Springfield Lester E. Cox Medical Center South Hotels: 2026 Limited-Time Hotel Deals @Expedia

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Our top choices for Lester E. Cox Medical Center South hotels

A conference room with a granite table, cushioned chairs, a fruit bowl, framed pictures, and a flat-screen TV.

The exterior of Hampton Inn with a clear sign, a welcome sign, and a clearance height sign.

A gym with various exercise machines, a clock, and a motivational sign.

A business center with two computers, a printer, and a lamp. There are signs indicating the business center is available 24 hours and providing emergency and front desk contact information.

1. Hampton Inn Springfield-South

Galloway Village, 2 km from Lester E. Cox Medical Center South

Ashley

HK$798

HK$906 total

includes taxes & fees

25 Oct - 26 Oct

An outdoor patio area with red seating, a fire feature, and tables and chairs.

A modern living room with a sectional sofa, a coffee table, and yellow armchairs. There is a dining area with a table and chairs in the background.

A modern hotel lobby with a bar, seating area, kitchen, and a TV.

A modern hotel room with a large bed, a desk with a chair, a mirror, and a painting on the wall.

2. Homewood Suites by Hilton Springfield Medical District

Southside, 1.4 km from Lester E. Cox Medical Center South

Aaron

HK$1,112

HK$1,262 total

includes taxes & fees

31 Oct - 1 Nov

A hotel room with two beds, a desk, a chair, a TV, and a bathroom with a sink and mirror.

A multi-story hotel with a prominent "Candlewood Suites" sign, a parking lot, and a landscaped entrance area.

A modern hotel room with a sofa, armchair, and a dining area with a kitchen in the background.

A modern kitchen with a stainless steel microwave, a coffee maker, and a refrigerator.

3. Candlewood Suites Springfield-Medical District

0.9 km from Lester E. Cox Medical Center South

Richard

HK$926

HK$1,051 total

includes taxes & fees

1 Nov - 2 Nov

A spacious living area with large windows, a bar, and modern furniture.

A modern kitchen with a bar area, featuring a large TV, wooden shelves, and bar stools.

A modern hotel building with a prominent 'element by Westin' sign, multiple floors, and a covered entrance area.

An indoor swimming pool with clear blue water, surrounded by lounge chairs and a large windowed area.

4. Element by Marriott Springfield South

Meador Park, 1.5 km from Lester E. Cox Medical Center South

Nathaniel

HK$1,091

HK$1,238 total

includes taxes & fees

25 Oct - 26 Oct

An outdoor patio area with wicker furniture, a central fire pit, and large windows.

A spacious hotel lobby with high ceilings, large windows, and a central seating area with tables and chairs.

A lobby with a fireplace, large windows, and a view of the outdoors.

A hotel with a stone facade, large windows, and a clear blue sky.

5. Hilton Garden Inn Springfield, MO

Lake Springfield, 2.7 km from Lester E. Cox Medical Center South

daryl

HK$952

HK$1,091 total

includes taxes & fees

31 Oct - 1 Nov

A spacious lounge area with comfortable seating, a fireplace, and artwork on the walls.

An outdoor patio with wicker furniture, a round table, and a grill area.

A buffet setup with various food items, a clock, and a coffee machine.

A hotel room with a desk, chair, TV, fireplace, bed, and a small dining area.

6. Residence Inn by Marriott Springfield

Southside, 0.8 km from Lester E. Cox Medical Center South

Jacob

HK$927

HK$1,052 total

includes taxes & fees

19 Oct - 20 Oct

A hotel room with two beds, a desk with a computer, a TV, and a coffee maker.

A hotel reception area with a counter displaying various alcohol bottles, a menu board, and artwork on the walls.

An indoor swimming pool with a tiled floor, a pool ladder, and a glass door leading to another room.

A compact hotel room with a sofa, a small table, a TV, and a desk with a coffee machine.

7. La Quinta Inn & Suites by Wyndham Springfield South

Seminole Holland, 2.8 km from Lester E. Cox Medical Center South

Denise

HK$697

HK$805 total

includes taxes & fees

25 Oct - 26 Oct

A modern living room with a flat-screen TV, a fireplace, a sofa, and a dining area with a kitchen counter.

A kitchen area with a coffee machine, a buffet setup, and a dining table with chairs.

A spacious living area with a sofa, a ceiling fan, a staircase, and a kitchen area.

A compact kitchen with a microwave, toaster, and refrigerator.

8. MainStay Suites Springfield South - Battlefield Rd

Bradford Park, 1.7 km from Lester E. Cox Medical Center South

Arthur

HK$699

HK$794 total

includes taxes & fees

12 Oct - 13 Oct

An indoor swimming pool with a glass ceiling, surrounded by lounge chairs and a view of the outdoors.

A modern restaurant with a stone backsplash, wooden cabinets, and a herringbone floor pattern.

A modern living room with blue sofas, a stone accent wall, and a bookshelf.

A Comfort Inn hotel with a modern facade, a covered entrance, and a parking lot.

