 Oct
In three months
13 Nov - 15 Nov
In four months
11 Dec - 13 Dec

Our top choices for Central San Diego holiday rentals

Lobby sitting area

1. Uptown Inn by Vantaggio - Limited Service Apart-Hotel

Uptown Inn by Vantaggio - Limited Service Apart-Hotel
2.5 star property
Hillcrest
8.4 out of 10, Very good, (436 reviews)
"Staff were wonderful. Great location."
United States
Benjamin
The price is HK$750
HK$845 total
includes taxes & fees
25 Aug - 26 Aug
Uptown Inn by Vantaggio - Limited Service Apart-Hotel
Terrace/patio

2. City24 Hotel Little Italy Mission Hills

City24 Hotel Little Italy Mission Hills
4.5 star property
Middletown
9.6 out of 10, Exceptional, (191 reviews)
"Enjoyed my stay! Clean spacious room and friendly staff."
United States
omokayode
The price is HK$1,047
HK$1,447 total
includes taxes & fees
1 Sept - 2 Sept
City24 Hotel Little Italy Mission Hills
Exterior

3. San Diego Centralized Retreat

San Diego Centralized Retreat
Birdland
10.0 out of 10, Exceptional, (1 review)
"A beautiful apartment! Definitely going to reserve that location for more days next time. Kitchen is great and loved having upstairs-downstairs for separate spaces when one of us was working"
United States
Margaret C.
The price is HK$793
HK$1,887 total
includes taxes & fees
1 Sept - 2 Sept
San Diego Centralized Retreat
Interior

4. Classic Hillcrest Escape – Near University Heights, Balboa Park & Zoo

Classic Hillcrest Escape – Near University Heights, Balboa Park & Zoo
University Heights
10.0 out of 10, Exceptional, (3 reviews)
"The host was great. The location was great. The place was very clean, and had all the basics."
United States
Kevin A.
The price is HK$784
HK$2,980 total
includes taxes & fees
24 Aug - 25 Aug
Classic Hillcrest Escape – Near University Heights, Balboa Park & Zoo
Property grounds

5. Adorable 1 bd cottage, heart of Old Town-- WE LOVE PETS! Insta @oldtownvacay

Adorable 1 bd cottage, heart of Old Town-- WE LOVE PETS! Insta @oldtownvacay
Old Town San Diego
10.0 out of 10, Exceptional, (301 reviews)
"Super cute, private little cottage in a great location. Loved the stay, very easy process and great host!"
United States
Ross
The price is HK$1,235
HK$1,573 total
includes taxes & fees
24 Aug - 25 Aug
Adorable 1 bd cottage, heart of Old Town-- WE LOVE PETS! Insta @oldtownvacay
Property grounds

6. Close to Airport | Walk to Restaurants

Close to Airport | Walk to Restaurants
Middletown
8.8 out of 10, Excellent, (3 reviews)
"Exactly as advertised. Door to bathroom being shutters was an interesting decision but apart from that it was clean and in good condition and generally a good place to stay. Great location, close to a row of restaurants and can see the taxiways for San Diego international."
United States
Yan W.
The price is HK$659
HK$2,600 total
includes taxes & fees
25 Aug - 26 Aug
Close to Airport | Walk to Restaurants
Living area

7. Relaxing Retreat in North Park – 3943

Relaxing Retreat in North Park – 3943
North Park
10.0 out of 10, Exceptional, (1 review)
"The stay and experience there and with the owner was absolutely great. The place was cozy and clean. He was on the spot with all needs that we're needing to be met. "
United States
Jamall D.
The price is HK$669
HK$1,963 total
includes taxes & fees
26 Aug - 27 Aug
Relaxing Retreat in North Park – 3943
Room

8. Luxury San Diego 1BR with Premium Conveniences

Luxury San Diego 1BR with Premium Conveniences
Mid-City
The price is HK$847
HK$2,171 total
includes taxes & fees
15 Sept - 16 Sept
Luxury San Diego 1BR with Premium Conveniences
Terrace/patio

