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Southeast Missouri 2 Stars Hotels

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Check availability on Southeast Missouri 2 Star Hotels

Tonight
23 Aug - 24 Aug
Tomorrow
24 Aug - 25 Aug
Next weekend
28 Aug - 30 Aug
In two weeks
4 Sept - 6 Sept

Our top choices for Southeast Missouri 2-star hotels

A dining area with tables and chairs, a kitchen area, and a TV mounted on the wall.
A parking lot with a tree in bloom, a red fire hydrant, and a building in the background.
A hotel room with a large bed, two sofas, a desk with a lamp, a microwave, and a TV.
A gym with cardio equipment, a bench press, and a squat rack.

1. Baymont Inn and Suites by Wyndham Farmington, MO

Baymont Inn and Suites by Wyndham Farmington, MO
Farmington
United States
Kellie
HK$458
HK$498 total
includes taxes & fees
30 Aug - 31 Aug
Baymont Inn and Suites by Wyndham Farmington, MO
A spacious lobby with a fireplace, comfortable seating, a staircase, and a large chandelier.
A living room with a stone fireplace, a television mounted above it, and a large sofa with cushions.
A hotel room with a bed, a desk, a chair, a kitchenette, and a bathroom.
An indoor swimming pool with a clear view of the pool area, including the pool's edge, a set of stairs leading into the pool, and a few lounge chairs and tables around the pool.

2. Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG

Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG
Cape Girardeau
United States
ELAINE
HK$800
HK$902 total
includes taxes & fees
21 Sept - 22 Sept
Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG
A hotel lobby with a reception desk, two red armchairs, a floral centerpiece, a framed cityscape picture, and a dining area in the background.
A hotel room with a living area, kitchenette, and a desk with a computer and chair.
A hotel lobby with a reception desk, two red armchairs, a coffee table, a floral centerpiece, and a dining area with wooden tables and chairs.
A hotel lobby with a seating area, a reception desk, and a dining area.

3. Comfort Inn Festus - St Louis South

Comfort Inn Festus - St Louis South
Festus
United States
Joyce
HK$474
HK$554 total
includes taxes & fees
13 Sept - 14 Sept
Comfort Inn Festus - St Louis South
A modern kitchen with a coffee machine, a sink, and a counter. There are four chairs and a table in the dining area.
A hotel room with two beds, a desk, a chair, a TV mounted on the wall, and a mirror.
A compact kitchen with a dark wooden desk, a black refrigerator, a microwave, and a coffee maker.
A hotel reception area with a modern design, featuring a reception desk, a glass door, and a wall with framed pictures and a large number '6' sign.

4. Motel 6 Poplar Bluff, MO

Motel 6 Poplar Bluff, MO
Poplar Bluff
United States
Kathleen
HK$619
HK$694 total
includes taxes & fees
26 Aug - 27 Aug
Motel 6 Poplar Bluff, MO
A modern hotel room with a large bed, a smaller bed, a desk, and a chair. There is a window with curtains and a painting on the wall.
A spacious lobby with a central atrium, a piano, and a reception desk.
A Days Inn hotel with a brick facade, large windows, and a sign above the entrance.

5. Days Inn and Suites by Wyndham Sikeston

Days Inn and Suites by Wyndham Sikeston
Sikeston
United States
Lori
HK$513
HK$585 total
includes taxes & fees
25 Aug - 26 Aug
Days Inn and Suites by Wyndham Sikeston
A hotel room with two beds, a TV, a desk, and a wardrobe.
A living room with a large flat-screen TV, two beige sofas, a coffee table, and a wooden side table.
A spacious lobby with a reception desk, a chandelier, and a large window.
A reception desk with a sign reading "The FARMSTEAD," a vending machine with snacks, and a water cooler.

6. The Farmstead Hotel

The Farmstead Hotel
Caruthersville
United States
Mary
HK$627
HK$713 total
includes taxes & fees
31 Aug - 1 Sept
The Farmstead Hotel
A hotel with a modern design, featuring a prominent sign for Candlewood Suites. There are multiple parking spaces visible in front of the building.
A hotel room with a kitchenette, a bed, a desk, and a TV.
An indoor swimming pool with tiled flooring, a seating area with chairs, and a staircase leading to a door.
A hotel patio with a gazebo, outdoor seating, and a view of the road.

7. Candlewood Suites Cape Girardeau by IHG

Candlewood Suites Cape Girardeau by IHG
Cape Girardeau
United States
Samuel
HK$690
HK$821 total
includes taxes & fees
30 Aug - 31 Aug
Candlewood Suites Cape Girardeau by IHG
A hotel room with a blue sofa, an orange ottoman, a desk with a lamp, a television, and a window with curtains.
A Dear Tree Inn building with a covered entrance and a clear sky at dusk.
A hotel room with two beds, a window with curtains, an air conditioning unit, and a lamp on a nightstand.
A modern dining area with wooden tables and chairs, a kitchen area with a tiled backsplash, and framed pictures on the wall.

