Photo by Bill Dillard

Southeast Missouri hotels from HK$426

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Go beyond your typical stay in Southeast Missouri

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Our top choices for Southeast Missouri hotels

1. Shepherd Mountain Inn

Shepherd Mountain Inn
2.5 star property
Ironton
9.2 out of 10, Wonderful, (338 reviews)
"Clean room, wifi easy to connect to, parking right in front."
United States
Jonathan
The price is HK$967
HK$1,056 total
includes taxes & fees
10 Nov - 11 Nov
Shepherd Mountain Inn

2. Madison Inn Lodge

Madison Inn Lodge
2.5 star property
Fredericktown
7.6 out of 10, Good, (314 reviews)
"Nice and clean friendly staff"
United States
Bawan
The price is HK$666
HK$728 total
includes taxes & fees
10 Nov - 11 Nov
Madison Inn Lodge

3. Hampton Inn & Suites By Hilton Festus

Hampton Inn & Suites By Hilton Festus
Festus
9.4 out of 10, Exceptional, (26 reviews)
"This was a wonderful hotel and had a wonderful stay. Room was clean and staff was wonderful."
United States
Misty
The price is HK$874
HK$1,000 total
includes taxes & fees
15 Nov - 16 Nov
Hampton Inn & Suites By Hilton Festus

4. Holiday Inn Express & Suites Farmington by IHG

Holiday Inn Express & Suites Farmington by IHG
2.5 star property
Farmington
8.6 out of 10, Excellent, (445 reviews)
"We stayed one night and it was great! Breakfast was delicious."
United States
January
The price is HK$894
HK$1,033 total
includes taxes & fees
22 Nov - 23 Nov
Holiday Inn Express & Suites Farmington by IHG

5. Hampton Inn Farmington

Hampton Inn Farmington
2.5 star property
Farmington
8.8 out of 10, Excellent, (582 reviews)
"The staff were so friendly & housekeeping came in each day to take care of our room. The breakfast was one of the best we have had. We had a great stay. Thank you to the staff!"
United States
Charlie
The price is HK$806
HK$922 total
includes taxes & fees
20 Nov - 21 Nov
Hampton Inn Farmington

6. Baymont Inn and Suites by Wyndham Farmington, MO

Baymont Inn and Suites by Wyndham Farmington, MO
2.5 star property
Farmington
8.0 out of 10, Very good, (1,003 reviews)
"Our room was spacious, clean and the bed was super comfortable!"
Canada
Kim
The price is HK$426
HK$488 total
includes taxes & fees
16 Nov - 17 Nov
Baymont Inn and Suites by Wyndham Farmington, MO

7. Super 8 by Wyndham Farmington

Super 8 by Wyndham Farmington
2.0 star property
Farmington
8.0 out of 10, Very good, (690 reviews)
"Clean nice staff are great"
United States
Marisa
The price is HK$467
HK$534 total
includes taxes & fees
16 Nov - 17 Nov
Super 8 by Wyndham Farmington

8. Fort Davidson Hotel

Fort Davidson Hotel
2.5 star property
Ironton
9.2 out of 10, Wonderful, (190 reviews)
"Clean rooms , nice pool."
United States
richard
The price is HK$941
HK$1,028 total
includes taxes & fees
17 Nov - 18 Nov
Fort Davidson Hotel

9. Fairfield Inn & Suites by Marriott Sikeston

Fairfield Inn & Suites by Marriott Sikeston
3.0 star property
Sikeston
9.4 out of 10, Exceptional, (118 reviews)
"Friendly staff, great breakfast, nice amenities"
United States
Roslyn
The price is HK$792
HK$900 total
includes taxes & fees
15 Nov - 16 Nov
Fairfield Inn & Suites by Marriott Sikeston

10. Fairfield Inn & Suites by Marriott Poplar Bluff

Fairfield Inn & Suites by Marriott Poplar Bluff
3.0 star property
Poplar Bluff
9.4 out of 10, Exceptional, (977 reviews)
"Everything was great- breakfast, cleanliness, price— will stay there again"
United States
ELAINE
The price is HK$760
HK$858 total
includes taxes & fees
22 Nov - 23 Nov
Fairfield Inn & Suites by Marriott Poplar Bluff

11. Crown Pointe Lodge, BW Signature Collection

Crown Pointe Lodge, BW Signature Collection
2.5 star property
Farmington
8.8 out of 10, Excellent, (702 reviews)
"Tucked away gem."
United States
christopher
The price is HK$793
HK$907 total
includes taxes & fees
19 Nov - 20 Nov
Crown Pointe Lodge, BW Signature Collection

