A coastal cityscape with high-rise buildings, a marina, and a clear blue sky.

Panama City 4 Stars Hotels

  • Change your mind

    Book hotels with free cancellation

  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in

  • Be picky

    Search almost a million properties worldwide

Check availability on Panama City 4 Star Hotels

Tonight
24 Sept - 25 Sept
Tomorrow
25 Sept - 26 Sept
This weekend
25 Sept - 27 Sept
Next weekend
2 Oct - 4 Oct

Our top choices for Panama City 4-star hotels

A spacious lobby with a high ceiling, modern lighting fixtures, and a glass entrance leading to a lower level.
A modern restaurant with checkered flooring, wooden chairs, and large windows offering a view of greenery.
A modern dining area with a wooden table and chairs, a built-in bookshelf, and a decorative hanging light fixture.
A swimming pool with a clear water surface, surrounded by a covered area with lounge chairs and a bar area.

1. Crowne Plaza Panama Airport by IHG

Crowne Plaza Panama Airport by IHG
Tocumen Airport
United States
Xenia
HK$1,059
HK$1,217 total
includes taxes & fees
1 Oct - 2 Oct
Crowne Plaza Panama Airport by IHG
A multi-story building with balconies, arched windows, and decorative railings.
A building with a balcony and a street view.
A spacious lobby with a wooden staircase, multiple seating areas, and a reception desk.
A multi-level atrium with wooden staircases, seating areas, and a decorative ceiling.

2. Central Hotel Panama Casco Viejo

Central Hotel Panama Casco Viejo
Casco Viejo
United States
Olga
HK$1,492
HK$1,641 total
includes taxes & fees
27 Sept - 28 Sept
Central Hotel Panama Casco Viejo
A high-rise building with a modern architectural design, featuring a grid of windows and balconies.
A rooftop lounge with modern seating and a panoramic city view.
An escalator in a hotel lobby with a patterned wall and framed artwork.
A rooftop pool area with purple lounge chairs and a city skyline in the background.

3. Megapolis Hotel Panamá

Megapolis Hotel Panamá
San Francisco
United States
Devika
HK$1,260
HK$1,386 total
includes taxes & fees
27 Sept - 28 Sept
Megapolis Hotel Panamá
A hotel room with a large bed, a smaller bed, a sofa, a TV mounted on the wall, and a dining area with a table and chairs.
A reception area with marble reception desks and a sign indicating the reception desk.
A buffet area with a variety of dishes, a long counter with food, and a seating area with tables and chairs.

4. Hotel El Panama by Faranda Grand, a member of Radisson Individuals

Hotel El Panama by Faranda Grand, a member of Radisson Individuals
Bella Vista
United States
abbigale
HK$800
HK$880 total
includes taxes & fees
15 Oct - 16 Oct
Hotel El Panama by Faranda Grand, a member of Radisson Individuals
A balcony with wicker chairs and a view of the cityscape.
A hotel room with a large bed, a desk with a lamp, a chair, and a view of a cityscape through a window.
A multi-story hotel with a modern facade, large windows, and a prominent entrance with a covered area.
A reception area with a marble wall, a 'Free Wireless Internet' sign, and a floral arrangement.

5. Ramada Plaza by Wyndham Panama Punta Pacifica

Ramada Plaza by Wyndham Panama Punta Pacifica
San Francisco
United States
Maria
HK$775
HK$852 total
includes taxes & fees
26 Sept - 27 Sept
Ramada Plaza by Wyndham Panama Punta Pacifica
A resort with a large swimming pool, thatched-roof structures, and palm trees.
A well-maintained garden with a pathway leading to a gazebo, surrounded by palm trees and a view of the sea.
A hotel room with a large bed, a chair, a desk, and a view of the ocean.
A resort with a pool, palm trees, and a building with a red roof.

