Defiance hotels from HK$613
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25 Aug - 26 AugTomorrow
26 Aug - 27 AugThis weekend
28 Aug - 30 AugNext weekend
4 Sept - 6 SeptOur top choices for Defiance hotels
1. Holiday Inn Express St. Louis West - O'Fallon by IHG
Holiday Inn Express St. Louis West - O'Fallon by IHGO'Fallon
David
HK$791
HK$934 total
includes taxes & fees
30 Aug - 31 Aug
2. TownePlace Suites by Marriott St. Louis Chesterfield
TownePlace Suites by Marriott St. Louis ChesterfieldChesterfield
Bobbi jo
HK$1,003
HK$1,177 total
includes taxes & fees
4 Sept - 5 Sept
3. Sleep Inn & Suites O'Fallon MO - Technology Drive
Sleep Inn & Suites O'Fallon MO - Technology DriveO'Fallon
Josh
HK$616
HK$727 total
includes taxes & fees
15 Sept - 16 Sept
4. The Wildwood Hotel
The Wildwood HotelWildwood
Hailey
HK$691
HK$806 total
includes taxes & fees
1 Sept - 2 Sept
5. Comfort Inn & Suites Chesterfield - St. Louis
Comfort Inn & Suites Chesterfield - St. LouisChesterfield
Joe
HK$706
HK$849 total
includes taxes & fees
30 Aug - 31 Aug
6. Drury Plaza Hotel St. Louis Chesterfield
Drury Plaza Hotel St. Louis ChesterfieldChesterfield
Andrea T
HK$1,019
HK$1,182 total
includes taxes & fees
30 Aug - 31 Aug
7. Hyatt Place St. Louis/Chesterfield
Hyatt Place St. Louis/ChesterfieldChesterfield
Taylor
HK$916
HK$1,063 total
includes taxes & fees
13 Sept - 14 Sept
8. Courtyard by Marriott St. Louis Chesterfield
Courtyard by Marriott St. Louis ChesterfieldChesterfield
Kelly
HK$980
HK$1,141 total
includes taxes & fees
30 Aug - 31 Aug
9. Hampton Inn & Suites St. Louis/Chesterfield
Hampton Inn & Suites St. Louis/ChesterfieldChesterfield
Karen E
HK$861
HK$1,002 total
includes taxes & fees
13 Sept - 14 Sept
10. Staybridge Suites O'Fallon Chesterfield by IHG
Staybridge Suites O'Fallon Chesterfield by IHGO'Fallon
Norman
HK$870
HK$1,026 total
includes taxes & fees
31 Aug - 1 Sept
11. Holiday Inn Express & Suites St. Louis - Chesterfield by IHG
Holiday Inn Express & Suites St. Louis - Chesterfield by IHGChesterfield
NEBAHAT
HK$893
HK$1,040 total
includes taxes & fees
30 Aug - 31 Aug
12. Residence Inn by Marriott O'Fallon
Residence Inn by Marriott O'FallonO'Fallon
Gerald
HK$1,027
HK$1,211 total
includes taxes & fees
13 Sept - 14 Sept
13. Drury Inn & Suites St. Louis St. Peters
Drury Inn & Suites St. Louis St. PetersSt. Peters
Melanie
HK$862
HK$991 total
includes taxes & fees
30 Aug - 31 Aug
14. Best Western Plus Washington Hotel
Best Western Plus Washington HotelWashington
Michael Macumber
HK$1,011
HK$1,151 total
includes taxes & fees
30 Aug - 31 Aug
15. Hilton Garden Inn St. Louis/O'Fallon MO
Hilton Garden Inn St. Louis/O'Fallon MOO'Fallon
Kassie
HK$957
HK$1,135 total
includes taxes & fees
31 Aug - 1 Sept
16. Comfort Inn Near Six Flags St. Louis
Comfort Inn Near Six Flags St. LouisPacific
David
HK$733
HK$839 total
includes taxes & fees
20 Sept - 21 Sept
17. Sonesta ES Suites St. Louis - Chesterfield
Sonesta ES Suites St. Louis - ChesterfieldChesterfield
Ernest L
HK$779
HK$904 total
includes taxes & fees
26 Aug - 27 Aug
18. Fairfield Inn & Suites by Marriott St. Louis Chesterfield
Fairfield Inn & Suites by Marriott St. Louis ChesterfieldChesterfield
Carl
HK$933
HK$1,082 total
includes taxes & fees
30 Aug - 31 Aug
19. Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham
Heritage Inn & Suites St. Louis/Fenton, Trademark by WyndhamFenton
LINDSAY
HK$739
HK$854 total
includes taxes & fees
26 Aug - 27 Aug
20. Quality Inn Near Six Flags St. Louis
Quality Inn Near Six Flags St. LouisPacific
Diane
HK$737
HK$844 total
includes taxes & fees
20 Sept - 21 Sept
Stay near popular Defiance attractions
August A. Busch Memorial Conservation Area
8.6/10 (7 reviews)
This sprawling conservation area features over 30 lakes and historic WWII bunkers amid diverse habitats. Explore well-maintained trails while watching for migratory birds and wildlife in their natural environment.
