A large lake surrounded by dense forests.

Downtown hotels in Seneca

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Check prices for these dates

This weekend
30 Oct - 1 Nov
Next weekend
6 Nov - 8 Nov

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Our top choices for Downtown hotels

A poolside area with outdoor seating and a view of a lake and forested hills.

1. Fairfield Inn & Suites Seneca Clemson Univ Area

Fairfield Inn & Suites Seneca Clemson Univ Area
3.0 star property
2 km from Downtown
9.2 out of 10, Wonderful, (289 reviews)
"Excellent in every way!"
United States
Bonnie
The price is HK$941
HK$1,035 total
includes taxes & fees
8 Nov - 9 Nov
Fairfield Inn & Suites Seneca Clemson Univ Area
A hotel dining area with a long table, multiple chairs, and a bar in the background.

2. Hampton Inn & Suites Seneca-Clemson Area

Hampton Inn & Suites Seneca-Clemson Area
2.5 star property
2.2 km from Downtown
9.2 out of 10, Wonderful, (764 reviews)
"Room was clean and staff was friendly and helpful."
United States
Sasha
The price is HK$960
HK$1,056 total
includes taxes & fees
29 Nov - 30 Nov
Hampton Inn & Suites Seneca-Clemson Area
A hotel room with a bed, a desk, a chair, a large window with curtains, a bathroom with a bathtub, and a flat-screen TV.

3. Best Western Seneca-Clemson

Best Western Seneca-Clemson
2.5 star property
1.7 km from Downtown
8.4 out of 10, Very good, (697 reviews)
"The room was clean and had no odors. But the place is seriously dated even though it was clean."
United States
Greg
The price is HK$760
HK$836 total
includes taxes & fees
30 Nov - 1 Dec
Best Western Seneca-Clemson
A restaurant interior with a counter, seating area, and a TV mounted on the wall.

4. Quality Inn Seneca US-123

Quality Inn Seneca US-123
2.5 star property
3.8 km from Downtown
8.0 out of 10, Very good, (766 reviews)
"Clean rooms clean parking area nice staff all good"
United States
Barry
The price is HK$664
HK$779 total
includes taxes & fees
5 Nov - 6 Nov
Quality Inn Seneca US-123
An outdoor patio area with a fire pit, seating, and string lights.

5. Tru by Hilton Seneca Clemson

Tru by Hilton Seneca Clemson
2.5 star property
8.4 km from Downtown
9.2 out of 10, Wonderful, (901 reviews)
"Great stay!"
United States
Melissa
The price is HK$798
HK$877 total
includes taxes & fees
19 Nov - 20 Nov
Tru by Hilton Seneca Clemson
A modern dining area with a high ceiling, large windows, and a buffet setup.

6. Days Inn by Wyndham Seneca / Clemson Area

Days Inn by Wyndham Seneca / Clemson Area
2.0 star property
3.1 km from Downtown
6.8 out of 10, (792 reviews)
"Very clean room, recently renovated. Comfy bed!"
United States
Rhiannon
The price is HK$594
HK$653 total
includes taxes & fees
30 Nov - 1 Dec
Days Inn by Wyndham Seneca / Clemson Area
A multi-level interior with a spiral staircase, wooden railings, and a seating area with tables and chairs.

7. The Shepherd Hotel Downtown Clemson

The Shepherd Hotel Downtown Clemson
4.0 star property
10.6 km from Downtown
9.8 out of 10, Exceptional, (903 reviews)
"Always a wonderful stay!"
United States
Laurrie
The price is HK$1,640
HK$1,820 total
includes taxes & fees
1 Nov - 2 Nov
The Shepherd Hotel Downtown Clemson
A Holiday Inn Express hotel with a stone facade, large windows, and a parking lot.

8. Holiday Inn Express & Suites Clemson by IHG

Holiday Inn Express & Suites Clemson by IHG
2.5 star property
12.4 km from Downtown
8.8 out of 10, Excellent, (998 reviews)
"Wonderful place to stay."
United States
John
The price is HK$1,012
HK$1,123 total
includes taxes & fees
1 Nov - 2 Nov
Holiday Inn Express & Suites Clemson by IHG
A modern kitchen with a microwave, coffee maker, and bar stools.

9. Comfort Inn & Suites Clemson - University Area

Comfort Inn & Suites Clemson - University Area
2.5 star property
11.7 km from Downtown
8.4 out of 10, Very good, (1,002 reviews)
"Clean, walkable to downtown!"
United States
melissa
The price is HK$794
HK$881 total
includes taxes & fees
29 Nov - 30 Nov
Comfort Inn & Suites Clemson - University Area
A modern bar area with a menu board, bar stools, and a countertop with various items.

