Gainesville Santa Fe Depot Museum Hotels: 2026 Limited-Time Hotel Deals @Expedia

Change your mind
Book hotels with free cancellation
Treat yourself
Sign in to save 10% or more on thousands of hotels
Sign in
Be picky
Search almost a million properties worldwide

Check prices for these dates

Tonight

Tomorrow

This weekend

Next weekend

Our top choices for Santa Fe Depot Museum hotels

A two-story house with a swimming pool, outdoor furniture, and a well-maintained garden.

A golf course with a pond, a clubhouse, and a parking area.

A wooden deck with a hot tub, outdoor furniture, and a welcome sign on a building.

A beach with a sunset, waves, and a few trees and structures in the distance.

1. The Lancaster Manor B&B

0.8 km from Santa Fe Depot Museum

Jeffrey

HK$1,630

HK$1,875 total

includes taxes & fees

20 Oct - 21 Oct

A conference room with a long table, chairs, a flat-screen TV, and a large mirror on the wall.

A hotel with a modern facade, a covered entrance, and a parking lot.

A modern hotel lobby with a wooden ceiling, a large TV, a sofa, a coffee table, and a patterned floor.

A modern hotel lobby with a wooden ceiling, a reception desk, a seating area with green sofas, and a visible kitchen in the background.

2. Fairfield Inn & Suites by Marriott Gainesville I-35

1.8 km from Santa Fe Depot Museum

BALTAZAR

HK$753

HK$866 total

includes taxes & fees

22 Oct - 23 Oct

A modern hotel room with a large bed, a desk, a chair, and a sofa.

A reception area with a Days Inn sign, a counter with a tiled backsplash, a television, and a coffee machine.

A Days Inn reception area with a stone counter, a dining area with tables and chairs, and a large window on the right side.

A gym with treadmills, elliptical machines, and weight machines.

3. Days Inn by Wyndham Gainesville

2.5 km from Santa Fe Depot Museum

Tina

HK$565

HK$650 total

includes taxes & fees

15 Oct - 16 Oct

A buffet with labeled containers of omelets and other dishes.

A Holiday Inn Express hotel with a covered entrance, multiple windows, and a brick facade.

A coffee station with two coffee machines and a variety of coffee pods and cups.

A hotel room with a bed, a desk, a chair, a sofa, and a ceiling fan.

4. Holiday Inn Express & Suites Gainesville by IHG

1.1 km from Santa Fe Depot Museum

Brent

HK$636

HK$731 total

includes taxes & fees

11 Nov - 12 Nov

A spacious living area with a sofa, a glass-top coffee table, a desk with a computer, and a magazine rack. There is a dining area with tables and chairs in the background.

A hotel hallway with carpeted floors, doors on both sides, and a ceiling with recessed lighting.

A vending machine with various drinks and snacks, a push door, and a digital display.

A hotel room with two beds, a desk, a chair, a TV, and a large window with curtains.

5. Super 8 by Wyndham Gainesville TX

2.7 km from Santa Fe Depot Museum

Sid

HK$541

HK$623 total

includes taxes & fees

18 Oct - 19 Oct

A large indoor swimming pool with clear views through tall windows, a lounge chair, and a table with chairs.

A hotel kitchen with a central island, wooden cabinets, and a breakfast bar.

A room with a blue sofa, a small ottoman, a lamp, and a window with curtains.

A reception desk with a sign reading "Comfort Suites." There are two digital kiosks and a reception counter.

6. Comfort Suites Gainesville

2.5 km from Santa Fe Depot Museum

Tammera

HK$558

HK$642 total

includes taxes & fees

20 Oct - 21 Oct

A kitchen with a countertop, a refrigerator, a ceiling fan, and a window.

A small office with a desk, computer, chair, and a clock on the wall.

A motel with a brick facade, a covered parking area, and a car parked in front.

A bedroom with a bed, a desk, a chair, an air conditioning unit, a door, and a window.

7. Budget Host Motel Gainesville

2.7 km from Santa Fe Depot Museum

Mark

HK$432

HK$496 total

includes taxes & fees

15 Oct - 16 Oct

A hotel room with two beds, a desk with a chair, a television, and a minibar.

A breakfast bar with coffee machines, a refrigerator, and a seating area with a wooden table and chairs.

A modern lobby with a green leather sofa, a glass coffee table, and potted plants.