Photo by Pages of Travel
Chandler Hill Vineyards
7.8/10 (7 reviews)
This elegant Missouri winery showcases local and California wines from its hillside setting. Savour varietals on the expansive terrace while enjoying vineyard views and seasonal cuisine from their full-service kitchen.
Historic Daniel Boone Home and Heritage Center
9.6/10 (4 reviews)
Step into the limestone home where Daniel Boone's son Nathan crafted a frontier masterpiece with seven fireplaces. Explore the surrounding historic village for an authentic glimpse into 19th-century pioneer life.
Sugar Creek Winery
8.0/10 (1 review)
Sip award-winning Missouri wines at this hillside vineyard along the scenic Katy Trail. Relax on covered decks with your own picnic while enjoying live weekend music and panoramic countryside views.
Yellow Farmhouse Winery
This boutique winery in Defiance, Missouri was known for its distinctive unfiltered wines and relaxed atmosphere. Visitors could enjoy tastings with live music while picnicking on scenic grounds with vineyard views.
Matson Hill Park Trailhead
Wander through 475 acres of rugged forest terrain with challenging hiking paths and gravity-flow mountain bike trails. The historic 1830s Hays Home offers a glimpse into pioneer life amid the natural splendour.
Broemmelsiek Park
This 494-acre natural playground offers nine miles of trails through forests and around serene lakes. Attend a monthly stargazing event at the astronomy viewing area for a uniquely celestial park experience.
Hamburg Trail Trailhead
This moderate 6.9-mile loop winds through the scenic Weldon Spring Conservation Area, connecting to the Katy Trail State Park. Spot native wildlife while traversing diverse landscapes of shaded woodlands and open fields.
Learn more about Defiance
Nestled along the Missouri River, this historic village offers scenic hiking trails and access to nearby wine country. Visit the Daniel Boone Home in neighbouring Defiance Township or enjoy tastings at the family-owned wineries dotting the surrounding countryside.
See all hotels in Defiance
Top Defiance Hotel Reviews
Best Western Plus St. Louis West-Westport
10/10 Excellent
"Front desk staff was helpful"
Sleep Inn & Suites O'Fallon MO - Technology Drive
10/10 Excellent
"Very clean hotel, with a great, convenient location..Staff was polite and helpful, and the morning breakfast was delicious"
Drury Inn & Suites Southwest St. Louis
10/10 Excellent
"10 out of 10 will stay again"
Hollywood Casino & Hotel St. Louis
10/10 Excellent
"Stayed at the property for a concert. The shuttle service from the hotel to the venue was convenient. Casino was large and not very crowded for a Sunday night. Room was clean and functional. We would stay here for another concert/casino overnight."
Sonesta ES Suites St. Louis - Chesterfield
10/10 Excellent
"Nice"
Holiday Inn St. Louis West Six Flags by IHG
8/10 Good
"Our room was not clean when we arrived. There were whiskers in and around the sink, and dead bugs in the shower."
Best Western Plus Fenton
10/10 Excellent
"I found the ice cream machine to be so much a wonderful surprise! Everything was clean and everyone was quite friendly!"
Ameristar Casino Resort and Spa
10/10 Excellent
"Great location and atmosphere! Rooms are so spacious and nice. Will definitely stay again!"
Courtyard by Marriott St Louis Westport Plaza
10/10 Excellent
"Absolutely loved this place. Comfy beds. Spacious suites"
More cheap stays in Defiance
Days Inn and Suites by Wyndham St. Louis/Westport Plaza
1970 Craig Rd Maryland Heights MO
HK$533
HK$618 total
27 Aug - 28 Aug
includes taxes & fees
Sleep Inn & Suites O'Fallon MO - Technology Drive
1147 Technology Drive O'Fallon MO
HK$616
HK$727 total
15 Sept - 16 Sept
includes taxes & fees
9/10 Wonderful! (1,105 reviews)
Best Western Plus St. Louis West-Westport
12220 Dorsett Rd Maryland Heights MO
HK$693
HK$804 total
6 Sept - 7 Sept
includes taxes & fees
8/10 Very good! (1,102 reviews)
Best Western Plus Fenton
1680 Fenton Business Park Ct Fenton MO
HK$744
HK$859 total
30 Aug - 31 Aug
includes taxes & fees
9/10 Wonderful! (439 reviews)
Hampton Inn St. Charles St. Peters
3720 W Clay St St. Charles MO
HK$765
HK$879 total
3 Sept - 4 Sept
includes taxes & fees
Holiday Inn Express & Suites St. Louis - Chesterfield by IHG
11 Arnage Boulevard Chesterfield MO
HK$893
HK$1,040 total
30 Aug - 31 Aug
includes taxes & fees
