Cartagena Santo Domingo Square Hotels

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Tonight
12 Dec - 13 Dec
Tomorrow
13 Dec - 14 Dec
This weekend
12 Dec - 14 Dec
Next weekend
19 Dec - 21 Dec

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Our top choices for Santo Domingo Square hotels

42-inch LED TV with satellite channels, TV, iPod dock
Hotel Quadrifolio

Hotel Quadrifolio

Hotel Quadrifolio
4.5 star property
Cartagena Centro, 0.2 km from Santo Domingo Square
10.0 out of 10, Exceptional, (163)
"Super cute hotel in the heart of the walled city! Enjoyed the complimentary birthday cake in my room and the staff were super sweet and attentive! Their level of care needs to be studied as it’s hard to find these days. "
United States
Chiron
The price is HK$3,862
HK$3,862 total
11 Jan - 12 Jan 2026
Hotel Quadrifolio
Terrace/patio
Hotel Casa del Gobernador

Hotel Casa del Gobernador

Hotel Casa del Gobernador
4.5 star property
Cartagena Centro, 0.2 km from Santo Domingo Square
9.8 out of 10, Exceptional, (99)
"Beautiful place to stay in historic distric of Cartagena "
United States
Jorge
Hotel Casa del Gobernador
Premium bedding, in-room safe, desk, iron/ironing board
Alfiz Hotel Boutique

Alfiz Hotel Boutique

Alfiz Hotel Boutique
3.0 star property
Cartagena Centro, 0.3 km from Santo Domingo Square
9.6 out of 10, Exceptional, (186)
"This hotel is absolutely lovely, including the employees. They go above and beyond to take care of their guests. We will definitely stay here again!"
United States
Alison
Alfiz Hotel Boutique
Terrace/patio
Sophia Hotel By OxoHotel

Sophia Hotel By OxoHotel

Sophia Hotel By OxoHotel
4.0 star property
Cartagena Centro, 0.2 km from Santo Domingo Square
9.6 out of 10, Exceptional, (601)
"Amazing stay highly recommend "
United States
Michael
Sophia Hotel By OxoHotel
Outdoor pool
Casa La Cartujita

Casa La Cartujita

Casa La Cartujita
4.0 star property
San Diego, 0.5 km from Santo Domingo Square
9.8 out of 10, Exceptional, (171)
"Cute boutique hotel, great room , service and breakfast. "
United States
Kiranmayi
The price is HK$1,154
HK$1,154 total
22 Dec - 23 Dec
Casa La Cartujita
Breakfast, lunch and dinner served
Amarla Boutique Hotel Cartagena

Amarla Boutique Hotel Cartagena

Amarla Boutique Hotel Cartagena
3.5 star property
Cartagena Centro, 0.1 km from Santo Domingo Square
9.6 out of 10, Exceptional, (54)
"The staff was freindly, helpful, gracious ... knew our names throughout our stay. We looked forward to breakfast every day! The ONLY down side was that the pool wasn't open. Otherwise we were comfortable and in awe of the beautiful Amarla."
United States
jennifer
Amarla Boutique Hotel Cartagena
Street view
Hotel Casa La Mantilla by Faranda Boutique

Hotel Casa La Mantilla by Faranda Boutique

Hotel Casa La Mantilla by Faranda Boutique
4.0 star property
Cartagena Centro, < 0.1 km from Santo Domingo Square
9.4 out of 10, Exceptional, (139)
"Very nice, good and quiet hotel. I love it! I recommend it100%"
United States
Andres
The price is HK$1,321
HK$1,321 total
12 Jan - 13 Jan 2026
Hotel Casa La Mantilla by Faranda Boutique
Outdoor pool
Moet Cartagena Hotel Boutique - Adults Only

Moet Cartagena Hotel Boutique - Adults Only

Moet Cartagena Hotel Boutique - Adults Only
4.5 star property
San Diego, 0.3 km from Santo Domingo Square
9.4 out of 10, Exceptional, (95)
"Very friendly and efficient staff Clean property Closed to interest areas"
United States
Luis
Moet Cartagena Hotel Boutique - Adults Only
2 outdoor pools
Casa Claver Loft Boutique Hotel

