Powell North Knoxville Medical Center Hotels

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23 Dec - 24 Dec
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24 Dec - 25 Dec
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26 Dec - 28 Dec
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2 Jan - 4 Jan

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Our top choices for North Knoxville Medical Center hotels

Premium bedding, down duvets, pillow-top beds, desk
Comfort Inn Powell - Knoxville North

Comfort Inn Powell - Knoxville North

Comfort Inn Powell - Knoxville North
2.5 star property
0.4 km from North Knoxville Medical Center
8.8 out of 10, Excellent, (1000)
"Friendly staff, quiet, good breakfast. Really enjoyed our stay"
United States
antonio
The price is HK$773
HK$883 total
includes taxes & fees
3 Jan - 4 Jan 2026
Comfort Inn Powell - Knoxville North
Free buffet breakfast on weekends
Holiday Inn Express & Suites Knoxville-North-I-75 Exit 112 by IHG

Holiday Inn Express & Suites Knoxville-North-I-75 Exit 112 by IHG

Holiday Inn Express & Suites Knoxville-North-I-75 Exit 112 by IHG
2.5 star property
0.3 km from North Knoxville Medical Center
8.4 out of 10, Very good, (906)
"Great customer service and rooms were good"
United States
Kristi
The price is HK$739
HK$844 total
includes taxes & fees
6 Jan - 7 Jan 2026
Holiday Inn Express & Suites Knoxville-North-I-75 Exit 112 by IHG
Exterior
La Quinta Inn & Suites by Wyndham Knoxville North I-75

La Quinta Inn & Suites by Wyndham Knoxville North I-75

La Quinta Inn & Suites by Wyndham Knoxville North I-75
3.0 star property
0.2 km from North Knoxville Medical Center
7.4 out of 10, Good, (1000)
"The price for my room was better than other places in the area, and I'd stayed at a La Quinta Inn before in Sierra Vista, AZ, so I was familiar with the level of quality, the cleanliness, and excellent service."
United States
Stephen
The price is HK$670
HK$765 total
includes taxes & fees
28 Dec - 29 Dec
La Quinta Inn & Suites by Wyndham Knoxville North I-75
Jetted bathtub
Baymont by Wyndham Knoxville I-75

Baymont by Wyndham Knoxville I-75

Baymont by Wyndham Knoxville I-75
2.5 star property
3.1 km from North Knoxville Medical Center
6.6 out of 10, (1004)
"Clean and quiet facilities."
United States
Rebecca
The price is HK$423
HK$501 total
includes taxes & fees
28 Dec - 29 Dec
Baymont by Wyndham Knoxville I-75
Lobby
Days Inn by Wyndham Knoxville North

Days Inn by Wyndham Knoxville North

Days Inn by Wyndham Knoxville North
2.5 star property
3 km from North Knoxville Medical Center
7.0 out of 10, Good, (522)
"Quiet stay. Comfortable bed."
United States
Chris
The price is HK$415
HK$490 total
includes taxes & fees
28 Dec - 29 Dec
Days Inn by Wyndham Knoxville North
Blackout curtains, iron/ironing board, free cots/infant beds
Super 8 by Wyndham Knoxville North/Powell

Super 8 by Wyndham Knoxville North/Powell

Super 8 by Wyndham Knoxville North/Powell
2.0 star property
0.7 km from North Knoxville Medical Center
6.4 out of 10, (715)
"Tesla supercharger a short drive way. "
United States
Ian
The price is HK$496
HK$567 total
includes taxes & fees
30 Dec - 31 Dec
Super 8 by Wyndham Knoxville North/Powell
Restaurant
Tru by Hilton Knoxville North I75

Tru by Hilton Knoxville North I75

Tru by Hilton Knoxville North I75
2.5 star property
4.9 km from North Knoxville Medical Center
9.4 out of 10, Exceptional, (1006)
"Great hotel."
United States
Canay
The price is HK$734
HK$868 total
includes taxes & fees
29 Dec - 30 Dec
Tru by Hilton Knoxville North I75
Indoor pool
Hampton Inn & Suites-Knoxville/North I-75

