Photo by Bill Dillard

Southeast Missouri hotels from HK$459
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Our top choices for Southeast Missouri hotels

Fairfield Inn & Suites by Marriott Poplar Bluff
Fairfield Inn & Suites by Marriott Poplar BluffPoplar Bluff
9.4 out of 10, Exceptional, (887 reviews)
The price is HK$861
HK$973 total
includes taxes & fees
26 Apr - 27 Apr

Drury Inn & Suites Sikeston, MO
Drury Inn & Suites Sikeston, MOSikeston
9.4 out of 10, Exceptional, (1,004 reviews)
The price is HK$869
HK$999 total
includes taxes & fees
20 Apr - 21 Apr

Honeysuckle Inn - Mountain View
Honeysuckle Inn - Mountain ViewMountain View
8.6 out of 10, Excellent, (344 reviews)
The price is HK$747
HK$810 total
includes taxes & fees
13 Apr - 14 Apr

Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG
Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHGCape Girardeau
9.4 out of 10, Exceptional, (1,001 reviews)
The price is HK$822
HK$928 total
includes taxes & fees
19 Apr - 20 Apr

Hampton Inn Sikeston
Hampton Inn SikestonSikeston
9.0 out of 10, Wonderful, (531 reviews)
The price is HK$829
HK$938 total
includes taxes & fees
9 May - 10 May

Fairfield Inn & Suites by Marriott Sikeston
Fairfield Inn & Suites by Marriott SikestonSikeston
9.4 out of 10, Exceptional, (69 reviews)
The price is HK$861
HK$975 total
includes taxes & fees
30 Apr - 1 May

Drury Plaza Hotel Cape Girardeau Conference Center
Drury Plaza Hotel Cape Girardeau Conference CenterCape Girardeau
9.6 out of 10, Exceptional, (1,004 reviews)
The price is HK$783
HK$883 total
includes taxes & fees
3 May - 4 May

La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau
La Quinta Inn & Suites by Wyndham Jackson/Cape GirardeauJackson
9.0 out of 10, Wonderful, (743 reviews)
The price is HK$698
HK$755 total
includes taxes & fees
13 Apr - 14 Apr

Echo Bluff State Park
Echo Bluff State ParkEminence
9.6 out of 10, Exceptional, (237 reviews)
The price is HK$1,297
HK$1,371 total
includes taxes & fees
14 Apr - 15 Apr

Hampton Inn Poplar Bluff
Hampton Inn Poplar BluffPoplar Bluff
9.4 out of 10, Exceptional, (816 reviews)
The price is HK$732
HK$820 total
includes taxes & fees
19 Apr - 20 Apr

Crown Pointe Lodge, BW Signature Collection
Crown Pointe Lodge, BW Signature CollectionFarmington
9.0 out of 10, Wonderful, (605 reviews)
The price is HK$792
HK$902 total
includes taxes & fees
26 Apr - 27 Apr

Drury Inn & Suites Jackson MO
Drury Inn & Suites Jackson MOJackson
9.6 out of 10, Exceptional, (1,007 reviews)
The price is HK$642
HK$679 total
includes taxes & fees
30 Apr - 1 May

Pear Tree Inn Cape Girardeau West
Pear Tree Inn Cape Girardeau WestCape Girardeau
9.0 out of 10, Wonderful, (1,004 reviews)
The price is HK$564
HK$636 total
includes taxes & fees
23 Apr - 24 Apr

Holiday Inn Express & Suites Perryville by IHG
Holiday Inn Express & Suites Perryville by IHGPerryville
9.2 out of 10, Wonderful, (578 reviews)
The price is HK$791
HK$905 total
includes taxes & fees
19 Apr - 20 Apr

Super 8 by Wyndham Perryville
Super 8 by Wyndham PerryvillePerryville
8.4 out of 10, Very good, (977 reviews)
The price is HK$499
HK$571 total
includes taxes & fees
30 Apr - 1 May

Fairfield Inn & Suites by Marriott Cape Girardeau
Fairfield Inn & Suites by Marriott Cape GirardeauCape Girardeau
9.4 out of 10, Exceptional, (173 reviews)
The price is HK$659
HK$743 total
includes taxes & fees
26 Apr - 27 Apr

Drury Inn & Suites Poplar Bluff
Drury Inn & Suites Poplar BluffPoplar Bluff
9.2 out of 10, Wonderful, (1,003 reviews)
The price is HK$791
HK$894 total
includes taxes & fees
3 May - 4 May

The Riverview
The RiverviewCape Girardeau
9.4 out of 10, Exceptional, (545 reviews)
The price is HK$912
HK$1,029 total
includes taxes & fees
14 Apr - 15 Apr

Hampton Inn Cape Girardeau I 55 East
Hampton Inn Cape Girardeau I 55 EastCape Girardeau
9.6 out of 10, Exceptional, (803 reviews)
The price is HK$828
HK$934 total
includes taxes & fees
3 May - 4 May

Holiday Inn Poplar Bluff by IHG
Holiday Inn Poplar Bluff by IHGPoplar Bluff
8.8 out of 10, Excellent, (728 reviews)
The price is HK$791
HK$894 total
includes taxes & fees
19 Apr - 20 Apr
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Holiday Rentals in Southeast Missouri
Cabin

Postcard Cabins St Francois, Outdoor Collection by Marriott Bonvoy
Postcard Cabins St Francois, Outdoor Collection by Marriott BonvoyFrench Village
9.8 out of 10, Exceptional, (58 reviews)
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Stay near popular Southeast Missouri attractions
Learn more about Southeast Missouri
Discover the family-friendly area of Southeast Missouri—wineries, a scenic riverfront and sights from Sam A. Baker State Park to K Bridge Recreation Area.

Photo by Bill Dillard
Open Photo by Bill Dillard
More cheap stays in Southeast Missouri

Baymont Inn and Suites by Wyndham Farmington, MO
1625 W Columbia St Farmington MO
The price is HK$470 per night from 29 Apr to 30 Apr
HK$470
HK$535 total
29 Apr - 30 Apr
includes taxes & fees
8/10 Very Good! (1,003 reviews)
Hotels in Southeast Missouri with star-rating

4 Star Hotels
2 properties
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