Lodging Image

Southeast Missouri 3 Stars Hotels

  • Change your mind

    Book hotels with free cancellation

  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in

  • Be picky

    Search almost a million properties worldwide

Check availability on Southeast Missouri 3 Star Hotels

Tonight
26 Sept - 27 Sept
Tomorrow
27 Sept - 28 Sept
Next weekend
2 Oct - 4 Oct
In two weeks
9 Oct - 11 Oct

Our top choices for Southeast Missouri 3-star hotels

A spacious lobby with a circular seating area, a stone fireplace, and modern lighting fixtures.
A spacious corridor with a high ceiling, recessed lighting, and a series of posters on the walls.
An indoor swimming pool with clear blue water, surrounded by beige walls and large windows.
A spacious lobby with a curved seating area, a reception desk, and a large window providing natural light.

1. Drury Plaza Hotel Cape Girardeau Conference Center

Drury Plaza Hotel Cape Girardeau Conference Center
Cape Girardeau
United States
Sandra
HK$784
HK$885 total
includes taxes & fees
1 Oct - 2 Oct
Drury Plaza Hotel Cape Girardeau Conference Center
An indoor swimming pool with a 3 FT depth marker, a metal ladder, and a tiled floor.
An outdoor seating area with sofas and planters, surrounded by a building with large windows and a brick wall.
A spacious lobby with a polished floor, seating areas, and modern lighting fixtures.
A spacious dining area with high tables and chairs, a bar counter, and large windows providing natural light.

2. Drury Inn & Suites Sikeston, MO

Drury Inn & Suites Sikeston, MO
Sikeston
United States
Scott
HK$737
HK$848 total
includes taxes & fees
1 Oct - 2 Oct
Drury Inn & Suites Sikeston, MO
A hotel entrance with a large sign reading "LAQUINTA" and a sun graphic.
A reception desk with a large mural of a bridge, wooden reception area, and a potted plant.
A breakfast bar with a coffee machine, waffle maker, toaster, and various food items.
An outdoor patio with tables and chairs, a stone wall, and large windows.

3. La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau

La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau
Jackson
United States
Elaine
HK$660
HK$714 total
includes taxes & fees
5 Oct - 6 Oct
La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau
A hotel room with a sofa, a small table, a chair, a desk, two lamps, a window with curtains, and a framed picture on the wall.
A Holiday Inn hotel with a main entrance, a Holiday Inn Express, and a Carvel restaurant.
A hotel room with a desk, chair, and a small seating area. It includes a microwave, coffee maker, and a refrigerator.
A hotel room with two beds, a bedside lamp, a bench, a mirror, and a door leading to another room.

4. Holiday Inn Poplar Bluff by IHG

Holiday Inn Poplar Bluff by IHG
Poplar Bluff
United States
Nathan
HK$651
HK$736 total
includes taxes & fees
25 Oct - 26 Oct
Holiday Inn Poplar Bluff by IHG
A spacious lobby with a modern design, featuring a seating area with patterned armchairs and a round table, a large window, and a fireplace with decorative wall art.
An indoor swimming pool with multiple lanes, surrounded by seating areas and tables.
A hotel room with a brick wall, two beds, a desk with a TV, and a patterned carpet.
A gym with treadmills, elliptical machines, and a mirrored wall.

5. Drury Inn & Suites Hayti Caruthersville

Drury Inn & Suites Hayti Caruthersville
Hayti
United States
Philip
HK$800
HK$912 total
includes taxes & fees
11 Oct - 12 Oct
Drury Inn & Suites Hayti Caruthersville
A modern living room with a sofa, armchairs, a coffee table, and a TV mounted on the wall.
A modern living room with a sofa, a coffee table, and a dining area with chairs and a table.
A Fairfield by Marriott hotel with a modern design, featuring a stone facade, multiple floors, and a well-lit entrance.
An indoor swimming pool with lounge chairs and tables, large windows, and a view of the outside.