Hampton Inn & Suites-Knoxville/North I-75

Hampton Inn & Suites-Knoxville/North I-75
2.5 star property
5 km from North Knoxville Medical Center
9.4 out of 10, Exceptional, (1002)
"Staff were very friendly! "
United States
Jennifer
The price is HK$893
HK$1,056 total
includes taxes & fees
2 Jan - 3 Jan 2026
Hampton Inn & Suites-Knoxville/North I-75
Lobby
Fairfield Inn & Suites by Marriott Knoxville Northwest

Fairfield Inn & Suites by Marriott Knoxville Northwest

Fairfield Inn & Suites by Marriott Knoxville Northwest
2.5 star property
5.1 km from North Knoxville Medical Center
9.4 out of 10, Exceptional, (450)
"Clean room, Good breakfast options, friendly staff."
United States
Lolak
The price is HK$801
HK$948 total
includes taxes & fees
28 Dec - 29 Dec
Fairfield Inn & Suites by Marriott Knoxville Northwest
Free daily buffet breakfast
Comfort Suites Knoxville North

Comfort Suites Knoxville North

Comfort Suites Knoxville North
2.5 star property
5 km from North Knoxville Medical Center
9.0 out of 10, Wonderful, (1000)
"Enjoyed our short stay. "
United States
Glen
The price is HK$722
HK$854 total
includes taxes & fees
11 Jan - 12 Jan 2026
Comfort Suites Knoxville North
Lobby
Spark by Hilton Knoxville North I-75

Spark by Hilton Knoxville North I-75

Spark by Hilton Knoxville North I-75
2.5 star property
5.2 km from North Knoxville Medical Center
8.8 out of 10, Excellent, (121)
"Fantastic stay! Room was very clean and the staff were so attentive and friendly. Would recommend staying here."
United States
rachel
The price is HK$568
HK$671 total
includes taxes & fees
2 Jan - 3 Jan 2026
Spark by Hilton Knoxville North I-75
Exterior
Holiday Inn Knoxville N - Merchant Drive by IHG

Holiday Inn Knoxville N - Merchant Drive by IHG

Holiday Inn Knoxville N - Merchant Drive by IHG
3.0 star property
5 km from North Knoxville Medical Center
8.8 out of 10, Excellent, (1000)
"Great place to stay"
United States
Charles
The price is HK$856
HK$1,012 total
includes taxes & fees
11 Jan - 12 Jan 2026
Holiday Inn Knoxville N - Merchant Drive by IHG
Lobby
Best Western Knoxville Suites - Downtown

Best Western Knoxville Suites - Downtown

Best Western Knoxville Suites - Downtown
2.5 star property
5.1 km from North Knoxville Medical Center
7.8 out of 10, Good, (1002)
"Clean hotel and room, great place to stay if you are in town for a Vols Game. "
United States
Jess
The price is HK$691
HK$818 total
includes taxes & fees
6 Jan - 7 Jan 2026
Best Western Knoxville Suites - Downtown
Desk, blackout curtains, iron/ironing board, free cots/infant beds
Red Roof Inn Knoxville North - Merchants Drive

Red Roof Inn Knoxville North - Merchants Drive

Red Roof Inn Knoxville North - Merchants Drive
2.0 star property
5.2 km from North Knoxville Medical Center
6.6 out of 10, (1008)
"Only minutes from downtown and UT. Also convenient to all major thoroughfares in and around Knoxville. "
United States
Jason D
The price is HK$537
HK$635 total
includes taxes & fees
24 Dec - 25 Dec
Red Roof Inn Knoxville North - Merchants Drive
Exterior
Super 8 by Wyndham Knoxville Downtown Area

Super 8 by Wyndham Knoxville Downtown Area

Super 8 by Wyndham Knoxville Downtown Area
2.0 star property
5.4 km from North Knoxville Medical Center
6.2 out of 10, (1003)
"Nice professional staff"
United States
Jacob
The price is HK$397
HK$469 total
includes taxes & fees
30 Dec - 31 Dec
Super 8 by Wyndham Knoxville Downtown Area
Exterior
Studio 6 Suites – Knoxville, TN

