Gainesville Santa Fe Depot Museum Hotels: 2026 Limited-Time Hotel Deals @Expedia

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Our top choices for Santa Fe Depot Museum hotels

A two-story house with a swimming pool, outdoor furniture, and a well-maintained garden.

A two-story house with a tiled roof, multiple windows, and a front porch.

A beach with a sunset, waves, and a few trees and structures in the distance.

A wooden deck with a hot tub, outdoor furniture, and a welcome sign on a building.

1. The Lancaster Manor B&B

0.8 km from Santa Fe Depot Museum

Jeffrey

HK$1,630

HK$1,875 total

includes taxes & fees

20 Oct - 21 Oct

A modern hotel lobby with a wooden ceiling, a large TV, a sofa, a coffee table, and a patterned floor.

A modern hotel lobby with a wooden ceiling, a reception desk, a seating area with green sofas, and a visible kitchen in the background.

A hotel with a modern facade, a covered entrance, and a parking lot.

A swimming pool with clear lane markings, adjacent lounge chairs, and a tiled floor.

2. Fairfield Inn & Suites by Marriott Gainesville I-35

1.8 km from Santa Fe Depot Museum

BALTAZAR

HK$753

HK$866 total

includes taxes & fees

25 Oct - 26 Oct

A modern hotel room with a large bed, a desk, a chair, and a sofa.

A motel with a covered parking area and multiple cars parked.

A reception area with a Days Inn sign, a counter with a tiled backsplash, a television, and a coffee machine.

A gym with treadmills, elliptical machines, and weight machines.

3. Days Inn by Wyndham Gainesville

2.5 km from Santa Fe Depot Museum

Tina

HK$487

HK$560 total

includes taxes & fees

15 Nov - 16 Nov

A buffet with labeled containers of omelets and other dishes.

A lobby with a coffee table, armchairs, a sofa, and lamps.

A coffee station with two coffee machines and a variety of coffee pods and cups.

A Holiday Inn Express hotel with a covered entrance, multiple windows, and a brick facade.

4. Holiday Inn Express & Suites Gainesville by IHG

1.1 km from Santa Fe Depot Museum

Donna

HK$620

HK$713 total

includes taxes & fees

16 Nov - 17 Nov

A spacious living area with a sofa, a glass-top coffee table, a desk with a computer, and a magazine rack. There is a dining area with tables and chairs in the background.

A hotel room with two beds, a desk, a chair, a TV, and a large window with curtains.

A reception desk with a mosaic tile design, a framed welcome sign, and a small table with a blue sign.

A hotel hallway with carpeted floors, doors on both sides, and a ceiling with recessed lighting.

5. Super 8 by Wyndham Gainesville TX

2.7 km from Santa Fe Depot Museum

Sid

HK$542

HK$623 total

includes taxes & fees

19 Oct - 20 Oct

A large indoor swimming pool with clear views through tall windows, a lounge chair, and a table with chairs.

A hotel room with a large bed, wooden headboard, bedside tables, a desk with a chair, and a television.

A hotel kitchen with a central island, wooden cabinets, and a breakfast bar.

A reception desk with a sign reading "Comfort Suites." There are two digital kiosks and a reception counter.

6. Comfort Suites Gainesville

2.5 km from Santa Fe Depot Museum

Tammera

HK$558

HK$642 total

includes taxes & fees

25 Oct - 26 Oct

A kitchen with a countertop, a refrigerator, a ceiling fan, and a window.

A motel with a brick facade, a covered parking area, and a car parked in front.

A bedroom with a bed, a desk, a chair, an air conditioning unit, a door, and a window.

A small office with a desk, computer, chair, and a clock on the wall.

7. Budget Host Motel Gainesville

2.7 km from Santa Fe Depot Museum

Mark

HK$471

HK$542 total

includes taxes & fees

19 Oct - 20 Oct

A spacious living area with a stone accent wall, a brown sofa, and a kitchen in the background.

A laundry area with two washing machines and a dryer, a water fountain, and a sign indicating guest laundry hours.

A gazebo with a roof and open sides, surrounded by grass and trees.

A hotel room with two beds, a desk with a TV, a mirror, and a lamp.