9. Cozy 2-Bedroom Cottage Near Balboa Park

Cozy 2-Bedroom Cottage Near Balboa Park
Mid-City
8.8 out of 10, Excellent, (11 reviews)
"The place was as advertised. Comfortable and good privacy in an area that at first glance, didn’t seem like it would have any"
United States
Steve F.
The price is HK$1,011
HK$2,379 total
includes taxes & fees
31 Aug - 1 Sept
Cozy 2-Bedroom Cottage Near Balboa Park
Property grounds

10. Canyon Hideaway by Coastline Vacation Rentals

Canyon Hideaway by Coastline Vacation Rentals
North Park
10.0 out of 10, Exceptional, (1 review)
"Easy and quiet place to stay. Parking wasn't difficult. It is close to everything but still far enough away that it wasn't busy. "
United States
Maya D.
The price is HK$728
HK$2,218 total
includes taxes & fees
30 Aug - 31 Aug
Canyon Hideaway by Coastline Vacation Rentals
Terrace/patio

11. 1 mile to Gaslamp—eScooters, Hot tub, Sauna

1 mile to Gaslamp—eScooters, Hot tub, Sauna
Golden Hill
10.0 out of 10, Exceptional, (17 reviews)
"We really enjoyed our stay! Place is clean and just so calming with all the fun amenities!! Would certainly come back and stay here any time! Chelsea is very approachable and very nice."
United States
Muhib H.
The price is HK$788
HK$10,058 total
includes taxes & fees
1 Sept - 2 Sept
1 mile to Gaslamp—eScooters, Hot tub, Sauna
Beach

12. Secluded, Charming and Unique! Spacious Apartment EXCELLENT Central Location

Secluded, Charming and Unique! Spacious Apartment EXCELLENT Central Location
Mission Valley
9.2 out of 10, Wonderful, (66 reviews)
"My overall experience was excellent. The place is close by several restaurants and shops. The place was decent stay and spacious enough for 4-5 people. The host communicated outstanding and open to be available with any questions or concerns which was appreciated. "
United States
Michelle A.
The price is HK$1,207
HK$2,927 total
includes taxes & fees
25 Aug - 26 Aug
Secluded, Charming and Unique! Spacious Apartment EXCELLENT Central Location
Beach

13. Adorable 1 bedroom house 8 min from La Jolla!

Adorable 1 bedroom house 8 min from La Jolla!
Bay Ho
10.0 out of 10, Exceptional, (57 reviews)
"Fantastic place and host especially for the price"
United States
Fayaz J.
The price is HK$1,482
HK$2,483 total
includes taxes & fees
26 Aug - 27 Aug
Adorable 1 bedroom house 8 min from La Jolla!
Dining

14. Explore San Diego from a Central Location with Canyon Views

Explore San Diego from a Central Location with Canyon Views
North Park
10.0 out of 10, Exceptional, (5 reviews)
"Check in was nice and easy. Hosts were very responsive and helped out with a small supply issue in minutes. The space was clean and organized and made for a great stay on my work trip."
United States
Corey M.
The price is HK$1,058
HK$2,589 total
includes taxes & fees
9 Sept - 10 Sept
Explore San Diego from a Central Location with Canyon Views
Living area

15. Charming 2 bedroom San Diego home-Close to Downtown/Balboa Park/SeaWorld/Beaches

Charming 2 bedroom San Diego home-Close to Downtown/Balboa Park/SeaWorld/Beaches
Mid-City
8.0 out of 10, Very good, (4 reviews)
"We thoroughly appreciated the communications provided by the host. Initially had a few teething issues, with the keylock code not working, and a smell in the bedroom and the living area, but this was rectified and a cleaning crew came in twice for it. Place is perfectly situated (with car use) but a bit less so if on foot, or public transportation. The laundry in the shed and the kitchen are always welcome especially as our booking was over 2 weeks long! Thanks again for a suitable stay for us!"
United States
Carlo Luis
The price is HK$1,228
HK$4,058 total
includes taxes & fees
23 Aug - 24 Aug
Charming 2 bedroom San Diego home-Close to Downtown/Balboa Park/SeaWorld/Beaches
Room

