Default HTG hotel image

Panama City El Machetazo Santa Ana Hotels

  • Change your mind

    Book hotels with free cancellation
  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
  • Be picky

    Search almost a million properties worldwide

Check prices for these dates

This weekend
Next weekend

Filter by

Property class

Guest rating

Selecting then applying a filter from this group will update the results on a new page

Our top choices for El Machetazo Santa Ana hotels

1. La Isabela Suites

La Isabela Suites
3.5 star property
San Felipe, 0.3 km from El Machetazo Santa Ana
10.0 out of 10, Exceptional, (213 reviews)
"Location in old town, across from Plaza Simon Bolivar, is the perfect place to venture around old town and the new city. Great restaurants and shops within easy walking distance. I relied on recommendations from the staff for a couple of things and their selections exceeded my expectations. Highly recommend staying if visiting Panama City."
United States
David
The price is HK$1,165
HK$1,281 total
includes taxes & fees
1 Dec - 2 Dec
La Isabela Suites

2. Sofitel Legend Casco Viejo, Panama City

Sofitel Legend Casco Viejo, Panama City
5.0 star property
San Felipe, 0.8 km from El Machetazo Santa Ana
9.8 out of 10, Exceptional, (771 reviews)
"Magnificent property. Location. Staff. Quality of all, staff, facilities, best place in Panama!"
United States
Ricardo E
The price is HK$3,742
HK$4,116 total
includes taxes & fees
29 Nov - 30 Nov
Sofitel Legend Casco Viejo, Panama City

3. Hotel La Compañía Casco Antiguo

Hotel La Compañía Casco Antiguo
5.0 star property
San Felipe, 0.5 km from El Machetazo Santa Ana
9.8 out of 10, Exceptional, (371 reviews)
"Execelente hotel."
United States
Carlos A
The price is HK$2,994
HK$3,293 total
includes taxes & fees
5 Nov - 6 Nov
Hotel La Compañía Casco Antiguo

4. Hotel Plaza Herrera

Hotel Plaza Herrera
4.0 star property
San Felipe, 0.4 km from El Machetazo Santa Ana
9.8 out of 10, Exceptional, (52 reviews)
"Everyone was so nice!"
United States
Christina
The price is HK$2,012
HK$2,213 total
includes taxes & fees
10 Nov - 11 Nov
Hotel Plaza Herrera

5. Casa Bianca

Casa Bianca
2.0 star property
Bella Vista, 2.6 km from El Machetazo Santa Ana
9.8 out of 10, Exceptional, (8 reviews)
"Good place , nice, clean, "
United States
Jose A
The price is HK$1,306
HK$1,437 total
includes taxes & fees
4 Dec - 5 Dec
Casa Bianca

6. La Concordia Boutique Hotel

La Concordia Boutique Hotel
4.0 star property
San Felipe, 0.2 km from El Machetazo Santa Ana
9.6 out of 10, Exceptional, (244 reviews)
"Such a beautiful and highly curated and very helpful staff."
United States
Jadah
The price is HK$1,765
HK$1,941 total
includes taxes & fees
6 Nov - 7 Nov
La Concordia Boutique Hotel

7. Hotel San Felipe

Hotel San Felipe
4.0 star property
San Felipe, 0.4 km from El Machetazo Santa Ana
9.4 out of 10, Exceptional, (472 reviews)
"Loved our stay! Central, clean, wonderful staff"
United States
RoseMarie
The price is HK$1,145
HK$1,260 total
includes taxes & fees
9 Nov - 10 Nov
Hotel San Felipe

8. American Trade Hotel

American Trade Hotel
4.5 star property
San Felipe, 0.4 km from El Machetazo Santa Ana
9.4 out of 10, Exceptional, (825 reviews)
"Very clean and nice staff"
United States
Conrad
The price is HK$1,814
HK$1,995 total
includes taxes & fees
10 Nov - 11 Nov
American Trade Hotel

