East Prairie

Travel Guide

Drury Inn & Suites Sikeston, MO

Drury Inn & Suites Sikeston, MO

3 out of 5
2608 East Malone Ave, Miner Sikeston MO
The price is HK$700 per night from 29 Dec to 30 Dec
HK$700
HK$805 total
29 Dec - 30 Dec
includes taxes & fees
Stay at this business-friendly hotel in Sikeston. Enjoy free breakfast, free Wi-Fi and free parking. Our guests praise the breakfast and the helpful staff in ...
9.4/10 Exceptional! (1,008 reviews)
This our favorite place to stop for a good night sleep.

Reviewed on 22 Dec 2025

Drury Inn & Suites Sikeston, MO
Hampton Inn Sikeston

Hampton Inn Sikeston

2.5 out of 5
1240 Commerce Drive Sikeston MO
The price is HK$759 per night from 4 Jan to 5 Jan
HK$759
HK$859 total
4 Jan - 5 Jan 2026
includes taxes & fees
Stay at this hotel in Sikeston. Enjoy free breakfast, free Wi-Fi and free parking. Our guests praise the helpful staff in their reviews. Popular attractions ...
8.8/10 Excellent! (449 reviews)
Everything we just lovely

Reviewed on 20 Dec 2025

Hampton Inn Sikeston
Best Western Plus Sikeston

Best Western Plus Sikeston

2.5 out of 5
120 S Interstate Drive Sikeston MO
The price is HK$588 per night from 29 Dec to 30 Dec
HK$588
HK$670 total
29 Dec - 30 Dec
includes taxes & fees
Stay at this hotel in Sikeston. Enjoy free breakfast, free parking and a fitness centre. Our guests praise the breakfast and the helpful staff in their reviews. ...
8.2/10 Very Good! (1,003 reviews)
Barbara and other staff were very friendly. Room was clean .

Reviewed on 16 Dec 2025

Best Western Plus Sikeston
See all 86 properties in East Prairie
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
3 bedroom house on Reelfoot Lake, perfect for families, fisherman and hunters

3 bedroom house on Reelfoot Lake, perfect for families, fisherman and hunters

2 out of 5
Hornbeak TN
Stay at this holiday home in Hornbeak. Enjoy laundry facilities. Popular attractions Willow Towhead and Rat Island are located nearby.
The house was exaclty what we needed. It had everything we needed. We will be back. Great set up for a large group.

Reviewed on 7 Dec 2025

3 bedroom house on Reelfoot Lake, perfect for families, fisherman and hunters
Log Cabin.

Log Cabin.

Hornbeak TN
Stay at this cabin in Hornbeak. Enjoy free Wi-Fi, laundry facilities and patios. Popular attractions Lake Isom National Wildlife Refuge and Willow Towhead are ...
9/10 Wonderful! (32 reviews)
The cabin is beautiful! Had no issues at all. Slept all 14 of us easily and could have slept more. The pond was the kids favorite, loved fishing out of it.

Reviewed on 2 Sept 2025

Log Cabin.
Come and relax at the Refuge at beautiful Reelfoot Lake!

Come and relax at the Refuge at beautiful Reelfoot Lake!

Hornbeak TN
Enjoy free Wi-Fi, laundry facilities and patios. Popular attractions Willow Towhead and Rat Island are located nearby.
9.2/10 Wonderful! (23 reviews)
Great place

Reviewed on 11 Dec 2025

Come and relax at the Refuge at beautiful Reelfoot Lake!
See all properties in East Prairie
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Popular places to visit

Big Oak Tree State Park

You can take time to visit Big Oak Tree State Park during your travels to East Prairie. While you're in the area, wander around the parks.

Big Oak Tree State Park

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