16. Stylish & Comfy Gem: Walk To Everything ~ Parking!

Stylish & Comfy Gem: Walk To Everything ~ Parking!
North Park
9.0 out of 10, Wonderful, (2 reviews)
"Great stay, very tight parking spot though!"
United States
Alana M.
The price is HK$1,016
HK$2,757 total
includes taxes & fees
25 Aug - 26 Aug
Stylish & Comfy Gem: Walk To Everything ~ Parking!
Living area

17. Upstairs Hillcrest Studio close to Balboa Park

Upstairs Hillcrest Studio close to Balboa Park
University Heights
The price is HK$862
HK$3,077 total
includes taxes & fees
1 Sept - 2 Sept
Upstairs Hillcrest Studio close to Balboa Park
Private kitchen

18. Step Into Style: Walkable Living in South Park

Step Into Style: Walkable Living in South Park
South Park
10.0 out of 10, Exceptional, (2 reviews)
"Great location and great stay."
United States
Steven B.
The price is HK$1,612
HK$3,236 total
includes taxes & fees
2 Sept - 3 Sept
Step Into Style: Walkable Living in South Park
Living area

19. 3 Story Spanish Style House, Best Location in SD. Views of North Park, With AC

3 Story Spanish Style House, Best Location in SD. Views of North Park, With AC
North Park
8.4 out of 10, Very good, (29 reviews)
"Check-in and check-out went smoothly. The location was easy to find and the surrounding area was quiet, allowing for a relaxing stay. Tissues and paper towels were not provided, so I recommend bringing your own."
Japan
t
The price is HK$1,270
HK$2,614 total
includes taxes & fees
24 Aug - 25 Aug
3 Story Spanish Style House, Best Location in SD. Views of North Park, With AC
Living area

20. Charming 2-bedroom apartment in terrific San Diego North Park Area with WiFi

Charming 2-bedroom apartment in terrific San Diego North Park Area with WiFi
North Park
7.4 out of 10, Good, (6 reviews)
"We left something at the home & host contacted us to figure it out."
United States
Blake G.
The price is HK$941
HK$2,240 total
includes taxes & fees
27 Aug - 28 Aug
Charming 2-bedroom apartment in terrific San Diego North Park Area with WiFi
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties
Save an average of 15% on thousands of hotels when you're signed in
Sign in
Sign up, it's free

Top Central San Diego Hotel Reviews

Legacy Resort Hotel & Spa

Legacy Resort Hotel & Spa

8/10 Good
"Stayed three nights here. The area itself is on “Hotel Circle,” so it’s dense with hotels of varying quality — we noticed some police activity next door at the Holiday Inn one night, which isn’t a reflection on Legacy itself, just something worth knowing about the neighborhood. The hotel is centrally located and convenient to a lot of San Diego. The property looks great from the outside, with a convention center attached, and the lobby is large and well-kept. There’s an on-site restaurant, though we didn’t eat there so can’t speak to it. One quirky detail: the two elevators don’t share a call system — pressing the call button for elevator one only summons elevator one, and elevator two won’t come unless you press its button separately. Minor annoyance, not a dealbreaker. The pool and hot tub area was a highlight — the hot tub is large and kept at a great temperature, and the pool/lounge area overall was enjoyable. There’s also a spa on the first floor, though we didn’t use it. The gym, on the other hand, was easily the weakest part of the property: a few treadmills, a sit-up bench, and some weighted balls, but zero free weights, no benches. Not usable for any real strength training. It didn’t affect our trip since we weren’t planning to work out, but worth flagging for anyone who is. Rooms were a comfortable, mid-sized layout. Cleanliness was good — no hair in the bed or shower, which we always check for. The carpet showed some wear (a bit rumpled, faint stains) but nothin"
McKay 3-night trip
Posted 2 hours ago
Legacy Resort Hotel & Spa

Find out more about Central San Diego

Search for holiday rentals in Central San Diego on Expedia! You can easily find your home rentals, villas, holiday apartments in Central San Diego using one of the methods below:

  • View our selection of featured holiday rentals in Central San Diego
  • Use the map to find apartments and other holiday homes in the Central San Diego neighbourhood you prefer
  • Enter your travel dates to view the best deals on holiday rentals in Central San Diego while they last

Look no further and take a look at our great range of rental properties in Central San Diego!

Explore a world of travel with Expedia