An aerial view of a city with a prominent building featuring a golden dome and green-topped towers.

Search Vacation Homes in Des Moines

  • Change your mind

    Book hotels with free cancellation

  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in

  • Be picky

    Search almost a million properties worldwide

Check prices for these dates

In two weeks
21 Aug - 23 Aug
In two months
2 Oct - 4 Oct
In three months
30 Oct - 1 Nov
In four months
27 Nov - 29 Nov

Our top choices for Des Moines holiday homes

Exterior

1. Spacious 5BR Retreat w Game Room, Huge Drive & Private Setting

Spacious 5BR Retreat w Game Room, Huge Drive & Private Setting
Saylorville
10.0 out of 10, Exceptional, (1 review)
"It was great"
United States
Jace G.
The price is HK$1,594
HK$4,553 total
includes taxes & fees
25 Aug - 26 Aug
Spacious 5BR Retreat w Game Room, Huge Drive & Private Setting
Terrace/patio

2. Downtown Skyline Views in Modern Townhome with Rooftop Patios

Downtown Skyline Views in Modern Townhome with Rooftop Patios
Downtown Des Moines
10.0 out of 10, Exceptional, (63 reviews)
"We had a wonderful stay. Great location!"
United States
Julie J.
The price is HK$1,334
HK$2,373 total
includes taxes & fees
10 Aug - 11 Aug
Downtown Skyline Views in Modern Townhome with Rooftop Patios
Pool

3. Studio Suite w/ Jetted Tub | Free Breakfast!

Studio Suite w/ Jetted Tub | Free Breakfast!
West Des Moines
The price is HK$910
HK$1,195 total
includes taxes & fees
23 Aug - 24 Aug
Studio Suite w/ Jetted Tub | Free Breakfast!
Smart TV, fireplace, video games, ping pong

4. SO MUCH FUN! ARCADE, PL TBL, PNG PNG, YARD GAMES, INDOOR AND OUTDOOR POOLS!!

SO MUCH FUN! ARCADE, PL TBL, PNG PNG, YARD GAMES, INDOOR AND OUTDOOR POOLS!!
Woodland Heights
9.6 out of 10, Exceptional, (88 reviews)
"It was a great property! We would highly recommend to any larger groups looking for a place to stay. The rooms and kitchen were clean and we had all of the details needed for a successful stay!"
United States
Ethan H.
The price is HK$2,345
HK$5,762 total
includes taxes & fees
26 Aug - 27 Aug
SO MUCH FUN! ARCADE, PL TBL, PNG PNG, YARD GAMES, INDOOR AND OUTDOOR POOLS!!
Interior

5. A Private Boho-Modern Stay Minutes to Downtown w/ KING Bed and Hidden Nook!

A Private Boho-Modern Stay Minutes to Downtown w/ KING Bed and Hidden Nook!
Indianola Hills
10.0 out of 10, Exceptional, (17 reviews)
"Everything was great!"
United States
Dan A.
The price is HK$824
HK$1,713 total
includes taxes & fees
10 Aug - 11 Aug
A Private Boho-Modern Stay Minutes to Downtown w/ KING Bed and Hidden Nook!
TV

6. Entire Bungalow with Fenced-In Yard! Sleeps 6 & Pet-Friendly, Central Des Moines

Entire Bungalow with Fenced-In Yard! Sleeps 6 & Pet-Friendly, Central Des Moines
Des Moines
10.0 out of 10, Exceptional, (28 reviews)
"Everything was so clean, entry was super easy and straightforward. The location was great and we’d absolutely stay here again!"
United States
Sierra F.
The price is HK$932
HK$1,439 total
includes taxes & fees
17 Aug - 18 Aug
Entire Bungalow with Fenced-In Yard! Sleeps 6 & Pet-Friendly, Central Des Moines
Coffee/tea maker, fridge, microwave, oven

