Siesta Isle hotels in Fort Myers Beach

  • Change your mind

    Book hotels with free cancellation
  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
  • Be picky

    Search almost a million properties worldwide

Check prices for these dates

Filter by

Guest rating
Guest rating
Star rating

Our top choices for Siesta Isle hotels

Latitude 26 Waterfront Boutique Resort - Fort Myers Beach

Latitude 26 Waterfront Boutique Resort - Fort Myers Beach
2.5 star property
Siesta Isle
8.8 out of 10, Excellent, (1,001 reviews)
"Great stay"
United States
Andrea
The price is HK$1,982
HK$2,210 total
includes taxes & fees
7 Mar - 8 Mar
Latitude 26 Waterfront Boutique Resort - Fort Myers Beach

The Perry Hotel Naples

The Perry Hotel Naples
4.5 star property
26.4 km from Siesta Isle
9.6 out of 10, Exceptional, (636 reviews)
"Friendly, helpful staff Great location excellent restaurant"
United States
Alan
The price is HK$2,495
HK$3,160 total
includes taxes & fees
22 Feb - 23 Feb
The Perry Hotel Naples

MainStay Suites Fort Myers East I-75

MainStay Suites Fort Myers East I-75
2.5 star property
25.4 km from Siesta Isle
9.6 out of 10, Exceptional, (270 reviews)
"Large rooms, great rates, great breakfast and a convenient location. "
Canada
Fraser
The price is HK$1,231
HK$1,373 total
includes taxes & fees
1 Mar - 2 Mar
MainStay Suites Fort Myers East I-75

Lani Kai Beachfront Resort

Lani Kai Beachfront Resort
3.5 star property
2.7 km from Siesta Isle
9.0 out of 10, Wonderful, (1,234 reviews)
"Nice place to stay"
United States
Denise
The price is HK$2,463
HK$2,921 total
includes taxes & fees
16 Feb - 17 Feb
Lani Kai Beachfront Resort

Comfort Suites Fort Myers East I-75

Comfort Suites Fort Myers East I-75
2.5 star property
25.5 km from Siesta Isle
9.6 out of 10, Exceptional, (404 reviews)
"Good hotel for the price "
United Kingdom
Paul
The price is HK$1,165
HK$1,299 total
includes taxes & fees
22 Feb - 23 Feb
Comfort Suites Fort Myers East I-75

Shalimar Beach Resort

Shalimar Beach Resort
2.0 star property
14.4 km from Siesta Isle
10.0 out of 10, Exceptional, (28 reviews)
"Everything about this place was great "
United States
Andrew
The price is HK$5,022
HK$5,600 total
includes taxes & fees
17 Feb - 18 Feb
Shalimar Beach Resort

TownePlace Suites by Marriott Fort Myers Gulf Coast

TownePlace Suites by Marriott Fort Myers Gulf Coast
3.0 star property
15.9 km from Siesta Isle
9.4 out of 10, Exceptional, (143 reviews)
"Everything about the stay in was beautiful "
United States
Jameasha
The price is HK$1,751
HK$1,952 total
includes taxes & fees
22 Feb - 23 Feb
TownePlace Suites by Marriott Fort Myers Gulf Coast

Casa Ybel Resort

Casa Ybel Resort
2.5 star property
12.8 km from Siesta Isle
8.6 out of 10, Excellent, (302 reviews)
"Clean rooms, great staff, beautiful view "
United States
Julia
The price is HK$6,167
HK$6,877 total
includes taxes & fees
22 Feb - 23 Feb
Casa Ybel Resort

Park Motel

Park Motel
2.5 star property
24.7 km from Siesta Isle
9.6 out of 10, Exceptional, (28 reviews)
"Clean, quiet, very friendly and helpful staff, hot tub in room very relaxing."
United States
Kristeen
The price is HK$779
HK$869 total
includes taxes & fees
16 Feb - 17 Feb
Park Motel

Tween Waters Island Resort & Spa

Tween Waters Island Resort & Spa
3.0 star property
23.6 km from Siesta Isle
8.6 out of 10, Excellent, (1,004 reviews)
"Lovely location, pools and restaurants."
United States
Linda
The price is HK$2,532
HK$3,097 total
includes taxes & fees
6 Mar - 7 Mar
Tween Waters Island Resort & Spa

Sanibel Island Beach Resort

Sanibel Island Beach Resort
3.0 star property
10.1 km from Siesta Isle
9.2 out of 10, Wonderful, (1,608 reviews)
"Staff is amazing, amenities are great and is so beautiful! "
United States
Erica
The price is HK$3,193
HK$3,756 total
includes taxes & fees
4 Mar - 5 Mar
Sanibel Island Beach Resort

Best Western Plus Beach Resort

Best Western Plus Beach Resort
2.5 star property
2.2 km from Siesta Isle
9.4 out of 10, Exceptional, (1,001 reviews)
"Very clean and it had everything we needed. Friendly staff and a great view from the room. "
United States
Richard
The price is HK$3,746
HK$4,176 total
includes taxes & fees
11 Mar - 12 Mar
Best Western Plus Beach Resort

Holiday Inn Express & Suites Fort Myers Airport by IHG

Holiday Inn Express & Suites Fort Myers Airport by IHG
2.5 star property
17.9 km from Siesta Isle
9.6 out of 10, Exceptional, (1,006 reviews)
"Nice room, nice staff, great airport shuttle "
United States
Amy
The price is HK$1,391
HK$1,551 total
includes taxes & fees
1 Mar - 2 Mar
Holiday Inn Express & Suites Fort Myers Airport by IHG