Casa Claver Loft Boutique Hotel

Casa Claver Loft Boutique Hotel
4.0 star property
Cartagena Centro, 0.2 km from Santo Domingo Square
9.6 out of 10, Exceptional, (577)
"The property was gorgeous and the staff was awesome. Had a great stay. "
United States
Ibrahim
The price is HK$2,230
HK$2,230 total
21 Dec - 22 Dec
Casa Claver Loft Boutique Hotel
Exterior
Movich Hotel Cartagena de Indias

Movich Hotel Cartagena de Indias

Movich Hotel Cartagena de Indias
4.0 star property
Cartagena Centro, 0.2 km from Santo Domingo Square
9.4 out of 10, Exceptional, (551)
"The room was clean and well appointed but just a little bit musty when we entered. I loved the location of this hotel it was near to everything no need for cabs. The staff were very helpful and friendly. The food was just meh, the menu could be more varied especially breakfast. We loved the rooftop restaurant for the view and atmosphere. I would stay there again but just eat out more. "
United States
Desalyn Teresa
The price is HK$3,204
HK$3,204 total
13 Dec - 14 Dec
Movich Hotel Cartagena de Indias
Terrace/patio
Hotel Casa Don Luis by Faranda Boutique, a member of Radisson Individuals

Hotel Casa Don Luis by Faranda Boutique, a member of Radisson Individuals

Hotel Casa Don Luis by Faranda Boutique, a member of Radisson Individuals
4.0 star property
Cartagena Centro, 0.2 km from Santo Domingo Square
9.4 out of 10, Exceptional, (225)
"The staff was great supper friendly and helpful. Breakfast and restaurant was delicious."
United States
Joe
The price is HK$2,311
HK$2,311 total
14 Dec - 15 Dec
Hotel Casa Don Luis by Faranda Boutique, a member of Radisson Individuals
Courtyard
Bastión Luxury Hotel

Bastión Luxury Hotel

Bastión Luxury Hotel
4.5 star property
San Diego, 0.4 km from Santo Domingo Square
9.6 out of 10, Exceptional, (1002)
"Beautiful property "
Canada
Linda
The price is HK$2,076
HK$2,076 total
15 Dec - 16 Dec
Bastión Luxury Hotel
Rooftop terrace
Cinco Quintas Hotel Boutique

Cinco Quintas Hotel Boutique

Cinco Quintas Hotel Boutique
4.0 star property
Cartagena Centro, 0.3 km from Santo Domingo Square
9.4 out of 10, Exceptional, (233)
"Great Place"
Canada
James
The price is HK$1,400
HK$1,400 total
24 Dec - 25 Dec
Cinco Quintas Hotel Boutique
Front of property
Hotel Boutique Casa del Coliseo

Hotel Boutique Casa del Coliseo

Hotel Boutique Casa del Coliseo
4.5 star property
Cartagena Centro, 0.3 km from Santo Domingo Square
9.4 out of 10, Exceptional, (304)
"The staff was very helpful. "
United States
thomas
The price is HK$1,915
HK$1,915 total
17 Dec - 18 Dec
Hotel Boutique Casa del Coliseo
Exterior
Casa del Arzobispado Hotel

Casa del Arzobispado Hotel

Casa del Arzobispado Hotel
4.0 star property
Cartagena Centro, 0.2 km from Santo Domingo Square
9.4 out of 10, Exceptional, (320)
"Fantastic staff and very friendly, very close to everything "
Canada
Sahar
Casa del Arzobispado Hotel
Daily cooked-to-order breakfast (COP 45000 per person)
Casa Noa Colonial Rooms

Casa Noa Colonial Rooms

Casa Noa Colonial Rooms
2.5 star property
Cartagena Centro, 0.3 km from Santo Domingo Square
9.2 out of 10, Wonderful, (163)
"Very nice, clean, friendly staff and great location!!"
United States
Brooke
The price is HK$714
HK$714 total
24 Dec - 25 Dec
Casa Noa Colonial Rooms
Free daily buffet breakfast
Charleston Santa Teresa Cartagena