12. Drury Inn & Suites Poplar Bluff

Drury Inn & Suites Poplar Bluff
3.0 star property
Poplar Bluff
9.4 out of 10, Exceptional, (1,001 reviews)
"Clean, great food, excellent staff."
United States
Dean
The price is HK$706
HK$797 total
includes taxes & fees
15 Nov - 16 Nov
Drury Inn & Suites Poplar Bluff

13. Drury Plaza Hotel Cape Girardeau Conference Center

Drury Plaza Hotel Cape Girardeau Conference Center
3.0 star property
Cape Girardeau
9.6 out of 10, Exceptional, (1,004 reviews)
"Easy check in and room was very clean. The food for breakfast and dinner is the bomb."
United States
Melody
The price is HK$784
HK$884 total
includes taxes & fees
13 Nov - 14 Nov
Drury Plaza Hotel Cape Girardeau Conference Center

14. Holiday Inn Express & Suites Perryville by IHG

Holiday Inn Express & Suites Perryville by IHG
2.5 star property
Perryville
9.2 out of 10, Wonderful, (645 reviews)
"Excellent stay , couldn't believe the property was 10 years old , it looks like it was just built , great place , highly recommend ."
United States
allan p.
The price is HK$792
HK$906 total
includes taxes & fees
15 Nov - 16 Nov
Holiday Inn Express & Suites Perryville by IHG

15. TownePlace Suites by Marriott Sikeston

TownePlace Suites by Marriott Sikeston
3.0 star property
Sikeston
9.2 out of 10, Wonderful, (31 reviews)
"I liked the lobby, bar and breakfast areas. The full breakfast buffet was awesome. Super nice room with kitchenette. Staff were great."
United States
Mark
The price is HK$826
HK$940 total
includes taxes & fees
15 Nov - 16 Nov
TownePlace Suites by Marriott Sikeston

16. Super 8 by Wyndham Perryville

Super 8 by Wyndham Perryville
2.0 star property
Perryville
8.6 out of 10, Excellent, (1,006 reviews)
"Nice room, friendly staff."
United States
Matthew
The price is HK$540
HK$618 total
includes taxes & fees
1 Dec - 2 Dec
Super 8 by Wyndham Perryville

17. La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau

La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau
3.0 star property
Jackson
8.8 out of 10, Excellent, (895 reviews)
"Very clean and every one very nice and helpful"
United States
richard
The price is HK$626
HK$678 total
includes taxes & fees
12 Nov - 13 Nov
La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau

18. EC Reed's Mercantile and Hotel

EC Reed's Mercantile and Hotel
3.0 star property
Marble Hill
9.4 out of 10, Exceptional, (118 reviews)
"Awesome hotel and staff was first rate, everything was fantastic. If you are in the area, stay at this hotel and eat in!!"
United States
Jan
The price is HK$824
HK$897 total
includes taxes & fees
15 Nov - 16 Nov
EC Reed's Mercantile and Hotel

19. Fairfield Inn & Suites by Marriott Cape Girardeau

Fairfield Inn & Suites by Marriott Cape Girardeau
3.0 star property
Cape Girardeau
9.4 out of 10, Exceptional, (242 reviews)
"Everything is very clean. Excellent facility all around. Friendly staff"
United States
Dane
The price is HK$793
HK$895 total
includes taxes & fees
15 Nov - 16 Nov
Fairfield Inn & Suites by Marriott Cape Girardeau

20. La Quinta Inn & Suites by Wyndham Festus - St. Louis South

La Quinta Inn & Suites by Wyndham Festus - St. Louis South
3.0 star property
Festus
7.8 out of 10, Good, (1,005 reviews)
"Nice breakfast. The hotel is a little worn but clean and comfortable."
United States
Julie
The price is HK$660
HK$754 total
includes taxes & fees
12 Nov - 13 Nov
La Quinta Inn & Suites by Wyndham Festus - St. Louis South
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Hotels recommended for families in Southeast Missouri

Stay near popular Southeast Missouri attractions

Learn more about Southeast Missouri

Discover the family-friendly area of Southeast Missouri—wineries, a scenic riverfront and sights from K Bridge Recreation Area to Lake Wappapello State Park.

A historical marker sign for the Frisco Depot, detailing its construction in 1928, architectural style, and historical significance.
Photo by Bill Dillard
Open Photo by Bill Dillard

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