Sikeston Holiday Rentals

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Check prices for these dates

In two weeks
12 Jun - 14 Jun
In two months
24 Jul - 26 Jul
In three months
21 Aug - 23 Aug
In four months
18 Sept - 20 Sept

Our top choices for Sikeston holiday rentals

1 bedroom, desk, iron/ironing board, WiFi

The Cottage, Rusted Route Farms

The Cottage, Rusted Route Farms
Jackson
10.0 out of 10, Exceptional, (2 reviews)
"This Cottage was very nice and clean and well maintained. The meat tray that we ordered and the breakfast tray was beyond Fabulous!!! My husband is still talking about it. . .Rick & Renee Christman"
United States
Renee C.
The price is HK$980
HK$1,544 total
includes taxes & fees
1 Jun - 2 Jun
The Cottage, Rusted Route Farms
Living area

Little Blue Cottage on Spanish

Little Blue Cottage on Spanish
Cape Girardeau
8.4 out of 10, Very good, (57 reviews)
"Great cute place. "
United States
Jeremy W.
The price is HK$635
HK$847 total
includes taxes & fees
7 Jun - 8 Jun
Little Blue Cottage on Spanish
TV, offices

Modern Boho Getaway · 1BR Apartment · By KeenStays

Modern Boho Getaway · 1BR Apartment · By KeenStays
Cape Girardeau
The price is HK$627
HK$1,310 total
includes taxes & fees
1 Jun - 2 Jun
Modern Boho Getaway · 1BR Apartment · By KeenStays
Exterior

Dexter Victorian Homestead- Brand NEW Remodel April 2026. VERY Clean & Cozy

Dexter Victorian Homestead- Brand NEW Remodel April 2026. VERY Clean & Cozy
Dexter
7.8 out of 10, Good, (31 reviews)
"Stayed many times. Nice and comfortable "
United States
Susan R.
The price is HK$839
HK$1,699 total
includes taxes & fees
2 Jun - 3 Jun
Dexter Victorian Homestead- Brand NEW Remodel April 2026. VERY Clean & Cozy
Desk, iron/ironing board, WiFi, bed sheets

Studio Apt | King Bed, Full Kitchen · By KeenStays

Studio Apt | King Bed, Full Kitchen · By KeenStays
Cape Girardeau
The price is HK$627
HK$1,310 total
includes taxes & fees
14 Jun - 15 Jun
Studio Apt | King Bed, Full Kitchen · By KeenStays
Interior

The Twisted Sassafras Treehouse

The Twisted Sassafras Treehouse
Cape Girardeau
10.0 out of 10, Exceptional, (34 reviews)
"Great location , great view, awesome place"
United States
Derek E.
The price is HK$1,686
HK$2,463 total
includes taxes & fees
3 Jun - 4 Jun
The Twisted Sassafras Treehouse
Interior

Enjoy easy access to everything from this centrally located place.

Enjoy easy access to everything from this centrally located place.
Dexter
The price is HK$635
HK$929 total
includes taxes & fees
8 Jun - 9 Jun
Enjoy easy access to everything from this centrally located place.
Dining

Serenity South -- Gardens, River-Views, and Refreshing Space

Serenity South -- Gardens, River-Views, and Refreshing Space
Cape Girardeau
10.0 out of 10, Exceptional, (156 reviews)
"Nice location to river front and downtown. Very lovely place."
United States
Marcie R.
The price is HK$1,175
HK$1,941 total
includes taxes & fees
1 Jun - 2 Jun
Serenity South -- Gardens, River-Views, and Refreshing Space
Interior

Charming Secluded Getaway Cabin within minutes of amenities

Charming Secluded Getaway Cabin within minutes of amenities
Cape girardeau
10.0 out of 10, Exceptional, (20 reviews)
"Nice little Cabin in a beautiful area. Blair and her family were wonderful!"
United States
Keegan C.
The price is HK$1,215
HK$2,403 total
includes taxes & fees
1 Jun - 2 Jun
Charming Secluded Getaway Cabin within minutes of amenities
Fridge, microwave, oven, stovetop

Relax in the country at Countryside Villas! - Villa A

Relax in the country at Countryside Villas! - Villa A
Jackson
10.0 out of 10, Exceptional, (34 reviews)
"Great place to stay, felt like home away from home. "
United States
Brittany
The price is HK$1,175
HK$1,407 total
includes taxes & fees
10 Jun - 11 Jun
Relax in the country at Countryside Villas! - Villa A
Interior

Villa B offers peace and quiet with beautiful views of the countryside.

Villa B offers peace and quiet with beautiful views of the countryside.
Jackson
10.0 out of 10, Exceptional, (12 reviews)
"It was great. "
United States
Benjamin Q.
The price is HK$1,175
HK$1,400 total
includes taxes & fees
30 Jun - 1 Jul
Villa B offers peace and quiet with beautiful views of the countryside.
Exterior

3+ acre Home: Pool Table, Putt-Putt, 4 miles to Downtown and SEMO, Summer Pool

3+ acre Home: Pool Table, Putt-Putt, 4 miles to Downtown and SEMO, Summer Pool
Cape Girardeau
8.8 out of 10, Excellent, (40 reviews)
"Will definitely book again! Great location, comfortable stay."
United States
Pynktoria !.
The price is HK$1,404
HK$2,447 total
includes taxes & fees
4 Jun - 5 Jun
3+ acre Home: Pool Table, Putt-Putt, 4 miles to Downtown and SEMO, Summer Pool
TV, fireplace

