Photo by Bill Dillard

Southeast Missouri 3 Stars Hotels

Start date: Check-in selected.
To Date
End date: Check-out

  • Change your mind

    Book hotels with free cancellation

  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in

  • Be picky

    Search almost a million properties worldwide

Check availability on Southeast Missouri 3 Star Hotels

Tonight
27 Dec - 28 Dec
Tomorrow
28 Dec - 29 Dec
Next weekend
2 Jan - 4 Jan
In two weeks
9 Jan - 11 Jan

Our top choices for Southeast Missouri 3-star hotels

Lobby
Drury Plaza Hotel Cape Girardeau Conference Center

Drury Plaza Hotel Cape Girardeau Conference Center

Drury Plaza Hotel Cape Girardeau Conference Center
3.0 star property
Cape Girardeau
9.6 out of 10, Exceptional, (1003)
"Great place and staff, very accommodating!"
United States
Megan
The price is HK$699
HK$789 total
includes taxes & fees
1 Jan - 2 Jan 2026
Drury Plaza Hotel Cape Girardeau Conference Center
Breakfast, lunch, dinner served; Italian cuisine
Holiday Inn Poplar Bluff by IHG

Holiday Inn Poplar Bluff by IHG

Holiday Inn Poplar Bluff by IHG
3.0 star property
Poplar Bluff
8.8 out of 10, Excellent, (707)
"Amazing place"
United States
Mladen
The price is HK$816
HK$922 total
includes taxes & fees
2 Jan - 3 Jan 2026
Holiday Inn Poplar Bluff by IHG
Property amenity
La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau

La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau

La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau
3.0 star property
Jackson
9.0 out of 10, Wonderful, (677)
"Great place "
United States
GUY
The price is HK$654
HK$708 total
includes taxes & fees
7 Jan - 8 Jan 2026
La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau
Property amenity
Drury Inn & Suites Sikeston, MO

Drury Inn & Suites Sikeston, MO

Drury Inn & Suites Sikeston, MO
3.0 star property
Sikeston
9.4 out of 10, Exceptional, (1000)
"This our favorite place to stop for a good night sleep. "
United States
Eileen
The price is HK$699
HK$804 total
includes taxes & fees
5 Jan - 6 Jan 2026
Drury Inn & Suites Sikeston, MO
Lobby
Drury Inn & Suites Poplar Bluff

Drury Inn & Suites Poplar Bluff

Drury Inn & Suites Poplar Bluff
3.0 star property
Poplar Bluff
9.2 out of 10, Wonderful, (968)
"Nice room helpful staff. "
United States
Deborah
The price is HK$816
HK$922 total
includes taxes & fees
2 Jan - 3 Jan 2026
Drury Inn & Suites Poplar Bluff
Lobby
Courtyard by Marriott Cape Girardeau Downtown

Courtyard by Marriott Cape Girardeau Downtown

Courtyard by Marriott Cape Girardeau Downtown
3.0 star property
Cape Girardeau
9.6 out of 10, Exceptional, (468)
"The staff was very helpful and friendly. The rooms were modern and clean. The downtown location was perfect for us. "
United States
Deborah
The price is HK$971
HK$1,101 total
includes taxes & fees
11 Jan - 12 Jan 2026
Courtyard by Marriott Cape Girardeau Downtown
Business centre
Drury Inn & Suites Cape Girardeau

Drury Inn & Suites Cape Girardeau

Drury Inn & Suites Cape Girardeau
3.0 star property
Cape Girardeau
9.4 out of 10, Exceptional, (1000)
"Very friendly staff and great breakfast"
United States
Ray
The price is HK$699
HK$789 total
includes taxes & fees
1 Jan - 2 Jan 2026
Drury Inn & Suites Cape Girardeau
Lobby
Drury Inn & Suites Hayti Caruthersville

Drury Inn & Suites Hayti Caruthersville

Drury Inn & Suites Hayti Caruthersville
3.0 star property
Hayti
9.4 out of 10, Exceptional, (1000)
"Staff is very friendly. Breakfast was good. "
United States
Samantha
The price is HK$730
HK$832 total
includes taxes & fees
10 Jan - 11 Jan 2026
Drury Inn & Suites Hayti Caruthersville
Lobby
La Quinta Inn & Suites by Wyndham Festus - St. Louis South