8. Loyalty Inn Gainesville

3 km from Santa Fe Depot Museum

Jimmy

HK$367

HK$422 total

includes taxes & fees

22 Oct - 23 Oct

A hotel room with two beds, a desk with a chair, a television, and a minibar.

A breakfast bar with coffee machines, a refrigerator, and a seating area with a wooden table and chairs.

A modern lobby with a green leather sofa, a glass coffee table, and potted plants.

9. Quality Inn Gainesville

0.9 km from Santa Fe Depot Museum

Roxann

HK$432

HK$502 total

includes taxes & fees

19 Oct - 20 Oct

A hotel room with a bed, a desk with a computer, a TV, a microwave, and a refrigerator.

A modern lobby with a green sofa, blue armchairs, a glass coffee table, and potted plants.

A spacious dining area with multiple wooden tables and chairs, a counter with food service equipment, and large windows with blinds.

10. Suburban Studios Gainesville

0.9 km from Santa Fe Depot Museum

Lynzee

HK$388

HK$447 total

includes taxes & fees

25 Oct - 26 Oct

A rustic interior with wooden floors, hanging plants, and a rustic ceiling.

A wooden cabin with a porch, surrounded by trees and a garden with yellow flowers.

A rustic dining area with a stone fireplace, wooden ceiling, and a table set for dining.

A backyard with a swimming pool, a wooden pergola, and a stone patio.

11. Oak Meadow Ranch

15 km from Santa Fe Depot Museum

Isaac

HK$1,201

HK$1,768 total

includes taxes & fees

21 Oct - 22 Oct

A spacious living room with patterned sofas, a coffee table, and a flat-screen TV mounted on the wall.

A modern kitchen with a large island, bar stools, and a flat-screen TV.

A hotel room with two beds, a desk, a TV, and a window.

A reception area with a curved reception desk, a flat-screen TV mounted on the wall, and framed artwork above the desk.

12. Best Western Red River Inn & Suites

13.9 km from Santa Fe Depot Museum

Douglas

HK$753

HK$844 total

includes taxes & fees

1 Nov - 2 Nov

A spacious kitchen with checkered flooring, wooden cabinets, and various appliances.

A gym with treadmills, elliptical machines, and a weight bench.

A modern hotel room with a large bed, a desk, and a view of the cityscape.

A laundry area with a wall-mounted soap, bleach, and softener dispenser, a washing machine, and stacked dryers.

13. Hampton Inn & Suites Gainesville

6.4 km from Santa Fe Depot Museum

Charlie

HK$573

HK$661 total

includes taxes & fees

9 Nov - 10 Nov

A spacious lobby with a reception desk, a staircase, and seating area.

A hotel room with a large bed, two bedside lamps, a bathroom with a bathtub, and a large mirror.

A spacious lobby with a fireplace, patterned wallpaper, and modern seating arrangements.

A swimming pool with a metal railing, surrounded by lounge chairs and a door in the background.

14. La Quinta Inn & Suites by Wyndham Gainesville

5.7 km from Santa Fe Depot Museum

Lupe

HK$680

HK$798 total

includes taxes & fees

9 Nov - 10 Nov

A hotel room with two beds, each with a green headboard, white bedding, and red accents. There are abstract paintings on the wall above the beds.

A building with a sign reading "Lindsay Inn" and a covered entrance area with columns.

A bathroom with a toilet, a shower curtain, a towel rack with towels, and a toilet paper holder.

A small, modern room with a gray sofa, a green armchair, a bed with a red blanket, a white pillow, and a painting on the wall.

15. Lindsay Inn

7.9 km from Santa Fe Depot Museum

Tammera

HK$549

HK$615 total

includes taxes & fees

19 Oct - 20 Oct

A modern living room with a fireplace, two bean bag chairs, a television, and large windows with blinds.

A hotel room with a bed, a chair, a small table, and a bathroom with a sink and mirror.

A modern restaurant with a bar area, dark wooden flooring, and contemporary furniture.

A modern hotel lobby with dark wood flooring, comfortable seating, a flat-screen TV, and a reception desk.

