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Check prices for these dates

In two weeks
3 Jul - 5 Jul
In two months
14 Aug - 16 Aug
In three months
11 Sept - 13 Sept
In four months
9 Oct - 11 Oct

Our top choices for Sikeston holiday homes

Living area

Little Blue Cottage on Spanish

Little Blue Cottage on Spanish
Cape Girardeau
8.4 out of 10, Very good, (57 reviews)
"Great cute place. "
United States
Jeremy W.
The price is HK$635
HK$847 total
includes taxes & fees
19 Jun - 20 Jun
Little Blue Cottage on Spanish
Exterior

Dexter Victorian Homestead- Brand NEW Remodel April 2026. VERY Clean & Cozy

Dexter Victorian Homestead- Brand NEW Remodel April 2026. VERY Clean & Cozy
Dexter
7.8 out of 10, Good, (32 reviews)
"Stayed many times. Nice and comfortable "
United States
Susan R.
The price is HK$839
HK$1,683 total
includes taxes & fees
1 Jul - 2 Jul
Dexter Victorian Homestead- Brand NEW Remodel April 2026. VERY Clean & Cozy
Exterior

3+ acre Home: Pool Table, Putt-Putt, 4 miles to Downtown and SEMO, Summer Pool

3+ acre Home: Pool Table, Putt-Putt, 4 miles to Downtown and SEMO, Summer Pool
Cape Girardeau
8.8 out of 10, Excellent, (40 reviews)
"Will definitely book again! Great location, comfortable stay."
United States
Pynktoria !.
The price is HK$1,559
HK$2,634 total
includes taxes & fees
14 Jul - 15 Jul
3+ acre Home: Pool Table, Putt-Putt, 4 miles to Downtown and SEMO, Summer Pool
Pool

4-Bedroom Home - 2 King Beds, Summer Pool, Pool Table, Air Hockey + More

4-Bedroom Home - 2 King Beds, Summer Pool, Pool Table, Air Hockey + More
Cape Girardeau
9.6 out of 10, Exceptional, (9 reviews)
"Nice place, great times"
United States
Jace W.
The price is HK$2,938
HK$4,697 total
includes taxes & fees
14 Jul - 15 Jul
4-Bedroom Home - 2 King Beds, Summer Pool, Pool Table, Air Hockey + More
Property grounds

Brown's Lake House, Family-Friendly 2 Bedroom Retreat Near Lake Wappapello

Brown's Lake House, Family-Friendly 2 Bedroom Retreat Near Lake Wappapello
Wappapello
Brown's Lake House, Family-Friendly 2 Bedroom Retreat Near Lake Wappapello
Interior

Cozy and Updated Farmhouse with King Suite

Cozy and Updated Farmhouse with King Suite
Anna
10.0 out of 10, Exceptional, (19 reviews)
"Nice little house that was perfect for our family of five plus our dog. We would stay here again if we found ourselves out this way again."
United States
Kyle
The price is HK$698
HK$1,238 total
includes taxes & fees
21 Jun - 22 Jun
Cozy and Updated Farmhouse with King Suite
Interior

Charming 2-bedroom with AC, WiFi in lovely Jonesboro

Charming 2-bedroom with AC, WiFi in lovely Jonesboro
Jonesboro
10.0 out of 10, Exceptional, (9 reviews)
"It was a beautiful building and just what my sister in law needed to stay at after a local event. "
United States
Heather C.
The price is HK$909
HK$2,026 total
includes taxes & fees
19 Jun - 20 Jun
Charming 2-bedroom with AC, WiFi in lovely Jonesboro
Outdoor dining

Beautiful location in the secluded woods

Beautiful location in the secluded woods
Pomona
10.0 out of 10, Exceptional, (75 reviews)
"Easy access and beautiful location "
United States
Wilmer W.
The price is HK$879
HK$1,529 total
includes taxes & fees
29 Jun - 30 Jun
Beautiful location in the secluded woods
Outdoor spa tub

Retreat Air - King Bed, Hot Tub & No cleaning fee

Retreat Air - King Bed, Hot Tub & No cleaning fee
Perryville
10.0 out of 10, Exceptional, (6 reviews)
"Great host. Would stay again."
United States
Chris E.
The price is HK$1,097
HK$1,346 total
includes taxes & fees
18 Jul - 19 Jul
Retreat Air - King Bed, Hot Tub & No cleaning fee
Living area

Pa’s House is an enjoyable, entirely remodeled, 2-bedroom farmhouse near Anna.

