Best Puxico Hotels in 2026 from HK$433 - Fully Refundable Options

A night scene with a clear sky, a crescent moon, and two silhouetted trees against a twilight sky.

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Our top choices for Puxico hotels

A modern lounge area with a stone fireplace, blue seating, a round coffee table, and a large window offering a view.

A reception area with a wooden counter, a coffee machine, and a display of pastries.

An outdoor patio with a table and chairs, a large umbrella, and a glass door leading to an interior space.

A corner market with a refrigerated display case and a pantry area.

1. Fairfield Inn & Suites by Marriott Poplar Bluff

Poplar Bluff

Arsenia

HK$793

HK$896 total

includes taxes & fees

30 Aug - 31 Aug

A spacious dining area with multiple tables and chairs, a flat-screen TV mounted on the wall, and large windows providing natural light.

2. Hampton Inn Poplar Bluff

Poplar Bluff

Philip

HK$733

HK$821 total

includes taxes & fees

13 Sept - 14 Sept

A spacious lobby with a reception desk, seating area, and large windows.

A spacious lobby with a high ceiling, a mezzanine level, and a seating area with a sofa and chairs.

An indoor swimming pool with a clear view of the outside through large windows.

A spacious conference room with brick walls, multiple tables and chairs, a large window, and a mounted TV.

3. Drury Inn & Suites Poplar Bluff

Poplar Bluff

Elaine

HK$737

HK$833 total

includes taxes & fees

13 Sept - 14 Sept

A modern hotel lobby with a bar area, seating, and artwork on the walls.

A swimming pool with clear blue water, surrounded by sun loungers and a lifeguard stand.

A reception desk with a wooden panel design, a white vase with flowers, and a 'Hilton HONOR' sign.

A modern hotel with a prominent sign, a covered entrance, and a well-lit exterior.

4. Hampton Inn By Hilton Dexter

Dexter

Joyce

HK$765

HK$859 total

includes taxes & fees

29 Aug - 30 Aug

A diner with booth seating, a checkered floor, and a counter with a cash register.

A lobby with a round rug, two potted plants, three framed artworks, and two black leather chairs.

A reception area with a marble counter, potted plants, a clock, and a TV on the wall.

A gym with multiple exercise machines, a clock on the wall, and a window with blinds.

5. Travelodge by Wyndham Dexter

Dexter

Steven

HK$684

HK$769 total

includes taxes & fees

23 Aug - 24 Aug

A modern kitchen with a coffee machine, a sink, and a counter. There are four chairs and a table in the dining area.

A compact kitchen with a dark wooden desk, a black refrigerator, a microwave, and a coffee maker.

A motel with a prominent '66' sign, large windows, and a flat roof.

A hotel room with two beds, a desk, a chair, a TV mounted on the wall, and a mirror.

6. Motel 6 Poplar Bluff, MO

Poplar Bluff

Kathleen

HK$619

HK$694 total

includes taxes & fees

22 Aug - 23 Aug

A coffee shop with a coffee machine, espresso cups, a sink, and a trash bin.

A kitchen with a white microwave, a fruit basket, a coffee maker, and a storage container.

A hotel hallway with patterned carpet, light green walls, and a ceiling with recessed lighting.

A hotel lobby with a reception desk, a waiting area with a sofa and armchairs, and a patterned carpet.

7. Dexter Inn

Dexter

Cynthia

HK$510

HK$572 total

includes taxes & fees

24 Aug - 25 Aug

A hotel room with a bed, a desk, a chair, a bathroom with a bathtub, and a patterned floor.

A hotel with a brick facade, multiple windows, and a covered entrance area.

A living room with a sofa, a coffee table, a clock, and a painting on the wall.

A kitchen with wooden cabinets, a stainless steel sink, a microwave, and a dishwasher.

8. Econo Lodge Dexter

Dexter

Herman

HK$400

HK$449 total

includes taxes & fees

19 Sept - 20 Sept

A spacious restaurant with wooden tables and benches, large windows, and a bar area.

A hotel lobby with a reception desk, seating area, and a patterned rug.

A modern lobby with a curved sectional sofa, two armchairs, a glass coffee table, and a patterned rug.

A bar area with wooden bar stools, a counter with a TV, and shelves stocked with bottles.