8. Quality Inn Gainesville

0.9 km from Santa Fe Depot Museum

Roxann

HK$432

HK$502 total

includes taxes & fees

18 Oct - 19 Oct

A spacious living area with a stone accent wall, a brown sofa, and a kitchen in the background.

A gazebo with a roof and open sides, surrounded by grass and trees.

A hotel room with two beds, a desk with a TV, a mirror, and a lamp.

A long corridor with a dining area featuring tables and chairs, a kitchen area, and a reception desk.

9. Loyalty Inn Gainesville

3 km from Santa Fe Depot Museum

Jimmy

HK$367

HK$422 total

includes taxes & fees

22 Oct - 23 Oct

A hotel room with a bed, a desk with a computer, a TV, a microwave, and a refrigerator.

Two refrigerated beverage dispensers labeled 'CHILLED' and 'FROZEN' with various drinks inside.

A spacious dining area with multiple wooden tables and chairs, a counter with food service equipment, and large windows with blinds.

10. Suburban Studios Gainesville

0.9 km from Santa Fe Depot Museum

Lynzee

HK$388

HK$447 total

includes taxes & fees

20 Oct - 21 Oct

A spacious living room with patterned sofas, a coffee table, and a flat-screen TV mounted on the wall.

A modern kitchen with a large island, bar stools, and a flat-screen TV.

A hotel room with two beds, a desk, a TV, and a window.

A Best Western hotel with a brick facade, a covered entrance, and stone pillars.

11. Best Western Red River Inn & Suites

13.9 km from Santa Fe Depot Museum

Douglas

HK$753

HK$844 total

includes taxes & fees

11 Nov - 12 Nov

A spacious kitchen with checkered flooring, wooden cabinets, and various appliances.

A gym with treadmills, elliptical machines, and a weight bench.

A kitchen with wooden cabinets, a refrigerator, and a tiled floor.

A laundry area with a wall-mounted soap, bleach, and softener dispenser, a washing machine, and stacked dryers.

12. Hampton Inn & Suites Gainesville

6.4 km from Santa Fe Depot Museum

Charlie

HK$624

HK$721 total

includes taxes & fees

9 Nov - 10 Nov

A rustic interior with wooden floors, hanging plants, and a rustic ceiling.

An outdoor seating area with wooden chairs and tables, surrounded by trees and string lights.

A backyard with a swimming pool, a wooden pergola, and a stone patio.

A rustic dining area with a stone fireplace, wooden ceiling, and a table set for dining.

13. Oak Meadow Ranch

15 km from Santa Fe Depot Museum

Isaac

HK$1,201

HK$1,768 total

includes taxes & fees

4 Nov - 5 Nov

A spacious lobby with a reception desk, a staircase, and seating area.

A hotel with a red roof, a covered entrance, and a sign for La Quinta Inn & Suites.

A swimming pool with a metal railing, surrounded by lounge chairs and a door in the background.

A hotel room with a large bed, two bedside lamps, a bathroom with a bathtub, and a large mirror.

14. La Quinta Inn & Suites by Wyndham Gainesville

5.7 km from Santa Fe Depot Museum

Teresa

HK$660

HK$775 total

includes taxes & fees

18 Oct - 19 Oct

A hotel room with two beds, each with a green headboard, white bedding, and red accents. There are abstract paintings on the wall above the beds.

A bathroom with a toilet, a shower curtain, a towel rack with towels, and a toilet paper holder.

A building with a sign reading "Lindsay Inn" and a covered entrance area with columns.

A compact kitchen area with a microwave and a black dishwasher.

15. Lindsay Inn

7.9 km from Santa Fe Depot Museum

Tammera

HK$549

HK$615 total

includes taxes & fees

18 Oct - 19 Oct

A hotel room with a bed, bedside table, lamp, and a television on a dresser.

A building with a covered entrance, a clock, and a sign with a flag.

A hotel room with a bed, bedside lamps, a telephone, a nightstand, a window with curtains, and a door.

A spacious lobby with a ceiling fan, a reception desk, a refrigerator, and a door leading to the outside.

16. OYO Hotel Valley View TX, I-35

16.5 km from Santa Fe Depot Museum

Brian

HK$479

HK$565 total

includes taxes & fees

27 Oct - 28 Oct

A modern living room with a fireplace, two bean bag chairs, a television, and large windows with blinds.

A modern restaurant with a bar area, dark wooden flooring, and contemporary furniture.