Pa’s House is an enjoyable, entirely remodeled, 2-bedroom farmhouse near Anna.
Anna
10.0 out of 10, Exceptional, (3 reviews)
"Clean, attentive host, shops near by, family friendly "
United States
Molly J.
The price is HK$1,177
HK$2,369 total
includes taxes & fees
24 Jun - 25 Jun
Pa’s House is an enjoyable, entirely remodeled, 2-bedroom farmhouse near Anna.
Outdoor dining

Rendelman Orchard's Farm Stay

Rendelman Orchard's Farm Stay
Alto Pass
9.8 out of 10, Exceptional, (11 reviews)
"What an amazing spot! Perfect weekend getaway, close to several hikes in Shawnee and we enjoyed our time on the Rendleman Orchard. Came on a girls trip, but we agreed it would be a great spot for a weekend with our partners and kids. Will be back!"
United States
Julia S.
The price is HK$1,569
HK$1,968 total
includes taxes & fees
24 Jun - 25 Jun
Rendelman Orchard's Farm Stay
Outdoor dining

Walk to Weddings-Wineries-Trails, Family Friendly Home in Downtown Alto Pass

Walk to Weddings-Wineries-Trails, Family Friendly Home in Downtown Alto Pass
Alto Pass
10.0 out of 10, Exceptional, (3 reviews)
"The house was very welcoming and clean. Very inviting for our short stay. "
United States
brian O.
The price is HK$1,371
HK$2,055 total
includes taxes & fees
22 Jun - 23 Jun
Walk to Weddings-Wineries-Trails, Family Friendly Home in Downtown Alto Pass
Exterior

Magical Victorian near hiking / wine trail

Magical Victorian near hiking / wine trail
Anna
9.8 out of 10, Exceptional, (14 reviews)
"The house was beautiful! We were in awe of the decor and layout. This is a must-stay if you are in southern Illinois!"
United States
Lori C.
The price is HK$1,391
HK$2,746 total
includes taxes & fees
21 Jun - 22 Jun
Magical Victorian near hiking / wine trail
Exterior

Spacious 3-bedroom 2 story house in New Madrid near boat ramp with a toy room!

Spacious 3-bedroom 2 story house in New Madrid near boat ramp with a toy room!
New Madrid
10.0 out of 10, Exceptional, (1 review)
"The host was very quick to respond and so great to work with for on our stay. "
United States
Jessica S.
The price is HK$1,567
HK$2,892 total
includes taxes & fees
23 Jun - 24 Jun
Spacious 3-bedroom 2 story house in New Madrid near boat ramp with a toy room!
Fridge, microwave, oven, stovetop

Hunting / Fishing Cabin at Lake Wappapello

Hunting / Fishing Cabin at Lake Wappapello
Williamsville
The price is HK$1,448
HK$2,912 total
includes taxes & fees
20 Jun - 21 Jun
Hunting / Fishing Cabin at Lake Wappapello
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Sikeston Hotel Reviews

Drury Plaza Hotel Cape Girardeau Conference Center

Drury Plaza Hotel Cape Girardeau Conference Center

10/10 Excellent
"Drury is always a great stay. The amenities and staff are great and you get a lot of value for the cost of your stay."
Anthony 1-night trip
Posted 4 hours ago
Drury Plaza Hotel Cape Girardeau Conference Center

Find out more about Sikeston

Sikeston Vacation Homes information

Number of reviews
279
Accommodation
101 Vacation Homes
Lowest Price
HK$847
Highest Price
HK$4,697

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