9. Holiday Inn Poplar Bluff by IHG

Poplar Bluff

Paige

HK$651

HK$735 total

includes taxes & fees

20 Sept - 21 Sept

A hotel lobby with a reception desk, a blue sofa, a fireplace, and a television.

A hotel lobby with a coffee station, seating area, and a television screen.

A hotel room with a bed, a sofa, a small table, and a painting on the wall.

A hotel room with a bed, two armchairs, a sofa, a small table, a TV, a ceiling fan, and a window with curtains.

10. Comfort Inn Poplar Bluff North

Poplar Bluff

Muhammad

HK$632

HK$714 total

includes taxes & fees

13 Sept - 14 Sept

A living room with a blue wall, a fireplace, a sofa, and a chair.

A sign for EC REED'S MERCANTILE & HOTEL with a geometric design.

A brick building with a sign reading "Mercantile & Hotel".

A bar area with stools and a counter where a bartender is serving drinks.

11. EC Reed's Mercantile and Hotel

Marble Hill

JANEEN

HK$791

HK$861 total

includes taxes & fees

22 Aug - 23 Aug

A hotel room with a bed, two bedside lamps, a framed picture of a building, and a nightstand with a phone.

A lobby with a reception desk, a Coca-Cola vending machine, a snack vending machine, and a seating area with a round table.

A self-service breakfast area with a refrigerated drink cooler, a coffee machine, and various food items on the counter.

A laundry area with two stacked washers and dryers, a control panel, and a beige wall with a wooden panel above the dryers.

12. Super 8 by Wyndham Poplar Bluff Missouri

Poplar Bluff

Diana

HK$433

HK$489 total

includes taxes & fees

12 Sept - 13 Sept

A rustic cabin with a metal roof, surrounded by a wooden deck and picnic tables, set in a forested area.

A calm lake with a wooden dock and a forested island in the distance.

A wooden deck with a railing leading to a building with a metal roof and a brown door.

A bedroom with a wooden bed, a bench, and a window.

13. Lake Wappapello

Williamsville

Tonya

HK$600

HK$633 total

includes taxes & fees

24 Aug - 25 Aug

A hotel room with two beds, a TV, a mirror, a wardrobe, and a desk.

A Hickory House Inn with a clear sky, a parking lot, and a covered entrance.

A bathroom with a bathtub, toilet, and a shower curtain.

A window with a view of a parking lot and buildings, a welcome sign, and a credit card machine.

14. OYO Hickory House Inn

Dexter

Tammy

HK$354

HK$433 total

includes taxes & fees

12 Sept - 13 Sept

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Learn more about Puxico

Head to sights like Mark Twain National Forest and Mingo Wilderness as you discover Puxico.

See all hotels in Puxico

Top Puxico Hotel Reviews

Drury Inn & Suites Poplar Bluff

10/10 Excellent

"Clean, relaxing room, great breakfast, friendly staff"

Fairfield Inn & Suites by Marriott Poplar Bluff

10/10 Excellent

"Great"

Econo Lodge Dexter

8/10 Good

"Quiet"

Hampton Inn By Hilton Dexter

10/10 Excellent

"Best Hampton Inn that I have ever stayed in. Excellent service and Wonderful staff. Extremely helpful with disabled husband."

EC Reed's Mercantile and Hotel

10/10 Excellent

"I loved how cute and well decorated everything was, from the room to the lobby area. Next time when we have more time, I hope to use the restaurant, shop, and ice cream! So yes, we will be back!"

Hampton Inn Poplar Bluff

10/10 Excellent

"Room was comfortable and clean."

Travelodge by Wyndham Dexter

10/10 Excellent

"It’s was clean and very well maintained"

Motel 6 Poplar Bluff, MO

8/10 Good

"Clean and nice."

Holiday Inn Poplar Bluff by IHG

10/10 Excellent

"Everything was amazing."