10. Courtyard Marriott Clemson

Courtyard Marriott Clemson
3.0 star property
12.9 km from Downtown
9.0 out of 10, Wonderful, (591 reviews)
"The staff were so friendly and accommodating. The property was very clean and room was spacious."
United States
kim
The price is HK$810
HK$899 total
includes taxes & fees
22 Nov - 23 Nov
Courtyard Marriott Clemson
A modern lounge area with a brick accent wall, a fireplace, and comfortable seating.

11. The Abernathy of Clemson

The Abernathy of Clemson
4.0 star property
10.1 km from Downtown
9.6 out of 10, Exceptional, (657 reviews)
"Great place."
United States
John
The price is HK$1,193
HK$1,325 total
includes taxes & fees
15 Nov - 16 Nov
The Abernathy of Clemson
A modern kitchen area with a bar counter and seating.

12. Hampton Inn Clemson-University Area

Hampton Inn Clemson-University Area
2.5 star property
9.8 km from Downtown
8.8 out of 10, Excellent, (652 reviews)
"Staff was great especially Crystal. Breakfast was fine. A little hidden by trees so watch out or you could miss entrance. Also, driveway just a little steep to get into lot but once there everything was fine. "
United States
Blaise
The price is HK$860
HK$955 total
includes taxes & fees
7 Nov - 8 Nov
Hampton Inn Clemson-University Area
A spacious indoor dining area with multiple tables and chairs, a food service counter, and a modern architectural design with balconies.

13. Best Western Plus Clemson Hotel & Conference Center

Best Western Plus Clemson Hotel & Conference Center
2.5 star property
11.8 km from Downtown
8.0 out of 10, Very good, (1,003 reviews)
"I have stayed here several times and it has always been a great experience. The rooms are clean and the staff is friendly."
United States
Alyssa
The price is HK$794
HK$881 total
includes taxes & fees
30 Nov - 1 Dec
Best Western Plus Clemson Hotel & Conference Center
A multi-story hotel with a swimming pool, landscaped grounds, and a parking area.

14. Lakeside Lodge Clemson

Lakeside Lodge Clemson
2.5 star property
8.6 km from Downtown
9.0 out of 10, Wonderful, (1,000 reviews)
"Friendly front desk and bar staff. We had a really nice overnight stay."
United States
Sherry
The price is HK$855
HK$1,062 total
includes taxes & fees
3 Nov - 4 Nov
Lakeside Lodge Clemson
A golf course with a water body, trees, and a distant view of a bridge.

15. Clemson University's James F. Martin Inn

Clemson University's James F. Martin Inn
3.0 star property
10.3 km from Downtown
9.4 out of 10, Exceptional, (1,005 reviews)
"Great property!"
United States
Lilllian
The price is HK$1,091
HK$1,211 total
includes taxes & fees
30 Nov - 1 Dec
Clemson University's James F. Martin Inn
A kitchen with a coffee maker, microwave, and refrigerator.

16. Rodeway Inn & Suites Walhalla

Rodeway Inn & Suites Walhalla
2.0 star property
12.8 km from Downtown
7.6 out of 10, Good, (199 reviews)
"The room was clean and the bed was comfortable"
United States
Donna
The price is HK$627
HK$699 total
includes taxes & fees
28 Nov - 29 Nov
Rodeway Inn & Suites Walhalla
A reception area with a reception desk, a sofa, a staircase, and a wall with artwork.

17. Inn @ Clemson

Inn @ Clemson
2.5 star property
11.6 km from Downtown
8.0 out of 10, Very good, (1,010 reviews)
"Clean room, comfortable beds, good breakfast, great price!"
United States
Kristi
The price is HK$628
HK$698 total
includes taxes & fees
1 Nov - 2 Nov
Inn @ Clemson
A dining area with a table and chairs, large windows with a view of the outside, and a green sofa.

18. Days Inn by Wyndham Clemson

Days Inn by Wyndham Clemson
3.5 star property
12.5 km from Downtown
6.8 out of 10, (237 reviews)
"While the hotel is close to Clemson, the property/ rooms were GROSS!! The bathroom had been wiped down, but whoever cleaned it missed the soap and shampoo left up top on the rim. The AC smelt so strongly of mildew/ mold that we could NOT turn it on. The whole room smelled like wet towels"
United States
Stephanie
The price is HK$663
HK$736 total
includes taxes & fees
1 Nov - 2 Nov
Days Inn by Wyndham Clemson
A cabin with a cozy interior, a wooden exterior, and a view of the forest.

19. Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott Bonvoy

Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott Bonvoy
2.0 star property
7.5 km from Downtown
9.8 out of 10, Exceptional, (116 reviews)
"My wife and I enjoyed our stay here. 10/10 experience."
United States
Winston
The price is HK$659
HK$1,070 total
includes taxes & fees
30 Nov - 1 Dec
Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott Bonvoy
A spacious hallway with a wooden ceiling, a sofa, a chair, and a lamp.

