Key West Florida Keys Eco - Discovery Center Hotels

Start date: Check-in selected.
To Date
End date: Check-out

  • Change your mind

    Book hotels with free cancellation

  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in

  • Be picky

    Search almost a million properties worldwide

Check prices for these dates

Tonight
29 Dec - 30 Dec
Tomorrow
30 Dec - 31 Dec
This weekend
2 Jan - 4 Jan
Next weekend
9 Jan - 11 Jan

Filter by

Guest rating
Guest rating
Star rating

Our top choices for Florida Keys Eco - Discovery Center hotels

Egyptian cotton sheets, premium bedding, down duvets, pillow-top beds
Almond Tree Inn Hotel - Adults Only

Almond Tree Inn Hotel - Adults Only

Almond Tree Inn Hotel - Adults Only
3.5 star property
Downtown Key West, 0.8 km from Florida Keys Eco - Discovery Center
10.0 out of 10, Exceptional, (1000)
"Great location, spotless rooms, attentive and friendly staff, great value."
United States
David
The price is HK$3,144
HK$3,537 total
includes taxes & fees
4 Jan - 5 Jan 2026
Almond Tree Inn Hotel - Adults Only
Exterior
Orchid Key Inn - Adults Only

Orchid Key Inn - Adults Only

Orchid Key Inn - Adults Only
3.5 star property
Uptown - Upper Duval, 0.7 km from Florida Keys Eco - Discovery Center
9.8 out of 10, Exceptional, (1001)
"Staff awesome, good breakfast great location"
United States
Carin helen
The price is HK$3,117
HK$3,507 total
includes taxes & fees
4 Jan - 5 Jan 2026
Orchid Key Inn - Adults Only
Terrace/patio
The Gardens Hotel

The Gardens Hotel

The Gardens Hotel
4.0 star property
Downtown Key West, 0.7 km from Florida Keys Eco - Discovery Center
9.8 out of 10, Exceptional, (1002)
"Loved it. The staff were very friendly and the place was classic Key West."
United States
Ben
The price is HK$3,139
HK$3,531 total
includes taxes & fees
5 Jan - 6 Jan 2026
The Gardens Hotel
Front of property
Key West Villas

Key West Villas

Key West Villas
3.5 star property
Downtown Key West, 0.7 km from Florida Keys Eco - Discovery Center
9.8 out of 10, Exceptional, (247)
"Awsome staff great location "
United States
Jeffrey
Key West Villas
Balcony
Simonton Court Historic Inn & Cottages

Simonton Court Historic Inn & Cottages

Simonton Court Historic Inn & Cottages
2.5 star property
Historic Seaport, 0.9 km from Florida Keys Eco - Discovery Center
9.8 out of 10, Exceptional, (886)
"I loved staying here! The room was great and the staff was awesome! "
United States
Tiffany
The price is HK$2,115
HK$2,380 total
includes taxes & fees
8 Jan - 9 Jan 2026
Simonton Court Historic Inn & Cottages
Restaurant
Artist House Key West

Artist House Key West

Artist House Key West
3.5 star property
Historic Seaport, 0.9 km from Florida Keys Eco - Discovery Center
9.8 out of 10, Exceptional, (422)
"Really great place to stay. Nice rooms and staff. Great location for Devaul street. "
United States
Beth
The price is HK$2,440
HK$2,745 total
includes taxes & fees
12 Jan - 13 Jan 2026
Artist House Key West
Exterior
Coco Plum Inn

Coco Plum Inn

Coco Plum Inn
3.0 star property
Downtown Key West, 0.5 km from Florida Keys Eco - Discovery Center
9.6 out of 10, Exceptional, (470)
"The Coco Plum Inn is a wonderful place to stay. Staff is fantastic and the location is perfect. We will definitely come back and stay at the Coco Plum Inn."
United States
Brent
The price is HK$2,441
HK$2,746 total
includes taxes & fees
4 Jan - 5 Jan 2026
Coco Plum Inn
Exterior
The Marquesa Hotel

The Marquesa Hotel

The Marquesa Hotel
3.5 star property
Historic Seaport, 0.8 km from Florida Keys Eco - Discovery Center
9.8 out of 10, Exceptional, (1000)
"Perfect place to stay. "
United States
Paulette
The price is HK$3,101
HK$3,926 total
includes taxes & fees
4 Jan - 5 Jan 2026
The Marquesa Hotel
Garden
Douglas House