6. Dreams Playa Bonita Panama - All Inclusive

Dreams Playa Bonita Panama - All Inclusive
Veracruz
United States
Joanna
HK$2,183
HK$2,183 total
includes taxes & fees
3 Oct - 4 Oct
Dreams Playa Bonita Panama - All Inclusive
An outdoor patio with wooden tables and beige umbrellas, surrounded by lush greenery and palm trees.
A playground with multiple slides and climbing structures.
A hotel room with two beds, a nightstand with a phone, and a wall-mounted light fixture.
A swimming pool with a bridge, surrounded by palm trees and a building with a sloped roof.

7. Riande Aeropuerto Hotel & Casino

Riande Aeropuerto Hotel & Casino
Tocumen Airport
United States
Tanese
HK$849
HK$934 total
includes taxes & fees
27 Sept - 28 Sept
Riande Aeropuerto Hotel & Casino
A modern building with a glass facade, a curved structure, and a flat roof.
A spacious lobby with red and blue seating, a large circular wall feature, and a modern design with concrete elements.
A modern hotel room with a large bed, a TV, a desk, and a view of the city.
A rooftop lounge area with clear glass tables and chairs, a pool, and potted plants.

8. Decapolis Hotel Panama City

Decapolis Hotel Panama City
San Francisco
United States
Jorge Luis
HK$867
HK$954 total
includes taxes & fees
10 Oct - 11 Oct
Decapolis Hotel Panama City
A multi-story hotel with a Marriott sign, surrounded by high-rise buildings and a busy street with cars.
A modern cafe with wooden tables and chairs, large windows, and decorative vases on shelves.
A coastal building complex with multiple structures, a prominent tower, and a beach in the foreground.
A modern lounge area with a wooden partition, a bar with a variety of bottles, and a seating area with chairs.

9. Courtyard by Marriott Panama Multiplaza Mall

Courtyard by Marriott Panama Multiplaza Mall
San Francisco
United States
Holly
HK$925
HK$1,017 total
includes taxes & fees
10 Oct - 11 Oct
Courtyard by Marriott Panama Multiplaza Mall
A modern lobby with a glass railing, a central staircase, and a view of the cityscape through large windows.
An indoor swimming pool with lounge chairs and a modern interior design.
A modern hotel room with a large window offering a city view, a chandelier, and a cozy seating area.
A modern living area with a sofa, chairs, and a coffee table. There is a view of the city through large windows.

10. Las Americas Golden Tower Panama

Las Americas Golden Tower Panama
San Francisco
United States
Armando
HK$1,082
HK$1,191 total
includes taxes & fees
11 Oct - 12 Oct
Las Americas Golden Tower Panama
A rooftop pool area with lounge chairs and a bar, overlooking a city skyline at sunset.
A spacious lobby with high ceilings, large windows, and modern lighting fixtures.
A rooftop terrace with outdoor seating, potted plants, and a view of a hill with buildings in the distance.
A buffet setup with various dishes and utensils.

11. Marriott Panama Hotel

Marriott Panama Hotel
Panama City
United States
Richard
HK$1,325
HK$1,458 total
includes taxes & fees
10 Oct - 11 Oct
Marriott Panama Hotel
A hotel room with a large bed, bedside tables with lamps, a chair, and a large window with curtains.
A rooftop swimming pool with lounge chairs and a city skyline in the background.
A cityscape with modern high-rise buildings, including a prominent tower labeled 'TOWERBANK.'
A hotel room with a bed, bedside tables, a nightstand, a lamp, a digital clock, a bathroom with a toilet, a sink, and a mirror.

12. Studio Coliving

Studio Coliving
Bella Vista
Studio Coliving
A rooftop pool with sun loungers and a city skyline in the background.
A long, narrow hallway with a wooden floor and light-colored walls.
A spacious lobby with a blue sofa, multiple armchairs, and a coffee table.
A modern hotel room with a large bed, a desk, a chair, and a wardrobe.

