Buffalo Buffalo Museum of Science Hotels: 2026 Limited-Time Hotel Deals @Expedia

A large mammoth skeleton in a museum with classical architecture.

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Our top choices for Buffalo Museum of Science hotels

A grand staircase with ornate woodwork and a chandelier, leading to a room with a large wooden door and a stained glass window.

A spacious room with a wooden floor, a fireplace, a dining area with a table and chairs, and a large rug.

A room with a red patterned sofa, wooden bookshelves, a chandelier, and a traditional wooden coffee table.

A large, two-story building with a prominent entrance, multiple windows, and a well-maintained garden.

1. InnBuffalo off Elmwood

Elmwood Village, 3 km from Buffalo Museum of Science

Terese

HK$1,285

HK$1,475 total

includes taxes & fees

20 Oct - 21 Oct

A spacious room with a wooden floor, a fireplace, a dining table, and several chairs.

A historic building with a prominent tower and a large entrance.

A traditional living room with a green sofa, a wooden coffee table with books, a blue armchair, and various potted plants.

A grand hallway with a wooden staircase, a chandelier, and a patterned floor.

2. Buffalo Harmony House

Allentown, 3.2 km from Buffalo Museum of Science

Dustin

HK$2,555

HK$2,971 total

includes taxes & fees

30 Sept - 1 Oct

A spacious dining area with a long table, multiple chairs, a chandelier, and a fireplace.

A bedroom with a four-poster bed, a yellow sofa, a white coffee table, and a desk with a chair.

A living room with a fireplace, two leather armchairs, a coffee table, and a chandelier.

A spacious room with a large wooden table, several chairs, a sofa, and two chandeliers.

3. The Edward Hotel

Elmwood Village, 2.4 km from Buffalo Museum of Science

Barbara

HK$1,169

HK$1,609 total

includes taxes & fees

28 Sept - 29 Sept

A two-story building with a white exterior, a red door, and large windows.

A spacious living area with a granite island, wooden chairs, a fireplace, and a television.

A hot tub with a wooden fence and a brick building in the background.

A living room with a fireplace, leather sofa, and a television mounted on the wall.

4. Buffalo Guesthouse

Allentown, 2.4 km from Buffalo Museum of Science

Jan

HK$1,365

HK$1,566 total

includes taxes & fees

30 Sept - 1 Oct

A hotel room with a bed, desk, chair, TV, and a bathroom with a sink and mirror.

A modern kitchen with a central island, bar stools, and various appliances.

A hotel lobby with a curved reception desk, a chandelier, a seating area with leather chairs, and a tiled floor.

A modern hotel lobby with a round coffee table, two grey armchairs, a TV, and a reception desk.

5. Best Western on the Avenue

Allentown, 2.8 km from Buffalo Museum of Science

John

HK$1,193

HK$1,393 total

includes taxes & fees

18 Oct - 19 Oct

A dining area with a wooden table and chairs, a fireplace, and large windows with a view of greenery outside.

A casino interior with slot machines, a large illuminated pillar, and comfortable seating areas.

A traditional living room with a wooden floor, a sofa, a coffee table, and a fireplace.

A grand staircase with a decorative railing and a Christmas tree adorned with ornaments and ribbons.

6. Summer Street Guest House

Bryant, 3 km from Buffalo Museum of Science

Anthony

HK$2,729

HK$4,032 total

includes taxes & fees

11 Oct - 12 Oct

A dining area with a wooden table set for four, surrounded by chairs. There is a kitchen area with cabinets and appliances in the background.

A modern living room with a sectional sofa, a dining area, and a kitchen in the background.

A kitchen with wooden cabinets, stainless steel appliances, and a red toaster.

A bedroom with a bed, bedside lamps, a nightstand, a window with curtains, and wall art.

7. 4 Mi to Dtwn: Family Home in Buffalo

Masten Park, 1.4 km from Buffalo Museum of Science

HK$2,330

HK$4,127 total

includes taxes & fees

28 Sept - 29 Sept

A buffet setup with various food items and utensils.

A hotel reception desk with a large mirror, a chandelier, and a 'HOTEL' sign.

A hotel room with a large bed, a desk with a chair, a bathroom with a bathtub, and a mirror.

A hotel room with a sofa, a bed, a desk, and a chair. There are lamps on the desk and bedside tables.

