San Diego Medi Center Hotels

  • Change your mind

    Book hotels with free cancellation
  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
  • Be picky

    Search almost a million properties worldwide

Check prices for these dates

Filter by

Guest rating
Guest rating
Star rating

Our top choices for Medi Center hotels

Quality Inn San Diego I-5 Naval Base

Quality Inn San Diego I-5 Naval Base
2.5 star property
3.2 km from Medi Center
7.8 out of 10, Good, (889 reviews)
"Great place to stay"
United States
Jean Pierre
The price is HK$765
HK$864 total
includes taxes & fees
24 Jan - 25 Jan
Quality Inn San Diego I-5 Naval Base

Lodge at 32nd

Lodge at 32nd
2.5 star property
1.8 km from Medi Center
7.6 out of 10, Good, (804 reviews)
"Great price and location"
United States
Courtney
The price is HK$464
HK$611 total
includes taxes & fees
25 Jan - 26 Jan
Lodge at 32nd

Hard Rock Hotel San Diego

Hard Rock Hotel San Diego
4.0 star property
Gaslamp Quarter, 5 km from Medi Center
9.0 out of 10, Wonderful, (3,258 reviews)
"Great place to stay!"
United States
CINDY
The price is HK$3,565
HK$4,505 total
includes taxes & fees
3 Feb - 4 Feb
Hard Rock Hotel San Diego

Stay Classy Hostel

Stay Classy Hostel
2.0 star property
East Village, 4.2 km from Medi Center
9.4 out of 10, Exceptional, (800 reviews)
"Good place to stay "
United States
sai
Stay Classy Hostel

Sentral Gaslamp Quarter

Sentral Gaslamp Quarter
4.0 star property
East Village, 4.6 km from Medi Center
9.4 out of 10, Exceptional, (643 reviews)
"Great place to stay "
United States
KELLY
The price is HK$921
HK$1,294 total
includes taxes & fees
25 Jan - 26 Jan
Sentral Gaslamp Quarter

Staypineapple, Hotel Z, Gaslamp San Diego

Staypineapple, Hotel Z, Gaslamp San Diego
3.0 star property
Gaslamp Quarter, 4.9 km from Medi Center
9.4 out of 10, Exceptional, (1,002 reviews)
"Great location and stay. "
United States
Simran
The price is HK$772
HK$1,120 total
includes taxes & fees
26 Jan - 27 Jan
Staypineapple, Hotel Z, Gaslamp San Diego

Palihotel San Diego Gaslamp Quarter

Palihotel San Diego Gaslamp Quarter
4.0 star property
Gaslamp Quarter, 5 km from Medi Center
8.6 out of 10, Excellent, (2,194 reviews)
"Excellent location, wonderful staff."
United States
phuc
The price is HK$975
HK$1,130 total
includes taxes & fees
25 Jan - 26 Jan
Palihotel San Diego Gaslamp Quarter

The DEXTRO Little Italy, BW Premier Collection

The DEXTRO Little Italy, BW Premier Collection
3.0 star property
5.5 km from Medi Center
9.0 out of 10, Wonderful, (949 reviews)
"Great stay. Would definitely stay again."
United States
Zoraima
The price is HK$912
HK$1,058 total
includes taxes & fees
22 Feb - 23 Feb
The DEXTRO Little Italy, BW Premier Collection

Holiday Inn Express San Diego South - National City by IHG

Holiday Inn Express San Diego South - National City by IHG
2.5 star property
4.2 km from Medi Center
8.4 out of 10, Very good, (1,001 reviews)
"Clean rooms, great breakfast!"
United States
Ramiro
The price is HK$928
HK$1,022 total
includes taxes & fees
25 Jan - 26 Jan
Holiday Inn Express San Diego South - National City by IHG

Marriott Vacation Club®, San Diego

Marriott Vacation Club®, San Diego
3.5 star property
4.9 km from Medi Center
9.4 out of 10, Exceptional, (1,003 reviews)
"Great place to stay!"
Canada
Rose Marie JOy
The price is HK$1,255
HK$1,455 total
includes taxes & fees
15 Feb - 16 Feb
Marriott Vacation Club®, San Diego

Residence Inn by Marriott San Diego Downtown/Gaslamp Quarter

Residence Inn by Marriott San Diego Downtown/Gaslamp Quarter
3.0 star property
Gaslamp Quarter, 5 km from Medi Center
9.0 out of 10, Wonderful, (1,257 reviews)
"Friendly staff, great location, excellent value overall "
United States
Maryann
The price is HK$1,241
HK$1,439 total
includes taxes & fees
25 Jan - 26 Jan
Residence Inn by Marriott San Diego Downtown/Gaslamp Quarter

Gaslamp Plaza Suites

Gaslamp Plaza Suites
3.5 star property
Gaslamp Quarter, 5 km from Medi Center
9.0 out of 10, Wonderful, (1,024 reviews)
"Loved the staff very welcoming. Room was good and comfortable. Perfect location. This is our 3rd time here and definitely will come back. "
United States
SONIA
The price is HK$928
HK$1,055 total
includes taxes & fees
25 Jan - 26 Jan
Gaslamp Plaza Suites

