A modern building with a unique triangular roof and a central spire.

Santa Lucia hotels in Syracuse

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Check prices for these dates

This weekend
17 Jul - 19 Jul
Next weekend
24 Jul - 26 Jul

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Our top choices for Santa Lucia hotels

Rooftop terrace

1. Caportigia Boutique Hotel

Caportigia Boutique Hotel
5.0 star property
Santa Lucia
9.4 out of 10, Exceptional, (288 reviews)
"Beautiful hotel with good amenities"
Canada
Alessia
The price is HK$1,427
HK$1,660 total
includes taxes & fees
19 Jul - 20 Jul
Caportigia Boutique Hotel
Front of property

2. Grande Albergo Alfeo

Grande Albergo Alfeo
4.0 star property
Santa Lucia
8.6 out of 10, Excellent, (684 reviews)
"This accommodation was very comfortable and I would highly recommend it."
Australia
Janet
The price is HK$1,101
HK$1,255 total
includes taxes & fees
23 Jul - 24 Jul
Grande Albergo Alfeo
Breakfast area

3. Giuggiulena Villa

Giuggiulena Villa
3.0 star property
Santa Lucia
10.0 out of 10, Exceptional, (130 reviews)
"Amazing stay. Beautiful views and everyone was very friendly. "
United States
Anna
The price is HK$1,936
HK$2,220 total
includes taxes & fees
21 Jul - 22 Jul
Giuggiulena Villa
Porch

4. Piccolo Hotel Casa Mia

Piccolo Hotel Casa Mia
3.0 star property
Santa Lucia
8.6 out of 10, Excellent, (386 reviews)
"This was my favorite stay in Sicily! I love the elevator and the staff were really nice and accommodating. I also want to point out the excellent AC inside the room. I would only suggest a bottle of water inside the room and a personal tea/ coffee station."
United States
Diane
The price is HK$653
HK$745 total
includes taxes & fees
19 Jul - 20 Jul
Piccolo Hotel Casa Mia
Minibar, in-room safe, desk, soundproofing

5. Lakkios

Lakkios
3.0 star property
Santa Lucia
9.2 out of 10, Wonderful, (74 reviews)
"The room appeared to be recently remodeled and was very modern. Of the 4 hotels that we stayed at on this trip, the bed/pillows were the most comfortable. Great view of the marina from our room balcony and public parking (free) was relatively easy. "
United States
Michael
The price is HK$930
HK$1,060 total
includes taxes & fees
28 Jul - 29 Jul
Lakkios
1 bedroom, down duvets, minibar, in-room safe

6. Re Dionisio Luxury Suites

Re Dionisio Luxury Suites
3.0 star property
Santa Lucia
8.8 out of 10, Excellent, (58 reviews)
"Spacious room, dated but comfortable."
United States
Kenneth
The price is HK$1,794
HK$2,063 total
includes taxes & fees
19 Jul - 20 Jul
Re Dionisio Luxury Suites
Coffee/tea maker, electric kettle

7. Nostos rooms & Apartments

Nostos rooms & Apartments
3.0 star property
Santa Lucia
9.0 out of 10, Wonderful, (282 reviews)
"Room clean, air-conditioning good, beds good, staff nice. Not really sound proof, but everyone is respectful and quiet during the night. Staff isn't always at the reception, but that didn't bother us. Super central, super safe. There's no lifts though."
United Kingdom
Amanda
The price is HK$628
HK$716 total
includes taxes & fees
21 Jul - 22 Jul
Nostos rooms & Apartments
Balcony

8. B&B Nike

B&B Nike
Santa Lucia
9.0 out of 10, Wonderful, (88 reviews)
"Clean, good location. "
United States
Salvatore
The price is HK$685
HK$781 total
includes taxes & fees
16 Aug - 17 Aug
B&B Nike
View from room

9. Calafatari B&B

Calafatari B&B
3.0 star property
Santa Lucia
10.0 out of 10, Exceptional, (13 reviews)
"Clean, very convenient for exploring Ortigia. Nice continental breakfast."
United States
Mary
The price is HK$1,018
HK$1,161 total
includes taxes & fees
20 Jul - 21 Jul
Calafatari B&B
Soundproofing, free WiFi