Gorgeous 1856 Log Cabin, Completely Renovated

Gorgeous 1856 Log Cabin, Completely Renovated
Jackson
10.0 out of 10, Exceptional, (3 reviews)
"incredible place. I was there for work, but it was a really nice relaxing area to retreat too, and also get some work done in a serene environment. It would be an incredible place for an entire family. And, a good place for friends to get together."
United States
Chandler G.
The price is HK$1,567
HK$2,422 total
includes taxes & fees
1 Jun - 2 Jun
Gorgeous 1856 Log Cabin, Completely Renovated
Pool

4-Bedroom Home - 2 King Beds, Summer Pool, Pool Table, Air Hockey + More

4-Bedroom Home - 2 King Beds, Summer Pool, Pool Table, Air Hockey + More
Cape Girardeau
9.6 out of 10, Exceptional, (9 reviews)
"Nice place, great times"
United States
Jace W.
The price is HK$2,645
HK$4,294 total
includes taxes & fees
4 Jun - 5 Jun
4-Bedroom Home - 2 King Beds, Summer Pool, Pool Table, Air Hockey + More
Interior

The Atrium - A Boutique Hotel

The Atrium - A Boutique Hotel
2.0 star property
Perryville
9.4 out of 10, Exceptional, (3 reviews)
"Very nice clean room with comfortable bed and nice shower. Kitchenette was good with microwave and mini fridge, basic dishes. The owner was very easy to communicate with. Good location with Mary Jane’s restaurant bar next door had excellent food and nice atmosphere. My only small suggestion would be to put variable light switches so you could turn down the lighting at night. I would definitely recommend and would stay here again on my next trip to Perryville."
United States
James
The price is HK$578
HK$1,233 total
includes taxes & fees
2 Jun - 3 Jun
The Atrium - A Boutique Hotel
Exterior

Winetrail Cabin - SIU, Giant City SP, Shawnee Forest, & Cedar Lake minutes away!

Winetrail Cabin - SIU, Giant City SP, Shawnee Forest, & Cedar Lake minutes away!
Makanda
9.8 out of 10, Exceptional, (48 reviews)
"Easily the best cabin experience I’ve ever had! Wonderful amenities everything we needed for a nice weekend stay was there and ready when we got there. Very comfortable space with plenty of room perfect destination for a small family get away will be returning soon thanks Steve!"
United States
Justin
The price is HK$940
HK$1,773 total
includes taxes & fees
2 Jun - 3 Jun
Winetrail Cabin - SIU, Giant City SP, Shawnee Forest, & Cedar Lake minutes away!
Exterior detail

3 Minutes to Giant City - 6 Minutes to SIU - 4 Minutes to Shawnee Winetrail!

3 Minutes to Giant City - 6 Minutes to SIU - 4 Minutes to Shawnee Winetrail!
Makanda
9.8 out of 10, Exceptional, (66 reviews)
"A nice quiet stay in the Shawnee Forest. Host was easy to communicate with and the cabin had everything we needed for a nice get away. Close to nature or close to shopping and dinner. It was the perfect little spot "
United States
Ruth O.
The price is HK$807
HK$1,497 total
includes taxes & fees
30 Jun - 1 Jul
3 Minutes to Giant City - 6 Minutes to SIU - 4 Minutes to Shawnee Winetrail!
Exterior

Rest, Relax and Renew. Our log cabin experience awaits your arrival.

Rest, Relax and Renew. Our log cabin experience awaits your arrival.
Anna
10.0 out of 10, Exceptional, (411 reviews)
"Great location. Cozy cabin. Would stay there again. "
United States
jeffrey s
The price is HK$917
HK$1,586 total
includes taxes & fees
1 Jun - 2 Jun
Rest, Relax and Renew. Our log cabin experience awaits your arrival.
Front of property

Pet Friendly! Countryside Couples Stay in Illinois

Pet Friendly! Countryside Couples Stay in Illinois
2.5 star property
Murphysboro
The price is HK$768
HK$1,866 total
includes taxes & fees
1 Jun - 2 Jun
Pet Friendly! Countryside Couples Stay in Illinois
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Sikeston Hotel Reviews

Best Western Plus Sikeston I-55

Best Western Plus Sikeston I-55

10/10 Excellent
"I always enjoy staying there when I go visit my kids and grandbabies. I usually rent a room so the grandbabies can swim."
Amy 2-night trip
Posted 1 hour ago
Best Western Plus Sikeston I-55

Find out more about Sikeston

Search for holiday rentals in Sikeston on Expedia! You can easily find your home rentals, villas, holiday apartments in Sikeston using one of the methods below:

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Frequently asked questions

Can I find a holiday rental in Sikeston?

Yes, there are holiday rentals close to the most popular sights in Sikeston, or you can select a more secluded option if you're looking for a relaxing stay. Tourists like the array of shops and top-notch restaurants in Sikeston. Make sure you allow time to enjoy the riverfront during your holiday.

What are some of the best holiday rentals that Sikeston has to offer?

Beautiful location in the secluded woods : This holiday home rental outside of Sikeston offers a fireplace, a patio and a BBQ to help you feel perfectly comfortable in your new surroundings. It has 3 bedrooms, as well as a kitchen with a dishwasher, a fridge and a stovetop, so that you can cook with friends or family. Make the most of games in this rental home to help you unwind.

What’s there to see and do in Sikeston?

Cultural attractions include Sikeston Depot Museum, whereas Central Park is a spot to enjoy nature. In the wider area, you’ll find River Ridge Winery and Front Street Studio & Art Gallery.

What’s a holiday rental in Sikeston like?

Holiday rentals are private properties where you can stay for a few weeks, or just a few days, in Sikeston. Holiday rentals offer amenities such as WiFi and washers and dryers so you'll be comfy for your stay. If you're concerned about a clean environment, a holiday rental can offer a sense of security away from public hotel lifts and bustling concierge desks while still allowing you a great travel experience. You'll also find more space in a holiday rental than in a hotel, which is another reason why a holiday rental is a popular option for family gatherings.