East Prairie

Travel Guide

The Mississippi River near Hannibal, Missouri, USA
Drury Inn & Suites Sikeston, MO

Drury Inn & Suites Sikeston, MO

3 out of 5
2608 East Malone Ave, Miner Sikeston MO
The price is HK$736 per night from 29 Mar to 30 Mar
HK$736
HK$846 total
29 Mar - 30 Mar
includes taxes & fees
Stay at this business-friendly hotel in Sikeston. Enjoy free breakfast, free Wi-Fi and free parking. Our guests praise the breakfast and the helpful staff in ...
9.4/10 Exceptional! (1,000 reviews)
Bedding needs to be updated. Pillows smelled and carpet could be cleaned. Bathroom was clean. Staff was friendly and helpful.

Reviewed on 24 Mar 2026

Drury Inn & Suites Sikeston, MO
Hampton Inn Sikeston

Hampton Inn Sikeston

2.5 out of 5
1240 Commerce Drive Sikeston MO
The price is HK$761 per night from 2 Apr to 3 Apr
HK$761
HK$862 total
2 Apr - 3 Apr
includes taxes & fees
Stay at this hotel in Sikeston. Enjoy free breakfast, free Wi-Fi and free parking. Our guests praise the helpful staff in their reviews. Popular attractions ...
9/10 Wonderful! (513 reviews)
Very nice and helpful staff

Reviewed on 22 Mar 2026

Hampton Inn Sikeston
Best Western Plus Sikeston I-55

Best Western Plus Sikeston I-55

2.5 out of 5
120 S Interstate Drive Sikeston MO
The price is HK$725 per night from 30 Mar to 31 Mar
HK$725
HK$827 total
30 Mar - 31 Mar
includes taxes & fees
Stay at this hotel in Sikeston. Enjoy free breakfast, free parking and a fitness centre. Our guests praise the breakfast and the helpful staff in their reviews. ...
8.4/10 Very Good! (1,001 reviews)
Breakfast selection was fresh but not overwhelming in quality.

Reviewed on 23 Mar 2026

Best Western Plus Sikeston I-55
See all 86 properties in East Prairie
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Duck Hunting, Fishing or Relaxing Family Vacation

Duck Hunting, Fishing or Relaxing Family Vacation

Hornbeak TN
Stay at this holiday home in Hornbeak. Enjoy a garden, laundry facilities and patios. Popular attractions Willow Towhead and Rat Island are located nearby.
10/10 Exceptional! (226 reviews)
The best stocked house we’ve ever stayed at while fishing Reelfoot!!! Highly recommend and will certainly book again!!!

Reviewed on 20 Mar 2026

Duck Hunting, Fishing or Relaxing Family Vacation
Come and relax at the Refuge at beautiful Reelfoot Lake!

Come and relax at the Refuge at beautiful Reelfoot Lake!

Hornbeak TN
Enjoy free Wi-Fi, laundry facilities and patios. Popular attractions Willow Towhead and Rat Island are located nearby.
9.4/10 Exceptional! (26 reviews)
Everything was great

Reviewed on 15 Feb 2026

Come and relax at the Refuge at beautiful Reelfoot Lake!
Beautiful Reelfoot Lake

Beautiful Reelfoot Lake

Tiptonville TN
Stay at this holiday home in Tiptonville. Enjoy free Wi-Fi, a garden and laundry facilities. Popular attractions Campbell's Point and Reelfoot Lake State Park ...
10/10 Exceptional! (98 reviews)
Very warm nice beautiful home. Will for sure use to stay again. Thank you Chris for everything.

Reviewed on 22 Mar 2026

Beautiful Reelfoot Lake
See all properties in East Prairie
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Popular places to visit

Big Oak Tree State Park

You can take time to visit Big Oak Tree State Park during your travels to East Prairie. While you're in the area, wander around the parks.

Big Oak Tree State Park

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