Santa Lucia hotels in Syracuse

  • Change your mind

    Book hotels with free cancellation
  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
  • Be picky

    Search almost a million properties worldwide

Check prices for these dates

This weekend
Next weekend

Filter by

Guest rating

Selecting then applying a filter from this group will update the results on a new page

Star rating

Our top choices for Santa Lucia hotels

B&B IL MORO

B&B IL MORO
Santa Lucia
The price is HK$692
HK$994 total
includes taxes & fees
4 Jul - 5 Jul
B&B IL MORO

Melody rooms

Melody rooms
Santa Lucia
The price is HK$396
HK$452 total
includes taxes & fees
9 Jul - 10 Jul
Melody rooms

Nostos rooms & Apartments

Nostos rooms & Apartments
3.0 star property
Santa Lucia
9.0 out of 10, Wonderful, (282 reviews)
"Room clean, air-conditioning good, beds good, staff nice. Not really sound proof, but everyone is respectful and quiet during the night. Staff isn't always at the reception, but that didn't bother us. Super central, super safe. There's no lifts though."
United Kingdom
Amanda
The price is HK$768
HK$876 total
includes taxes & fees
7 Jul - 8 Jul
Nostos rooms & Apartments

Hotel Palazzo Cavalieri

Hotel Palazzo Cavalieri
4.0 star property
Santa Lucia
9.0 out of 10, Wonderful, (42 reviews)
"Good central location & nice breakfast selection "
Australia
Alan
The price is HK$742
HK$846 total
includes taxes & fees
5 Jul - 6 Jul
Hotel Palazzo Cavalieri

B&B Nike

B&B Nike
Santa Lucia
9.0 out of 10, Wonderful, (84 reviews)
"Clean, good location. "
United States
Salvatore
The price is HK$646
HK$736 total
includes taxes & fees
22 Jul - 23 Jul
B&B Nike

Le Camere Luxsury Rooms

Le Camere Luxsury Rooms
Santa Lucia
7.0 out of 10, Good, (2 reviews)
"Très belle chambre, mais forte odeur d’humidité, pas de FENÊTRE quartier type « cour des Miracles «  loin du centre historique, pas de supérette ou de restaurant dans le proche voisinage loin de toute commodité"
France
Philippe
The price is HK$526
HK$804 total
includes taxes & fees
23 Jun - 24 Jun
Le Camere Luxsury Rooms

Caportigia Boutique Hotel

Caportigia Boutique Hotel
5.0 star property
Santa Lucia
9.4 out of 10, Exceptional, (283 reviews)
"Everything was really good at this hotel. The location and cleanliness were great to including the staff. The only thing I would say is that if you did need room service, they charge €10 which seemed punitive."
Canada
Valerie
The price is HK$1,611
HK$1,862 total
includes taxes & fees
23 Jun - 24 Jun
Caportigia Boutique Hotel

Isonzo Suites

Isonzo Suites
Santa Lucia
8.8 out of 10, Excellent, (6 reviews)
"."
Italy
Gianluca
The price is HK$535
HK$876 total
includes taxes & fees
11 Jul - 12 Jul
Isonzo Suites

B&B L'INFIORESCENZA

B&B L'INFIORESCENZA
Santa Lucia
8.0 out of 10, Very good, (2 reviews)
"Camera pulita cuscini scomodi pareti sottilissime si sente nelle stanze intorno qualsiasi piccolissimo rumore, colazione al bar cappuccino ottimo e paste molto grandi e buone, negozi nelle vicinanze no e distanza da Ortigia 15 minuti a piedi circa."
Italy
Loris
The price is HK$356
HK$508 total
includes taxes & fees
23 Jun - 24 Jun
B&B L'INFIORESCENZA

Gymnasium

Gymnasium
3.0 star property
Santa Lucia
8.8 out of 10, Excellent, (42 reviews)
"Nice kitchen area, centrally located."
United States
Richard
The price is HK$552
HK$629 total
includes taxes & fees
24 Jun - 25 Jun
Gymnasium

Hotel Mediterraneo

Hotel Mediterraneo
3.0 star property
Santa Lucia
7.8 out of 10, Good, (124 reviews)
"Very friendly and helpful staff."
United States
David
The price is HK$810
HK$924 total
includes taxes & fees
11 Jul - 12 Jul
Hotel Mediterraneo

Piccolo Hotel Casa Mia

Piccolo Hotel Casa Mia
3.0 star property
Santa Lucia
8.6 out of 10, Excellent, (382 reviews)
"Nice place, few minutes walking to the Ortigia island. Many parking lots around!"
United Kingdom
Eliana
The price is HK$655
HK$746 total
includes taxes & fees
5 Jul - 6 Jul
Piccolo Hotel Casa Mia

Fortaleza Charme House

Fortaleza Charme House
Santa Lucia
10.0 out of 10, Exceptional, (33 reviews)
"Wonderful stay in the center of it all "
United States
lori
The price is HK$1,609
HK$1,834 total
includes taxes & fees
20 Jul - 21 Jul
Fortaleza Charme House

B&B Siracusa

B&B Siracusa
Santa Lucia
9.0 out of 10, Wonderful, (60 reviews)
"Good location, very modern clean accommodation."
Canada
Malcolm
The price is HK$736
HK$838 total
includes taxes & fees
23 Jun - 24 Jun
B&B Siracusa

