
Southeast Missouri hotels from HK$433
- Change your mindBook hotels with free cancellation
- Be pickySearch almost a million properties worldwide
Go beyond your typical stay in Southeast Missouri
Cabin
Family friendly
Check prices for these dates
Our top choices for Southeast Missouri hotels

Drury Inn & Suites Sikeston, MO
Drury Inn & Suites Sikeston, MOSikeston
9.6 out of 10, Exceptional, (1,002 reviews)
The price is HK$831
HK$956 total
includes taxes & fees
2 Jul - 3 Jul

Drury Plaza Hotel Cape Girardeau Conference Center
Drury Plaza Hotel Cape Girardeau Conference CenterCape Girardeau
9.6 out of 10, Exceptional, (1,005 reviews)
The price is HK$784
HK$885 total
includes taxes & fees
12 Jul - 13 Jul

Fairfield Inn & Suites by Marriott Poplar Bluff
Fairfield Inn & Suites by Marriott Poplar BluffPoplar Bluff
9.4 out of 10, Exceptional, (925 reviews)
The price is HK$792
HK$895 total
includes taxes & fees
12 Jul - 13 Jul

Holiday Inn Express & Suites Sikeston Southwest by IHG
Holiday Inn Express & Suites Sikeston Southwest by IHGSikeston
8.6 out of 10, Excellent, (472 reviews)
The price is HK$823
HK$932 total
includes taxes & fees
26 Jul - 27 Jul

Hampton Inn Poplar Bluff
Hampton Inn Poplar BluffPoplar Bluff
9.4 out of 10, Exceptional, (879 reviews)
The price is HK$765
HK$857 total
includes taxes & fees
12 Jul - 13 Jul

Hampton Inn Sikeston
Hampton Inn SikestonSikeston
9.0 out of 10, Wonderful, (581 reviews)
The price is HK$797
HK$903 total
includes taxes & fees
19 Jul - 20 Jul

La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau
La Quinta Inn & Suites by Wyndham Jackson/Cape GirardeauJackson
9.0 out of 10, Wonderful, (788 reviews)
The price is HK$726
HK$786 total
includes taxes & fees
30 Jun - 1 Jul

Fairfield Inn & Suites by Marriott Cape Girardeau
Fairfield Inn & Suites by Marriott Cape GirardeauCape Girardeau
9.4 out of 10, Exceptional, (203 reviews)
The price is HK$727
HK$820 total
includes taxes & fees
9 Jul - 10 Jul

Courtyard by Marriott Cape Girardeau Downtown
Courtyard by Marriott Cape Girardeau DowntownCape Girardeau
9.6 out of 10, Exceptional, (525 reviews)
The price is HK$1,087
HK$1,232 total
includes taxes & fees
26 Jul - 27 Jul

Pear Tree Inn Cape Girardeau West
Pear Tree Inn Cape Girardeau WestCape Girardeau
9.0 out of 10, Wonderful, (1,000 reviews)
The price is HK$565
HK$637 total
includes taxes & fees
26 Jul - 27 Jul

Drury Inn & Suites Jackson MO
Drury Inn & Suites Jackson MOJackson
9.6 out of 10, Exceptional, (1,002 reviews)
The price is HK$643
HK$680 total
includes taxes & fees
26 Jul - 27 Jul

Super 8 by Wyndham Perryville
Super 8 by Wyndham PerryvillePerryville
8.4 out of 10, Very good, (1,001 reviews)
The price is HK$553
HK$633 total
includes taxes & fees
13 Jul - 14 Jul

Crown Pointe Lodge, BW Signature Collection
Crown Pointe Lodge, BW Signature CollectionFarmington
9.0 out of 10, Wonderful, (635 reviews)
The price is HK$860
HK$936 total
includes taxes & fees
19 Jul - 20 Jul

Holiday Inn Express & Suites Perryville by IHG
Holiday Inn Express & Suites Perryville by IHGPerryville
9.2 out of 10, Wonderful, (599 reviews)
The price is HK$862
HK$987 total
includes taxes & fees
3 Jul - 4 Jul

The Riverview
The RiverviewCape Girardeau
9.4 out of 10, Exceptional, (611 reviews)
The price is HK$1,037
HK$1,170 total
includes taxes & fees
1 Jul - 2 Jul

Hampton Inn Cape Girardeau I 55 East
Hampton Inn Cape Girardeau I 55 EastCape Girardeau
9.6 out of 10, Exceptional, (825 reviews)
The price is HK$830
HK$936 total
includes taxes & fees
12 Jul - 13 Jul

Tru By Hilton Cape Girardeau
Tru By Hilton Cape GirardeauCape Girardeau
9.6 out of 10, Exceptional, (140 reviews)
The price is HK$701
HK$798 total
includes taxes & fees
5 Jul - 6 Jul