6. Fairfield Inn & Suites by Marriott Cape Girardeau

Fairfield Inn & Suites by Marriott Cape Girardeau
Cape Girardeau
United States
Carlos
HK$793
HK$895 total
includes taxes & fees
11 Oct - 12 Oct
Fairfield Inn & Suites by Marriott Cape Girardeau
A spacious lobby with a reception desk, seating area, and large windows.
A spacious lobby with a high ceiling, a mezzanine level, and a seating area with a sofa and chairs.
An indoor swimming pool with a clear view of the outside through large windows.
A spacious conference room with brick walls, multiple tables and chairs, a large window, and a mounted TV.

7. Drury Inn & Suites Poplar Bluff

Drury Inn & Suites Poplar Bluff
Poplar Bluff
United States
Dean
HK$737
HK$833 total
includes taxes & fees
18 Oct - 19 Oct
Drury Inn & Suites Poplar Bluff
A spacious lobby with a large sectional sofa, multiple armchairs, and a coffee table. There is a TV mounted on the wall and a large window providing a view of the outdoors.
A hotel room with two beds, a brick wall, and a wooden headboard.
An indoor swimming pool with a wooden ceiling, lounge chairs, and a lifeguard chair.
A restaurant with a brick wall, a flat-screen TV, and a bar area.

8. Drury Inn & Suites Jackson MO

Drury Inn & Suites Jackson MO
Jackson
United States
Thomas
HK$659
HK$696 total
includes taxes & fees
11 Oct - 12 Oct
Drury Inn & Suites Jackson MO
A spacious lobby with marble flooring, elegant seating, and a grand staircase.
A Courtyard by Marriott hotel with a modern brick facade, large windows, and a covered entrance area.
A lobby with seating areas, a reception desk, and a bar.
A modern hotel lobby with a framed advertisement for breakfast at the new Bistro, a seating area with sofas and a coffee table, and a decorative mirror reflecting the space.

9. Courtyard by Marriott Cape Girardeau Downtown

Courtyard by Marriott Cape Girardeau Downtown
Cape Girardeau
United States
Kristin
HK$981
HK$1,112 total
includes taxes & fees
11 Oct - 12 Oct
Courtyard by Marriott Cape Girardeau Downtown
A hotel room with two beds, a desk, a chair, a TV, and a large window with a view.
A modern bathroom with a glass shower enclosure, a vanity with a mirror, and a towel rack.
A modern hotel room with a large bed, a desk, a TV, and a balcony with a view.
A modern hotel room with a kitchen area, a dining space, and a living area with a view.

10. Century Casino & Hotel Caruthersville

Century Casino & Hotel Caruthersville
Caruthersville
United States
Philip
HK$953
HK$1,084 total
includes taxes & fees
28 Sept - 29 Sept
Century Casino & Hotel Caruthersville
A modern lounge area with a stone fireplace, blue seating, a round coffee table, and a large window offering a view.
A corner market with a refrigerated display case and a pantry area.
A reception area with a wooden counter, a coffee machine, and a display of pastries.
An outdoor patio with a table and chairs, a large umbrella, and a glass door leading to an interior space.

11. Fairfield Inn & Suites by Marriott Poplar Bluff

Fairfield Inn & Suites by Marriott Poplar Bluff
Poplar Bluff
United States
Vicki
HK$793
HK$896 total
includes taxes & fees
4 Oct - 5 Oct
Fairfield Inn & Suites by Marriott Poplar Bluff
A modern lobby with seating areas, a patterned carpet, and a cityscape mural on the wall.
A hotel room with a large bed, a bedside table with a lamp, a vanity with a mirror, and a wall with framed pictures.
A modern hotel with a prominent 'La Quinta' sign, large windows, and a well-lit entrance.
A swimming pool with lounge chairs and a view of the night sky.