7. A Charming Home Minutes to Downtown, Zoo, & Airport with Hidden Reading Nook!

A Charming Home Minutes to Downtown, Zoo, & Airport with Hidden Reading Nook!
Indianola Hills
10.0 out of 10, Exceptional, (29 reviews)
"Great place!"
United States
Kenneth M.
The price is HK$863
HK$1,757 total
includes taxes & fees
10 Aug - 11 Aug
A Charming Home Minutes to Downtown, Zoo, & Airport with Hidden Reading Nook!
Outdoor dining

8. The Cow Tipper: Near Everything - SPA - Game Room - Fire Pit & Patio - Sleeps 10

The Cow Tipper: Near Everything - SPA - Game Room - Fire Pit & Patio - Sleeps 10
Woodland Heights
10.0 out of 10, Exceptional, (74 reviews)
"This was a charming house with space for our group of 6. Very clean throughout with comfortable beds. The location made getting around easy."
United States
Chris M.
The price is HK$969
HK$2,693 total
includes taxes & fees
31 Aug - 1 Sept
The Cow Tipper: Near Everything - SPA - Game Room - Fire Pit & Patio - Sleeps 10
Smart TV

9. The Vintage Haven. A cozy home 5 mins from Downtown Des Moines. Pet-Friendly

The Vintage Haven. A cozy home 5 mins from Downtown Des Moines. Pet-Friendly
Des Moines
9.6 out of 10, Exceptional, (38 reviews)
"The house was beautifully decorated and great for our family outing. The beds were comfortable and the location was great!"
United States
Trista K.
The price is HK$1,405
HK$2,601 total
includes taxes & fees
19 Aug - 20 Aug
The Vintage Haven. A cozy home 5 mins from Downtown Des Moines. Pet-Friendly
Exterior

10. Amazing Location~Fenced In~Great Patio~ Fire Pit

Amazing Location~Fenced In~Great Patio~ Fire Pit
Woodland Heights
The price is HK$1,765
HK$3,769 total
includes taxes & fees
31 Aug - 1 Sept
Amazing Location~Fenced In~Great Patio~ Fire Pit
Outdoor spa tub

11. The CORN CRIB: Spa - Game Room - BBQ - Office - DOWNTOWN - Sleeps 14

The CORN CRIB: Spa - Game Room - BBQ - Office - DOWNTOWN - Sleeps 14
Drake
10.0 out of 10, Exceptional, (29 reviews)
"Cute, clean, well-kept home. Nice backyard for gathering.Was great for our large group. Downtown, so close to where we needed to be."
United States
Virginia U.
The price is HK$1,042
HK$2,889 total
includes taxes & fees
1 Sept - 2 Sept
The CORN CRIB: Spa - Game Room - BBQ - Office - DOWNTOWN - Sleeps 14
Exterior

12. • Casa Dean sleeps 20 close to Fairgrounds and Downtown Des Moines •

• Casa Dean sleeps 20 close to Fairgrounds and Downtown Des Moines •
Des Moines
9.6 out of 10, Exceptional, (29 reviews)
"Multiple rooms set ups with 3 bathrooms made this great for our family to stay. "
United States
R G.
The price is HK$2,647
HK$5,398 total
includes taxes & fees
9 Aug - 10 Aug
• Casa Dean sleeps 20 close to Fairgrounds and Downtown Des Moines •
Interior

13. Fairground Oasis Read~Relax~Rejuvinate

Fairground Oasis Read~Relax~Rejuvinate
Fairground
10.0 out of 10, Exceptional, (1 review)
"The home is exactly as pictured. The small touches like an extra toothbrush or razor, makeup wipes were an added bonus. Nicole was a great communicator and was quick with responses. The back screened in porch was a great quiet spoke to enjoy a cup of coffee or a book. We enjoyed our stay."
United States
Michelle M.
The price is HK$2,588
HK$4,322 total
includes taxes & fees
4 Sept - 5 Sept
Fairground Oasis Read~Relax~Rejuvinate
Smart TV, video games, DVD player, stereo