Woodspring Suites Fort Myers - Cape Coral

Woodspring Suites Fort Myers - Cape Coral
2.5 star property
15.9 km from Siesta Isle
7.4 out of 10, Good, (203 reviews)
"The room was new, high quality and staff was excellent!"
United States
Brian
The price is HK$696
HK$776 total
includes taxes & fees
16 Feb - 17 Feb
Woodspring Suites Fort Myers - Cape Coral

Sanibel Inn

Sanibel Inn
3.0 star property
9 km from Siesta Isle
9.0 out of 10, Wonderful, (1,002 reviews)
"Perfect place if you are looking for a quiet and safe environment! "
United States
Rachelle
The price is HK$4,522
HK$5,538 total
includes taxes & fees
26 Feb - 27 Feb
Sanibel Inn

Comfort Inn & Suites Fort Myers Airport

Comfort Inn & Suites Fort Myers Airport
2.5 star property
18.1 km from Siesta Isle
8.8 out of 10, Excellent, (1,126 reviews)
"Always a great stay here. "
United States
Kirk
The price is HK$1,330
HK$1,483 total
includes taxes & fees
16 Feb - 17 Feb
Comfort Inn & Suites Fort Myers Airport

Latitude 26 Waterfront Boutique Resort - Bonita Springs

Latitude 26 Waterfront Boutique Resort - Bonita Springs
3.0 star property
20.4 km from Siesta Isle
8.8 out of 10, Excellent, (727 reviews)
"Adorable place and great spot near the beach. Enjoyed our stay amd look forward to coming back. "
United States
Michelle
The price is HK$2,652
HK$3,023 total
includes taxes & fees
7 Mar - 8 Mar
Latitude 26 Waterfront Boutique Resort - Bonita Springs

Fairways Inn of Naples

Fairways Inn of Naples
3.0 star property
28.6 km from Siesta Isle
9.4 out of 10, Exceptional, (1,205 reviews)
"Clean room and staff was very friendly."
United States
shera
The price is HK$1,482
HK$1,645 total
includes taxes & fees
5 Mar - 6 Mar
Fairways Inn of Naples

Days Inn & Suites by Wyndham Fort Myers Near JetBlue Park

Days Inn & Suites by Wyndham Fort Myers Near JetBlue Park
2.0 star property
18.4 km from Siesta Isle
8.0 out of 10, Very good, (1,584 reviews)
"Good room for a fair price in a good location "
United States
John
The price is HK$851
HK$949 total
includes taxes & fees
22 Feb - 23 Feb
Days Inn & Suites by Wyndham Fort Myers Near JetBlue Park

Quality Inn Fort Myers Cape Coral

Quality Inn Fort Myers Cape Coral
2.0 star property
15.3 km from Siesta Isle
7.6 out of 10, Good, (222 reviews)
"Clean room and staff was excellent "
Canada
SURINDER
The price is HK$707
HK$914 total
includes taxes & fees
22 Feb - 23 Feb
Quality Inn Fort Myers Cape Coral
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Where to stay in Siesta Isle

Find the best Siesta Isle areas for the activities you enjoy most.

Mid Island

While visiting Mid Island, you might make a stop by sights like Estero Boulevard Beach and Sterling Ave Beach.

South Island

While visiting South Island, you might make a stop by sights like Santini Marina Shopping Plaza and Castle Beach.

TP Hill's

When in TP Hill's, you can plan a visit to Key West Express and Estero Boulevard Beach, some noteworthy sights in the nearby area.

Downtown Fort Myers Beach

If you're spending some time in Downtown Fort Myers Beach, Lynn Hall Memorial Park and Estero Boulevard Beach are top sights worth seeing.

Laguna Shores

While Laguna Shores may not have many sights to explore, venturing just a little farther will lead you to top things to see and do like Lover's Key Beach and Santini Marina Shopping Plaza.

Top Siesta Isle Hotel Reviews

Frequently asked questions

What is Siesta Isle like?
Travellers will be sure to find plenty to entertain them in Fort Myers Beach's Siesta Isle neighbourhood. Consider a visit to San Carlos Bay - Bunche Beach Preserve as part of your Siesta Isle travel plans.
Where is the best place to stay in Siesta Isle?
Based on Expedia customer reviews, Latitude 26 Waterfront Boutique Resort - Fort Myers Beach is the highest ranked property in Siesta Isle. This hotel offers a marina and free breakfast.
How many hotels will I find in the Siesta Isle area?
When you want to put your feet up after a day of exploring the sights in Fort Myers Beach, you can choose from 18 Expedia hotels and other accommodation options in Siesta Isle.
If I need to cancel my hotel reservation in Siesta Isle, will I receive a refund?
Yes! You'll find that most hotel reservations are refundable provided that you cancel prior to the accommodation's cancellation deadline, which is usually within 24-48 hours of your check-in date. If you booked a non-refundable reservation, it may still be possible to cancel it and be given a refund within a 24-hour period of your booking. Enter your dates, click on "Search", then use the "fully refundable" filter to view the best deals in Siesta Isle.
What are the top things to see and do in Siesta Isle?
San Carlos Bay - Bunche Beach Preserve is an attraction you might want to check out while you're in Siesta Isle. Key West Express and Bunche Beach are also worth a visit when you're out sightseeing in Fort Myers Beach.

Explore a world of travel with Expedia