16. Red River Inn And Suites

13.9 km from Santa Fe Depot Museum

Troy

HK$777

HK$870 total

includes taxes & fees

19 Oct - 20 Oct

A hotel room with a bed, bedside table, lamp, and a television on a dresser.

A kitchen with wooden cabinets, a black countertop, and a black rug.

A building with a covered entrance, a clock, and a sign with a flag.

A spacious lobby with a ceiling fan, a reception desk, a refrigerator, and a door leading to the outside.

17. OYO Hotel Valley View TX, I-35

16.5 km from Santa Fe Depot Museum

Brian

HK$479

HK$565 total

includes taxes & fees

3 Nov - 4 Nov

View all properties

Compare popular hotels close to Santa Fe Depot Museum

Property	Property class	Guest rating
The Lancaster Manor B&B	10.0 Exceptional 115 reviews	View
Fairfield Inn & Suites by Marriott Gainesville I-35	8.6 Excellent 1,001 reviews	View
Days Inn by Wyndham Gainesville	7.8 Good 1,002 reviews	View
Holiday Inn Express & Suites Gainesville by IHG	7.8 Good 1,001 reviews	View
Super 8 by Wyndham Gainesville TX	7.4 Good 1,000 reviews	View

Top Santa Fe Depot Museum Hotel Reviews

Comfort Suites Gainesville

8/10 Good

"2 of 3 ice machines out of order Room smelt musky At midnight a family with children running up & down the hall, opening & closing doors, making a lot of noise. Too tired to get out of bed to call front desk to complain!"

Best Western Red River Inn & Suites

10/10 Excellent

"The staff was helpful, friendly, and courteous. The lobby and common areas were clean and festively decorated. The room was clean and in good order. The breakfast was delicious."

Lindsay Inn

10/10 Excellent

"No breakfast, but room is clean and nice!! Modern bedding and furniture. Truly recommend staying here!! AA+"

Redbud Falls Ranch | Peaceful Horse Ranch Retreat & Private Horse Experiences

10/10 Excellent

"In town for a weddingEasy process and Melanie was very helpful making everything easy and smooth."

Loyalty Inn Gainesville

10/10 Excellent

"A nice peaceful place to stay. Good price."

Fairfield Inn & Suites by Marriott Gainesville I-35

8/10 Good

"Courtney at the front desk was awesome. Very helpful, friendly and nice. The chair in our room was very wobbly, she found us a replacement right away. The carpet had some spots on it, but the room had a couch and a desk and chair. It was noisy. The bed was clean and comfortable and the shower was great."

Oak Meadow Ranch

10/10 Excellent

"Amazing adventure! Book the Tranquility Cabin and the Serenity Slot experience! We’re still on a high from this experience! It was an absolutely amazing adventure that exceeded every single one of our expectations. The entire process was seamless and incredibly well-organized. The guides/hosts were phenomenally knowledgeable, patient, and full of infectious energy that made the day even more special. It balanced pure excitement with wonderful hospitality, leaving both of us completely captivated. It was genuinely a life-disrupting, beautiful memory that we will treasure forever. Don't even hesitate—just book it! For us, we’re looking forward to arranging to bring more family with us next time for a possible giraffe adventure! Thank you again Oak Meadow Ranch for such a one-a-lifetime adventure!"

Super 8 by Wyndham Gainesville TX

10/10 Excellent

"This is an older property but for the most part is nice, we felt safe. Really like the big fridge it kept our drinks very cold better than most motels. Only thing is all the road construction around the area. If you’re bougie this probably won’t be the place for you."

Budget Host Motel Gainesville

10/10 Excellent

"Every\nThing was excellent, clean room.Good parking , good air conditioner , nice staff"

Other attractions near Santa Fe Depot Museum

Cooke County Courthouse

7.6/10 (89 reviews)

After visiting Cooke County Courthouse, make a plan to see the other sights and activities in Gainesville. While you're in the area, find time to visit its casinos.

See properties

Depot Park

Depot Park is just one of the places to see in Gainesville, so why not enjoy the other things to explore during your travels? While in this family-friendly area, find time to visit its casinos.

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Butterfield Stage Players

7.2/10 (64 reviews)

You can enjoy a show at Butterfield Stage Players during your stay in Gainesville. While you're in the area, find time to visit its casinos.