Fairfield Inn & Suites by Marriott Sikeston
Fairfield Inn & Suites by Marriott SikestonSikeston
9.4 out of 10, Exceptional, (96 reviews)
The price is HK$792
HK$897 total
includes taxes & fees
5 Jul - 6 Jul

La Quinta Inn & Suites by Wyndham Festus - St. Louis South
La Quinta Inn & Suites by Wyndham Festus - St. Louis SouthFestus
7.8 out of 10, Good, (1,001 reviews)
The price is HK$699
HK$799 total
includes taxes & fees
29 Jun - 30 Jun

Deerfield Inn & Suites Steele Near Blytheville I 55
Deerfield Inn & Suites Steele Near Blytheville I 55Steele
The price is HK$377
HK$436 total
includes taxes & fees
28 Jun - 29 Jun
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Holiday Rentals in Southeast Missouri
Cabin

Postcard Cabins St Francois, Outdoor Collection by Marriott Bonvoy
Postcard Cabins St Francois, Outdoor Collection by Marriott BonvoyFrench Village
9.8 out of 10, Exceptional, (80 reviews)
Save an average of 15% on thousands of hotels when you're signed in
Stay near popular Southeast Missouri attractions
Learn more about Southeast Missouri
Discover the family-friendly area of Southeast Missouri—wineries, a scenic riverfront and sights from Walnut Hollow Lake to K Bridge Recreation Area.

Photo by Bill Dillard
Open Photo by Bill Dillard
More cheap stays in Southeast Missouri

Baymont Inn and Suites by Wyndham Farmington, MO
1625 W Columbia St Farmington MO
The price is HK$496 per night from 26 Jul to 27 Jul
HK$496
HK$539 total
26 Jul - 27 Jul
includes taxes & fees
8/10 Very good! (1,005 reviews)
Hotels in Southeast Missouri with star-rating

4 Star Hotels
1 properties
Explore a world of travel with Expedia
- 4 Star Hotels in Cadet
- Black Hotels
- Hilton Hotels in New Offenburg
- Vacation Homes in Qulin
- Motels in Ellington
- Bar Hotel Hotels in Poplar Bluff
- Cabin Rentals in Cadet
- Scott County Hotels
- Motels in Oran
- Cheap Hotels in Sikeston
- B&B in Middle Brook
- Hotels near Elephant Rocks State Park
- 5 Star Hotels in Oran
- Hotels near Missouri Mines State Historic Site
- Bunker Hotels
- Cabin Rentals in Sikeston
- Hotels near K Bridge Recreation Area
- Historic Hotel Hotels in Southeast Missouri
- Hotels near eDen Spa & Salon
- Hotel with Pool Hotels in Bonne Terre
- Fredericktown Hotels
- Valles Mines Hotels
- B&B in Black
- Drury Inn & Suites Hotels in Sikeston
- Cabin Rentals in Wappapello
- Motels in Fredericktown
- Apartments in Ste Genevieve
- Desloge Hotels
- Apartments in Arcadia
- 4 Star Hotels in Potosi
- Apartments in Farmington
- 4 Star Hotels in Oran
- Hotels near Echo Bluff State Park
- Hotels near Silver Mine Recreation Area
- Bar Hotel Hotels in Ste Genevieve
- Spa Hotel Hotels in De Soto
- Independent Hotels in Qulin
- Qulin Hotels
- Oran Hotels
- Cabin Rentals in Qulin
- Annapolis Hotels
- Hotels near Dillard Mill State Historic Site
- Spa Hotel Hotels in Southeast Missouri
- Romantic Hotel Hotels in Southeast Missouri
- Hotels near Hawn State Park
- Hotels near Felix Valle House State Historic Site
- Lodges in Eminence
- Hotels near National Shrine of Our Lady of the Miraculous Medal
- Cabin Rentals in Annapolis
- Poplar Bluff Hotels
- Hotels near Trail of Tears State Park
- Hotels near Taum Sauk Mountain State Park
- Pet-Friendly Hotel Hotels in Farmington
- 3 Star Hotels in Valles Mines
- Pet-Friendly Hotel Hotels in Poplar Bluff
- Cabin Rentals in Doniphan
- Hotels near St. Francois State Park
- Winery Hotel Hotels in Ste Genevieve
- Dexter Hotels
- Cabin Rentals in Poplar Bluff
- 5 Star Hotels in Leadwood
- Hotels near Powder Mill Cave Natural Area
- Farmington Hotels
- Pet-Friendly Hotel Hotels in Dexter
- Tiff Hotels
- Cottages in New Offenburg
- 3 Star Hotels in Park Hills
- La Quinta Inn & Suites Hotels in Farmington
- Park Hills Hotels
- Business Hotel Hotels in Farmington
- Apartments in Eminence
- Cabin Rentals in Van Buren
- Marble Hill Hotels
- Cheap Hotels in Poplar Bluff
- Hotels near Johnson's Shut-ins State Park
- Cabin Rentals in St Mary

































































