Charleston Santa Teresa Cartagena

Charleston Santa Teresa Cartagena
5.0 star property
Cartagena Centro, 0.3 km from Santo Domingo Square
9.4 out of 10, Exceptional, (779)
"Excellent service, food and amenities "
United States
Alejandra
The price is HK$2,671
HK$2,671 total
15 Dec - 16 Dec
Charleston Santa Teresa Cartagena
Dining room
Upper House

Upper House

Upper House
2.5 star property
Cartagena Walled City, 0.5 km from Santo Domingo Square
9.4 out of 10, Exceptional, (48)
"Super nice place :)"
United States
Samuel
The price is HK$802
HK$810 total
16 Dec - 17 Dec
Upper House
Front of property
Hotel Santa Catalina By OxoHotel

Hotel Santa Catalina By OxoHotel

Hotel Santa Catalina By OxoHotel
4.0 star property
Cartagena Centro, 0.3 km from Santo Domingo Square
9.2 out of 10, Wonderful, (1002)
"Great Location at the heart of Cartagena, unique service and amazing Food. The bed is very confortable, Specially the pillows, and the rooftop is very Nice"
United States
Jose
The price is HK$1,718
HK$1,718 total
8 Jan - 9 Jan 2026
Hotel Santa Catalina By OxoHotel
Terrace/patio
Terrazas Hotel Boutique

Terrazas Hotel Boutique

Terrazas Hotel Boutique
5.0 star property
La Matuna, 0.4 km from Santo Domingo Square
9.4 out of 10, Exceptional, (56)
"Small place, but nice"
United States
Jorge
The price is HK$1,142
HK$1,142 total
21 Dec - 22 Dec
Terrazas Hotel Boutique
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Santo Domingo Square Hotel Reviews

Hotel Santa Catalina By OxoHotel

Hotel Santa Catalina By OxoHotel

10/10 Excellent
"Estoy muy contento de haber podido seleccionar su hotel para el ironman. Gracias todo fue super."
Ruben 7-night trip
Posted 1 day ago
Hotel Santa Catalina By OxoHotel

Hotels near other Santo Domingo Square attractions

Templo de Santo Domingo

Templo de Santo Domingo is just one of the places to see in Cartagena, so why not enjoy the other things to explore during your travels? Stroll along the beautiful beaches or seek out the local tours.
See properties

Botero's Mujer Reclinada

You can learn about the history of Cartagena with a visit to Botero's Mujer Reclinada. Stroll along the beautiful beaches or seek out the local tours.
See properties

Frequently asked questions

What's the area like around Santo Domingo Square?
Santo Domingo Square is located in a historic area of Cartagena known for its beautiful beaches. If you're looking for a convenient place to stay, take a look at the 1151 hotels and other accommodation options you'll find within a mile.
What's the best hotel to stay near Santo Domingo Square?
Adjacent to Santo Domingo Square, Hotel Santa Catalina By OxoHotel is one of the top choices for your stay based on our traveller data, and this hotel offers free breakfast and a restaurant. Other good choices within a short distance include Hyatt Regency Cartagena and Osh Hotel Cartagena.
How many hotels are there close to Santo Domingo Square?
Expedia has 1151 hotels and other accommodation options within a mile from Santo Domingo Square.
If I need to cancel the hotel reservation for my stay near Santo Domingo Square, will I receive a refund?
Yes! The majority of room reservations are refundable provided that you cancel prior to the accommodation's cancellation deadline, which in most cases is within 24 or 48 hours of check in. If you booked a non-refundable reservation, it might still be possible to cancel it and be given a refund within a 24-hour period of your booking. Put your dates in and click on "Search", then use the "fully refundable" filter to get the top deals on offer near Santo Domingo Square.
What can I see and do near Santo Domingo Square?
Study the collections at Palace of the Inquisition Cartagena Historical Museum, Bastion of Santiago or Palacio de la Inquisicion. Cartagena Cathedral, Plaza Santo Domingo and San Pedro Claver Church and Convent are monuments to see when you're exploring the area around Santo Domingo Square. You can enjoy live performances at Teatro Heredia and Ciudad Movil Cultural Center.

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