Serra Mesa hotels in San Diego
Change your mindBook hotels with free cancellation
Be pickySearch almost a million properties worldwide
Check prices for these dates
Our top choices for Serra Mesa hotels
1. Hampton Inn San Diego-Kearny Mesa
Hampton Inn San Diego-Kearny Mesa3.5 km from Serra Mesa
9.2 out of 10, Wonderful, (1,006 reviews)
"Great rooms, clean, good experience"
Heather
The price is HK$1,140
HK$1,308 total
includes taxes & fees
25 Aug - 26 Aug
2. DoubleTree by Hilton Hotel San Diego - Mission Valley
DoubleTree by Hilton Hotel San Diego - Mission Valley4.2 km from Serra Mesa
8.4 out of 10, Very good, (1,749 reviews)
"I will definitely coming to stay there"
Benedict
The price is HK$1,151
HK$1,323 total
includes taxes & fees
9 Aug - 10 Aug
3. Courtyard by Marriott San Diego Mission Valley/Hotel Circle
Courtyard by Marriott San Diego Mission Valley/Hotel Circle5.5 km from Serra Mesa
8.4 out of 10, Very good, (1,513 reviews)
"Very friendly employees, Elva very nice I travel with kids, great breakfast"
Elizabeth
The price is HK$1,060
HK$1,219 total
includes taxes & fees
23 Aug - 24 Aug
4. Hampton Inn & Suites San Diego Airport Liberty Station
Hampton Inn & Suites San Diego Airport Liberty Station10.6 km from Serra Mesa
9.2 out of 10, Wonderful, (1,702 reviews)
"Great clean hotel close to the airport. Would definitely stay again."
Aimee
The price is HK$1,299
HK$1,493 total
includes taxes & fees
23 Aug - 24 Aug
5. Holiday Inn Express San Diego Airport - Old Town by IHG
Holiday Inn Express San Diego Airport - Old Town by IHG7.9 km from Serra Mesa
9.2 out of 10, Wonderful, (1,082 reviews)
"Very good hotel at the price with good choice of breakfast."
Tirthankar
The price is HK$1,186
HK$1,363 total
includes taxes & fees
3 Aug - 4 Aug
6. Embassy Suites by Hilton San Diego La Jolla
Embassy Suites by Hilton San Diego La JollaUniversity City, 10.3 km from Serra Mesa
8.8 out of 10, Excellent, (1,988 reviews)
"Room was good, breakfast was awesome along with evening drinks."
Jagjit
The price is HK$1,537
HK$1,990 total
includes taxes & fees
9 Aug - 10 Aug
7. Lamplighter Inn & Suites at SDSU
Lamplighter Inn & Suites at SDSU8.4 km from Serra Mesa
9.0 out of 10, Wonderful, (1,446 reviews)
"Great stay"
Bernadette
The price is HK$1,351
HK$1,523 total
includes taxes & fees
17 Aug - 18 Aug
8. Town and Country San Diego
Town and Country San Diego5.3 km from Serra Mesa
8.6 out of 10, Excellent, (1,667 reviews)
"Great experience for a family trip!"
Cynthia
The price is HK$1,400
HK$1,880 total
includes taxes & fees
13 Aug - 14 Aug
9. Homewood Suites by Hilton San Diego Hotel Circle/SeaWorld Area
Homewood Suites by Hilton San Diego Hotel Circle/SeaWorld Area6.4 km from Serra Mesa
8.8 out of 10, Excellent, (1,665 reviews)
"It was great staying here second time we stay here and we love it"
Jose
The price is HK$1,397
HK$1,606 total
includes taxes & fees
23 Aug - 24 Aug
10. Pleasant Inn
Pleasant Inn4.8 km from Serra Mesa
8.6 out of 10, Excellent, (1,506 reviews)
"Good place to stay, nice and clean"
Sydney Reegan
The price is HK$733
HK$841 total
includes taxes & fees
9 Aug - 10 Aug
11. Hampton Inn San Diego/Mission Valley
Hampton Inn San Diego/Mission Valley6.4 km from Serra Mesa
8.6 out of 10, Excellent, (1,670 reviews)
"Great hotel!"