13. Waymore Hotel Spa & Casino

Waymore Hotel Spa & Casino
Bella Vista
United States
Abeke
HK$559
HK$1,046 total
includes taxes & fees
25 Sept - 26 Sept
Waymore Hotel Spa & Casino
A modern hotel entrance with a prominent 'NOVOTEL' sign, large glass windows, and geometric light patterns on the facade.
A bar area with a variety of liquor bottles, a counter, and seating with tables and chairs.
A spacious lobby with large windows, a curved ceiling, and a seating area with a patterned rug.
A hotel room with a bed and a view of a cityscape through sheer curtains.

14. Novotel Panama City

Novotel Panama City
Bella Vista
United States
Philip
HK$889
HK$978 total
includes taxes & fees
4 Oct - 5 Oct
Novotel Panama City
A resort with a pool area, lounge chairs, and a view of a bridge at night.
A reception desk with three staff members, a green patterned wall, a wooden reception area, and a large plant.
A hotel room with a bed, a TV on a wooden cabinet, a nightstand with a lamp, and a view of the outdoors through a glass door.
A bar area with a counter, stools, and a seating area with tables and chairs.

15. Radisson Hotel Panama Canal

Radisson Hotel Panama Canal
Amador
United Kingdom
Samantha
HK$622
HK$684 total
includes taxes & fees
8 Oct - 9 Oct
Radisson Hotel Panama Canal
A buffet with various food items and a decorative plant.
A spacious lobby with a high ceiling, a glass railing on the upper level, and a seating area with modern furniture.
A gym with treadmills, weight machines, and a red carpet.
A spa area with a hot tub, candles, and a curved bench.

16. Sheraton Grand Panama

Sheraton Grand Panama
San Francisco
United States
Noel
HK$1,376
HK$1,514 total
includes taxes & fees
1 Oct - 2 Oct
Sheraton Grand Panama
A poolside area with covered seating and palm trees.
A modern reception area with a large window, a geometric patterned floor, and two potted plants.
A modern living room with a city view, a flat-screen TV, and a dining area with white chairs and a table.
A modern hotel lobby with a glass facade, seating area with loungers, and a wooden floor.

17. Sortis Hotel, Spa & Casino, Autograph Collection by Marriott

Sortis Hotel, Spa & Casino, Autograph Collection by Marriott
Bella Vista
United States
Charles
HK$1,561
HK$1,717 total
includes taxes & fees
28 Sept - 29 Sept
Sortis Hotel, Spa & Casino, Autograph Collection by Marriott
A spacious indoor area with high ceilings, large windows, and multiple dining tables.
A spacious lobby with a tiled floor, large windows, and potted plants.
A multi-story hotel with a central courtyard, balconies, and a view of the city skyline.
A restaurant with brick walls, arched windows, and a variety of seating arrangements including tables and chairs.

18. American Trade Hotel

American Trade Hotel
Casco Viejo
United States
RAINIERO
HK$1,593
HK$1,753 total
includes taxes & fees
1 Oct - 2 Oct
American Trade Hotel
A wooden door with a number plate, a black and white striped bag, and a lantern on the ground.
A rooftop terrace with a city skyline view, a pool, and outdoor seating.
A rooftop bar with potted plants, seating, and a view of a city skyline.
A bedroom with a large bed, a stone wall, a wooden bench, and a hanging light fixture.

19. Hotel Casa Panamá

Hotel Casa Panamá
Casco Viejo
United States
Naveera Jyoti
HK$522
HK$574 total
includes taxes & fees
17 Oct - 18 Oct
Hotel Casa Panamá
A high-rise hotel with multiple floors, a prominent "Residence Inn by Marriott" sign, and a "Panama Clinic" sign.
A modern bar area with multiple seating options and a view of the cityscape.
A hotel room with two beds, a sofa, a bench, a TV, and a view of buildings.
A modern conference room with a long table, colorful chairs, and large windows offering a city view.