9. Casa Lefevre By Wynwood House

Casa Lefevre By Wynwood House
3.0 star property
San Felipe, 0.5 km from El Machetazo Santa Ana
9.6 out of 10, Exceptional, (16 reviews)
"Staff was courteous, and the room was very beautiful. Would stay here again!"
United States
Selam
The price is HK$1,179
HK$1,513 total
includes taxes & fees
4 Nov - 5 Nov
Casa Lefevre By Wynwood House

10. Las Clementinas

Las Clementinas
3.5 star property
San Felipe, 0.2 km from El Machetazo Santa Ana
9.4 out of 10, Exceptional, (207 reviews)
"Great food and location"
United States
James
The price is HK$1,192
HK$1,468 total
includes taxes & fees
5 Nov - 6 Nov
Las Clementinas

11. Central Hotel Panama Casco Viejo

Central Hotel Panama Casco Viejo
4.0 star property
San Felipe, 0.5 km from El Machetazo Santa Ana
9.2 out of 10, Wonderful, (1,010 reviews)
"Property was clean and nice, breakfast was excellent."
United States
Moejha
The price is HK$1,594
HK$1,754 total
includes taxes & fees
3 Dec - 4 Dec
Central Hotel Panama Casco Viejo

12. Marriott Panama Hotel

Marriott Panama Hotel
4.0 star property
2.4 km from El Machetazo Santa Ana
9.2 out of 10, Wonderful, (1,003 reviews)
"Excellent location"
United States
Guadalupe
The price is HK$1,397
HK$1,536 total
includes taxes & fees
4 Dec - 5 Dec
Marriott Panama Hotel

13. Bristol Panama, a Registry Collection Hotel

Bristol Panama, a Registry Collection Hotel
5.0 star property
Bella Vista, 3.2 km from El Machetazo Santa Ana
9.2 out of 10, Wonderful, (1,000 reviews)
"was good"
United States
Juliet
The price is HK$1,660
HK$1,826 total
includes taxes & fees
15 Nov - 16 Nov
Bristol Panama, a Registry Collection Hotel

14. Hotel Bardot Boutique

Hotel Bardot Boutique
3.0 star property
San Felipe, 0.8 km from El Machetazo Santa Ana
9.0 out of 10, Wonderful, (66 reviews)
"Excellent location to walk around, visit local attractions and restaurants in the old city."
United States
Luz
The price is HK$713
HK$785 total
includes taxes & fees
9 Nov - 10 Nov
Hotel Bardot Boutique

15. Hilton Panama

Hilton Panama
5.0 star property
Bella Vista, 3 km from El Machetazo Santa Ana
9.0 out of 10, Wonderful, (1,002 reviews)
"Perfect location close to the financial district, local markets, and great restaurants."
United States
Simon
The price is HK$1,961
HK$2,157 total
includes taxes & fees
4 Dec - 5 Dec
Hilton Panama

16. W Panama

W Panama
5.0 star property
Campo Alegre, 3.2 km from El Machetazo Santa Ana
9.0 out of 10, Wonderful, (1,005 reviews)
"Our entire stay was amazing. Thank you to the staff to the front desk, wet bar, indoor bars & room service were outstanding. Thank you for an outstanding birthday!!"
United States
Mervyn
The price is HK$2,026
HK$2,229 total
includes taxes & fees
4 Dec - 5 Dec
W Panama

17. Hotel Magnolia Boutique

Hotel Magnolia Boutique
2.0 star property
San Felipe, 0.4 km from El Machetazo Santa Ana
8.8 out of 10, Excellent, (539 reviews)
"Fantastic location and very friendly, helpful staff. Highly recommended!"
Canada
Cathy
The price is HK$623
HK$686 total
includes taxes & fees
5 Nov - 6 Nov
Hotel Magnolia Boutique