Studio 6 Suites – Knoxville, TN

Studio 6 Suites – Knoxville, TN
2.0 star property
5 km from North Knoxville Medical Center
6.4 out of 10, (576)
"If the lady at the front wasn't so nice i wouldn't have bothered checking in. "
United States
Cristina
The price is HK$512
HK$605 total
includes taxes & fees
24 Dec - 25 Dec
Studio 6 Suites – Knoxville, TN
Desk, blackout curtains, iron/ironing board, free cots/infant beds
Days Inn by Wyndham Knoxville East

Days Inn by Wyndham Knoxville East

Days Inn by Wyndham Knoxville East
3.0 star property
14.6 km from North Knoxville Medical Center
6.8 out of 10, (1113)
"Good hotel"
United States
Jonathan
The price is HK$456
HK$540 total
includes taxes & fees
28 Dec - 29 Dec
Days Inn by Wyndham Knoxville East
Hypo-allergenic bedding, pillow-top beds, individually decorated
MainStay Suites Knoxville North I-75

MainStay Suites Knoxville North I-75

MainStay Suites Knoxville North I-75
2.5 star property
5.3 km from North Knoxville Medical Center
7.6 out of 10, Good, (753)
"Very nice place to stay"
United States
Dorothy
The price is HK$623
HK$737 total
includes taxes & fees
1 Jan - 2 Jan 2026
MainStay Suites Knoxville North I-75
Indoor pool
Baymont by Wyndham Clinton

Baymont by Wyndham Clinton

Baymont by Wyndham Clinton
2.5 star property
14.5 km from North Knoxville Medical Center
6.8 out of 10, (1001)
"Rooms were decently clean and the staff was courteous. The pool area was decent. "
United States
Glynton
The price is HK$450
HK$530 total
includes taxes & fees
19 Jan - 20 Jan 2026
Baymont by Wyndham Clinton
Lobby
Quality Inn Merchants Drive

Quality Inn Merchants Drive

Quality Inn Merchants Drive
2.5 star property
5.1 km from North Knoxville Medical Center
7.0 out of 10, Good, (1002)
"Room was clean, staff was friendly and helpful"
United States
Amy
The price is HK$421
HK$498 total
includes taxes & fees
11 Jan - 12 Jan 2026
Quality Inn Merchants Drive
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top North Knoxville Medical Center Hotel Reviews

Comfort Suites Knoxville North

Comfort Suites Knoxville North

10/10 Excellent
"Excellent stay. We were greated by friendly faces which was so nice after driving for 11hrs. Our room was clean and all our toiletries were stocked. The pool was exceptional and we will definitely be back. This is our families favorite stop "
Danielle 1-night trip
Posted 19 hours ago
Comfort Suites Knoxville North

Hotels near other North Knoxville Medical Center attractions

Knoxville Zoo

4.3/5 (333 reviews)
Why not see the exotic and native animals who call Knoxville Zoo home during your holiday in Knoxville? Attend a sporting event or simply enjoy the lively bars while you're in the area.
See properties

Max Air Trampoline Park

You can take time to visit Max Air Trampoline Park during your travels to Powell. Attend a sporting event or simply enjoy the lively bars while you're in the area.
See properties

Frequently asked questions

What's the area like around North Knoxville Medical Center?
North Knoxville Medical Center is located in Powell. Travellers like this family-friendly area for its restaurants. If you're looking for a convenient place to stay, take a look at the 7 hotels and other accommodation options you'll find within a mile.
What's the best place to stay near North Knoxville Medical Center?
Adjacent to North Knoxville Medical Center, Comfort Inn Powell - Knoxville North is one of the top choices for your stay based on our traveller data, and this hotel offers free breakfast and an indoor pool. Other good choices within a short distance include Holiday Inn Express & Suites Knoxville-North-I-75 Exit 112 by IHG and La Quinta Inn & Suites by Wyndham Knoxville North I-75.
How many hotels are there close to North Knoxville Medical Center?
Expedia has 7 hotels and other accommodation options within a mile from North Knoxville Medical Center.
If I need to cancel the hotel reservation for my stay near North Knoxville Medical Center, will I receive a refund?
Yes! The majority of hotel bookings are refundable if you cancel before the accommodation's cancellation deadline, which often is within 24-48 hours of your arrival date. If you have a non-refundable reservation, you may still be able to cancel and receive a refund within 24 hours of booking. Put your dates in and click on "Search", then you can filter by "fully refundable" to view top deals close to North Knoxville Medical Center.