A calm river with clear water, surrounded by dense trees and rocky banks.

O Brien hotels from HK$427

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Our top choices for O Brien hotels

1. Hampton Inn & Suites Lake City

Hampton Inn & Suites Lake City
2.5 star property
Lake City
9.4 out of 10, Exceptional, (1,004 reviews)
"Every employee greeted us and asked how was our stay. Couldn’t have asked for a hotel staff to care for us any better."
United States
DeeAnn
The price is HK$815
HK$917 total
includes taxes & fees
9 Aug - 10 Aug
Hampton Inn & Suites Lake City

2. Best Western Plus Lake City

Best Western Plus Lake City
2.5 star property
Lake City
9.0 out of 10, Wonderful, (1,065 reviews)
"The breakfast was very good, bacon ,egg,potatoes,waffle mix,juices,cereal,room were clean staff was excellent."
United States
Glenda
The price is HK$708
HK$796 total
includes taxes & fees
22 Jul - 23 Jul
Best Western Plus Lake City

3. Comfort Suites Lake City

Comfort Suites Lake City
2.5 star property
Lake City
9.4 out of 10, Exceptional, (1,006 reviews)
"Great place to stop for the night, very clean and great breakfast"
United States
RAFI
The price is HK$769
HK$865 total
includes taxes & fees
3 Aug - 4 Aug
Comfort Suites Lake City

4. La Quinta Inn & Suite by Wyndham Lake City

La Quinta Inn & Suite by Wyndham Lake City
3.0 star property
Lake City
8.8 out of 10, Excellent, (1,133 reviews)
"Great stay"
United States
Priscilla J
The price is HK$720
HK$810 total
includes taxes & fees
2 Aug - 3 Aug
La Quinta Inn & Suite by Wyndham Lake City

5. Tru by Hilton Lake City

Tru by Hilton Lake City
2.5 star property
Lake City
9.2 out of 10, Wonderful, (1,003 reviews)
"Clean Rooms excellent staff good breakfast"
United States
James
The price is HK$786
HK$884 total
includes taxes & fees
9 Aug - 10 Aug
Tru by Hilton Lake City

6. Fairfield Inn & Suites Lake City

Fairfield Inn & Suites Lake City
3.0 star property
Lake City
9.0 out of 10, Wonderful, (257 reviews)
"Cleaned place, good staff, basic breakfast"
United States
Adoniram
The price is HK$768
HK$864 total
includes taxes & fees
2 Aug - 3 Aug
Fairfield Inn & Suites Lake City

7. Home2 Suites by Hilton Lake City

Home2 Suites by Hilton Lake City
3.0 star property
Lake City
9.4 out of 10, Exceptional, (804 reviews)
"Great place to stay we will be back soon. "
United States
William
The price is HK$959
HK$1,079 total
includes taxes & fees
9 Aug - 10 Aug
Home2 Suites by Hilton Lake City

8. Holiday Inn Express & Suites Live Oak by IHG

Holiday Inn Express & Suites Live Oak by IHG
2.5 star property
Live Oak
8.4 out of 10, Very good, (855 reviews)
"Great stay!"
United States
Wes
The price is HK$820
HK$901 total
includes taxes & fees
2 Aug - 3 Aug
Holiday Inn Express & Suites Live Oak by IHG

9. Holiday Inn & Suites Lake City by IHG

Holiday Inn & Suites Lake City by IHG
3.0 star property
Lake City
8.6 out of 10, Excellent, (1,005 reviews)
"Breakfast was nice, friendly staff, convenient location. Clean room"
United States
Renee
The price is HK$717
HK$807 total
includes taxes & fees
16 Aug - 17 Aug
Holiday Inn & Suites Lake City by IHG

10. Super 8 by Wyndham Lake City

Super 8 by Wyndham Lake City
2.0 star property
Lake City
7.4 out of 10, Good, (740 reviews)
"Comfortable beds, quiet, nice staff."
United States
Mari
The price is HK$513
HK$577 total
includes taxes & fees
23 Jul - 24 Jul
Super 8 by Wyndham Lake City

11. Americas Best Value Inn Lake City

Americas Best Value Inn Lake City
2.0 star property
Lake City
8.6 out of 10, Excellent, (1,003 reviews)
"Staff was friendly the room was clean."
United States
Lorena
The price is HK$480
HK$540 total
includes taxes & fees
3 Aug - 4 Aug
Americas Best Value Inn Lake City

12. Cindys Motel

Cindys Motel
2.5 star property
Mayo
8.8 out of 10, Excellent, (136 reviews)
"wonderful, quiet, a hide a way for a fun stay"
United States
Diane
The price is HK$688
HK$744 total
includes taxes & fees
29 Jul - 30 Jul
Cindys Motel

13. Quality Inn White Springs Suwanee

Quality Inn White Springs Suwanee
2.5 star property
White Springs
7.2 out of 10, Good, (687 reviews)
"Cheap and food enough"
United States
william
The price is HK$447
HK$492 total
includes taxes & fees
22 Jul - 23 Jul
Quality Inn White Springs Suwanee