10. Hotel Palazzo Cavalieri

Hotel Palazzo Cavalieri
4.0 star property
Santa Lucia
9.0 out of 10, Wonderful, (43 reviews)
"Good central location & nice breakfast selection "
Australia
Alan
The price is HK$994
HK$1,133 total
includes taxes & fees
26 Jul - 27 Jul
Hotel Palazzo Cavalieri
Terrace/patio

11. Fortaleza Charme House

Fortaleza Charme House
Santa Lucia
10.0 out of 10, Exceptional, (35 reviews)
"Wonderful stay in the center of it all "
United States
lori
The price is HK$1,450
HK$1,653 total
includes taxes & fees
30 Jul - 31 Jul
Fortaleza Charme House
In-room safe, desk, soundproofing, iron/ironing board

12. B&B IL MORO

B&B IL MORO
Santa Lucia
The price is HK$533
HK$812 total
includes taxes & fees
30 Jul - 31 Jul
B&B IL MORO
Lobby lounge

13. Regina Margherita

Regina Margherita
Santa Lucia
7.8 out of 10, Good, (17 reviews)
"The area is so close to the Ortigia Island where the beautiful cathedral and Doumo are. Lovely walk around the entire island and areas to go in the water If you like. Many dining options and shopping too. Wonderful area!"
United States
Laura
The price is HK$691
HK$787 total
includes taxes & fees
26 Jul - 27 Jul
Regina Margherita
Premium bedding, down duvets, memory-foam beds, in-room safe

14. Eos Sea View Apartment

Eos Sea View Apartment
Santa Lucia
10.0 out of 10, Exceptional, (2 reviews)
"Great location and clean apartment."
United States
Siarhei
The price is HK$1,519
HK$1,732 total
includes taxes & fees
29 Jul - 30 Jul
Eos Sea View Apartment
In-room safe, desk, soundproofing, iron/ironing board

15. Casa Miranda Boutique

Casa Miranda Boutique
Santa Lucia
8.0 out of 10, Very good, (2 reviews)
"Great hotel. Close to everything 15min walk into Ortigia and the excursions dock. The staff are incredibly helpful and thoughtful. Rooms are clean and nice. The balcony had great views of the water and ortigia. Highly recommend to anyone visiting Siracusa! "
United States
Aria
The price is HK$1,908
HK$2,189 total
includes taxes & fees
1 Aug - 2 Aug
Casa Miranda Boutique
Premium bedding, desk, cots/infant beds, rollaway beds

16. B&B Siracusa

B&B Siracusa
Santa Lucia
9.0 out of 10, Wonderful, (60 reviews)
"Good location, very modern clean accommodation."
Canada
Malcolm
The price is HK$621
HK$708 total
includes taxes & fees
19 Jul - 20 Jul
B&B Siracusa
Free daily buffet breakfast

17. San Nicola Rooms Siracusa

San Nicola Rooms Siracusa
Santa Lucia
9.4 out of 10, Exceptional, (9 reviews)
"The breakfast was great! The hosts were super friendly and helpful!"
United States
Lin
The price is HK$805
HK$918 total
includes taxes & fees
19 Jul - 20 Jul
San Nicola Rooms Siracusa
View from room

18. Hotel Mediterraneo

Hotel Mediterraneo
3.0 star property
Santa Lucia
7.8 out of 10, Good, (124 reviews)
"Very friendly and helpful staff."
United States
David
The price is HK$672
HK$766 total
includes taxes & fees
26 Jul - 27 Jul
Hotel Mediterraneo
View from room

19. Gymnasium

Gymnasium
3.0 star property
Santa Lucia
8.8 out of 10, Excellent, (42 reviews)
"Nice kitchen area, centrally located."
United States
Richard
The price is HK$517
HK$589 total
includes taxes & fees
19 Jul - 20 Jul
Gymnasium
Exterior

20. Populus

Populus
1.0 star property
Santa Lucia
7.8 out of 10, Good, (75 reviews)
"Just stay somewhere else, plain and simple."
United States
Thomas
The price is HK$727
HK$828 total
includes taxes & fees
18 Jul - 19 Jul
Populus
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Compare popular hotels in Santa Lucia