8. Pear Tree Inn Cape Girardeau West

Pear Tree Inn Cape Girardeau West
Cape Girardeau
United States
Bonnie
HK$564
HK$637 total
includes taxes & fees
30 Aug - 31 Aug
Pear Tree Inn Cape Girardeau West
A Holiday Inn Express building with a covered entrance, stone pillars, and multiple windows.
A hotel reception area with a reception desk, a large wall clock, and a potted plant.
A hotel room with two beds, a desk with a chair, a TV, and a window with curtains.
A buffet with labeled food items and a patterned wall in the background.

9. Holiday Inn Express & Suites Sikeston Southwest by IHG

Holiday Inn Express & Suites Sikeston Southwest by IHG
Sikeston
United States
michael
HK$768
HK$870 total
includes taxes & fees
20 Sept - 21 Sept
Holiday Inn Express & Suites Sikeston Southwest by IHG
A hotel lobby with a central bar area, multiple dining tables and chairs, large windows, and a patterned carpet.
A reception area with a wooden reception desk, a large painting on the wall, and a potted plant.
A hotel with a covered entrance, a sign indicating a restaurant, and a well-lit parking area.
An indoor swimming pool with clear water, surrounded by lounge chairs and tables, and large windows providing natural light.

10. Best Western Plus Sikeston I-55

Best Western Plus Sikeston I-55
Sikeston
United States
Kevin
HK$700
HK$797 total
includes taxes & fees
30 Aug - 31 Aug
Best Western Plus Sikeston I-55
A Hampton Inn with a stone facade, outdoor seating area, and a fire pit.
A conference room with a large rectangular table, six chairs with patterned upholstery, two modern ceiling lights, a bowl of fruit on the table, and large windows with curtains.
An indoor swimming pool with lounge chairs, a lifeguard stand, and large windows offering a view of the outside.
A Hampton Inn hotel with a modern facade, a stone entrance, and a well-lit entrance area.

11. Hampton Inn Sikeston

Hampton Inn Sikeston
Sikeston
United States
Jeffrey
HK$782
HK$885 total
includes taxes & fees
30 Aug - 31 Aug
Hampton Inn Sikeston
A spacious dining area with multiple tables and chairs, a flat-screen TV mounted on the wall, and large windows providing natural light.

12. Hampton Inn Poplar Bluff

Hampton Inn Poplar Bluff
Poplar Bluff
United States
Philip
HK$733
HK$821 total
includes taxes & fees
13 Sept - 14 Sept
Hampton Inn Poplar Bluff
A modern kitchen with a central island, built-in appliances, and a view into the dining area.
A swimming pool area with a clear pool, a lifeguard chair, and a sign indicating the pool's depth.
A hotel room with a bed, a desk, a microwave, a coffee maker, and a TV mounted on the wall.
A modern hotel with a stone facade, multiple windows, outdoor seating, and a visible sign for the Holiday Inn Express & Suites.

13. Holiday Inn Express Hotel & Suites FESTUS - SOUTH ST. LOUIS by IHG

Holiday Inn Express Hotel & Suites FESTUS - SOUTH ST. LOUIS by IHG
Festus
United States
Justen
HK$808
HK$923 total
includes taxes & fees
20 Sept - 21 Sept
Holiday Inn Express Hotel & Suites FESTUS - SOUTH ST. LOUIS by IHG
A modern hotel lobby with a reception desk, a bar area, a seating area, and a patterned carpet.
A Holiday Inn Express & Suites building with a covered entrance and stone pillars.
A hotel lobby with a patterned carpet, seating area, and a reception desk.
A swimming pool with clear blue water, surrounded by lounge chairs and tables, with pool rules signs on the wall.

14. Holiday Inn Express & Suites Perryville by IHG

Holiday Inn Express & Suites Perryville by IHG
Perryville
United States
Brandy
HK$760
HK$871 total
includes taxes & fees
6 Sept - 7 Sept
Holiday Inn Express & Suites Perryville by IHG

15. Crown Pointe Lodge, BW Signature Collection

Crown Pointe Lodge, BW Signature Collection
Farmington
United States
Louise
HK$800
HK$870 total
includes taxes & fees
30 Aug - 31 Aug
Crown Pointe Lodge, BW Signature Collection
A modern retail area with a display of local items and snacks.
An outdoor patio area with seating arrangements, including a sofa and chairs, and a table.
A hotel room with two beds, a desk, a chair, a TV, and a window with a view.
A modern indoor seating area with blue sofas and tables, a patterned carpet, and large windows offering a view of the outdoors.

