East Prairie

Travel Guide

A tree-lined landscape with a river and fields.
Drury Inn & Suites Sikeston, MO

Drury Inn & Suites Sikeston, MO

3 out of 5
2608 East Malone Ave, Miner Sikeston MO
Fully refundableReserve now, pay when you stay
The price is HK$871 per night from 13 Aug to 14 Aug
HK$871
HK$1,001 total
13 Aug - 14 Aug
includes taxes & fees
Stay at this business-friendly hotel in Sikeston. Enjoy free breakfast, free Wi-Fi and free parking. Our guests praise the breakfast and the helpful staff in ...
Drury Inn & Suites Sikeston, MO
Days Inn and Suites by Wyndham Sikeston

Days Inn and Suites by Wyndham Sikeston

2 out of 5
220 S Interstate Dr Sikeston MO
The price is HK$500 per night from 3 Sept to 4 Sept
HK$500
HK$570 total
3 Sept - 4 Sept
includes taxes & fees
Stay at this business-friendly hotel in Sikeston. Enjoy free breakfast, free Wi-Fi and free parking. Our guests praise the helpful staff and the clean rooms ...
7.2/10 Good! (1,013 reviews)
"Was a very clean, quiet place to stay. My only complaint was the breakfast was disappointing. They only offered cereal or waffles. Being diabetic I couldn't have either 😥. Yogurt, fruit, eggs/bacon/sausage would be good options. The staff was very nice and helpful."

Reviewed on 9 Aug 2026

Days Inn and Suites by Wyndham Sikeston
Holiday Inn Express & Suites Sikeston Southwest by IHG

Holiday Inn Express & Suites Sikeston Southwest by IHG

2.5 out of 5
115 Hospitality Dr Sikeston MO
The price is HK$761 per night from 23 Aug to 24 Aug
HK$761
HK$862 total
23 Aug - 24 Aug
includes taxes & fees
Stay at this business-friendly hotel in Sikeston. Enjoy free breakfast, free Wi-Fi and free parking. Our guests praise the helpful staff and the clean rooms ...
8.8/10 Excellent! (494 reviews)
"Staff was super nice, giving us more than plenty towels upon request as I mentioned reviews found the suite was only equipped with towels for 2. A convenient and cozy place to stay for a night. Adequate hot breakfast. Gym is small with only bikes, treadmills and weights. The A/C on the wall in the ..."

Reviewed on 9 Aug 2026

Holiday Inn Express & Suites Sikeston Southwest by IHG
See all 87 properties in East Prairie
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Duck Hunting, Fishing or Relaxing Family Vacation

Duck Hunting, Fishing or Relaxing Family Vacation

Hornbeak TN
Stay at this holiday home in Hornbeak. Enjoy a garden, laundry facilities and patios. Popular attractions Willow Towhead and Rat Island are located nearby.
10/10 Exceptional! (241 reviews)
"We booked this for a quiet getaway. Everything was exactly as described and more. The kitchen was fully stocked with everything we needed except the groceries. We loved the dock, my husband even caught a few catfish. We only stayed 3 nights but will definitely be coming back for a longer stay."

Reviewed on 2 Aug 2026

Duck Hunting, Fishing or Relaxing Family Vacation
3 bedroom house on Reelfoot Lake, perfect for families, fisherman and hunters

3 bedroom house on Reelfoot Lake, perfect for families, fisherman and hunters

Hornbeak TN
Stay at this holiday home in Hornbeak. Enjoy free Wi-Fi, laundry facilities and patios. Popular attractions Willow Towhead and Rat Island are located ...
10/10 Exceptional! (11 reviews)
"Great place to stay"

Reviewed on 27 Jul 2026

3 bedroom house on Reelfoot Lake, perfect for families, fisherman and hunters
Come and relax at the Refuge at beautiful Reelfoot Lake!

Come and relax at the Refuge at beautiful Reelfoot Lake!

Hornbeak TN
Enjoy free Wi-Fi, laundry facilities and patios. Popular attractions Willow Towhead and Rat Island are located nearby.
9.4/10 Exceptional! (36 reviews)
"Real foot refuge was a really nice place to stay , and they were really nice to work withWe are in Missouri, family.We had a really great time and wanting to do this again the neighbors were awesome, very friendly in kind.The real foot like visiting center.The pontoon ride was a very great experience.We ..."

Reviewed on 4 Jul 2026

Come and relax at the Refuge at beautiful Reelfoot Lake!
See all properties in East Prairie
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Stay near popular East Prairie attractions

Big Oak Tree State Park

8.0/10 (20 reviews)
You can take time to visit Big Oak Tree State Park during your travels to East Prairie. While you're in the area, wander around the parks.
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