Douglas House

Douglas House
3.0 star property
Uptown - Upper Duval, 0.8 km from Florida Keys Eco - Discovery Center
9.6 out of 10, Exceptional, (238)
"Excellent spot, I definitely recommended"
United States
Paul
The price is HK$1,899
HK$2,350 total
includes taxes & fees
13 Jan - 14 Jan 2026
Douglas House
Outdoor pool, pool loungers
The Conch House Heritage Inn

The Conch House Heritage Inn

The Conch House Heritage Inn
3.5 star property
Old Town Key West, 1 km from Florida Keys Eco - Discovery Center
9.8 out of 10, Exceptional, (146)
"Check in was quick, easy. "
United States
kristen
The price is HK$2,966
HK$3,336 total
includes taxes & fees
4 Jan - 5 Jan 2026
The Conch House Heritage Inn
View from room
H2O Suites - Adults Only

H2O Suites - Adults Only

H2O Suites - Adults Only
3.5 star property
Uptown - Upper Duval, 1 km from Florida Keys Eco - Discovery Center
9.8 out of 10, Exceptional, (582)
"Great place!!"
United States
Joel
The price is HK$3,878
HK$4,887 total
includes taxes & fees
4 Jan - 5 Jan 2026
H2O Suites - Adults Only
Outdoor pool, pool loungers
The Mermaid & Alligator

The Mermaid & Alligator

The Mermaid & Alligator
3.5 star property
Old Town Key West, 1.1 km from Florida Keys Eco - Discovery Center
9.8 out of 10, Exceptional, (276)
"Great place"
United States
Carol A
The Mermaid & Alligator
Premium bedding, pillow-top beds, individually decorated
Tropical Inn

Tropical Inn

Tropical Inn
3.5 star property
Downtown Key West, 0.7 km from Florida Keys Eco - Discovery Center
9.6 out of 10, Exceptional, (364)
"Nice place to stay "
United States
yulio
The price is HK$2,146
HK$2,608 total
includes taxes & fees
4 Jan - 5 Jan 2026
Tropical Inn
Premium bedding, iron/ironing board, free WiFi, bed sheets
Weatherstation Inn

Weatherstation Inn

Weatherstation Inn
2.5 star property
Truman Annex, 0.5 km from Florida Keys Eco - Discovery Center
9.4 out of 10, Exceptional, (997)
"Wonderful property safe neighborhood convenient to all activities would stay here again."
United States
William
The price is HK$2,735
HK$3,077 total
includes taxes & fees
5 Jan - 6 Jan 2026
Weatherstation Inn
Front of property
L'Habitation Guest House

L'Habitation Guest House

L'Habitation Guest House
2.5 star property
Historic Seaport, 0.7 km from Florida Keys Eco - Discovery Center
9.4 out of 10, Exceptional, (925)
"A great no hassle stay."
United States
Gary
The price is HK$1,896
HK$2,133 total
includes taxes & fees
8 Jan - 9 Jan 2026
L'Habitation Guest House
View from property
Duval House

Duval House

Duval House
3.0 star property
Downtown Key West, 0.7 km from Florida Keys Eco - Discovery Center
9.4 out of 10, Exceptional, (1003)
"Great place! "
United States
David
The price is HK$1,935
HK$2,344 total
includes taxes & fees
6 Jan - 7 Jan 2026
Duval House
Fountain
Island City House Hotel

Island City House Hotel

Island City House Hotel
3.0 star property
Historic Seaport, 1.1 km from Florida Keys Eco - Discovery Center
9.6 out of 10, Exceptional, (1001)
"Excellent stay"
United States
Emily Barbara
The price is HK$3,112
HK$3,501 total
includes taxes & fees
11 Jan - 12 Jan 2026
Island City House Hotel
Outdoor pool, pool umbrellas, pool loungers
Marrero's Guest Mansion

