A beachside restaurant with white tables and chairs, palm trees, and a view of the sea.

Key Largo Spa Hotel

  • Change your mind

    Book hotels with free cancellation
  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in
  • Be picky

    Search almost a million properties worldwide

Check availability on Key Largo Spa Hotel

Tonight
11 Oct - 12 Oct
Tomorrow
12 Oct - 13 Oct
Next weekend
16 Oct - 18 Oct
In two weeks
23 Oct - 25 Oct

Our top choices for Key Largo hotels with a spa

1. Playa Largo Resort & Spa, Autograph Collection

Playa Largo Resort & Spa, Autograph Collection
Rock Harbor
  • Immerse in waterfront wellness at this bay resort with a full-service spa, offering daily Ayurvedic treatments and relaxing garden escapes.
HK$2,064
HK$2,755 total
includes taxes & fees
1 Nov - 2 Nov
Playa Largo Resort & Spa, Autograph Collection

2. Reefhouse Resort & Marina

Reefhouse Resort & Marina
Key Largo
  • Discover tranquil bliss at this waterfront haven with three spa rooms, private beach, and hot stone massages.
HK$1,719
HK$2,247 total
includes taxes & fees
12 Oct - 13 Oct
Reefhouse Resort & Marina

3. Baker's Cay Resort Key Largo, Curio Collection by Hilton

Baker's Cay Resort Key Largo, Curio Collection by Hilton
Key Largo
HK$2,181
HK$2,887 total
includes taxes & fees
20 Oct - 21 Oct
Baker's Cay Resort Key Largo, Curio Collection by Hilton

4. Kona Kai Resort and Gallery - Adults Only

Kona Kai Resort and Gallery - Adults Only
Rock Harbor
  • Serene spa getaway with tranquil gardens and sunset views from the oceanfront hot tub.
HK$1,528
HK$1,939 total
includes taxes & fees
12 Oct - 13 Oct
Kona Kai Resort and Gallery - Adults Only

5. Premium Floating Bungalow by Stay Ombi

Premium Floating Bungalow by Stay Ombi
Key Largo
  • Luxurious massages offered on spa-equipped houseboat with premium floating rooms and serene water access.
HK$5,564
HK$6,259 total
includes taxes & fees
12 Oct - 13 Oct
Premium Floating Bungalow by Stay Ombi

6. Cheeca Lodge & Spa

Cheeca Lodge & Spa
Matecumbe
  • Luxury spa sanctuary with 7 treatment rooms offers beachside massages and tranquil gardens for ultimate rejuvenation.
HK$1,483
HK$2,242 total
includes taxes & fees
13 Oct - 14 Oct
Cheeca Lodge & Spa

7. The Islands of Islamorada

The Islands of Islamorada
Matecumbe
  • Beachfront spa villa with two pools, massage services, and scenic water walkway offers rejuvenating Florida escape.
HK$4,096
HK$5,123 total
includes taxes & fees
13 Oct - 14 Oct
The Islands of Islamorada
View all properties

Choose what matters most at spa hotels in Key Largo

Pool
Hot tub
Breakfast included
Gym
5 stars

Top Key Largo Hotel Reviews

Amoray Dive Resort

Amoray Dive Resort

8/10 Good
"It was nice. We only stayed one night since we were on our way out of the Keys. The building we stayed in was under repair which was fine. The pool location is cramped and needs some up keep. Lovely beach area seating for the sunsets. Our room had some mold on the cathedral ceiling and the layout has weird wasted space so the bathroom should have been larger for a room that sleeps 4."
Leesa 1-night trip
Posted 1 hour ago
Amoray Dive Resort
Playa Largo Resort & Spa, Autograph Collection

Playa Largo Resort & Spa, Autograph Collection

10/10 Excellent
"This was my second time in Playa Largo of many more to come. The property is beautiful and meticulously maintained. With plenty of amenities and food options I rarely leave the property. Very friendly staff from the front desk to the pool staff, everyone is friendly and welcoming. Would definitely recommend! Best resort in the Keys!"
Nadieska 2-night trip
Posted 1 day ago
Playa Largo Resort & Spa, Autograph Collection
Reefhouse Resort & Marina

Reefhouse Resort & Marina

10/10 Excellent
"Spacious room and beautiful property."
Timothy 1-night trip
Posted 1 day ago
Reefhouse Resort & Marina

Frequently asked questions

Looking for a spa hotel in Key Largo?
Forget the stress of everyday life and book yourself a hotel with a spa. Travellers love the sunsets in Key Largo. Discover the coral reefs and seafood restaurants during your stay. Hotels with spas are the perfect way to break out of your daily routine and add a layer of luxury to your stay.
What is the best spa hotel in Key Largo?
Playa Largo Resort & Spa, Autograph Collection is a top beach spa hotel featuring 4 restaurants, 3 bars, a 24-hour fitness centre and a hair salon. Treat yourself to a facial, body scrub or Swedish massage at the on-site spa. Another popular spa hotel in Key Largo is Reefhouse Resort & Marina.
How many spa hotels will I find in Key Largo?
Among Expedia's 1296 accommodation options in Key Largo, there are 2 spa hotels.
What's there to see and do in Key Largo?
Enjoy Key Largo and visit Jimmy Johnson's Big Chill, Jacob's Aquatic Center and Bluefin Rock Harbor Marina. If you have a bit of extra time while you're in the area, you might want to check out John Pennekamp Coral Reef State Park and MarineLab Undersea Laboratory.
What is a Key Largo spa hotel?
Spa hotels in Key Largo provide lodging and have an on-site spa offering services such as facials and body treatments. Some also offer in-room treatments. Spa hotels are a must if you want to give yourself an extra treat while on holiday.

Explore a world of travel with Expedia