14. Blending Luxury with Historic Elegance Steps from Downtown

Blending Luxury with Historic Elegance Steps from Downtown
Downtown Des Moines
9.8 out of 10, Exceptional, (10 reviews)
"We loved the house and all the gathering spaces. "
United States
Pat L.
The price is HK$1,128
HK$3,336 total
includes taxes & fees
1 Sept - 2 Sept
Blending Luxury with Historic Elegance Steps from Downtown
Smart TV, books

15. Modern Boho Townhome w/Hidden Reading Nook Near Downtown Des Moines!

Modern Boho Townhome w/Hidden Reading Nook Near Downtown Des Moines!
Des Moines
10.0 out of 10, Exceptional, (4 reviews)
"Such a cute townhouse and was perfect for our weekend away! The reading nook was so cozy. "
United States
Kylie F.
Modern Boho Townhome w/Hidden Reading Nook Near Downtown Des Moines!
Property grounds

16. "The Hay Loft" - Hot Tub - Game Room - Fire Pit - Office - Family FUN

"The Hay Loft" - Hot Tub - Game Room - Fire Pit - Office - Family FUN
Drake
10.0 out of 10, Exceptional, (23 reviews)
"Fantastic location and amenities for the prefect drake relays trip!"
United States
Sean G.
The price is HK$1,713
HK$3,631 total
includes taxes & fees
24 Aug - 25 Aug
"The Hay Loft" - Hot Tub - Game Room - Fire Pit - Office - Family FUN
Microwave, oven, stovetop, dishwasher

17. Charming 3-bedroom ADU in delightful Des Moines with WiFi, AC

Charming 3-bedroom ADU in delightful Des Moines with WiFi, AC
Columbus Park
8.8 out of 10, Excellent, (10 reviews)
"This place was awesome and close the the Iowa fairgrounds. We enjoyed our stay! "
United States
Jessica G.
The price is HK$1,051
HK$2,855 total
includes taxes & fees
4 Sept - 5 Sept
Charming 3-bedroom ADU in delightful Des Moines with WiFi, AC
Interior

18. The Cozy Cottage - Entire house in Des Moines

The Cozy Cottage - Entire house in Des Moines
Greater South Side
9.0 out of 10, Wonderful, (13 reviews)
"Great house!"
United States
Tracy H.
The Cozy Cottage - Entire house in Des Moines
7 bedrooms, desk, free WiFi, bed sheets

19. Beautiful remodeled historic Drake Univ home minutes from downtown and all metro

Beautiful remodeled historic Drake Univ home minutes from downtown and all metro
Drake
10.0 out of 10, Exceptional, (63 reviews)
"Great for a big group. Good communication with host!"
United States
Emily Z.
Beautiful remodeled historic Drake Univ home minutes from downtown and all metro
2 bedrooms, WiFi, bed sheets

20. The Iowa Fair House - Games + Walk to Main Gate

The Iowa Fair House - Games + Walk to Main Gate
Fairground
10.0 out of 10, Exceptional, (5 reviews)
"Rooms clean. Location great! Host was easy to communicate with and very friendly!"
United States
Lily T.
The price is HK$1,569
HK$3,048 total
includes taxes & fees
24 Aug - 25 Aug
The Iowa Fair House - Games + Walk to Main Gate
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties
Save an average of 15% on thousands of hotels when you're signed in
Sign in
Sign up, it's free

Top Des Moines Hotel Reviews

Motel 6 West Des Moines, IA

Motel 6 West Des Moines, IA

8/10 Good
"Rooms were clean. Staff appeared to be busy doing other things. They would help but I needed to ask."
Janelle 2-night trip
Posted 1 hour ago
Motel 6 West Des Moines, IA

Find out more about Des Moines

Des Moines Vacation Homes information

Number of reviews
496
Accommodation
230 Vacation Homes
Lowest Price
HK$1,195
Highest Price
HK$7,529

Explore a world of travel with Expedia