Adults Only Holidays in The South 2026

Photo by Jennifer Hott-Greenway

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Shoreline Island Resort - Exclusively Adult

14200 Gulf Boulevard Madeira Beach FL

4 hours drive from Walt Disney World® Resort

Stay at this beach aparthotel in Madeira Beach. Enjoy free Wi-Fi, free parking and a beach locale. Our guests praise the helpful staff in their reviews. Popular ...

The Southernmost Inn - Adults Only

525 United Street Key West FL

11 hours drive from Walt Disney World® Resort

Stay at this hotel in Key West. Enjoy free breakfast, 2 outdoor pools and parking (surcharge). Our guests praise the breakfast and the pool in their reviews. ...

Upper Deck Hotel and Bar - Adults Only

120 E Atol St. South Padre Island TX

Stay at this hotel in South Padre Island. Enjoy free Wi-Fi, free parking and 2 bars/lounges. Our guests praise the helpful staff in their reviews. Popular attractions ...

9/10 Wonderful! (231 reviews)

"Everything the exceptionally good, from the front desk, to the bar staff. No one under 21 made it even better, no kids running down the halls or jumping on the beds. Definitely will stay there again on our next trip to SPI."

Reviewed on 7 Aug 2026

See all 654,007 properties in The South

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.