Photo by Southernmost Illinois Tourism Bureau
Southern Illinois Spa Hotel
Change your mindBook hotels with free cancellation
Be pickySearch almost a million properties worldwide
Check availability on Southern Illinois Spa Hotel
Our top choices for Southern Illinois hotels with a spa
9.4 out of 10, Exceptional, (418 reviews)
"Our room was clean, and very spacious! the establishment was very nice! We had reservations at Ruthie’s and it was amazing like always "
Amy
The price is HK$1,250
HK$1,387 total
includes taxes & fees
23 Feb - 24 Feb
Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG
Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHGCape Girardeau
9.4 out of 10, Exceptional, (1,004 reviews)
"Breakfast was very good and staff was extremely friendly and rooms were very clean "
Rex
The price is HK$711
HK$802 total
includes taxes & fees
8 Mar - 9 Mar
9.2 out of 10, Wonderful, (403 reviews)
"Nice and conveniently located and priced."
Christopher
8.4 out of 10, Very good, (1,001 reviews)
"The room was great. I enjoyed my stay. "
Wanda
The price is HK$1,470
HK$1,848 total
includes taxes & fees
1 Mar - 2 Mar
8.4 out of 10, Very good, (134 reviews)
"The staff were wonderful! We got in late, and they had everything set for us to self check-in. The room was clean and updated. It is in a small town with great Amish food. Very safe and affordable. Would definitely stay again!"
Michelle
The price is HK$906
HK$1,006 total
includes taxes & fees
24 Feb - 25 Feb
9.0 out of 10, Wonderful, (1,616 reviews)
"Everything was great i can’t wait to stay again "
Kimbriel
The price is HK$990
HK$1,196 total
includes taxes & fees
15 Mar - 16 Mar
9.4 out of 10, Exceptional, (1,002 reviews)
"Great service, great staff , room service food really good,, great view of the arch and the river. "
Jose
The price is HK$3,243
HK$3,792 total
includes taxes & fees
23 Feb - 24 Feb
10.0 out of 10, Exceptional, (37 reviews)
"Wonderful stay! This home is beautiful. Our hosts Sandy and Jim were gracious and it was a pleasure to be with them for the evening. Highly recommended!"
Jeff
The price is HK$2,283
HK$2,602 total
includes taxes & fees
2 Mar - 3 Mar
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Top Southern Illinois Hotel Reviews
Drury Plaza Hotel Mt. Vernon
10/10 Excellent
Explore a world of travel with Expedia
- Hotels near Southern Illinois
- Motel 6 Hotels in Carlyle
- Cabin Rentals in Waltonville
- Carlyle Hotels
- Cabin Rentals in Southern Illinois
- 3 Star Hotels in Du Quoin
- Hamilton County Hotels
- Hotels near West Access Marina
- Pet-Friendly Hotel Hotels in Carlyle
- Pet-Friendly Hotel Hotels in Pocahontas
- 5 Star Hotels in Marissa
- Dix Hotels
- Ava Hotels
- Marion Hotels
- Creal Springs Hotels
- 4 Star Hotels in Carbondale
- Cheap Hotels in Grayville
- Family Hotel Hotels in Grayville
- Hotels near Salem Fairgrounds
- Hotels near William Jennings Bryan Statue
- Sparta Hotels
- Farmstay in Southwest Illinois
- Apartments in Carlyle
- Hotel with Pool Hotels in Carlyle
- Pet-Friendly Hotel Hotels in Mount Vernon
- 3 Star Hotels in Aviston
- La Quinta Inn & Suites Hotels in Southern Illinois
- Hotels near William Jennings Bryan Boyhood Home and Museum
- Cheap Hotels in Du Quoin
- 5 Star Hotels in Corinth
- Romantic Hotel Hotels in Carterville
- Lodges in Enfield
- Cabin Rentals in Carbondale
- Noble Hotels
- Nashville Hotels
- Golf Hotel Hotels in Sparta
- 3 Star Hotels in Odin
- 4 Star Hotels in Carmi
- B&B in Southern Illinois
- Guest Houses in Southwest Illinois
- 3 Star Hotels in Carmi
- Ina Hotels
- 4 Star Hotels in Tamaroa
- Spa Hotel Hotels in Carlyle
- Cabin Rentals in Marion
- Casino Hotel Hotels in Southern Illinois
- Sesser Hotels
- Fairfield Hotels
- Drury Inn & Suites Hotels in New Baden
- Hilton Hotels in Ewing
- Motels in Herrin
- 4 Star Hotels in Sims
- Cabin Rentals in Christopher
- Adventure Sport Hotel Hotels in Marion
- Independent Hotels in Centralia
- Hotels near Kokopelli Golf Club
- Cisne Hotels
- Wyndham Hotels in New Baden
- Family Hotel Hotels in Harrisburg
- Red Roof Inn Hotels in Carbondale
- Lodges in Whittington
- Marissa Hotels
- Hotels near Mount Vernon Outland
- Motels in Albion
- Luxury Hotel Hotels in Southern Illinois
- Red Lion Hotels in Southwest Illinois
- Independent Hotels in Sparta
- Cabin Rentals in Dix
- Pet-Friendly Hotel Hotels in Marion
- Extended Stay America Hotels in Carlyle
- Albion Hotels
- 3 Star Hotels in Keyesport
- Mount Vernon Hotels
- Cheap Hotels in Carbondale
- Hotels near Flora City Hall
- Chalets in Southern Illinois
- Apartments in Pinckneyville
- Lodges in Herrin
- Bar Hotel Hotels in Altamont
- Kinmundy Hotels
- Hotels near Rend Lake College