Julie
The price is HK$1,028
HK$1,182 total
includes taxes & fees
4 Aug - 5 Aug
12. Legacy Resort Hotel & Spa
Legacy Resort Hotel & Spa5.8 km from Serra Mesa
9.2 out of 10, Wonderful, (3,119 reviews)
"The hotel was nice & clean!"
Vanesa Janet
The price is HK$1,389
HK$1,597 total
includes taxes & fees
2 Aug - 3 Aug
13. Hilton Garden Inn San Diego Old Town/SeaWorld Area
Hilton Garden Inn San Diego Old Town/SeaWorld AreaOld Town San Diego, 7.4 km from Serra Mesa
8.8 out of 10, Excellent, (1,491 reviews)
"Clean room and easy parking"
Maribel
The price is HK$1,097
HK$1,261 total
includes taxes & fees
23 Aug - 24 Aug
14. HYATT house San Diego/Sorrento Mesa
HYATT house San Diego/Sorrento Mesa11.8 km from Serra Mesa
9.2 out of 10, Wonderful, (1,001 reviews)
"Very clean hotel, breakfast options were great, bar prices reasonable. Would stay here again."
Malia
The price is HK$1,271
HK$1,460 total
includes taxes & fees
16 Aug - 17 Aug
15. Country Inn & Suites by Radisson, San Diego North, CA
Country Inn & Suites by Radisson, San Diego North, CA11.7 km from Serra Mesa
9.0 out of 10, Wonderful, (1,576 reviews)
"Very nice - clean, quiet, good breakfast and very helpful staff."
Kimberly
The price is HK$1,260
HK$1,448 total
includes taxes & fees
9 Aug - 10 Aug
16. Best Western Seven Seas
Best Western Seven Seas5.3 km from Serra Mesa
8.0 out of 10, Very good, (3,730 reviews)
"Location was great for me and the breakfast was pretty good"
John
The price is HK$734
HK$844 total
includes taxes & fees
9 Aug - 10 Aug
17. Best Western Inn & Suites San Diego – Zoo/SeaWorld Area
Best Western Inn & Suites San Diego – Zoo/SeaWorld Area6.6 km from Serra Mesa
8.0 out of 10, Very good, (2,847 reviews)
"Staff was friendly and hotel service was great!"
Mike and Maria
The price is HK$1,185
HK$1,362 total
includes taxes & fees
9 Aug - 10 Aug
18. Holiday Inn Express Hotel & Suites San Diego-Sorrento Valley by IHG
Holiday Inn Express Hotel & Suites San Diego-Sorrento Valley by IHG11.7 km from Serra Mesa
8.8 out of 10, Excellent, (1,007 reviews)
"Good place for staying"
Wan Chi
The price is HK$1,032
HK$1,186 total
includes taxes & fees
23 Aug - 24 Aug
19. Best Western Plus Hacienda Hotel Old Town
Best Western Plus Hacienda Hotel Old TownOld Town San Diego, 7.6 km from Serra Mesa
8.4 out of 10, Very good, (2,083 reviews)
"The included breakfast buffet was a great perk and the staff were very friendly."
Allan
The price is HK$1,122
HK$1,290 total
includes taxes & fees
25 Aug - 26 Aug
20. Kings Inn San Diego
Kings Inn San Diego6 km from Serra Mesa
8.8 out of 10, Excellent, (3,745 reviews)
"Great place to stay"
Manuel
The price is HK$836
HK$959 total
includes taxes & fees
26 Aug - 27 Aug
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Where to stay in Serra Mesa
Find the best Serra Mesa areas for the activities you enjoy most.
Downtown San Diego
Known for its fantastic nightlife, fascinating museums and beautiful waterfront views, there's plenty to explore in Downtown San Diego. Top attractions like Petco Park and Port of San Diego are major draws. Catch the metro at Civic Center Station or Civic Center Station to see more of the city.
Pacific Beach
Relax in beachside cafés in the morning, surf clean breaks in the afternoon and dance with a youthful club crowd at night at this coastal San Diego strip.
Mission Beach
If you're spending some time in Mission Beach, Mission Beach and Mission Bay are top sights worth seeing.
Gaslamp Quarter
San Diego’s historic heart has shed its seedy past to emerge as one of the city’s premier dining, shopping and entertainment hubs.
Mission Bay
If you're spending some time in Mission Bay, Mission Bay and Ski Beach are top sights worth seeing.