14. Quality Inn Lake City

Quality Inn Lake City
2.5 star property
Lake City
8.0 out of 10, Very good, (1,002 reviews)
"Great breakfast; clean rooms; very friendly staff."
United States
Lucille
The price is HK$566
HK$637 total
includes taxes & fees
19 Aug - 20 Aug
Quality Inn Lake City

15. Courtyard By Marriott Lake City

Courtyard By Marriott Lake City
3.0 star property
Lake City
9.4 out of 10, Exceptional, (276 reviews)
"Had an amazing stay. The hotel was nice and clean and up to date."
United States
Mary Magdalene
The price is HK$910
HK$1,024 total
includes taxes & fees
9 Aug - 10 Aug
Courtyard By Marriott Lake City

16. The Blanche

The Blanche
2.0 star property
Lake City
9.4 out of 10, Exceptional, (198 reviews)
"Great property! Beautiful renovated!"
United States
Brandi
The price is HK$1,164
HK$1,310 total
includes taxes & fees
3 Aug - 4 Aug
The Blanche

17. Suwannee River Retreat: Pet Friendly, Private Dock

Suwannee River Retreat: Pet Friendly, Private Dock
3.0 star property
Branford
The price is HK$2,666
HK$4,905 total
includes taxes & fees
12 Aug - 13 Aug
Suwannee River Retreat: Pet Friendly, Private Dock

18. Days Inn by Wyndham Lake City I-75

Days Inn by Wyndham Lake City I-75
2.0 star property
Lake City
7.6 out of 10, Good, (1,004 reviews)
"Great for a short stay and clean"
United States
Brizheet
The price is HK$495
HK$557 total
includes taxes & fees
22 Jul - 23 Jul
Days Inn by Wyndham Lake City I-75

19. TownePlace Suites by Marriott Lake City

TownePlace Suites by Marriott Lake City
3.0 star property
Lake City
9.6 out of 10, Exceptional, (139 reviews)
"Wonderfully clean, everything you need on a trip is provided"
United States
Jennifer
The price is HK$1,011
HK$1,138 total
includes taxes & fees
26 Jul - 27 Jul
TownePlace Suites by Marriott Lake City

20. Regal Inn

Regal Inn
2.5 star property
Lake City
8.4 out of 10, Very good, (611 reviews)
"First I was not sure if we wanted to stay there, but our room was pretty nice, price was excellent every thing was very clean. Lady at the front desk was very nice."
United States
Samuel
The price is HK$486
HK$547 total
includes taxes & fees
30 Jul - 31 Jul
Regal Inn
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Learn more about O Brien

Escape to this rural Florida gem where the Suwannee River offers peaceful kayaking trips and fishing adventures. Nearby Spirit of the Suwannee Music Park hosts live concerts, while O'Brien's local farms welcome visitors for fresh produce and family-friendly activities.

A calm river surrounded by trees reflecting in the water.

Top O Brien Hotel Reviews

More cheap stays in O Brien

Frequently asked questions

Where is the best place to stay in O Brien?
Holiday Inn Express & Suites Alachua - Gainesville Area by IHG, located 29.9 mi (48.2 km) from the heart of O Brien, is a top choice for your stay, based on our traveller data. Two other options for your trip to the area are Best Western Plus Lake City and La Quinta Inn & Suite by Wyndham Lake City. See all available top hotels, or vacation rentals in O Brien.
What are some of the best holiday rentals that O Brien has to offer?
Royal Springs Riverfront Retreat on 3 acres, kayak/canoe, boat ramp, huge decks!: This highly rated holiday home rental in O Brien is located on the beach, and has a balcony, a garden and a BBQ to put you at ease in your new surroundings. It has 3 bedrooms, as well as a kitchen with a dishwasher, a fridge and a stovetop, so that you can cook with friends or family. You and your friends and family can relax into your holiday with amenities such as a selection of games. See all vacation rentals in O Brien.
If I need to cancel my hotel reservation in O Brien, will I receive a refund?
Yes! You'll find that most hotel bookings are refundable if you cancel before the hotel's cancellation deadline, which is usually within 24-48 hours of the scheduled arrival. If your reservation is non-refundable, you might be able to still cancel and receive a refund within 24 hours of booking. Filter your search by fully refundable to find flexible hotel deals in O Brien.
What are some accommodation options with pools in O Brien?
Holiday Inn Express & Suites Alachua - Gainesville Area by IHG: Provides buffet, an outdoor pool and complimentary high-speed (wired) Internet access. Royal Springs Riverfront Retreat on 3 acres, kayak/canoe, boat ramp, huge decks! and Little River Spring Cave divers poolside Hideaway are two additional hotels that feature an on-site pool. View all hotels with pools in O Brien.
How is it to stay in O Brien?
Visitors to O Brien will definitely find plenty to explore and enjoy. In O Brien, there are 9 hotels and other accommodation options to choose from. Find out more about O Brien.
What are the top places to visit in O Brien?
Natural beauty is on display at Suwannee River, Ichetucknee River and Ichetucknee Springs State Park. You'll also find Troy Spring State Park and Wes Skiles Peacock Springs State Park in the area. Take a look at what more there is to see and do in Expedia's O Brien guide.
What's the seasonal weather in O Brien?
The hottest months are usually July and August, with an average temperature of 27°C, while the coldest months are January and February, with an average of 14°C. Average annual precipitation for O Brien is 1278 mm.

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