Southern Illinois Guest Houses

A forested valley with autumn foliage, a rocky cliff, and a sunset.

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Our top choices for Southern Illinois guest houses

Lakefront Suite · Dock, No-Wake Cove & Firepit

Marion

Sam M.

HK$2,671 total

includes taxes & fees

28 Jul - 29 Jul

Grand Center Inn

Grand Center

Leon and Janis

HK$1,656 total

includes taxes & fees

6 Jul - 7 Jul

Cozy, Fun, and One-Of-A-Kind!

Shaw

Sam K.

HK$1,086 total

includes taxes & fees

14 Jul - 15 Jul

Charming Home with Country Views

Grafton

m g.

HK$3,092 total

includes taxes & fees

5 Jul - 6 Jul

In the center of all Historic Main Street has to offer

Grafton

Janelle C.

HK$4,874 total

includes taxes & fees

14 Jul - 15 Jul

The Mediterranean House 1858

Perryville

HK$5,451 total

includes taxes & fees

7 Jul - 8 Jul

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Top Southern Illinois Hotel Reviews

Drury Inn & Suites St. Louis Fairview Heights

8/10 Good

"It was a quick overnighter as we arrived late and left early after a quick breakfast, but it was a clean room with no complaints! The staple Drury breakfast was just what we needed to continue on our road trip."

The Principal Hotel

10/10 Excellent

"This was a terrific hotel! It’s a former Catholic school turned into a cute boutique hotel. Our room was well appointed with a comfortable bed. The staff was friendly & very helpful. The town it was located in, Columbia Illinois, was a beautiful small town that was close to St Louis. It made it easy to get to all of our events. We will stay here again when we return to the St Louis area!"

Comfort Inn Edwardsville - St. Louis

8/10 Good

"While our room was clean and comfortable, A/C worked great, the shower needed some bleach work, door track was black and floor pan of shower was orange in spots. We checked in on a Thursday, kids used pool, Friday someone apparently barged in pool. We were told pool had to be drained, cleaned, refilled. Next 3 days, we never saw any of this being done. VERY DISSAPPOINTING as now the kids couldn't swim, 98° outside!!! A very faint apology with no amends from staff."

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