Property
Property class
Guest rating
Breakfast included
Pool
Spa
Pet-friendly
WiFi included
View from room
Calafatari B&B
3.0 star property
10.0
Exceptional
13 reviews
View
Breakfast area
Giuggiulena Villa
3.0 star property
10.0
Exceptional
130 reviews
View
Rooftop terrace
Caportigia Boutique Hotel
5.0 star property
9.4
Exceptional
288 reviews
View
Minibar, in-room safe, desk, soundproofing
Lakkios
3.0 star property
9.2
Wonderful
74 reviews
View
Coffee/tea maker, electric kettle
Nostos rooms & Apartments
3.0 star property
9.0
Wonderful
282 reviews
View

Where to stay in Santa Lucia

Find the best Santa Lucia areas for the activities you enjoy most.
A historic waterfront with a stone bridge, illuminated buildings, and a calm water body.

Ortigia

Ortigia is popular for its seaside views, and if you're looking for more to see and do, you might think about a trip to Cathedral of Syracuse or Piazza del Duomo.

Ancient ruins with a large amphitheater surrounded by trees.
Photo by William Keller
Open Photo by William Keller

Neapolis

While visiting Neapolis, you might make a stop by sights like Roman Amphitheatre of Syracuse and Archaeological Park of Neapolis.

A natural rock arch over a body of water with people paddling in kayaks.

Grottasanta

Grottasanta is noteworthy for its historical sites, and you can make a stop at top attractions like Pista Ciclabile Siracusa and Ionian Sea.

An ancient amphitheater with stone ruins and a grassy field.

Tiche

Gardens and restaurants are notable features of Tiche. You might consider stopping by Ionian Sea while you're exploring the neighbourhood.

Acradina

You'll enjoy the churches and seaside views in Acradina. You might want to make time for a stop at Ionian Sea or Capuchin Quarry.

Top Santa Lucia Hotel Reviews

Grand Hotel Des Ètrangers - The Leading Hotels of the World

Grand Hotel Des Ètrangers - The Leading Hotels of the World

10/10 Excellent
"Beautiful hotel, breakfast spread was brilliant and room extremely clean. Staff were all so lovely and attentive. We had a great first afternoon at the pool bar and were very well looked after by a young man who went above and beyond - sorry we did not catch his name."
Ross 4-night trip
Posted 5 hours ago
Grand Hotel Des Ètrangers - The Leading Hotels of the World

Frequently asked questions

What is Santa Lucia like?
Santa Lucia is a neighbourhood that people enjoy for its interesting historical sites. Are you looking for Santa Lucia travel tips? Make sure that you visit Porto Piccolo and Ionian Sea while you're in the neighbourhood.
Where is the best hotel for a stay in Santa Lucia?
Based on our traveller data, Grande Albergo Alfeo is one of the top choices for your stay in Santa Lucia. This hotel offers free breakfast and a restaurant. Other good choices for your stay in the area include Caportigia Boutique Hotel and Fortaleza Charme House.
How many hotels will I find in Santa Lucia?
Expedia has 310 hotels and other accommodation options in Santa Lucia to choose from, making this an ideal home base for exploring the greater Syracuse area.
If I need to cancel my hotel reservation in Santa Lucia, will I receive a refund?
Yes! You'll find that most hotel room reservations are fully refundable as long as you cancel prior to the accommodation's cancellation deadline, which often is within 24-48 hours of your check-in date. If your reservation is non-refundable, you may still be able to cancel and get a refund within a 24-hour period of your booking. Enter your dates, click on "Search", then use the "fully refundable" filter to review the best options available in Santa Lucia.
What are the top things to see and do in Santa Lucia?
Landmarks in Santa Lucia that you won't want to miss include Syracuse Forum Ruins and Santa Lucia Bridge. Porto Piccolo and Ionian Sea are some other stops worth a visit in the neighbourhood. A few places to visit in the area around Santa Lucia include Piazza Santa Lucia, Santa Lucia al Sepolcro Basilica and Madonna delle Lacrime. When you're sightseeing in Syracuse, Papyrus Museum and Museo Archeologico Regionale Paolo Orsi are also worth a stop.

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