
Hyannis Main Street Hyannis Hotels
- Change your mindBook hotels with free cancellation
- Be pickySearch almost a million properties worldwide
Check prices for these dates
Our top choices for Main Street Hyannis hotels

Sea Street Inn
Sea Street Inn1.5 km from Main Street Hyannis
9.8 out of 10, Exceptional, (45 reviews)
The price is HK$1,797
HK$2,057 total
includes taxes & fees
22 Feb - 23 Feb

Anchor In Distinctive Waterfront Lodging
Anchor In Distinctive Waterfront Lodging0.6 km from Main Street Hyannis
9.4 out of 10, Exceptional, (1,002 reviews)
The price is HK$923
HK$1,280 total
includes taxes & fees
22 Feb - 23 Feb

Uncommoner Hotel by Reverie Boutique Collection
Uncommoner Hotel by Reverie Boutique Collection1.9 km from Main Street Hyannis
9.4 out of 10, Exceptional, (112 reviews)
The price is HK$920
HK$1,089 total
includes taxes & fees
27 Feb - 28 Feb

Hampton Inn & Suites Cape Cod-West Yarmouth
Hampton Inn & Suites Cape Cod-West Yarmouth1.7 km from Main Street Hyannis
8.8 out of 10, Excellent, (1,000 reviews)
The price is HK$827
HK$946 total
includes taxes & fees
15 Mar - 16 Mar

Bayside Resort Hotel
Bayside Resort Hotel2.3 km from Main Street Hyannis
8.8 out of 10, Excellent, (1,549 reviews)
The price is HK$731
HK$926 total
includes taxes & fees
1 Mar - 2 Mar

Fairfield Inn & Suites by Marriott Cape Cod Hyannis
Fairfield Inn & Suites by Marriott Cape Cod Hyannis2.3 km from Main Street Hyannis
8.8 out of 10, Excellent, (679 reviews)
The price is HK$961
HK$1,100 total
includes taxes & fees
24 Feb - 25 Feb

Courtyard Resort
Courtyard Resort0.3 km from Main Street Hyannis
8.4 out of 10, Very good, (59 reviews)
The price is HK$852
HK$975 total
includes taxes & fees
22 Feb - 23 Feb

Courtyard By Marriott Cape Cod Hyannis
Courtyard By Marriott Cape Cod Hyannis1.7 km from Main Street Hyannis
8.8 out of 10, Excellent, (493 reviews)
The price is HK$1,064
HK$1,218 total
includes taxes & fees
1 Mar - 2 Mar

Heritage House Inn on Cape Cod, an Ascend Collection Hotel
Heritage House Inn on Cape Cod, an Ascend Collection Hotel0.3 km from Main Street Hyannis
8.4 out of 10, Very good, (20 reviews)
The price is HK$790
HK$905 total
includes taxes & fees
1 Mar - 2 Mar

Doubletree by Hilton Cape Cod - Hyannis
Doubletree by Hilton Cape Cod - Hyannis0.9 km from Main Street Hyannis
8.4 out of 10, Very good, (891 reviews)
The price is HK$997
HK$1,142 total
includes taxes & fees
21 Mar - 22 Mar

Comfort Inn Hyannis - Cape Cod
Comfort Inn Hyannis - Cape Cod0.3 km from Main Street Hyannis
8.0 out of 10, Very good, (1,001 reviews)
The price is HK$714
HK$817 total
includes taxes & fees
26 Feb - 27 Feb

Cape Sands Inn
Cape Sands Inn1.9 km from Main Street Hyannis
8.2 out of 10, Very good, (1,023 reviews)
The price is HK$583
HK$667 total
includes taxes & fees
22 Feb - 23 Feb

Hyannis Harbor Hotel
Hyannis Harbor Hotel0.6 km from Main Street Hyannis
8.0 out of 10, Very good, (1,003 reviews)
The price is HK$869
HK$1,311 total
includes taxes & fees
22 Feb - 23 Feb

Holiday Inn Hyannis by IHG
Holiday Inn Hyannis by IHG2.9 km from Main Street Hyannis
8.2 out of 10, Very good, (989 reviews)
The price is HK$891
HK$1,020 total
includes taxes & fees
24 Feb - 25 Feb

Sea Breeze Inn
Sea Breeze Inn1.8 km from Main Street Hyannis
7.8 out of 10, Good, (193 reviews)
The price is HK$695
HK$796 total
includes taxes & fees
21 Feb - 22 Feb

Hyannis Plaza Hotel
Hyannis Plaza Hotel0.9 km from Main Street Hyannis
7.0 out of 10, Good, (1,000 reviews)
The price is HK$643
HK$815 total
includes taxes & fees
22 Feb - 23 Feb

Sal's Place
Sal's Place2.5 km from Main Street Hyannis
The price is HK$3,126
HK$4,515 total
includes taxes & fees
22 Feb - 23 Feb

The Village Inn Cape Cod
The Village Inn Cape Cod6.1 km from Main Street Hyannis
10.0 out of 10, Exceptional, (224 reviews)
The price is HK$1,602
HK$1,833 total
includes taxes & fees
21 Feb - 22 Feb

Inn on Main
Inn on Main6.4 km from Main Street Hyannis
10.0 out of 10, Exceptional, (74 reviews)
The price is HK$1,927
HK$2,206 total
includes taxes & fees
21 Feb - 22 Feb

Margaritaville Resort Cape Cod
Margaritaville Resort Cape Cod3.3 km from Main Street Hyannis
8.8 out of 10, Excellent, (457 reviews)
The price is HK$979
HK$1,568 total
includes taxes & fees
22 Feb - 23 Feb
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Compare popular hotels close to Main Street Hyannis
Property | Property class | Guest rating | Breakfast included | Pool | Spa | Pet-friendly | WiFi included | |
|---|---|---|---|---|---|---|---|---|
![]() Sea Street Inn | 9.8 Exceptional 45 reviews | View | ||||||
![]() Anchor In Distinctive Waterfront Lodging | 9.4 Exceptional 1,002 reviews | View | ||||||
![]() Uncommoner Hotel by Reverie Boutique Collection | 9.4 Exceptional 112 reviews | View | ||||||
![]() Hampton Inn & Suites Cape Cod-West Yarmouth | 8.8 Excellent 1,000 reviews | View | ||||||
![]() Bayside Resort Hotel | 8.8 Excellent 1,549 reviews | View |
Top Main Street Hyannis Hotel Reviews

Anchor In Distinctive Waterfront Lodging
10/10 Excellent












































