18. Casco View Life Residences

Casco View Life Residences
4.0 star property
Santa Ana, 0.2 km from El Machetazo Santa Ana
9.0 out of 10, Wonderful, (114 reviews)
"Amazing location and comfort"
United States
Ruben
The price is HK$657
HK$958 total
includes taxes & fees
29 Nov - 30 Nov
Casco View Life Residences

19. Waldorf Astoria Panama

Waldorf Astoria Panama
5.0 star property
Bella Vista, 2.9 km from El Machetazo Santa Ana
9.0 out of 10, Wonderful, (1,001 reviews)
"The room was very nice, the bar staff and front desk staff were very helpful."
United States
Oscar
The price is HK$2,173
HK$2,390 total
includes taxes & fees
7 Nov - 8 Nov
Waldorf Astoria Panama

20. Tantalo Hotel

Tantalo Hotel
3.5 star property
San Felipe, 0.4 km from El Machetazo Santa Ana
8.8 out of 10, Excellent, (342 reviews)
"Excellent experience and def would return!"
United States
Andrew
The price is HK$780
HK$858 total
includes taxes & fees
23 Nov - 24 Nov
Tantalo Hotel
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Compare popular hotels close to El Machetazo Santa Ana

Property
Property class
Guest rating
Breakfast included
Pool
Spa
Pet-friendly
WiFi included
A spacious indoor courtyard with tiled flooring, multiple seating areas, and hanging plants.
La Isabela Suites
3.5 star property
10.0
Exceptional
213 reviews
View
A balcony with a table, chairs, and a view of a city skyline across a body of water.
Sofitel Legend Casco Viejo, Panama City
5.0 star property
9.8
Exceptional
771 reviews
View
A restaurant with multiple dining tables, chairs, and a central water feature.
Hotel La Compañía Casco Antiguo
5.0 star property
9.8
Exceptional
371 reviews
View
A multi-story building with ornate balconies, large windows, and decorative moldings.
Hotel Plaza Herrera
4.0 star property
9.8
Exceptional
52 reviews
View
A modern living room with a sectional sofa, a small ottoman, a flat-screen TV, and abstract art on the walls.
Casa Bianca
2.0 star property
9.8
Exceptional
8 reviews
View

Top El Machetazo Santa Ana Hotel Reviews

Other attractions near El Machetazo Santa Ana

Frequently asked questions

What's the area like around El Machetazo Santa Ana?
El Machetazo Santa Ana is located in Panama City. If you're looking for a convenient place to stay, take a look at the 518 hotels and other accommodation options you'll find within a mile.
Where is the best place to stay close to El Machetazo Santa Ana?
Adjacent to El Machetazo Santa Ana, Hotel Casa Panamá is one of the top choices for your stay based on our traveller data, and this hotel offers 2 restaurants and a nightclub. Other good choices close by include Central Hotel Panama Casco Viejo and Hotel Faranda Express Soloy and Casino, a member of Radisson Individuals.
How many hotels will I find close to El Machetazo Santa Ana?
Expedia has 518 hotels and other accommodation options within a mile from El Machetazo Santa Ana.
If I need to cancel the hotel reservation for my stay near El Machetazo Santa Ana, will I receive a refund?
Yes! Most hotel bookings are fully refundable as long as you cancel before the hotel's cancellation deadline, which often is within 24-48 hours of your scheduled arrival. If your reservation is non-refundable, you might be able to cancel it and get a refund within a 24-hour period of your booking. Add dates, click "Search", then filter by "fully refundable" to review the top deals on offer near El Machetazo Santa Ana.
What can I see and do near El Machetazo Santa Ana?
You'll want to browse the collections at Interoceanic Canal Museum, Biomuseo and Mola Museum. Explore landmarks like Iglesia del Carmen, Panama Canal Railway and Iglesia de la Merced. You can check out the local talent at National Theater, Amador Theater and Anita Villalaz Theater.