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State Theater

7.4/10 (54 reviews)

You can enjoy a show at State Theater during your stay in Gainesville. While you're in the area, find time to visit its casinos.

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Morton Museum

7.2/10 (68 reviews)

You can spend time studying the exhibits at Morton Museum during your trip to Gainesville. While you're in the area, find time to visit its casinos.

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Tom Thumb Park

After visiting Tom Thumb Park, make a plan to see the other sights and activities in Gainesville. While in this family-friendly area, find time to visit its casinos.

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Jaycee Park

After visiting Jaycee Park, make a plan to see the other sights and activities in Gainesville. While in this family-friendly area, find time to visit its casinos.

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Gainesville War Memorial

8.0/10 (109 reviews)

Find out about the history of Gainesville with a stop at Gainesville War Memorial. While you're in the area, find time to visit its casinos.

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Frequently asked questions

What's the area like around Santa Fe Depot Museum?

Santa Fe Depot Museum is located in a welcoming area of Gainesville known for its first-class casinos. If you're looking for a convenient place to stay, take a look at the 17 hotels and other accommodation options you'll find within a mile.

What's the best place to stay near Santa Fe Depot Museum?

Quality Inn Gainesville is one of the top choices for your stay based on our traveller data, and this hotel offers free breakfast and free parking. It's located just a short 0.5 mi (0.9 km) from Santa Fe Depot Museum. Other good options within a short distance include Suburban Studios Gainesville and Holiday Inn Express Hotel & Suites Gainesville by IHG.

How many hotels are there near Santa Fe Depot Museum?

Expedia has 17 hotels and other accommodation options within a mile from Santa Fe Depot Museum.

If I need to cancel the hotel reservation for my stay near Santa Fe Depot Museum, will I receive a refund?

Yes! You'll find that most hotel reservations are fully refundable as long as you cancel before the hotel's cancellation deadline, which often is within 24-48 hours of check in. If you booked a non-refundable reservation, you might be able to cancel it and get a refund within a 24-hour period of booking. Enter your dates, click on "Search", then use the filter option "fully refundable" to review the best deals near Santa Fe Depot Museum.

What can I see and do near Santa Fe Depot Museum?

You can enjoy live performances at Butterfield Stage Players and State Theater. Get outside and spend some time strolling around Leonard Park, Tom Thumb Park and Jaycee Park. Gainesville War Memorial and Frank Buck Zoo are both worth a visit while you're out exploring.

Gainesville Santa Fe Depot Museum Hotels

Change your mind

Treat yourself

Be picky

Check prices for these dates

Filter by

Star rating

Guest rating

Our top choices for Santa Fe Depot Museum hotels

1. The Lancaster Manor B&B

2. Fairfield Inn & Suites by Marriott Gainesville I-35

3. Days Inn by Wyndham Gainesville

4. Holiday Inn Express & Suites Gainesville by IHG

5. Super 8 by Wyndham Gainesville TX

6. Comfort Suites Gainesville

7. Budget Host Motel Gainesville

8. Loyalty Inn Gainesville

9. Quality Inn Gainesville

10. Suburban Studios Gainesville

11. Oak Meadow Ranch

12. Best Western Red River Inn & Suites

13. Hampton Inn & Suites Gainesville

14. La Quinta Inn & Suites by Wyndham Gainesville

15. Lindsay Inn

16. Red River Inn And Suites

17. OYO Hotel Valley View TX, I-35

Compare popular hotels close to Santa Fe Depot Museum

Top Santa Fe Depot Museum Hotel Reviews

Comfort Suites Gainesville

Best Western Red River Inn & Suites

Lindsay Inn

Redbud Falls Ranch | Peaceful Horse Ranch Retreat & Private Horse Experiences

Loyalty Inn Gainesville

Fairfield Inn & Suites by Marriott Gainesville I-35

Oak Meadow Ranch

Super 8 by Wyndham Gainesville TX

Budget Host Motel Gainesville

Other attractions near Santa Fe Depot Museum

Cooke County Courthouse

Depot Park

Butterfield Stage Players

State Theater

Morton Museum

Tom Thumb Park

Jaycee Park

Gainesville War Memorial

Frequently asked questions