A living room with a sofa, two bean bags, a coffee table, and a TV mounted on the wall.

A modern hotel lobby with dark wood flooring, comfortable seating, a flat-screen TV, and a reception desk.

17. Red River Inn And Suites

13.9 km from Santa Fe Depot Museum

Troy

HK$777

HK$870 total

includes taxes & fees

18 Oct - 19 Oct

View all properties

Compare popular hotels close to Santa Fe Depot Museum

Property	Property class	Guest rating
The Lancaster Manor B&B	10.0 Exceptional 115 reviews	View
Fairfield Inn & Suites by Marriott Gainesville I-35	8.6 Excellent 1,003 reviews	View
Days Inn by Wyndham Gainesville	7.8 Good 1,000 reviews	View
Holiday Inn Express & Suites Gainesville by IHG	7.8 Good 1,000 reviews	View
Super 8 by Wyndham Gainesville TX	7.2 Good 1,002 reviews	View

Top Santa Fe Depot Museum Hotel Reviews

La Quinta Inn & Suites by Wyndham Gainesville

8/10 Good

"The only thing I did I not like was the bed was kind of hard. Other than that it was nice"

Loyalty Inn Gainesville

10/10 Excellent

"A nice peaceful place to stay. Good price."

Fairfield Inn & Suites by Marriott Gainesville I-35

8/10 Good

"Courtney at the front desk was awesome. Very helpful, friendly and nice. The chair in our room was very wobbly, she found us a replacement right away. The carpet had some spots on it, but the room had a couch and a desk and chair. It was noisy. The bed was clean and comfortable and the shower was great."

Oak Meadow Ranch

10/10 Excellent

"Amazing adventure! Book the Tranquility Cabin and the Serenity Slot experience! We’re still on a high from this experience! It was an absolutely amazing adventure that exceeded every single one of our expectations. The entire process was seamless and incredibly well-organized. The guides/hosts were phenomenally knowledgeable, patient, and full of infectious energy that made the day even more special. It balanced pure excitement with wonderful hospitality, leaving both of us completely captivated. It was genuinely a life-disrupting, beautiful memory that we will treasure forever. Don't even hesitate—just book it! For us, we’re looking forward to arranging to bring more family with us next time for a possible giraffe adventure! Thank you again Oak Meadow Ranch for such a one-a-lifetime adventure!"

Holiday Inn Express Hotel & Suites Gainesville by IHG

10/10 Excellent

"Very clean property….also very convenient location."

Super 8 by Wyndham Gainesville TX

10/10 Excellent

"This is an older property but for the most part is nice, we felt safe. Really like the big fridge it kept our drinks very cold better than most motels. Only thing is all the road construction around the area. If you’re bougie this probably won’t be the place for you."

Budget Host Motel Gainesville

10/10 Excellent

"Every\nThing was excellent, clean room.Good parking , good air conditioner , nice staff"

King Ranch -Stay with Puzzles and Jigsaw the Giraffe

8/10 Good

"we did a monday to friday stay at the king ranch suite, which was an amazing experience. The whole property was also a cool experience with a whole array of animals to interact with. They had a nice outdoor pool which was a 5 minute walk from the room, but not too bad. Staff nice also. No complaints at all, except lack of food/beverages options on the property, you need to basically order uber eats and everything is far away and doesnt taste good. Maybe do some shopping before you come-they have a fridge in the room so you can store essentials to at least have a basic breakfast. Great place to stay for a day, max 2 days; we definitely overdid it with our 5 days and actually left a day early to have a chance to see Dallas before our flight back. Overall I highly recommend them for a short trip you will have a great experience!"

Redbud Falls Ranch | Peaceful Horse Ranch Retreat & Private Horse Experiences

10/10 Excellent

"Melanie is a superb host and the best comminucator out of any VRBO places I've stayed. Her tiny house was an excellent choice. Great escape from traffic, stress, and city life. I would highly recommend."

Other attractions near Santa Fe Depot Museum

Cooke County Courthouse

7.6/10 (89 reviews)

After visiting Cooke County Courthouse, make a plan to see the other sights and activities in Gainesville. While you're in the area, find time to visit its casinos.

See properties

Depot Park

Depot Park is just one of the places to see in Gainesville, so why not enjoy the other things to explore during your travels? While in this family-friendly area, find time to visit its casinos.

See properties

Butterfield Stage Players

7.2/10 (64 reviews)

You can enjoy a show at Butterfield Stage Players during your stay in Gainesville. While you're in the area, find time to visit its casinos.