9. Comfort Inn South - Springfield

Galloway Village, 2.3 km from Lester E. Cox Medical Center South

Roger

HK$803

HK$911 total

includes taxes & fees

2 Nov - 3 Nov

A modern hotel lobby with a leather sofa, green chairs, a black coffee table, and a kitchen area with a green countertop.

A swimming pool with a lifeguard tower, surrounded by a fence and seating area.

A hotel room with two beds, a desk with a chair, a flat-screen TV, and a large window with curtains.

A hotel with a prominent sign, a covered parking area, and a well-lit entrance.

10. The Bradford Hotel, an Ascend Collection Hotel

Bradford Park, 0.5 km from Lester E. Cox Medical Center South

William

HK$733

HK$832 total

includes taxes & fees

1 Nov - 2 Nov

A hotel lobby with a reception desk, a staircase, and a seating area.

A modern hotel lobby with a sofa, armchairs, a coffee table, and a staircase.

A kitchen with a wooden table and chairs, a coffee machine, a fruit juicer, and a refrigerator.

A swimming pool with a hot tub, tiled floor, and a few lounge chairs.

11. Sleep Inn Springfield South I60 near Medical District

1.8 km from Lester E. Cox Medical Center South

Dina

HK$667

HK$757 total

includes taxes & fees

25 Oct - 26 Oct

A hotel room with a large bed, a chair, a nightstand, a lamp, and a door.

A hotel with a prominent sign for 'extended stay America' and a parking lot with several cars.

A compact kitchenette with white cabinets, a sink, a microwave, and a refrigerator.

A hotel reception area with a reception desk, a framed artwork, and an exit sign.

12. Extended Stay America Select Suites Springfield South

Southside, 0.9 km from Lester E. Cox Medical Center South

Crystal

HK$565

HK$641 total

includes taxes & fees

30 Oct - 31 Oct

A hotel room with a bed, bedside table, lamp, and a painting of a sunset.

A gym with exercise equipment, a treadmill, and a wall mural of athletes.

A lobby with a mural, seating area, and a refrigerator labeled 'NOURISH' and 'RECHARGE'.

A modern dining area with blue chairs and white tables, a flat-screen TV mounted on the wall, and a wooden cabinet with items on it.

13. Clarion Pointe Springfield Southeast

Galloway Village, 4.8 km from Lester E. Cox Medical Center South

Amanda

HK$622

HK$706 total

includes taxes & fees

29 Oct - 30 Oct

A modern hotel room with a large bed, a desk with a sink, and a view of the cityscape through large windows.

A rooftop lounge with wooden flooring, various seating options including sofas and chairs, a round table, and potted plants.

A bar area with a checkered floor, bar stools, and a long counter with a barista station.

A modern kitchen with a large island, bar stools, a window with a city view, and pendant lighting.

14. Hotel Vandivort

Downtown Springfield, 6.8 km from Lester E. Cox Medical Center South

George

HK$1,327

HK$1,514 total

includes taxes & fees

11 Oct - 12 Oct

A spacious indoor dining area with multiple tables and chairs, a kitchen area, and large windows allowing natural light.

A modern kitchen with a long counter, wooden cabinets, and a backsplash.

A spa area with a hot tub, a pool, and a seating area with tables and chairs.

A modern lobby with a reception desk, seating area, and a high ceiling with recessed lighting.

15. Drury Inn & Suites Springfield, MO

11.2 km from Lester E. Cox Medical Center South

Deanna

HK$847

HK$970 total

includes taxes & fees

25 Oct - 26 Oct

A cozy living room with a stone fireplace, comfortable seating, and a large mirror reflecting the room.

A hotel with a clear entrance, a covered waiting area, and a parking lot.

A hotel lobby with a large bar area, seating, a fireplace, and framed pictures on the walls.

A hotel room with a bed, bedside lamps, a desk with a sink, and a framed picture on the wall.

16. Hampton Inn Springfield-Southeast

Galloway Village, 4.9 km from Lester E. Cox Medical Center South

Donna Sue

HK$933

HK$1,059 total

includes taxes & fees

12 Oct - 13 Oct

A modern hotel room with a kitchenette, a flat-screen TV, a bed, and a large window.

A modern kitchen with wooden cabinets, a countertop with various kitchen items, and a wall-mounted shelf with decorative objects.

A modern hotel room with a dark grey sofa, a wooden side table, a desk with a chair, and two abstract paintings on the walls.

An outdoor patio area with a stone wall, wooden pergola, and seating arrangements including a sofa and chairs.

17. SpringHill Suites by Marriott Springfield North

Parkwood, 11.6 km from Lester E. Cox Medical Center South

Amanda

HK$895

HK$1,051 total

includes taxes & fees

25 Oct - 26 Oct

A hotel room with two beds, a wooden headboard, bedside tables with lamps, and a small nightstand.

A gym with treadmills, weight machines, and exercise mats.

A coffee station with two espresso machines, a coffee press, and various coffee cups and containers.

A Holiday Inn Express & Suites hotel with a parking lot and multiple vehicles.

18. Holiday Inn Express & Suites Springfield North by IHG

11.8 km from Lester E. Cox Medical Center South

Jerry

HK$895

HK$1,016 total

includes taxes & fees

18 Oct - 19 Oct

An outdoor patio with stone walls, round tables, chairs, and umbrellas.