8. Salvatores Grand Hotel

13.1 km from Buffalo Museum of Science

Carol

HK$1,326

HK$1,508 total

includes taxes & fees

30 Sept - 1 Oct

A hotel with a prominent entrance, a clock tower, and the name "REIKART HOUSE" displayed above the entrance.

An outdoor patio area with tables and chairs, string lights, and greenery.

A spacious dining area with high ceilings, large windows, and modern chandeliers.

A spacious living area with a fireplace, a large sofa, and a dining area with a table and chairs.

9. Reikart House, Buffalo, a Tribute Portfolio Hotel

8.3 km from Buffalo Museum of Science

Kenneth

HK$2,322

HK$2,641 total

includes taxes & fees

18 Oct - 19 Oct

A modern hotel room with a bed, a desk with a chair, a flat-screen TV, a microwave, and a large mirror.

10. Hampton Inn Buffalo - Amherst, NY

10.6 km from Buffalo Museum of Science

Warren

HK$928

HK$1,056 total

includes taxes & fees

12 Oct - 13 Oct

A modern lounge area with sofas, round tables, and a stone accent wall.

A hotel with a brick facade, multiple balconies, and a sign for 'The Mosey Hotel & Residences'.

11. The Mosey Buffalo Williamsville, Tapestry Collection by Hilton

9 km from Buffalo Museum of Science

Randy

HK$1,727

HK$1,964 total

includes taxes & fees

18 Oct - 19 Oct

A spacious lobby with high ceilings, a grand staircase, and a gift shop.

A bar area with leather barstools, a bar counter, and a television screen.

A bar area with red upholstered bar stools, a bar counter, and a chandelier.

A hotel room with two beds, a desk, a chair, a coffee machine, and a large window with curtains.

12. The Delavan Hotel & Spa

12.4 km from Buffalo Museum of Science

Peter

HK$850

HK$966 total

includes taxes & fees

8 Oct - 9 Oct

A large indoor swimming pool with clear blue water, surrounded by lounge chairs and a sauna area.

A modern hotel room with a large bed, a desk, a TV, and a view of the outdoors.

A multi-story hotel with a prominent entrance, large windows, and a well-lit facade.

A modern lounge area with blue upholstered chairs, a wooden rocking chair, a round table, and a patterned rug.

13. Hampton Inn Buffalo-Williamsville

9.6 km from Buffalo Museum of Science

Robert

HK$1,327

HK$1,510 total

includes taxes & fees

12 Oct - 13 Oct

A patio area with outdoor seating, a barbecue grill, and a stone wall.

A modern lounge area with seating, tables, and hanging chairs.

A modern hotel lobby with a central seating area, a reception desk, and a colorful mural.

14. Tru by Hilton Williamsville Buffalo Airport

13 km from Buffalo Museum of Science

Lachelle

HK$1,060

HK$1,206 total

includes taxes & fees

18 Oct - 19 Oct

A modern kitchen with a central island, wooden cabinets, and a bar area with stools.

An outdoor patio with a round table, chairs, a cushioned seating area, and a barbecue grill.

A modern hotel lobby with a curved seating area, a flat-screen TV, and a dining area.

A modern hotel with a flat roof, large windows, and a covered entrance.

15. Springhill Suites Buffalo Airport

13 km from Buffalo Museum of Science

Matthias

HK$1,052

HK$1,196 total

includes taxes & fees

18 Oct - 19 Oct

A breakfast buffet with various food items and beverages, a large window with a view of buildings, and a patterned floor.

A circular fire pit with a metal railing, surrounded by a stone base, set on a tiled patio with a city skyline in the background.

A heated outdoor swimming pool with lounge chairs and a bar area, surrounded by brick walls and a balcony with decorative lighting.

16. Curtiss Hotel, an Ascend Collection Hotel

Buffalo Theater District, 3.4 km from Buffalo Museum of Science

carrie

HK$2,111

HK$2,464 total

includes taxes & fees

18 Oct - 19 Oct

A spacious lobby with a central seating area, a shop in the background, and potted plants along the walkway.

An outdoor patio with a fire pit, seating, and string lights.

A Hilton Garden Inn hotel with a well-lit entrance, outdoor seating area, and landscaped garden.

A large indoor swimming pool with clear blue water, surrounded by white pillars and blue-tiled edges.

17. Hilton Garden Inn Buffalo Airport

9.4 km from Buffalo Museum of Science

Jessica

HK$1,280

HK$1,494 total

includes taxes & fees

18 Oct - 19 Oct

A hotel reception area with a reception desk, a 'Hilton Honors' sign, a 'HOME 2' sign, a 'really cold' and 'cold' sign above a refrigerator, and a shelf with snacks.

