A storefront with a sign reading "The Beach Club" and various clothing items displayed in the window.

Hyannis Main Street Hyannis Hotels

  • Change your mind

    Book hotels with free cancellation

  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in

  • Be picky

    Search almost a million properties worldwide

Check prices for these dates

This weekend
17 Jul - 19 Jul
Next weekend
24 Jul - 26 Jul

Filter by

Guest rating
Guest rating
Star rating

Our top choices for Main Street Hyannis hotels

Exterior

Hyannis Travel Inn

Hyannis Travel Inn
2.5 star property
0.2 km from Main Street Hyannis
9.6 out of 10, Exceptional, (1,029 reviews)
"Great stay - friendly and helpful reception"
United States
Arminda
The price is HK$1,474
HK$1,687 total
includes taxes & fees
14 Jul - 15 Jul
Hyannis Travel Inn
Terrace/patio

Anchor In Distinctive Waterfront Lodging

Anchor In Distinctive Waterfront Lodging
3.0 star property
0.6 km from Main Street Hyannis
9.4 out of 10, Exceptional, (1,007 reviews)
"Great location and very accommodating staff."
United States
Jovian
The price is HK$2,314
HK$2,873 total
includes taxes & fees
27 Jul - 28 Jul
Anchor In Distinctive Waterfront Lodging
Exterior

Cape Cod Harbor House Inn

Cape Cod Harbor House Inn
2.5 star property
0.4 km from Main Street Hyannis
9.2 out of 10, Wonderful, (317 reviews)
"The room was super clean and the facility was centrally located. "
United States
Vincent
The price is HK$1,403
HK$1,606 total
includes taxes & fees
14 Jul - 15 Jul
Cape Cod Harbor House Inn
Iron/ironing board, free WiFi, bed sheets

SeaCoast Inn

SeaCoast Inn
2.0 star property
0.1 km from Main Street Hyannis
9.0 out of 10, Wonderful, (803 reviews)
"Great spot to stay right off the bustling Main Street of Hyannis."
United States
Krystal
The price is HK$1,325
HK$1,516 total
includes taxes & fees
23 Jul - 24 Jul
SeaCoast Inn
Egyptian cotton sheets, premium bedding, individually decorated

Sea Street Inn

Sea Street Inn
4.0 star property
1.5 km from Main Street Hyannis
9.8 out of 10, Exceptional, (46 reviews)
"Very nicely renovated small property with a fantastic breakfast."
United States
Paul
The price is HK$3,200
HK$3,663 total
includes taxes & fees
15 Jul - 16 Jul
Sea Street Inn
Exterior

Heritage House Inn on Cape Cod, an Ascend Collection Hotel

Heritage House Inn on Cape Cod, an Ascend Collection Hotel
2.5 star property
0.3 km from Main Street Hyannis
9.0 out of 10, Wonderful, (60 reviews)
"Great location, clean …we love it!!!!!"
United States
Aloisio
The price is HK$1,482
HK$1,696 total
includes taxes & fees
2 Aug - 3 Aug
Heritage House Inn on Cape Cod, an Ascend Collection Hotel
Indoor pool, seasonal outdoor pool

Uncommoner Hotel by Reverie Boutique Collection

Uncommoner Hotel by Reverie Boutique Collection
4.0 star property
1.9 km from Main Street Hyannis
9.4 out of 10, Exceptional, (210 reviews)
"Great place to stay and the staff members are amazing."
United States
Joseph
The price is HK$2,173
HK$2,574 total
includes taxes & fees
19 Jul - 20 Jul
Uncommoner Hotel by Reverie Boutique Collection
Marina

Cape Cod Inn

Cape Cod Inn
2.0 star property
0.2 km from Main Street Hyannis
8.6 out of 10, Excellent, (524 reviews)
"Great stay in a nice location. We just stayed a night on the way up the Cape. It was just what we needed. Simple, clean, and good location."
United States
Jamie
The price is HK$1,035
HK$1,184 total
includes taxes & fees
27 Jul - 28 Jul
Cape Cod Inn
View from property