Moxy San Diego Downtown/Gaslamp Quarter

Moxy San Diego Downtown/Gaslamp Quarter
3.5 star property
Gaslamp Quarter, 4.9 km from Medi Center
9.0 out of 10, Wonderful, (1,002 reviews)
"Amazing stay over all! Everything was great. Staff was friendly. "
United States
Nancy
The price is HK$889
HK$1,101 total
includes taxes & fees
25 Jan - 26 Jan
Moxy San Diego Downtown/Gaslamp Quarter

Best Western Plus Marina Gateway Hotel

Best Western Plus Marina Gateway Hotel
3.5 star property
5.7 km from Medi Center
9.2 out of 10, Wonderful, (3,673 reviews)
"Great place"
United States
Gustavo
The price is HK$1,116
HK$1,230 total
includes taxes & fees
28 Jan - 29 Jan
Best Western Plus Marina Gateway Hotel

Howard Johnson by Wyndham National City/San Diego South

Howard Johnson by Wyndham National City/San Diego South
2.0 star property
3.7 km from Medi Center
7.4 out of 10, Good, (1,002 reviews)
"Decent place for Decent money. Only thing i will complain is the location breakfast but nothing else.. very friendly place ."
United States
Edgar m
The price is HK$477
HK$526 total
includes taxes & fees
2 Feb - 3 Feb
Howard Johnson by Wyndham National City/San Diego South

Gaslamp Hostel

Gaslamp Hostel
2.0 star property
Gaslamp Quarter, 5.1 km from Medi Center
9.2 out of 10, Wonderful, (550 reviews)
"The staff was always so nice and friendly, breakfast options were just cereals. The room and bathrooms were always clean so 10/10 "
United States
Adriana
Gaslamp Hostel

The Bristol Hotel San Diego

The Bristol Hotel San Diego
3.5 star property
5.4 km from Medi Center
8.6 out of 10, Excellent, (1,474 reviews)
"Newly remodeled rooms, clean and wonderful staff. "
United States
Zoe
The Bristol Hotel San Diego

Courtyard by Marriott San Diego Gaslamp/Convention Center

Courtyard by Marriott San Diego Gaslamp/Convention Center
3.0 star property
Gaslamp Quarter, 5 km from Medi Center
8.6 out of 10, Excellent, (1,001 reviews)
"Very nice place to stay"
United States
Mike
The price is HK$1,209
HK$1,471 total
includes taxes & fees
25 Jan - 26 Jan
Courtyard by Marriott San Diego Gaslamp/Convention Center

The Beau Downtown San Diego Gaslamp Quar

The Beau Downtown San Diego Gaslamp Quar
3.0 star property
Gaslamp Quarter, 5 km from Medi Center
8.8 out of 10, Excellent, (580 reviews)
"A very nice spot to stay in the gas lamp district. "
United States
Janet
The price is HK$971
HK$1,104 total
includes taxes & fees
25 Jan - 26 Jan
The Beau Downtown San Diego Gaslamp Quar

Omni San Diego Hotel at the Ballpark

Omni San Diego Hotel at the Ballpark
4.0 star property
Gaslamp Quarter, 4.9 km from Medi Center
9.2 out of 10, Wonderful, (2,056 reviews)
"Great location, clean and comfortable rooms, friendly staff."
United States
Maya
The price is HK$1,783
HK$2,420 total
includes taxes & fees
29 Jan - 30 Jan
Omni San Diego Hotel at the Ballpark
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Top Medi Center Hotel Reviews

Hotels near other Medi Center attractions

Frequently asked questions

What's the area like around Medi Center?
Medi Center is located in San Diego. If you're looking for a convenient place to stay, take a look at the 23 hotels and other accommodation options you'll find within a mile.
What's the best place to stay near Medi Center?
Hard Rock Hotel San Diego is one of the top choices for your stay based on our traveller data, and this hotel offers 2 restaurants and an outdoor pool. It's located 3.1 mi (5 km) from Medi Center. Other good choices within 5 miles include Pendry San Diego and The US Grant, a Luxury Collection Hotel, San Diego.
How many hotels should I expect to find near Medi Center?
Expedia has 23 hotels and other accommodation options within a mile from Medi Center.
If I need to cancel the hotel reservation for my stay near Medi Center, will I receive a refund?
Yes, most room reservations are refundable provided that you cancel prior to the accommodation's cancellation deadline, which is usually within 24-48 hours of your check-in date. If your reservation is non-refundable, you may still be able to cancel and be given a refund within a 24-hour period of your booking. Plug in your dates, click on "Search", then use the "fully refundable" filter to view top deals close to Medi Center.
What can I see and do near Medi Center?
San Diego Natural History Museum, San Diego Air and Space Museum and Maritime Museum of San Diego feature a variety of fascinating exhibits to see while you're in town. Hotel del Coronado, Star of India and Nu-Way Christian Ministries are some of the notable landmarks to see in the area. You can watch performances at San Diego Civic Theatre, The Rady Shell at Jacobs Park and Cal Coast Credit Union Open Air Theater if you're interested in local theatre.