Drive on Holidays Car Hire in South San Diego
Photo by Elizabeth Bagnas
Change your mindPenalty-free cancellation on many/select car hire
Treat yourselfMembers save 10% or more on over 1 million car hire
Shop smartCompare car suppliers to unlock big savings
Explore a world of travel with Expedia
- B&B in Bayfront - E St. Trolley Station
- Vagabond Inn Hotels in Chula Vista
- Casino Hotel Hotels in South Bay
- Hotels near Hotel del Coronado
- 5 Star Hotels in Bonita
- Otay Mesa Hotels
- Hilton Hotels in Imperial Beach
- Beach Hotel Hotels in Chula Vista
- Casino Hotel Hotels in Chula Vista
- Hotels near North Island Credit Union Amphitheatre
- Cheap Hotels in South San Diego
- Chula Vista Hotels
- Hotels near Border Field State Park
- Condo Rentals in South Bay
- Bartell Hotels in National City
- Bonita Hotels
- Bar Hotel Hotels in Chula Vista
- Hotels near Kaiser Permanente Otay Mesa Medical Offices
- B&B in Bonita
- Motel 6 Hotels in National City
- San Ysidro Hotels
- Hostelling International Hotels in Otay Mesa West
- La Quinta Inn & Suites Hotels in Otay Mesa West
- Casino Hotel Hotels in San Ysidro
- Resorts in San Ysidro
- Aparthotels in South San Diego
- Golf Hotel Hotels in Otay
- Condo Rentals in Iris Avenue Trolley Station
- Marriott Hotels & Resorts in San Ysidro
- Villas in San Diego Coast
- 5 Star Hotels in Chula Vista
- Otay Hotels
- Ksl Resorts in Chula Vista
- Ocean View Hills Hotels
- Motels in Encanto - 62nd St Trolley Station
- Hotels near San Diego Bay
- La Quinta Inn & Suites Hotels in Chula Vista
- Guest Houses in San Ysidro
- Condo Rentals in Gaslamp Quarter Station
- Luxury Hotel Hotels in San Ysidro
- Apartments in South Bay
- B&B in 12th and Imperial Transit Center Station
- Residences in South Bay
- Motel 6 Hotels in Chula Vista
- Cheap Hotels in Chula Vista
- B&B in National City
- Hotels near Naval Base San Diego
- Lincoln Park Hotels
- Luxury Hotel Hotels in Chula Vista
- Beach Hotel Hotels in South Bay
- Spa Hotel Hotels in South Bay
- Guest Houses in San Ysidro Transit Center Station
- Cheap Hotels in San Ysidro
- Cabin Rentals in Chula Vista
- Hostels in Chula Vista
- Hotels near Petco Park
- Lgbt Welcoming Hotel Hotels in Otay Mesa
- La Quinta Inn & Suites Hotels in Otay
- Best Western Hotels in Chula Vista
- Villas in South Bay
- Aparthotels in Chula Vista
- Bar Hotel Hotels in South Bay
- Spa Hotel Hotels in Chula Vista
- Flights from Hong Kong (HKG) to San Diego (SDM)
- Flights from Ensenada (ESE) to San Diego (SDM)
- Flights from South Bay
- Flights from Los Angeles (LAX) to San Diego (SDM)
- Flights from San Francisco (SFO) to San Diego (SDM)
- Flights from Victoria (YYJ) to San Diego (SDM)
- Flights from San Ysidro
- Flights from Brown Field Municipal
- Flights from Orange County (SNA) to San Diego (SDM)
- Flights from Coronado
- Flights from Bagdad (BGT) to San Diego (SDM)
- Flights from Chula Vista
- Flights from Bonita
- Flights from Atlanta (ATL) to San Diego (SDM)
Heading to South San Diego? Explore South San Diego with Expedia's Travel Guides to find the best hotels, holiday packages, car hire deals and more!