An indoor swimming pool with tiled flooring, seating areas, and potted plants.

A modern indoor seating area with tables and chairs, a sofa with cushions, and hanging pendant lights.

18. Home2 Suites by Hilton Buffalo Airport / Galleria Mall

6.3 km from Buffalo Museum of Science

Tammy

HK$1,363

HK$1,591 total

includes taxes & fees

11 Oct - 12 Oct

A parking lot with cars and a covered walkway.

An indoor swimming pool with clear glass ceilings, tiled floors, and multiple windows offering views of the outdoors.

A hotel room with a bed, a desk, a sofa, and a painting on the wall.

19. Hyatt Place Buffalo/Amherst

8.3 km from Buffalo Museum of Science

Samuel

HK$1,263

HK$1,437 total

includes taxes & fees

11 Oct - 12 Oct

An outdoor patio with wicker furniture and a large glass window.

A hotel room with a bed, a sofa, a small table, a TV, and a window with curtains.

A multi-story hotel with a central courtyard, large windows, and a well-lit entrance.

A spacious indoor area with a dining area, seating, a fireplace, and a kitchen in the background.

20. Staybridge Suites West Seneca by IHG

9.4 km from Buffalo Museum of Science

Nancy

HK$2,039

HK$2,320 total

includes taxes & fees

30 Sept - 1 Oct

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Compare popular hotels close to Buffalo Museum of Science

Property	Property class	Guest rating
InnBuffalo off Elmwood	10.0 Exceptional 224 reviews	View
Buffalo Harmony House	10.0 Exceptional 54 reviews	View
The Edward Hotel	9.6 Exceptional 262 reviews	View
Buffalo Guesthouse	9.4 Exceptional 206 reviews	View
Best Western on the Avenue	8.8 Excellent 1,005 reviews	View

Top Buffalo Museum of Science Hotel Reviews

Hyatt Regency Buffalo / Hotel and Conference Center

8/10 Good

"I really like the lobby and the clean hotel room. The staff at the front desk was a little slow with the request though."

M Hotel Buffalo

8/10 Good

"Rooms were fine but a little outdated. Looked like the hotel is under going renovations to address this."

The Edward Hotel

10/10 Excellent

"Beautiful restored mini mansion close to Elmwood Village, art gallery, Delaware Park. Gorgeous curated rooms! I stayed in the Green Suite and I will be staying again next time I’m in Buffalo."

Spacious Historical Home by Parks, Shops, 4bd 2ba Save Weekly & monthly.

10/10 Excellent

"No problems"

Delightful dwelling

10/10 Excellent

"Property was very clean, functional and provided everything we needed. The location was good - short drives to most attractions. We would stay again."

Elmwood Village home

8/10 Good

"We were a family of 6 adults in town for a wedding. This older house provided everything we needed to be comfortable and ready for the weekend. We appreciated the air conditioning, ceiling fans, iron, large kitchen and private parking. The house is in a safe area and near a beautiful part of Elmwood. We didn’t end up needing the second shower (which btw is in an unfinished basement). The main bathroom is large, bright and clean. The kitchen had lots of appliances—everything you might want to cook your meals. My only suggestion is brighter or more lighting for working at the counters. The host, Merhawit, was super helpful when we discovered that my son had left some clothing behind. She responded immediately and arranged to have them ready to be picked up by a friend. Overall, we had a great experience staying at Elmwood house."

Stunning Elmwood Village Lower

10/10 Excellent

"Recently renovated, very clean and comfortable stay. Great location, would be happy to stay again!"

Spacious! Game Room, near Restaurants, Bars, Shops, DT BFLO & Niagara Falls!

10/10 Excellent

"Great location, fun place to stay with a very nice owner."

Nice and cozy house with king bed fenced yard

8/10 Good

"Was only there for over night stay. Comfortable"

Other attractions near Buffalo Museum of Science

Buffalo Central Terminal

You can find out about the history of Buffalo with a stop at Buffalo Central Terminal. Experience the entertainment choices and great live music in this vibrant area.

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Johnnie B. Wiley Sport Pavilion

Catch an event at Johnnie B. Wiley Sport Pavilion during your trip to Buffalo. Experience the area's entertainment choices and great live music.

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Paul Robeson Theater

Get tickets for a show at Paul Robeson Theater, a theatre with a story to tell in Buffalo. Experience the area's entertainment choices and great live music.