12. La Quinta Inn & Suites by Wyndham Festus - St. Louis South

La Quinta Inn & Suites by Wyndham Festus - St. Louis South
Festus
United States
Lisa-Marie
HK$660
HK$755 total
includes taxes & fees
30 Sept - 1 Oct
La Quinta Inn & Suites by Wyndham Festus - St. Louis South
A hotel room with a large bed, two bedside lamps, a chair, and a wooden headboard.
A plate of mixed greens salad with cherry tomatoes and croutons, a bowl of baked pasta, and a glass of red wine on a wooden table.
A breakfast setting with waffles, scrambled eggs, toast, a glass of orange juice, and a white mug on a table with a green placemat.
A hotel room with a large bed, two bedside tables, a desk with a chair, and two lamps.

13. Drury Inn & Suites Cape Girardeau

Drury Inn & Suites Cape Girardeau
Cape Girardeau
United States
Teresa
HK$714
HK$805 total
includes taxes & fees
1 Oct - 2 Oct
Drury Inn & Suites Cape Girardeau
A conference room with round tables and chairs, a patterned carpet, and a chandelier.
A restaurant with multiple tables and chairs, a counter with a coffee machine, and framed pictures on the walls.
A gym with exercise equipment including a bench, a treadmill, and weight machines.
A hotel room with a large bed, a desk, a chair, a TV mounted on the wall, and a window with curtains.

14. Baymont by Wyndham Festus

Baymont by Wyndham Festus
Festus
United States
Linda
HK$522
HK$597 total
includes taxes & fees
25 Oct - 26 Oct
Baymont by Wyndham Festus
A red wooden mill with a small bridge over a flowing river, surrounded by lush greenery.
A dining area with a round table and chairs, large windows with curtains, and a whiteboard on the wall.
A playground with a slide, climbing structures, and a small shelter.
A row of yellow buildings with white railings and a covered front porch.

15. Honeysuckle Inn - Mountain View

Honeysuckle Inn - Mountain View
Mountain View
United States
Joanne
HK$776
HK$842 total
includes taxes & fees
21 Oct - 22 Oct
Honeysuckle Inn - Mountain View
An outdoor seating area with a circular fire pit surrounded by chairs, a covered patio, and a building with large windows in the background.
A modern indoor swimming pool with clear glass walls, a tiled deck, and multiple lounge chairs.
A modern hotel building with a sign reading "TOWNPLACE SUITES BY MARRIOTT" and "Fairfield BY MARRIOTT".
A modern lobby with a green sofa, two armchairs, a wooden coffee table, and a patterned rug.

16. Fairfield Inn & Suites by Marriott Sikeston

Fairfield Inn & Suites by Marriott Sikeston
Sikeston
United States
Allen
HK$792
HK$897 total
includes taxes & fees
4 Oct - 5 Oct
Fairfield Inn & Suites by Marriott Sikeston
A bedroom with a bed, a desk, and a chair. There is a window with curtains, a radiator, and a wall-mounted shelf with a towel.
A motel with a parking lot, a covered picnic area, and a row of rooms with individual entrances.
A swimming pool with a green deck and white lounge chairs. There are buildings in the background with a 'No Driving' sign.
A playground with slides and swings, a mailbox, and a caution sign.

17. Current River Inn

Current River Inn
Van Buren
United States
Misty
HK$854
HK$924 total
includes taxes & fees
27 Sept - 28 Sept
Current River Inn
A modern hotel with a sign reading "Towneplace Suites by Marriott Fairfield." It features a flat roof, large windows, and a well-lit entrance.
An outdoor bar area with a modern design, featuring a counter, bar stools, and a seating area with chairs.
A modern hotel room with a large window, a gray sofa, a small round table, a white chair, and a bed.

18. TownePlace Suites by Marriott Sikeston

TownePlace Suites by Marriott Sikeston
Sikeston
United States
Stacy
HK$784
HK$888 total
includes taxes & fees
4 Oct - 5 Oct
TownePlace Suites by Marriott Sikeston
A living room with a blue wall, a fireplace, a sofa, and a chair.
A sign for EC REED'S MERCANTILE & HOTEL with a geometric design.
A brick building with a sign reading "Mercantile & Hotel".
A bar area with stools and a counter where a bartender is serving drinks.

