East Prairie

Travel Guide

The Mississippi River near Hannibal, Missouri, USA
Drury Inn & Suites Sikeston, MO

Drury Inn & Suites Sikeston, MO

3 out of 5
2608 East Malone Ave, Miner Sikeston MO
Fully refundableReserve now, pay when you stay
The price is HK$799 per night from 14 May to 15 May
HK$799
HK$918 total
14 May - 15 May
includes taxes & fees
Stay at this business-friendly hotel in Sikeston. Enjoy free breakfast, free Wi-Fi and free parking. Our guests praise the breakfast and the helpful staff in ...
9.6/10 Exceptional! (1,013 reviews)
Breakfast was good

Reviewed on 9 May 2026

Drury Inn & Suites Sikeston, MO
Hampton Inn Sikeston

Hampton Inn Sikeston

2.5 out of 5
1240 Commerce Drive Sikeston MO
The price is HK$796 per night from 17 May to 18 May
HK$796
HK$901 total
17 May - 18 May
includes taxes & fees
Stay at this hotel in Sikeston. Enjoy free breakfast, free Wi-Fi and free parking. Our guests praise the helpful staff in their reviews. Popular attractions ...
9/10 Wonderful! (557 reviews)
Everything was good

Reviewed on 10 May 2026

Hampton Inn Sikeston
Best Western Plus Sikeston I-55

Best Western Plus Sikeston I-55

2.5 out of 5
120 S Interstate Drive Sikeston MO
The price is HK$640 per night from 17 May to 18 May
HK$640
HK$730 total
17 May - 18 May
includes taxes & fees
Stay at this hotel in Sikeston. Enjoy free breakfast, free parking and a fitness centre. Our guests praise the breakfast and the helpful staff in their reviews. ...
8.4/10 Very Good! (1,003 reviews)
Clean. Friendly staff. Great breakfast! The property is older. Stains in the bathtub, noisy air conditioner, worn out mattress. Okay for a one night stay.

Reviewed on 9 May 2026

Best Western Plus Sikeston I-55
See all 89 properties in East Prairie
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
3 bedroom house on Reelfoot Lake, perfect for families, fisherman and hunters

3 bedroom house on Reelfoot Lake, perfect for families, fisherman and hunters

Hornbeak TN
Stay at this holiday home in Hornbeak. Enjoy free Wi-Fi, laundry facilities and patios. Popular attractions Willow Towhead and Rat Island are located ...
10/10 Exceptional! (8 reviews)
We had the best weekend ! Jessica was so friendly , and we loved seeing her pup ! We will definitely be back .

Reviewed on 5 May 2026

3 bedroom house on Reelfoot Lake, perfect for families, fisherman and hunters
Come and relax at the Refuge at beautiful Reelfoot Lake!

Come and relax at the Refuge at beautiful Reelfoot Lake!

Hornbeak TN
Enjoy free Wi-Fi, laundry facilities and patios. Popular attractions Willow Towhead and Rat Island are located nearby.
9.4/10 Exceptional! (28 reviews)
Everything was just what we needed. Perfect weekend

Reviewed on 27 Mar 2026

Come and relax at the Refuge at beautiful Reelfoot Lake!
Fish cleaning station, screened porch, covered front porch, fire pit, 3 BR

Fish cleaning station, screened porch, covered front porch, fire pit, 3 BR

Hornbeak TN
Enjoy free Wi-Fi, laundry facilities and patios. Popular attractions Willow Towhead and Rat Island are located nearby.
9.8/10 Exceptional! (59 reviews)
This place had everything we needed and more. Fully equipped kitchen, with high quality kitchen supplies and plenty of everything. Plenty of towels, wash cloths and hand towels. Water pressure is wonderful. Water is hot hot. Which i love! Elizabeth was so responsive for checking in and out. 10 out ...

Reviewed on 26 Apr 2026

Fish cleaning station, screened porch, covered front porch, fire pit, 3 BR
See all properties in East Prairie
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Popular places to visit

Big Oak Tree State Park

You can take time to visit Big Oak Tree State Park during your travels to East Prairie. While you're in the area, wander around the parks.

Big Oak Tree State Park

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