La Quinta Inn & Suites by Wyndham Festus - St. Louis South

La Quinta Inn & Suites by Wyndham Festus - St. Louis South
3.0 star property
Festus
8.0 out of 10, Very good, (893)
"Breakfast was great! Location right off interstate was perfect. The property is a little old."
United States
Mindy
The price is HK$720
HK$823 total
includes taxes & fees
4 Jan - 5 Jan 2026
La Quinta Inn & Suites by Wyndham Festus - St. Louis South
Lobby
Drury Inn & Suites Jackson MO

Drury Inn & Suites Jackson MO

Drury Inn & Suites Jackson MO
3.0 star property
Jackson
9.6 out of 10, Exceptional, (1003)
"Breakfast was great- staff was welcoming. Will stay there again."
United States
Laura
The price is HK$645
HK$682 total
includes taxes & fees
1 Jan - 2 Jan 2026
Drury Inn & Suites Jackson MO
Meeting facility
Baymont by Wyndham Festus

Baymont by Wyndham Festus

Baymont by Wyndham Festus
3.0 star property
Festus
6.8 out of 10, (924)
"Room was clean and comfortable for an overnight stay"
United States
Jack
The price is HK$629
HK$720 total
includes taxes & fees
30 Dec - 31 Dec
Baymont by Wyndham Festus
Children’s play area – outdoor
Honeysuckle Inn - Mountain View

Honeysuckle Inn - Mountain View

Honeysuckle Inn - Mountain View
3.0 star property
Mountain View
8.6 out of 10, Excellent, (334)
"Staff was very friendly."
United States
Joyce
The price is HK$699
HK$758 total
includes taxes & fees
25 Jan - 26 Jan 2026
Honeysuckle Inn - Mountain View
BBQ/picnic Area
Current River Inn

Current River Inn

Current River Inn
3.0 star property
Van Buren
8.2 out of 10, Very good, (165)
"The mattresses were fabulous. Clean rooms and friendly staff. We will stay here again. The antique store and restaurants are walking distance. Nice family friendly establishment!"
United States
Thad
The price is HK$640
HK$693 total
includes taxes & fees
30 Dec - 31 Dec
Current River Inn
Bar (on property)
TownePlace Suites by Marriott Sikeston

TownePlace Suites by Marriott Sikeston

TownePlace Suites by Marriott Sikeston
3.0 star property
Sikeston
9.2 out of 10, Wonderful, (9)
"Great hotel! Very clean, quiet, plenty of amenities, pool was clean, breakfast in the morning was good with lots of options. I would definitely stay here again. "
United States
Scott
The price is HK$918
HK$1,039 total
includes taxes & fees
4 Jan - 5 Jan 2026
TownePlace Suites by Marriott Sikeston
Premium bedding, individually decorated, individually furnished
EC Reed's Mercantile and Hotel

EC Reed's Mercantile and Hotel

EC Reed's Mercantile and Hotel
3.0 star property
Marble Hill
9.6 out of 10, Exceptional, (84)
"Cute room, great food, fun soda fountain and friendly owners! Will return! "
United States
Leslie
EC Reed's Mercantile and Hotel
Shared kitchen
Arcadia Academy

Arcadia Academy

Arcadia Academy
3.0 star property
Arcadia
9.8 out of 10, Exceptional, (11)
"Love the charm of the room with the hard wood floors, architecture, friendly staff and great food"
United States
Joann
The price is HK$1,058
HK$1,148 total
includes taxes & fees
1 Jan - 2 Jan 2026
Arcadia Academy
Exterior
Walk to Dtwn: Ironton Home in Historic District

Walk to Dtwn: Ironton Home in Historic District

Walk to Dtwn: Ironton Home in Historic District
3.0 star property
Ironton
10.0 out of 10, Exceptional, (1)
"Clean and comfortable "
United States
Dustin
Walk to Dtwn: Ironton Home in Historic District
Exterior detail
Fox Pen Cabins Cabin #2 Not friendly for street bikes… Pet-Friendly

Fox Pen Cabins Cabin #2 Not friendly for street bikes… Pet-Friendly

Fox Pen Cabins Cabin #2 Not friendly for street bikes… Pet-Friendly
3.0 star property
Eminence
9.2 out of 10, Wonderful, (10)
"Great little cabin, roads to cabin not the best but worth it!"
United States
Pam
Fox Pen Cabins Cabin #2 Not friendly for street bikes… Pet-Friendly
Full-sized fridge, microwave, oven, stovetop
Johnson's Shut-ins State Park