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African American Cultural Center

Enjoy a stop at African American Cultural Center, an entertaining place to visit in Buffalo. Experience the area's acclaimed theatre scene and great live music.

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Broadway Market

You can browse for the perfect souvenirs at Broadway Market during your visit to Buffalo. Experience the area's acclaimed theatre scene and great live music.

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Koessler Athletic Center

Catch an event at Koessler Athletic Center during your trip to Buffalo.

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Montante Cultural Center

Enjoy an outing to Montante Cultural Center during your stay in Buffalo.

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Hellenic Orthodox Church of the Annunciation

After visiting Hellenic Orthodox Church of the Annunciation, make a plan to see the other sights and activities in Buffalo.

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Frequently asked questions

What's the area like around Buffalo Museum of Science?

Buffalo Museum of Science is located in a historic area of Buffalo known for its great live music scene. If you're looking for a convenient place to stay, take a look at the 13 hotels and other accommodation options you'll find within a mile.

What's the best place to stay near Buffalo Museum of Science?

Wyndham Garden Buffalo Downtown is one of the top choices for your stay based on our traveller data, and this hotel offers free breakfast and a 24-hour fitness centre. It's located 1.2 mi (1.9 km) from Buffalo Museum of Science. Other good choices within 5 miles include Buffalo Guesthouse and Hyatt Regency Buffalo / Hotel and Conference Center.

How many hotels will I find close to Buffalo Museum of Science?

Expedia has 13 hotels and other accommodation options within a mile from Buffalo Museum of Science.

If I need to cancel the hotel reservation for my stay near Buffalo Museum of Science, will I receive a refund?

Yes, most hotel room reservations are refundable provided that you cancel prior to the hotel's cancellation deadline, which in most cases is within 24 or 48 hours of the scheduled arrival. If your reservation is non-refundable, you might be able to still cancel and be given a refund within a 24-hour period of your booking. Plug in your dates, click on "Search", then you can filter by "fully refundable" to view the best deals near Buffalo Museum of Science.

What can I see and do near Buffalo Museum of Science?

Study the collections at Buffalo AKG Art Museum, Buffalo History Museum or Buffalo and Erie County Naval and Military Park. Some landmarks that you won't want to miss include Buffalo Central Terminal, Statler Tower and Peace Bridge. You can watch performances at Kleinhans Music Hall, Town Ballroom and Helium Comedy Club - Buffalo if you're interested in local theatre.

Buffalo Buffalo Museum of Science Hotels

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Treat yourself

Be picky

Check prices for these dates

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Our top choices for Buffalo Museum of Science hotels

1. InnBuffalo off Elmwood

2. Buffalo Harmony House

3. The Edward Hotel

4. Buffalo Guesthouse

5. Best Western on the Avenue

6. Summer Street Guest House

7. 4 Mi to Dtwn: Family Home in Buffalo

8. Salvatores Grand Hotel

9. Reikart House, Buffalo, a Tribute Portfolio Hotel

10. Hampton Inn Buffalo - Amherst, NY

11. The Mosey Buffalo Williamsville, Tapestry Collection by Hilton

12. The Delavan Hotel & Spa

13. Hampton Inn Buffalo-Williamsville

14. Tru by Hilton Williamsville Buffalo Airport

15. Springhill Suites Buffalo Airport

16. Curtiss Hotel, an Ascend Collection Hotel

17. Hilton Garden Inn Buffalo Airport

18. Home2 Suites by Hilton Buffalo Airport / Galleria Mall

19. Hyatt Place Buffalo/Amherst

20. Staybridge Suites West Seneca by IHG

Compare popular hotels close to Buffalo Museum of Science

Top Buffalo Museum of Science Hotel Reviews

Hyatt Regency Buffalo / Hotel and Conference Center

M Hotel Buffalo

The Edward Hotel

Spacious Historical Home by Parks, Shops, 4bd 2ba Save Weekly & monthly.

Delightful dwelling

Elmwood Village home

Stunning Elmwood Village Lower

Spacious! Game Room, near Restaurants, Bars, Shops, DT BFLO & Niagara Falls!

Nice and cozy house with king bed fenced yard

Other attractions near Buffalo Museum of Science

Buffalo Central Terminal

Johnnie B. Wiley Sport Pavilion

Paul Robeson Theater

African American Cultural Center

Broadway Market

Koessler Athletic Center

Montante Cultural Center

Hellenic Orthodox Church of the Annunciation

Frequently asked questions