More cheap stays in Puxico

Super 8 by Wyndham Poplar Bluff Missouri

2831 N Westwood Blvd Poplar Bluff MO

HK$433

HK$489 total

12 Sept - 13 Sept

includes taxes & fees

Motel 6 Poplar Bluff, MO

4101 Highway 67 N Poplar Bluff MO

HK$619

HK$694 total

22 Aug - 23 Aug

includes taxes & fees

8/10 Very good! (1,005 reviews)

Comfort Inn Poplar Bluff North

2582 N Westwood Blvd Poplar Bluff MO

HK$632

HK$714 total

13 Sept - 14 Sept

includes taxes & fees

7.8/10 Good! (432 reviews)

Travelodge by Wyndham Dexter

1608 E Business US 60 Dexter MO

HK$684

HK$769 total

23 Aug - 24 Aug

includes taxes & fees

7.6/10 Good! (420 reviews)

Hampton Inn Poplar Bluff

2420 Crestwood Dr Poplar Bluff MO

HK$733

HK$821 total

13 Sept - 14 Sept

includes taxes & fees

9.4/10 Exceptional! (917 reviews)

Hampton Inn By Hilton Dexter

2179 Gill Plaza Drive Dexter MO

HK$765

HK$859 total

29 Aug - 30 Aug

includes taxes & fees

9.8/10 Exceptional! (66 reviews)

Frequently asked questions

What's the best place for a stay in Puxico?

Motel 6 Poplar Bluff, MO, located 19.4 mi (31.3 km) from the heart of Puxico, is a top choice for your stay, based on our traveller data. Other good options for your trip to the area are Fairfield Inn & Suites by Marriott Poplar Bluff and Drury Inn & Suites Poplar Bluff. See all available top hotels, or vacation rentals in Puxico.

What are some of the best holiday rentals that Puxico has to offer?

Private lake, beach & hot tub, romantic getaway or family vaca: This holiday home rental outside of Puxico is equipped with 1 hot tub, air conditioning and laundry facilities to help you feel comfortable during your stay. See all vacation rentals in Puxico.

If I need to cancel my hotel reservation in Puxico, will I receive a refund?

Yes, you'll find most hotel bookings are refundable provided that you cancel prior to the accommodation's cancellation deadline, which is usually within 24-48 hours of the scheduled arrival. If your reservation is non-refundable, it might still be possible to cancel it and be given a refund within a 24-hour period of booking. Filter your search by fully refundable to find flexible hotel deals in Puxico.

What is staying in Puxico like?

Travellers to Puxico will find plenty to explore and enjoy. There are 56 hotels and other accommodation options in the surrounding area. Find out more about Puxico.

What is there to see in Puxico?

A couple of favourite places to visit are Mark Twain National Forest and Mingo Wilderness. You'll also find Lake Wappapello and Lake Wappapello State Park in the area. Take a look at what more there is to see and do in Expedia's Puxico guide.

What's the seasonal weather in Puxico?

The hottest months are usually July and August, with an average temperature of 25°C, while the coldest months are January and February, with an average of 5°C. Average annual precipitation for Puxico is 1502 mm.

Puxico hotels from HK$433

Change your mind

Treat yourself

Be picky

Go beyond your typical stay in Puxico

Check prices for these dates

Filter by

Star rating

Guest rating

Our top choices for Puxico hotels

1. Fairfield Inn & Suites by Marriott Poplar Bluff

2. Hampton Inn Poplar Bluff

3. Drury Inn & Suites Poplar Bluff

4. Hampton Inn By Hilton Dexter

5. Travelodge by Wyndham Dexter

6. Motel 6 Poplar Bluff, MO

7. Dexter Inn

8. Econo Lodge Dexter

9. Holiday Inn Poplar Bluff by IHG

10. Comfort Inn Poplar Bluff North

11. EC Reed's Mercantile and Hotel

12. Super 8 by Wyndham Poplar Bluff Missouri

13. Lake Wappapello

14. OYO Hickory House Inn

Learn more about Puxico

Top Puxico Hotel Reviews

Drury Inn & Suites Poplar Bluff

Fairfield Inn & Suites by Marriott Poplar Bluff

Econo Lodge Dexter

Hampton Inn By Hilton Dexter

EC Reed's Mercantile and Hotel

Hampton Inn Poplar Bluff

Travelodge by Wyndham Dexter

Motel 6 Poplar Bluff, MO

Holiday Inn Poplar Bluff by IHG

More cheap stays in Puxico

Super 8 by Wyndham Poplar Bluff Missouri

Motel 6 Poplar Bluff, MO

Comfort Inn Poplar Bluff North

Travelodge by Wyndham Dexter

Hampton Inn Poplar Bluff

Hampton Inn By Hilton Dexter

Frequently asked questions

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