20. Residence Inn by Marriott Panama City

Residence Inn by Marriott Panama City
San Francisco
United States
Cassandre
HK$1,474
HK$1,622 total
includes taxes & fees
3 Oct - 4 Oct
Residence Inn by Marriott Panama City
Save an average of 15% on thousands of hotels when you're signed in

Explore similar 5-star hotels

Many 5-star hotels have the same amenities as 4-star hotels. See all 5-star hotels in Panama City.
Hotel Riu Plaza Panama

Hotel Riu Plaza Panama

Calle 50, Urb. Marbella Panama City Panama
HK$1,080
HK$1,187 total
29 Sept - 30 Sept
includes taxes & fees
9/10 Wonderful! (5,954 reviews)
Hotel Riu Plaza Panama
Waldorf Astoria Panama

Waldorf Astoria Panama

47th St. & Uruguay Street Panama City Panama
HK$2,052
HK$2,257 total
17 Oct - 18 Oct
includes taxes & fees
9/10 Wonderful! (1,000 reviews)
Waldorf Astoria Panama
Sofitel Legend Casco Viejo, Panama City

Sofitel Legend Casco Viejo, Panama City

Calle Primera Oeste, San Felipe Panama City Panama
HK$3,106
HK$3,417 total
5 Oct - 6 Oct
includes taxes & fees
9.8/10 Exceptional! (750 reviews)
Sofitel Legend Casco Viejo, Panama City
Still don't see what you're looking for?
See all properties in Panama City.
You can also use these popular filters to refine your search.
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Learn more about Panama City

The gleaming skyscrapers of this cosmopolitan capital stand in striking contrast to the colonial charm of Casco Viejo. Watch massive ships navigate the Canal locks, then sample ceviche at the seafood market where local fishermen bring their daily catch.

See all hotels in Panama City
A city skyline with high-rise buildings, a calm waterfront, and a sunset sky.

Top Panama City Hotel Reviews

Hotel El Panama by Faranda Grand, a member of Radisson Individuals

Hotel El Panama by Faranda Grand, a member of Radisson Individuals

10/10 Excellent
"The hotel is a little outdated but you can tell the staff really tries to keep up with it. The staff is very kind, we talked to staff in"
Monica 5-night trip
Posted 8 hours ago
Hotel El Panama by Faranda Grand, a member of Radisson Individuals
Decapolis Hotel Panama City

Decapolis Hotel Panama City

10/10 Excellent
"Muy buena ubicación y aunque la propiedad es vieja, está muy bien cuidado. Excelente trato del personal, precios super accesibles en su bar restaurant. Me encanto el Karaoke."
Damaris 2-night trip
Posted 17 hours ago
Decapolis Hotel Panama City
Central Hotel Panama Casco Viejo

Central Hotel Panama Casco Viejo

10/10 Excellent
"Desayuno variado y muy bueno. El staff dispuesto ayudarle y recommend lugares para ver. Recomendado 100%"
carmin 2-night trip
Posted 1 day ago
Central Hotel Panama Casco Viejo

Frequently asked questions

What are the best 4-star hotels in Panama City?
Continental Hotel Panamá is a 4-star hotel in Panama City that's popular among Expedia customers. An art gallery and proposal/romance packages are just a couple of its amenities. Travellers also recommend Hotel El Panama by Faranda Grand, a member of Radisson Individuals. From a swimming pool to a steam room, it offers conveniences that cater to every aspect of your relaxation and entertainment.
How much does it cost to stay in a 4-star hotel in Panama City?
To lock in a 4-star hotel in Panama City that fits your budget, make use of Expedia's handy search filters. Take a look at the availability during your holiday dates and use our pricing filter to set your limit. You can also sort your results by the most affordable escape first.
  • Search for the lowest price from HK$1,187
What's the difference between 5-star and 4-star hotels in Panama City?
Offering a friendly traveller experience and upmarket décor, 4-star hotels are a fantastic option for your Panama City holiday. These types of accommodation generally feature loads of useful amenities that make it a breeze to unpack and unwind — think 24-hour room service, gyms and pools. Or enjoy even more lavishness at a 5-star hotel designed to indulge you in high-end perks and amenities. Concierge assistance, complimentary toiletries and fine dining are typically included at these swanky properties.

Explore a world of travel with Expedia