Santa Ana Holidays

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Where to stay in Santa Ana

Find the best Santa Ana areas and neighborhoods for the activities you enjoy most. Learn more about Santa Ana
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Casco Viejo

3.5/5(3 area reviews)

Unique features of Casco Viejo include the historical sites and bars. Make a stop by Metropolitan Cathedral of Panama or Interoceanic Canal Museum while you're exploring the area.

Find hotels in Casco Viejo

Top hotels in Santa Ana

Casco View Apartments
Casco View Apartments
3 out of 5
C. 16 Oeste, Panama City, Provincia de Panamá
9.4/10 Exceptional! (38 reviews)
"I liked the buildings quietness and modern style."

Reviewed on 23 Jun 2025

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Casco View Apartments
Hotel Riu Plaza Panama
Hotel Riu Plaza Panama
5 out of 5
Calle 50, Urb. Marbella, Panama City, Panama
Fully refundableReserve now, pay when you stay
The price is HK$934 per night from 13 Jul to 14 Jul
HK$934
HK$1,028 total
13 Jul - 14 Jul
includes taxes & fees
9/10 Wonderful! (4,083 reviews)
"THE CENTER OF CITY, CLOSE TO NUMBER OF ACTIVITIES. WEEKDAY VERY CONGESTED ROADS."

Reviewed on 10 Jul 2025

Hotel Riu Plaza Panama
Dreams Playa Bonita Panama - All Inclusive
Dreams Playa Bonita Panama - All Inclusive
4 out of 5
KM 7, Road to Veracruz, Veracruz, Panama
Fully refundableReserve now, pay when you stay
The price is HK$1,923 per night from 1 Aug to 2 Aug
HK$1,923
HK$1,923 total
1 Aug - 2 Aug
includes taxes & fees
7.2/10 Good! (1,001 reviews)
"We had a wonderful stay at Dreams Playa Bonita. The staff is very welcoming and hospitable. The room was clean and with a beautiful beach view. We loved that they had breakfast, lunch, and dinner all included. They also have coffee and snack shops open throughout the day! To us, this has been the ..."

Reviewed on 5 Jul 2025

Dreams Playa Bonita Panama - All Inclusive
See all 1,462 properties in Santa Ana
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Frequently asked questions

How much does a Santa Ana vacation package cost?
From as little as . Yes, you read that correctly. Our Santa Ana vacation packages are an easy way to stretch your budget further. Combine your favorite hotels, flights and rental car and explore this destination your way.
How do I get a cheap travel package to Santa Ana?
One of the easiest ways to save cash (and time) is to combine your bookings with Expedia. Flights, hotels, activities and rental cars --- we've got it all. Pick and choose the combination that best fits you and see your savings grow. We know a package deal is never a one-size-fits-all. That's why Expedia offers over 550 air carriers and 1,000,000 hotels throughout the world, which lets you customize your Santa Ana holiday.
Where should I stay in Santa Ana?
Most who travel to Santa Ana include both Miraflores Locks and Metropolitan Cathedral of Panama on their bucket lists. Why not go for a hotel right near these great attractions?
What are the top hotels in Santa Ana?
If it's your first time in Santa Ana, make a reservation at Hotel Riazor or Hotel Doral. Both hotels will make you feel at home and are favourites among lots of travellers.
How far in advance should I book my Santa Ana holiday?
While prices change from time to time, we generally suggest booking your seats as soon as possible. Most international airfares are available on Expedia up to a year in advance. If circumstances have left you booking late, you might still be in luck. Low prices to Santa Ana sometimes occur only weeks before departure.
What does an Expedia Santa Ana travel package include?
That mostly depends on you. You can select from a range of Santa Ana packages, such as a rental car, flight and hotel. You can also book a hotel and a flight, or a rental car and a flight. Once you've made your booking, you can add on the fun stuff like tours and activities. Whatever your perfect Santa Ana break looks like, get set to save!
What should I know before booking a Santa Ana travel package?
Discover deals to suit your budget with an Expedia package. Hotels, airfares, rental cars --- we've got everything you need to plan your getaway. You'll save big dollars just for bundling your bookings. Whether you're taking off on a ski trip or getting some sun on a warm beach, your ideal getaway is only clicks away.
Can I choose my airline with a Santa Ana Expedia holiday package?
Definitely. Expedia has more than 550 airline partners to pick from globally. With all that choice at your fingertips, finding the right carrier to get you to Santa Ana shouldn't be hard.
If I'm not able to travel, can I cancel my Santa Ana vacation package?
We totally get it --- life can throw you the odd curveball. If you've booked a Santa Ana vacation package and have to amend or cancel it, we're here to help. It's always worth visiting our Customer Service Portal first for information. But generally, if you've booked your package in the last 24 hours, you may be able to amend or cancel your itinerary at no cost. If it's been longer than 24 hours, your hotel, airline or car rental company may charge a fee.

Popular places to visit

Panama Canal Railway

Panama Canal Railway

Enjoy an outing to Panama Canal Railway during your stay in Ancon. Stroll along the seaside or visit the shops in this vibrant area.

Panama Canal Railway

Albrook Shopping Mall

4/5(5 reviews)

You can find the perfect gifts to bring home with a trip to Albrook Shopping Mall, a favourite shopping spot in Ancon. Amble around this culturally rich area's seaside and enjoy its top-notch restaurants.

Albrook Shopping Mall

El Dorado Mall

3/5(1 review)

During your trip to Panama City, you can browse for the perfect souvenirs at El Dorado Mall. Stroll along the seaside in this vibrant area or visit its lively bars.

El Dorado Mall

Things to do

Slingshot Tour Panama

Slingshot Tour Panama

HK$921
per adult
Slingshot Tour Panama
Cinta Costera

Half day of Panama city and canal tour: shared and private

HK$523
per adult
98% of travellers recommend
Half day of Panama city and canal tour: shared and private
Day Tour

Day Tour in San Blas Islands All Included Visiting 4 Islands

HK$1,170
per adult
94% of travellers recommend
Day Tour in San Blas Islands All Included Visiting 4 Islands
See all activities in Panama City
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.