AmaCasa Siracusa

AmaCasa Siracusa
Santa Lucia
10.0 out of 10, Exceptional, (1 review)
"Siamo stati molto bene, la struttura internamente è abbastanza ammodernata e l'accesso è stato"
Italy
Alessandro
The price is HK$736
HK$838 total
includes taxes & fees
24 Jun - 25 Jun
AmaCasa Siracusa

Eos Elegant Apartment & Suites

Eos Elegant Apartment & Suites
Santa Lucia
The price is HK$694
HK$854 total
includes taxes & fees
28 Jun - 29 Jun
Eos Elegant Apartment & Suites

San Nicola Rooms Siracusa

San Nicola Rooms Siracusa
Santa Lucia
9.4 out of 10, Exceptional, (8 reviews)
"The breakfast was great! The hosts were super friendly and helpful!"
United States
Lin
The price is HK$750
HK$855 total
includes taxes & fees
4 Jul - 5 Jul
San Nicola Rooms Siracusa

Eos Serenity Suites

Eos Serenity Suites
Santa Lucia
The price is HK$883
HK$1,006 total
includes taxes & fees
24 Jun - 25 Jun
Eos Serenity Suites

Grande Albergo Alfeo

Grande Albergo Alfeo
4.0 star property
Santa Lucia
8.6 out of 10, Excellent, (680 reviews)
"This accommodation was very comfortable and I would highly recommend it."
Australia
Janet
The price is HK$1,046
HK$1,192 total
includes taxes & fees
28 Jun - 29 Jun
Grande Albergo Alfeo

Lakkios

Lakkios
3.0 star property
Santa Lucia
9.2 out of 10, Wonderful, (71 reviews)
"The room appeared to be recently remodeled and was very modern. Of the 4 hotels that we stayed at on this trip, the bed/pillows were the most comfortable. Great view of the marina from our room balcony and public parking (free) was relatively easy. "
United States
Michael
The price is HK$932
HK$1,062 total
includes taxes & fees
26 Jun - 27 Jun
Lakkios
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Compare popular hotels in Santa Lucia

Property
Property class
Guest rating
Breakfast included
Pool
Spa
Pet-friendly
WiFi included
View from room
Calafatari B&B
3.0 star property
10.0
Exceptional
13 reviews
View
Breakfast area
Giuggiulena Villa
3.0 star property
10.0
Exceptional
129 reviews
View
Rooftop terrace
Caportigia Boutique Hotel
5.0 star property
9.4
Exceptional
283 reviews
View
Minibar, in-room safe, desk, soundproofing
Lakkios
3.0 star property
9.2
Wonderful
71 reviews
View
Soundproofing, free WiFi
Hotel Palazzo Cavalieri
4.0 star property
9.0
Wonderful
42 reviews
View

Where to stay in Santa Lucia

Find the best Santa Lucia areas for the activities you enjoy most.

Ortigia

Ortigia is popular for its seaside views, and if you're looking for more to see and do, you might think about a trip to Cathedral of Syracuse or Piazza del Duomo.

Neapolis

While visiting Neapolis, you might make a stop by sights like Roman Amphitheatre of Syracuse and Archaeological Park of Neapolis.

Grottasanta

Grottasanta is noteworthy for its historical sites, and you can make a stop at top attractions like Pista Ciclabile Siracusa and Ionian Sea.

Acradina

You'll enjoy the churches and seaside views in Acradina. You might want to make time for a stop at Ionian Sea or Capuchin Quarry.

Tiche

Gardens and restaurants are notable features of Tiche. You might consider stopping by Ionian Sea while you're exploring the neighbourhood.

Top Santa Lucia Hotel Reviews

Frequently asked questions

What is Santa Lucia like?
Santa Lucia is a neighbourhood that people enjoy for its interesting historical sites. Are you looking for Santa Lucia travel tips? Make sure that you visit Porto Piccolo and Ionian Sea while you're in the neighbourhood.
Where is the best hotel for a stay in Santa Lucia?
Based on our traveller data, Grande Albergo Alfeo is one of the top choices for your stay in Santa Lucia. This hotel is a short 9-minute walk from Lungomare di Ortigia, and it offers free breakfast and a restaurant. Other good choices for your stay in the area include Nostos rooms & Apartments and Caportigia Boutique Hotel.
How many hotels will I find in Santa Lucia?
Expedia has 312 hotels and other accommodation options in Santa Lucia to choose from, making this an ideal home base for exploring the greater Syracuse area.
If I need to cancel my hotel reservation in Santa Lucia, will I receive a refund?
Yes! You'll find that most hotel room reservations are fully refundable as long as you cancel prior to the accommodation's cancellation deadline, which often is within 24-48 hours of your check-in date. If your reservation is non-refundable, you may still be able to cancel and get a refund within a 24-hour period of your booking. Enter your dates, click on "Search", then use the "fully refundable" filter to review the best options available in Santa Lucia.
What are the top things to see and do in Santa Lucia?
Landmarks in Santa Lucia that you won't want to miss include Syracuse Forum Ruins and Santa Lucia Bridge. Porto Piccolo and Ionian Sea are some other stops worth a visit in the neighbourhood. A few places to visit in the area around Santa Lucia include Piazza Santa Lucia, Santa Lucia al Sepolcro Basilica and Madonna delle Lacrime. When you're sightseeing in Syracuse, Papyrus Museum and Museo Archeologico Regionale Paolo Orsi are also worth a stop.

Explore a world of travel with Expedia