Green Harbor Resort

Green Harbor Resort
3.0 star property
2.1 km from Main Street Hyannis
9.6 out of 10, Exceptional, (363 reviews)
"Wonderful resort, everything - amenities, grounds and rooms - so well taken care of."
United States
Douglas
The price is HK$3,598
HK$4,571 total
includes taxes & fees
29 Jul - 30 Jul
Green Harbor Resort
Indoor pool, outdoor pool

Freebird Motor Lodge by Reverie Boutique Collection

Freebird Motor Lodge by Reverie Boutique Collection
3.5 star property
4.2 km from Main Street Hyannis
9.6 out of 10, Exceptional, (309 reviews)
"Freebird was a great experience. We can’t wait to get back. Management and ownership should be proud of the staff."
United States
Jonathan
The price is HK$1,893
HK$2,242 total
includes taxes & fees
26 Jul - 27 Jul
Freebird Motor Lodge by Reverie Boutique Collection
Indoor pool

Courtyard By Marriott Cape Cod Hyannis

Courtyard By Marriott Cape Cod Hyannis
3.0 star property
1.7 km from Main Street Hyannis
8.8 out of 10, Excellent, (505 reviews)
"The parking and location were the only good things about this place. The room was filthy and bathroom was unsanitary."
United States
Emily
The price is HK$2,149
HK$2,460 total
includes taxes & fees
19 Jul - 20 Jul
Courtyard By Marriott Cape Cod Hyannis
Indoor pool, seasonal outdoor pool, pool umbrellas, pool loungers

Hampton Inn & Suites Cape Cod-West Yarmouth

Hampton Inn & Suites Cape Cod-West Yarmouth
2.5 star property
1.7 km from Main Street Hyannis
8.8 out of 10, Excellent, (1,007 reviews)
"Staff was very helpful and everything was great. Will definitely stay there again."
United States
Cynthia
The price is HK$2,243
HK$2,567 total
includes taxes & fees
20 Jul - 21 Jul
Hampton Inn & Suites Cape Cod-West Yarmouth
Indoor pool, seasonal outdoor pool, pool umbrellas, pool loungers

Bayside Resort Hotel

Bayside Resort Hotel
3.0 star property
2.3 km from Main Street Hyannis
8.8 out of 10, Excellent, (1,548 reviews)
"We enjoyed our time here"
United States
Lixuan
The price is HK$1,856
HK$2,214 total
includes taxes & fees
11 Aug - 12 Aug
Bayside Resort Hotel
Free daily continental breakfast

Comfort Inn Hyannis - Cape Cod

Comfort Inn Hyannis - Cape Cod
2.5 star property
0.3 km from Main Street Hyannis
8.2 out of 10, Very good, (1,009 reviews)
"Everything was on point. Breakfast in morning and everything is close by. Plus, its affordable as well."
United States
Vincent
The price is HK$1,333
HK$1,526 total
includes taxes & fees
16 Jul - 17 Jul
Comfort Inn Hyannis - Cape Cod
Exterior

Cape Cod Motor Inn

Cape Cod Motor Inn
2.5 star property
6 km from Main Street Hyannis
9.8 out of 10, Exceptional, (70 reviews)
"Everything about our stay was wonderful!"
United States
Jennifer
The price is HK$1,011
HK$1,157 total
includes taxes & fees
14 Jul - 15 Jul
Cape Cod Motor Inn
Individually furnished, iron/ironing board, free WiFi, bed sheets

Liberty Hill Inn

Liberty Hill Inn
3.5 star property
6 km from Main Street Hyannis
10.0 out of 10, Exceptional, (128 reviews)
"5* beautiful inn with fabulous hosts! Breakfast beyond what you’d expect, hot cookies in the afternoon, spotless inside, great attention to every detail!"
United States
Linda
The price is HK$2,508
HK$2,871 total
includes taxes & fees
15 Jul - 16 Jul
Liberty Hill Inn
Exterior

Doubletree by Hilton Cape Cod - Hyannis

Doubletree by Hilton Cape Cod - Hyannis
4.0 star property
0.9 km from Main Street Hyannis
8.4 out of 10, Very good, (923 reviews)
"Clean rooms. Comfy bed!"
United States
Rick
The price is HK$2,261
HK$2,588 total
includes taxes & fees
26 Jul - 27 Jul
Doubletree by Hilton Cape Cod - Hyannis
Front of property