Johnson's Shut-ins State Park

Johnson's Shut-ins State Park
3.0 star property
Middle Brook
10.0 out of 10, Exceptional, (1)
"These newer cabins are clean and have everything you need. Highly recommend! "
United States
Shelly
The price is HK$1,958
HK$2,070 total
includes taxes & fees
3 Jan - 4 Jan 2026
Johnson's Shut-ins State Park
Interior
Cottage w/ Yard, Walk to Historic Attractions

Cottage w/ Yard, Walk to Historic Attractions

Cottage w/ Yard, Walk to Historic Attractions
3.0 star property
Ste Genevieve
10.0 out of 10, Exceptional, (1)
"The little blue cottage was very comfortable, clean and close to everything downtown. We parked the car and walked everywhere. It was on a quiet street. The bed was comfy, clean kitchen. We liked the little back yard, for relaxing. "
United States
Terri
Cottage w/ Yard, Walk to Historic Attractions
Save an average of 15% on thousands of hotels when you're signed in
Sign in
Sign up, it's free

Explore similar 4-star hotels

Many 4-star hotels have the same amenities as 3-star hotels. See all 4-star hotels in Southeast Missouri.
The Riverview

The Riverview

777 Main St Cape Girardeau MO
The price is HK$711 per night from 29 Dec to 30 Dec
HK$711
HK$803 total
29 Dec - 30 Dec
includes taxes & fees
9.4/10 Exceptional! (475 reviews)
Still don't see what you're looking for?
See all properties in Southeast Missouri.
You can also use these popular filters to refine your search.
PoolSpaHot tubBreakfast includedWaterpark
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Learn more about Southeast Missouri

Discover the family-friendly area of Southeast Missouri—wineries, a scenic riverfront and sights from K Bridge Recreation Area to Lake Wappapello State Park.

See all hotels in Southeast Missouri
Mini Takes the States 2014 Road Rally Memphis to St.Louis Leg: Moark Regional Railroad Museum HOURS: Saturdays 1 p.m. - 4 p.m. It was not open when I stopped by but there are a few rail cars outside. Poplar has a train rich history. This was a cool little town to stop in and take pictures. Lot's of wall murals for some reason, and some very cool architecture. Worth the stop and be sure and enjoy a lunch at Hayden's Drive-In ! #MTTS2014 #minitakesthestates #go11 #train
Photo by Bill Dillard
Open Photo by Bill Dillard

Top Southeast Missouri Hotel Reviews

Drury Inn & Suites Sikeston, MO

Drury Inn & Suites Sikeston, MO

10/10 Excellent
"This our favorite place to stop for a good night sleep. "
Eileen 1-night trip
Posted 5 days ago
Drury Inn & Suites Sikeston, MO

Frequently asked questions

What are the best 3-star hotels in Southeast Missouri?
If you're staying in Cape Girardeau for your Southeast Missouri holiday, you'll find some cosy 3-star hotels. Many Expedia travellers book Courtyard by Marriott Cape Girardeau Downtown. Around 0.64 kilometres west of the downtown area, it features a terrace and a cafe. Another highly rated escape is Drury Plaza Hotel Cape Girardeau Conference Centre. Book a room here and enjoy access to a swimming pool and high-speed internet services, and be approximately 8 kilometres west of the centre.
How much does it cost to stay in a 3-star hotel in Southeast Missouri?
Use Expedia's sort and search filters to land an affordable 3-star hotel for your Southeast Missouri break. Just set your maximum rate with our pricing tool. You can also pick your amenities, preferred neighbourhood and lots more.

  • Search for the lowest price per night right now from HK$803

What is the difference between a 4-star and 3-star hotel in Southeast Missouri?
Relaxation is effortless in 3-star hotels in Southeast Missouri. In addition to pleasant surroundings, these more affordable stays come with a wealth of amenities like WiFi, coffee maker and on-site gym. A 4-star hotel offers a more sophisticated experience with upscale features such as an on-site spa centre, outdoor or indoor pool and more spacious rooms. Regardless of your desired hotel category or budget, we have the ideal match for you.

Explore a world of travel with Expedia