16. Tru By Hilton Cape Girardeau

Tru By Hilton Cape Girardeau
Cape Girardeau
United States
Gwendolyn
HK$701
HK$798 total
includes taxes & fees
30 Aug - 31 Aug
Tru By Hilton Cape Girardeau
A hotel room with a large bathtub, a sofa, a small table, a TV, and a window with curtains.
A hotel room with a kitchenette, a large mirror, a sofa, and a patterned carpet.
A hotel room with a large bed, a desk with a chair, a television, and a small table with a lamp.
A spacious lobby with a checkered floor, two sofas with patterned cushions, a computer desk, and a reception area with a glass door.

17. Super 8 by Wyndham Perryville

Super 8 by Wyndham Perryville
Perryville
United States
Elizabeth
HK$506
HK$580 total
includes taxes & fees
15 Sept - 16 Sept
Super 8 by Wyndham Perryville
A spacious living area with a high ceiling, a green accent wall, and a wooden balcony railing.
A restaurant with multiple tables and chairs, an exit sign, a television, and a counter with food items.
A hotel room with a flat-screen TV, a microwave, a sofa, a lamp, and a window with curtains.
A hotel room with a large bathtub, a bed with a wooden headboard, a nightstand with a lamp, and a painting of a building on the wall.

18. Quality Inn Cape Girardeau North

Quality Inn Cape Girardeau North
Cape Girardeau
United States
Stephen
HK$484
HK$546 total
includes taxes & fees
6 Sept - 7 Sept
Quality Inn Cape Girardeau North
A hotel room with two beds, a desk, a chair, a TV, and a window with curtains.
A reception area with a wooden counter, a desk, and a computer.
A breakfast area with a coffee machine, two coffee dispensers labeled 'Farm Brothers', and cereal boxes including 'Raisin Bran' and 'Frosted Flakes'.
A laundry area with two washing machines and a dryer.

19. Super 8 by Wyndham Potosi

Super 8 by Wyndham Potosi
Potosi
United States
Ross
HK$456
HK$499 total
includes taxes & fees
27 Aug - 28 Aug
Super 8 by Wyndham Potosi
A modern hotel lobby with a bar area, seating, and artwork on the walls.
A modern kitchen with a large island, bar stools, wine bottles, and a built-in TV.
A modern hotel with a prominent sign, a covered entrance, and a well-lit exterior.
A swimming pool with clear blue water, surrounded by sun loungers and a lifeguard stand.

20. Hampton Inn By Hilton Dexter

Hampton Inn By Hilton Dexter
Dexter
United States
Joyce
HK$765
HK$859 total
includes taxes & fees
29 Aug - 30 Aug
Hampton Inn By Hilton Dexter
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Explore similar 3-star hotels

Many 3-star hotels have the same amenities as 2-star hotels. See all 3-star hotels in Southeast Missouri.
Drury Plaza Hotel Cape Girardeau Conference Center

Drury Plaza Hotel Cape Girardeau Conference Center

3351 Percy Drive Cape Girardeau MO
HK$784
HK$884 total
30 Aug - 31 Aug
includes taxes & fees
9.6/10 Exceptional! (1,014 reviews)
Drury Plaza Hotel Cape Girardeau Conference Center
Baymont by Wyndham Festus

Baymont by Wyndham Festus

1200 W. Gannon Drive Festus MO
HK$522
HK$597 total
20 Sept - 21 Sept
includes taxes & fees
Baymont by Wyndham Festus
Drury Inn & Suites Sikeston, MO

Drury Inn & Suites Sikeston, MO

2608 East Malone Ave, Miner Sikeston MO
HK$737
HK$847 total
30 Aug - 31 Aug
includes taxes & fees
9.6/10 Exceptional! (1,011 reviews)
Drury Inn & Suites Sikeston, MO
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Learn more about Southeast Missouri

Discover the family-friendly area of Southeast Missouri—wineries, a scenic riverfront and sights from Sam A. Baker State Park to K Bridge Recreation Area.

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A historical marker sign for the Frisco Depot, detailing its construction in 1928, architectural style, and historical significance.
Photo by Bill Dillard

Top Southeast Missouri Hotel Reviews

Days Inn and Suites by Wyndham Sikeston

Days Inn and Suites by Wyndham Sikeston

10/10 Excellent
"We stay here every time we are in Sikesons. Can't beat this hotel. Super clean 'comfortable!' beds, living room area, and bathrooms. Small hot breakfast. All for the best price out there. Don't skip on this hotel! Staff is always polite and helpful. We always love to walk out to the pond"
Cheyenna 1-night trip
Posted 3 days ago
Days Inn and Suites by Wyndham Sikeston
Postcard Cabins St Francois, Outdoor Collection by Marriott Bonvoy

Postcard Cabins St Francois, Outdoor Collection by Marriott Bonvoy

10/10 Excellent
"Clean room"
Maricela 1-night trip
Posted 3 days ago
Postcard Cabins St Francois, Outdoor Collection by Marriott Bonvoy
Motel 6 Poplar Bluff, MO

Motel 6 Poplar Bluff, MO

8/10 Good
"Clean and nice."
Douglass 1-night trip
Posted 6 days ago
Motel 6 Poplar Bluff, MO

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