19. EC Reed's Mercantile and Hotel

EC Reed's Mercantile and Hotel
Marble Hill
United States
JANEEN
HK$825
HK$898 total
includes taxes & fees
18 Oct - 19 Oct
EC Reed's Mercantile and Hotel
A bedroom with a bed, bedside table, and wall-mounted light fixtures.
A wooden cabin with a balcony, a small attached room, and a clear sky in the background.
A cozy living room with a sofa, armchairs, a coffee table, and a lamp. There are wall art pieces and a mirror.
A cabin with a porch and steps leading to a deck, situated near a body of water.

20. Johnson's Shut-ins State Park

Johnson's Shut-ins State Park
Middle Brook
United States
Aleksandr
Johnson's Shut-ins State Park
Save an average of 15% on thousands of hotels when you're signed in

Explore similar 4-star hotels

Many 4-star hotels have the same amenities as 3-star hotels. See all 4-star hotels in Southeast Missouri.
The Riverview

The Riverview

777 Main St Cape Girardeau MO
HK$896
HK$1,011 total
6 Oct - 7 Oct
includes taxes & fees
9.4/10 Exceptional! (667 reviews)
The Riverview
Urban Lofts

Urban Lofts

104 North Jackson Street Perryville MO
Get ratesUrban Lofts
Still don't see what you're looking for?
See all properties in Southeast Missouri.
You can also use these popular filters to refine your search.
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Learn more about Southeast Missouri

Discover the family-friendly area of Southeast Missouri—wineries, a scenic riverfront and sights from K Bridge Recreation Area to Lake Wappapello State Park.

See all hotels in Southeast Missouri
A historical marker sign for the Frisco Depot, detailing its construction in 1928, architectural style, and historical significance.
Photo by Bill Dillard

Top Southeast Missouri Hotel Reviews

Drury Inn & Suites Hayti Caruthersville

Drury Inn & Suites Hayti Caruthersville

10/10 Excellent
"Food and drinks were very good."
Philip 1-night trip
Posted 22 hours ago
Drury Inn & Suites Hayti Caruthersville
Drury Inn & Suites Sikeston, MO

Drury Inn & Suites Sikeston, MO

10/10 Excellent
"Clean room and perfect stay. We have come to consistently appreciate Drury brand for a quality stay. We would definitely recommend this location for clean comfortable accommodations."
Hiram 1-night trip
Posted 3 days ago
Drury Inn & Suites Sikeston, MO
Drury Inn & Suites Poplar Bluff

Drury Inn & Suites Poplar Bluff

10/10 Excellent
"Clean room, staff"
Lavonne 2-night trip
Posted 4 days ago
Drury Inn & Suites Poplar Bluff

Frequently asked questions

What are the best 3-star hotels in Southeast Missouri?
If you're staying in Cape Girardeau for your Southeast Missouri holiday, you'll find some cosy 3-star hotels. Many Expedia travellers book Courtyard by Marriott Cape Girardeau Downtown. Around 0.64 kilometres west of the downtown area, it features a terrace and a cafe. Another highly rated escape is Drury Plaza Hotel Cape Girardeau Conference Centre. Book a room here and enjoy access to a swimming pool and high-speed internet services, and be approximately 8 kilometres west of the centre.
How much does it cost to stay in a 3-star hotel in Southeast Missouri?
Use Expedia's sort and search filters to land an affordable 3-star hotel for your Southeast Missouri break. Just set your maximum rate with our pricing tool. You can also pick your amenities, preferred neighbourhood and lots more.
  • Search for the lowest price per night right now from HK$1,011
What is the difference between a 4-star and 3-star hotel in Southeast Missouri?
Relaxation is effortless in 3-star hotels in Southeast Missouri. In addition to pleasant surroundings, these more affordable stays come with a wealth of amenities like WiFi, coffee maker and on-site gym. A 4-star hotel offers a more sophisticated experience with upscale features such as an on-site spa centre, outdoor or indoor pool and more spacious rooms. Regardless of your desired hotel category or budget, we have the ideal match for you.

Explore a world of travel with Expedia