Hyannis Harbor Hotel

Hyannis Harbor Hotel
3.5 star property
0.6 km from Main Street Hyannis
8.2 out of 10, Very good, (1,020 reviews)
"great location and great place"
United States
Rachel
The price is HK$2,109
HK$2,655 total
includes taxes & fees
16 Jul - 17 Jul
Hyannis Harbor Hotel
Exterior

Cape Sands Inn

Cape Sands Inn
2.5 star property
1.9 km from Main Street Hyannis
8.2 out of 10, Very good, (1,111 reviews)
"Great location, clean room, pool. Quiet."
United States
Laura
The price is HK$1,008
HK$1,154 total
includes taxes & fees
29 Jul - 30 Jul
Cape Sands Inn
Indoor pool, seasonal outdoor pool, pool loungers

Americas Best Value Inn & Suites Hyannis Cape Cod

Americas Best Value Inn & Suites Hyannis Cape Cod
2.0 star property
0.5 km from Main Street Hyannis
7.8 out of 10, Good, (1,007 reviews)
"It was nice place to stay"
United States
Celvin
The price is HK$1,011
HK$1,157 total
includes taxes & fees
14 Jul - 15 Jul
Americas Best Value Inn & Suites Hyannis Cape Cod
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

Compare popular hotels close to Main Street Hyannis

Property
Property class
Guest rating
Breakfast included
Pool
Spa
Pet-friendly
WiFi included
Exterior
Hyannis Travel Inn
2.5 star property
9.6
Exceptional
1,029 reviews
View
Terrace/patio
Anchor In Distinctive Waterfront Lodging
3.0 star property
9.4
Exceptional
1,007 reviews
View
Exterior
Cape Cod Harbor House Inn
2.5 star property
9.2
Wonderful
317 reviews
View
Iron/ironing board, free WiFi, bed sheets
SeaCoast Inn
2.0 star property
9.0
Wonderful
803 reviews
View
Egyptian cotton sheets, premium bedding, individually decorated
Sea Street Inn
4.0 star property
9.8
Exceptional
46 reviews
View

Top Main Street Hyannis Hotel Reviews

Bayside Resort Hotel

Bayside Resort Hotel

10/10 Excellent
"We stayed here for 4th of July weekend and it was wonderful!"
Ashley 3-night trip
Posted 5 hours ago
Bayside Resort Hotel

Hotels near other Main Street Hyannis attractions

A bronze statue of a man in a polo shirt standing in front of a building with a brick facade, white columns, and an American flag.

John F. Kennedy Hyannis Museum

8.8/10 (444 reviews)
Learn about the 35th president of the United States at this revealing museum, which is just a short distance from the Kennedy Compound.
See properties

Frequently asked questions

What's the area like around Main Street Hyannis?
Main Street Hyannis is located in a walkable area of Hyannis known for its top seafood restaurants and major shopping area. If you're looking for a convenient place to stay, take a look at the 199 hotels and other accommodation options you'll find within a mile.
Where is the best place to stay near Main Street Hyannis?
Adjacent to Main Street Hyannis, Hyannis Travel Inn is one of the top choices for your stay based on our traveller data, and this hotel offers free breakfast and an outdoor pool. Other good options within a short distance include Heritage House Inn on Cape Cod, an Ascend Collection Hotel and Hyannis Harbor Hotel.
How many hotels can I expect to find near Main Street Hyannis?
Expedia has 199 hotels and other accommodation options within a mile from Main Street Hyannis.
If I need to cancel the hotel reservation for my stay near Main Street Hyannis, will I receive a refund?
Yes! Most hotel reservations are fully refundable if cancelled prior to the accommodation's cancellation deadline, which is often 24 or 48 hours before your scheduled arrival. If your reservation is non-refundable, you might be able to still cancel and get a refund within 24 hours of your booking. Add dates, click "Search", then filter by "fully refundable" to review the top deals on offer near Main Street Hyannis.
What can I see and do near Main Street Hyannis?
John F. Kennedy Hyannis Museum, Cape Cod Maritime Museum and Whydah Pirate Museum feature captivating exhibits. Hyannis Harbor, Edward Gorey House and Sandy Neck Lighthouse are landmarks that you won't want to miss. Local parks like Lewis Bay, Veterans Memorial Park and Dennis Pond Conservation Area are peaceful spots to stop and take in some fresh air.