Santa Ana
Panama City
Popular places to visit
Multiplaza Pacific Mall
During your trip to Panama City, you can search for that perfect souvenir at Multiplaza Pacific Mall. You can enjoy the restaurants while in the area.
Avenida Balboa
You can browse for the perfect souvenirs at Avenida Balboa during your stay in Panama City. While you're in the area, wander around the natural setting.
Amador Causeway
You can learn about the history of Ancon with a visit to Amador Causeway. Stroll along the seaside or visit the shops in this vibrant area.
Cinta Costera
Explore the great outdoors at Cinta Costera, a lovely green space in Panama City. While you're in the area, stroll along the seaside.
Calle 50
You can find out about the history of Panama City when you stop by Calle 50. Discover the area's casinos or seek out its local tours.
Uruguay Street
During your visit to Panama City, you can search for that perfect souvenir at Uruguay Street. While in this family-friendly area, you can savour the top-notch restaurants.
Things to do
Panama City: All-Inclusive Catamaran Cruise to Taboga Island
Panama City Visit an Indian town Embera and waterfall with lunch
Panama City: Poin Full Package Experience
The Panama Barcrawl - The OG Crawl (Panama City, Panama)
Visit San Blas Paradise: Day Tour to 4 Islands with Lunch & Drink
All-inclusive 8-hour catamaran tour to Isla Taboga from Panama City
Top hotels in Santa Ana
Casco View Apartments
The room was spotless and the decor was beautiful. The location was very convenient and the staff was friendly, in particular Marciello. The only downsides were that there was no hot water in the shower and the air conditioning vented onto the deck, making it really hot to sit on the deck.
Reviewed on 22 Feb 2026
Hotel Riu Plaza Panama
Had a great stay-great room and food! Unfortunately gift shop was closed for the duration of my stay
Reviewed on 27 Feb 2026
Hotel El Panama by Faranda Grand, a member of Radisson Individuals
Yes greet staff jefeth in front desk, good food, good pool
Reviewed on 25 Feb 2026
Crowne Plaza Panama Airport by IHG
Great breke Clean rooms Very friendly Recommend the hotel highly
Reviewed on 26 Feb 2026
Sheraton Grand Panama
The staff was courteous and overall very helpful. The spaces were clean. They had easy access to taxis if you needed them and the breakfast buffet, and restaurants were delicious. We did ask for extra water a few times and it was stated it would be brought up and never was. Other than that, the stay ...
Reviewed on 23 Feb 2026
W Panama
Most amazing team most amazing staff. Thank you Armando. Thank you team. Thank you everyone of you. You are great to me. We had an amazing time. Everyone should feel welcome. Everyone should want to come to this hotel.
Reviewed on 25 Feb 2026
Other neighbourhoods around Santa Ana
Casco Viejo
Unique features of Casco Viejo include the historical sites and bars. Make a stop by Independence Square or Interoceanic Canal Museum while you're exploring the area.
San Felipe
While visiting San Felipe, you might make a stop by sights like Independence Square and Interoceanic Canal Museum.
El Chorrillo
While El Chorrillo isn't home to many top sights, Maracana Stadium and Flag of Cerro Ancón are some notable places to visit nearby.
Calidonia
Calidonia is a destination travellers like for its shopping, and you might hop aboard the metro at Estación Lotería or Santo Tomas Station to explore sights like Cinta Costera.
Balboa
The restaurants and shopping are just a few features travellers like about Balboa. If you want to do some sightseeing nearby, Albrook Shopping Mall and Bridge of the Americas are a few top places to visit.
Marbella
You'll enjoy the restaurants and parks in Marbella. You might want to make time for a stop at Avenida Balboa or Cinta Costera.
