Vatican Luxury Hotel

Start date: Check-in selected.
To Date
End date: Check-out

  • Change your mind

    Book hotels with free cancellation

  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in

  • Be picky

    Search almost a million properties worldwide

Check availability on Vatican Luxury Hotel

Our top choices for Vatican luxury hotels

Rooftop terrace
The First Musica - Preferred Hotels & Resorts

The First Musica - Preferred Hotels & Resorts

The First Musica - Preferred Hotels & Resorts
5.0 star property
Rome City Centre
9.6 out of 10, Exceptional, (102)
"Excellent location, amazing staff, "
United States
Adelia
The price is HK$2,709
HK$3,163 total
includes taxes & fees
10 Jan - 11 Jan 2026
The First Musica - Preferred Hotels & Resorts
Outdoor pool, pool umbrellas, pool loungers
Villa Agrippina Gran Meliá - The Leading Hotels of the World

Villa Agrippina Gran Meliá - The Leading Hotels of the World

Villa Agrippina Gran Meliá - The Leading Hotels of the World
5.0 star property
Rome City Centre
9.2 out of 10, Wonderful, (935)
"Beautiful hotel, very clean, staff so friendly and helpful Would definitely stay again!"
United Kingdom
debra jane
The price is HK$3,672
HK$4,222 total
includes taxes & fees
8 Jan - 9 Jan 2026
Villa Agrippina Gran Meliá - The Leading Hotels of the World
Aerial view
Hotel Dei Mellini

Hotel Dei Mellini

Hotel Dei Mellini
4.0 star property
Rome City Centre
9.2 out of 10, Wonderful, (1001)
"Clean, great staff, great location "
United States
Marigona
The price is HK$2,092
HK$2,439 total
includes taxes & fees
7 Jan - 8 Jan 2026
Hotel Dei Mellini
Hypo-allergenic bedding, free minibar items, in-room safe, desk
Le Méridien Visconti Rome

Le Méridien Visconti Rome

Le Méridien Visconti Rome
4.0 star property
Rome City Centre
8.8 out of 10, Excellent, (1000)
"Great hotel, convenient location."
Mexico
Edgar
The price is HK$1,705
HK$2,012 total
includes taxes & fees
11 Jan - 12 Jan 2026
Le Méridien Visconti Rome
Rooftop terrace
Orazio Palace Hotel

Orazio Palace Hotel

Orazio Palace Hotel
4.0 star property
Rome City Centre
9.4 out of 10, Exceptional, (231)
"Great hotel and location for the price. Staff is very helpful"
United States
Carlos
The price is HK$1,436
HK$1,717 total
includes taxes & fees
19 Dec - 20 Dec
Orazio Palace Hotel
Premium bedding, minibar, in-room safe, desk
NH Collection Roma Giustiniano

NH Collection Roma Giustiniano

NH Collection Roma Giustiniano
4.0 star property
Rome City Centre
8.8 out of 10, Excellent, (1001)
"Great location. Good shopping nearby. Walk to Vatican museums. Friendly staff. Room was spacious and clean."
United States
Leanora A
The price is HK$1,454
HK$1,736 total
includes taxes & fees
8 Jan - 9 Jan 2026
NH Collection Roma Giustiniano
Rooftop terrace
Hotel Isa

Hotel Isa

Hotel Isa
4.0 star property
Rome City Centre
9.4 out of 10, Exceptional, (1005)
"Just a wonderful place to stay, great views, clean rooms and wonderful staff. Breakfast was always a treat and the location is great for walking everywhere. "
Canada
William Darren
Hotel Isa
2 restaurants, pizza
Mama Shelter Roma

Mama Shelter Roma

Mama Shelter Roma
4.0 star property
Vatican
9.0 out of 10, Wonderful, (898)
"Very nice bedding and comfortable bed. Room always clean and staff are very friendly."
United States
Irma
The price is HK$1,029
HK$1,372 total
includes taxes & fees
9 Jan - 10 Jan 2026
Mama Shelter Roma
Lobby lounge
AC Hotel by Marriott Clodio Roma

AC Hotel by Marriott Clodio Roma

AC Hotel by Marriott Clodio Roma
4.0 star property
Vatican
9.0 out of 10, Wonderful, (52)
"Spotless clean ,renovated ,very polite staff... I was able to take the bus and be by the vatican and all the main activities in a few minutes... "
United States
zoila
The price is HK$1,263
HK$1,526 total
includes taxes & fees
22 Dec - 23 Dec
AC Hotel by Marriott Clodio Roma
Bar (on property)
The Spring House Hotel Rome Vatican, Tapestry Collection Hilton

The Spring House Hotel Rome Vatican, Tapestry Collection Hilton

The Spring House Hotel Rome Vatican, Tapestry Collection Hilton
4.0 star property
Rome City Centre
9.2 out of 10, Wonderful, (1001)
"The buffet breakfast and sauna were great!"
United States
Kelvin S
The price is HK$1,201
HK$1,458 total
includes taxes & fees
8 Jan - 9 Jan 2026
The Spring House Hotel Rome Vatican, Tapestry Collection Hilton
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

Top Vatican Hotel Reviews

San Pietro Boutique Rooms

San Pietro Boutique Rooms

10/10 Excellent
"Great place to stay in Rome. Quiet and less crowded. "
Tanya 3-night trip
Posted 5 days ago
San Pietro Boutique Rooms

Explore a world of travel with Expedia

Frequently asked questions

Are you searching for a great accommodation for your luxury getaway to Vatican?
Known for its architecture and monuments, Vatican also has some interesting things to see and do including Vatican Museums and St. Peter's Basilica, so you may want to take in the local sights during your visit.
What's the best luxury hotel in Vatican?
Villa Agrippina Gran Meliá - The Leading Hotels of the World is a luxury hotel with 4 restaurants and a full-service spa, and it's a popular choice for Expedia travellers looking for an elegant place to stay. The First Musica - Preferred Hotels & Resorts and Lunaria Suites Rome are other upscale choices for your trip.
What's there to see and do in Vatican?
Enjoy all that Vatican has to offer and visit Vatican Museums, St. Peter's Basilica and Apostolic Palace. If you have some spare time during your trip, you might want to check out Sistine Chapel and Vatican Grottoes.
How can I get around Vatican?
It's easier to get around town in style when you know your options. You can take advantage of metro transport at Ottaviano - San Pietro - Musei Vaticani Station, Risorgimento/S. Pietro Tram Stop and Milizie-Angelico Tram Stop.