Marrero's Guest Mansion

Marrero's Guest Mansion
3.5 star property
Downtown Key West, 0.6 km from Florida Keys Eco - Discovery Center
9.4 out of 10, Exceptional, (335)
"Location very good Staff friendly Pool not well maintained Breakfast and happy hour lacking compared to others"
United States
Scott
The price is HK$2,914
HK$3,279 total
includes taxes & fees
5 Jan - 6 Jan 2026
Marrero's Guest Mansion
Terrace/patio
Alexanders Guesthouse - Adult Exclusive, LGBTQ Friendly

Alexanders Guesthouse - Adult Exclusive, LGBTQ Friendly

Alexanders Guesthouse - Adult Exclusive, LGBTQ Friendly
3.5 star property
Old Town Key West, 1.6 km from Florida Keys Eco - Discovery Center
9.8 out of 10, Exceptional, (136)
"We absolutely loved finding this gem to stay on our first visit to Key West. Great location, wonderful staff, and excellent room. "
United States
Sammy
Alexanders Guesthouse - Adult Exclusive, LGBTQ Friendly
Terrace/patio
Caribbean House

Caribbean House

Caribbean House
3.0 star property
Bahama Village, 0.4 km from Florida Keys Eco - Discovery Center
9.2 out of 10, Wonderful, (290)
"Very nice and would stay again. It was close to a few of our favorite restaurants "
United States
Leonard Frisch
The price is HK$2,537
HK$3,048 total
includes taxes & fees
1 Jan - 2 Jan 2026
Caribbean House
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

Top Florida Keys Eco - Discovery Center Hotel Reviews

Opal Key Resort & Marina, Key West

Opal Key Resort & Marina, Key West

10/10 Excellent
"Room was beautiful. Friendly staff with great amenities. Very busy area with cruise ships docking everyday. "
Emily 6-night trip
Posted 22 hours ago
Opal Key Resort & Marina, Key West

Hotels near other Florida Keys Eco - Discovery Center attractions

Fort Zachary Taylor Park, Key West. State Park in Florida, USA., Shutterstock ID 761867707, Purchase Order: SP-1891 Wave 0, Client/Licensee: Hotels.com

Fort Zachary Taylor Historic State Park

4.4/5 (1,160 reviews)
The displays of old weapons and interpretive panels in a fort at the heart of the southernmost state park in the continental U.S. provide information about the Civil War.
See properties
Jackson Square showing a garden

Jackson Square

You can learn about the history of Key West with a trip to Jackson Square. Stroll along the seaside or discover the area's beautiful sunsets.
See properties

Frequently asked questions

What's the area like around Florida Keys Eco - Discovery Center?
Florida Keys Eco - Discovery Center is located in an area of Key West known for its beautiful ocean views, bar scene and lively festivals. If you're looking for a convenient place to stay, take a look at the 1675 hotels and other accommodation options you'll find within a mile.
Where is the best place to stay near Florida Keys Eco - Discovery Center?
Adjacent to Florida Keys Eco - Discovery Center, Caribbean House is one of the top choices for your stay based on our traveller data, and this B&B offers free breakfast and private balconies. Other good choices within a short distance include Southernmost Beach Resort and Guesthouses and La Concha Key West, Autograph Collection.
How many hotels will I find close to Florida Keys Eco - Discovery Center?
Expedia has 1675 hotels and other accommodation options within a mile from Florida Keys Eco - Discovery Center.
If I need to cancel the hotel reservation for my stay near Florida Keys Eco - Discovery Center, will I receive a refund?
Yes! You'll find that most room reservations are refundable if you cancel before the accommodation's cancellation deadline, which often is within 24-48 hours of your scheduled arrival. If you have a reservation that's non-refundable, it might still be possible to cancel it and receive a refund within 24 hours of your booking. Enter your dates, click on "Search", then filter by "fully refundable" to get the top deals on offer near Florida Keys Eco - Discovery Center.
What can I see and do near Florida Keys Eco - Discovery Center?
Study the collections at Key West Lighthouse and Keeper's Quarters Museum, Ernest Hemingway Home and Museum or Harry S. Truman Little White House. While you're exploring, swing by Fort Zachary Taylor Historic State Park, Audubon House and Tropical Gardens and Key West Historic Seaport to learn a bit about the area. You can catch a show at Red Barn Theater, Key West Film Society and Waterfront Playhouse.