See properties

State Theater

7.4/10 (54 reviews)

You can enjoy a show at State Theater during your stay in Gainesville. While you're in the area, find time to visit its casinos.

See properties

Morton Museum

7.2/10 (68 reviews)

You can spend time studying the exhibits at Morton Museum during your trip to Gainesville. While you're in the area, find time to visit its casinos.

See properties

Tom Thumb Park

After visiting Tom Thumb Park, make a plan to see the other sights and activities in Gainesville. While in this family-friendly area, find time to visit its casinos.

See properties

Jaycee Park

After visiting Jaycee Park, make a plan to see the other sights and activities in Gainesville. While in this family-friendly area, find time to visit its casinos.

See properties

Gainesville War Memorial

8.0/10 (109 reviews)

Find out about the history of Gainesville with a stop at Gainesville War Memorial. While you're in the area, find time to visit its casinos.

See properties

Frequently asked questions

What's the area like around Santa Fe Depot Museum?

Santa Fe Depot Museum is located in a welcoming area of Gainesville known for its first-class casinos. If you're looking for a convenient place to stay, take a look at the 17 hotels and other accommodation options you'll find within a mile.

What's the best place to stay near Santa Fe Depot Museum?

Quality Inn Gainesville is one of the top choices for your stay based on our traveller data, and this hotel offers free breakfast and free parking. It's located just a short 0.5 mi (0.9 km) from Santa Fe Depot Museum. Other good options within a short distance include Suburban Studios Gainesville and Holiday Inn Express Hotel & Suites Gainesville by IHG.

How many hotels are there near Santa Fe Depot Museum?

Expedia has 17 hotels and other accommodation options within a mile from Santa Fe Depot Museum.

If I need to cancel the hotel reservation for my stay near Santa Fe Depot Museum, will I receive a refund?

Yes! You'll find that most hotel reservations are fully refundable as long as you cancel before the hotel's cancellation deadline, which often is within 24-48 hours of check in. If you booked a non-refundable reservation, you might be able to cancel it and get a refund within a 24-hour period of booking. Enter your dates, click on "Search", then use the filter option "fully refundable" to review the best deals near Santa Fe Depot Museum.

What can I see and do near Santa Fe Depot Museum?

You can enjoy live performances at Butterfield Stage Players and State Theater. Get outside and spend some time strolling around Leonard Park, Tom Thumb Park and Jaycee Park. Gainesville War Memorial and Frank Buck Zoo are both worth a visit while you're out exploring.

Gainesville Santa Fe Depot Museum Hotels

Change your mind

Treat yourself

Be picky

Check prices for these dates

Filter by

Star rating

Guest rating

Our top choices for Santa Fe Depot Museum hotels

1. The Lancaster Manor B&B

2. Fairfield Inn & Suites by Marriott Gainesville I-35

3. Days Inn by Wyndham Gainesville

4. Holiday Inn Express & Suites Gainesville by IHG

5. Super 8 by Wyndham Gainesville TX

6. Comfort Suites Gainesville

7. Budget Host Motel Gainesville

8. Quality Inn Gainesville

9. Loyalty Inn Gainesville

10. Suburban Studios Gainesville

11. Best Western Red River Inn & Suites

12. Hampton Inn & Suites Gainesville

13. Oak Meadow Ranch

14. La Quinta Inn & Suites by Wyndham Gainesville

15. Lindsay Inn

16. OYO Hotel Valley View TX, I-35

17. Red River Inn And Suites

Compare popular hotels close to Santa Fe Depot Museum

Top Santa Fe Depot Museum Hotel Reviews

La Quinta Inn & Suites by Wyndham Gainesville

Loyalty Inn Gainesville

Fairfield Inn & Suites by Marriott Gainesville I-35

Oak Meadow Ranch

Holiday Inn Express Hotel & Suites Gainesville by IHG

Super 8 by Wyndham Gainesville TX

Budget Host Motel Gainesville

King Ranch -Stay with Puzzles and Jigsaw the Giraffe

Redbud Falls Ranch | Peaceful Horse Ranch Retreat & Private Horse Experiences

Other attractions near Santa Fe Depot Museum

Cooke County Courthouse

Depot Park

Butterfield Stage Players

State Theater

Morton Museum

Tom Thumb Park

Jaycee Park

Gainesville War Memorial

Frequently asked questions