20. The Inn at Patrick Square

The Inn at Patrick Square
3.5 star property
15.2 km from Downtown
9.8 out of 10, Exceptional, (935 reviews)
"Lovely place to stay."
United States
Jennifer
The price is HK$1,169
HK$1,298 total
includes taxes & fees
1 Nov - 2 Nov
The Inn at Patrick Square
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

Compare popular hotels in Downtown

Property
Property class
Guest rating
Breakfast included
Pool
Spa
Pet-friendly
WiFi included
A poolside area with outdoor seating and a view of a lake and forested hills.
Fairfield Inn & Suites Seneca Clemson Univ Area
3.0 star property
9.2
Wonderful
289 reviews
View
A hotel dining area with a long table, multiple chairs, and a bar in the background.
Hampton Inn & Suites Seneca-Clemson Area
2.5 star property
9.2
Wonderful
764 reviews
View
An outdoor patio area with a fire pit, seating, and string lights.
Tru by Hilton Seneca Clemson
2.5 star property
9.2
Wonderful
901 reviews
View
A hotel room with a bed, a desk, a chair, a large window with curtains, a bathroom with a bathtub, and a flat-screen TV.
Best Western Seneca-Clemson
2.5 star property
8.4
Very good
697 reviews
View
A multi-level interior with a spiral staircase, wooden railings, and a seating area with tables and chairs.
The Shepherd Hotel Downtown Clemson
4.0 star property
9.8
Exceptional
903 reviews
View

Hotels recommended for families in Downtown

A hallway with a wooden floor, a large mirror, and framed pictures on the walls.

Boutique hotel in historic downtown Seneca. Room #5, two King beds.

Boutique hotel in historic downtown Seneca. Room #5, two King beds.
Downtown
9.0 out of 10, Wonderful, (22)
The price is HK$988
HK$1,600 total
includes taxes & fees
2 Nov - 3 Nov
Boutique hotel in historic downtown Seneca. Room #5, two King beds.

Where to stay in Downtown

Find the best Downtown areas for the activities you enjoy most.
A sunset over a lake surrounded by dense forests and residential areas.

Serenity Bay

When in Serenity Bay, you can plan a visit to Keowee Key Golf Course and Lake Keowee, some noteworthy sights in the nearby area.

A sunset over a calm lake with a kayaker and a large tree on the shore.

Pine Ridge Point

If you're looking for some top things to see and do in Pine Ridge Point and surrounding area, you can visit South Beach and Lake Keowee.

Indian Oaks

While Indian Oaks may not have many sights to explore, venturing just a little farther will lead you to top things to see and do like Oconee County Library Seneca Branch and Keowee Reservoir.

Keowee Plantation

While Keowee Plantation isn't home to many top sights, Oconee County Library Seneca Branch and Keowee Reservoir are some notable places to visit nearby.

Top Downtown Hotel Reviews

Lakeside Lodge Clemson

Lakeside Lodge Clemson

8/10 Good
"The photos make the property seem much more luxurious and big. It was a nice hotel. But I wouldn’t go thinking I’m having an amazing vacation."
Wendy 1-night trip
Posted 2 days ago
Lakeside Lodge Clemson

Frequently asked questions

What is Downtown like?
Travellers to the Downtown neighbourhood in Seneca will be sure to enjoy their stay. Make sure that you visit Oconee County Library Seneca Branch and Blue Ridge Arts Center as part of your Downtown travel plans.
Where is the best place to stay in Downtown?
For your stay in Downtown, Historic Seneca Bungalow is one of the top choices based on our traveller data.
How many hotels will I be able to find in Downtown?
If you're searching for places to stay in Seneca, choose from one of Expedia's 12 hotels and other accommodation options in Downtown.
If I need to cancel my hotel reservation in Downtown, will I receive a refund?
Yes! You'll find that most room reservations are refundable if you cancel prior to the hotel's cancellation deadline, which is usually within 24-48 hours of your check-in date. If your reservation is non-refundable, you might be able to still cancel and receive a refund within 24 hours of booking. Enter your dates, click on "Search", then use the filter option "fully refundable" to review the best deals in Downtown.
What can I see and do in this Seneca neighbourhood?
Oconee County Library Seneca Branch, Blue Ridge Arts Center and Seneca Historic District are just a few attractions to check out in Downtown. As you're discovering the neighbourhood, Bertha Lee Strickland Cultural Museum and The Gauntlet are some other places worth a visit. Seneca City Hall, Golden Corner Plaza and Oconee Community Theatre are just a few of the places to visit in and around Downtown. While you're out sightseeing in Seneca, make sure that you visit other sights such as Applewood Shopping Center or Wyndham Plaza.