An indoor swimming pool with clear glass walls, lounge chairs, and a lifeguard chair.

A modern living room with a wooden dining table, comfortable seating, a stone accent wall, and a large window.

A modern hotel room with a stone accent wall, a flat-screen TV, a fireplace, a sofa, a dining area, and a patterned carpet.

19. Fairfield Inn & Suites by Marriott Springfield North

Doling, 10.7 km from Lester E. Cox Medical Center South

Kristal

HK$822

HK$952 total

includes taxes & fees

25 Oct - 26 Oct

An outdoor patio area with a stone wall, a fire pit, and outdoor seating.

A hotel room with a desk, two beds, a sofa, a TV, and a large window.

An indoor swimming pool with a lifeguard chair, poolside chairs, and a view of the parking lot outside.

A modern hotel with a prominent "HOME 2" sign, a covered entrance, and a parking area with a handicap parking space.

20. Home2 Suites by Hilton Springfield North

Parkwood, 11.4 km from Lester E. Cox Medical Center South

Vicky

HK$1,147

HK$1,313 total

includes taxes & fees

1 Nov - 2 Nov

View all properties

Compare popular hotels close to Lester E. Cox Medical Center South

Property	Property class	Guest rating
Hampton Inn Springfield-South	9.4 Exceptional 717 reviews	View
Homewood Suites by Hilton Springfield Medical District	9.4 Exceptional 564 reviews	View
Candlewood Suites Springfield-Medical District	9.2 Wonderful 434 reviews	View
Element by Marriott Springfield South	9.2 Wonderful 155 reviews	View
Hilton Garden Inn Springfield, MO	9.0 Wonderful 878 reviews	View

Top Lester E. Cox Medical Center South Hotel Reviews

The Bradford Hotel, an Ascend Collection Hotel

10/10 Excellent

"Nice clean room"

Comfort Inn South - Springfield

8/10 Good

"Rooms were clean and refreshed. closet door latch was broke, and toilet wobbled. Notified desk at end of stay, and stated they would be handled. :-)"

Homewood Suites by Hilton Springfield Medical District

8/10 Good

"Good"

Holiday Inn Express and Suites Springfield Medical District by IHG

10/10 Excellent

"This is gonna be our go to stay in Springfield. The staff was friendly. The place was very clean. Our room was very clean. We had a standard two queen room that was huge. The bed was super comfortable. The pool area and hot tub was super clean and very nice and their breakfast was really good."

Element by Marriott Springfield South

10/10 Excellent

"Great place to stay"

Residence Inn by Marriott Springfield

10/10 Excellent

"Great! I love staying with the Marriotts. Always my first choice."

Peaceful Retreat near Medical Mile in Springfield

10/10 Excellent

"Soooo clean. Has everything you need!!! Love this property!!! Will be back"

Candlewood Suites Springfield-Medical District

10/10 Excellent

"There was some issues with smells from other unit, people use these for extended stays and must cook alot in them, so we woke up to burning smells throughout the night and early morning."

Comfortable Home Near CoxHealth & MSU - Fenced Yard

10/10 Excellent

"The house was better than described, very comfortable and everything is right there I mean right there, I was pleasantly surprised on how I was able to get ot everything in no time flat, the only thing that was a hike was the airport."

Frequently asked questions

What's the area like around Lester E. Cox Medical Center South?

Lester E. Cox Medical Center South is located in a welcoming area of Springfield that travellers like for its sporting events and opera houses. If you're looking for a convenient place to stay, take a look at the 19 hotels and other accommodation options you'll find within a mile.

Where is the best place to stay close to Lester E. Cox Medical Center South?

Residence Inn by Marriott Springfield is one of the top choices for your stay based on our traveller data, and this hotel offers free breakfast and a restaurant. It's located just a short 0.5 mi (0.8 km) from Lester E. Cox Medical Center South. Other good choices close by include The Bradford Hotel, an Ascend Collection Hotel and Extended Stay America Select Suites Springfield South.

How many hotels are there close to Lester E. Cox Medical Center South?

Expedia has 19 hotels and other accommodation options within a mile from Lester E. Cox Medical Center South.

If I need to cancel the hotel reservation for my stay near Lester E. Cox Medical Center South, will I receive a refund?

Yes, the majority of hotel reservations are fully refundable if you cancel before the hotel's cancellation deadline, which often is within 24-48 hours of check in. If you booked a non-refundable reservation, you might still have the option to cancel and receive a refund within a 24-hour period of booking. Enter dates in and click on "Search", then filter by "fully refundable" to review the best deals available near Lester E. Cox Medical Center South.

What can I see and do near Lester E. Cox Medical Center South?

You'll want to browse the exhibits at Springfield Art Museum and Discovery Center of Springfield. Sights like Abou Ben Adhem Shrine and Landers Theater highlight some of the local culture. You might spend a leisurely day outdoors at Nathanael Greene/Close Memorial Park and Mizumoto Japanese Stroll Garden.

Springfield Lester E. Cox Medical Center South Hotels

Change your mind

Treat yourself

Be picky

Check prices for these dates

Filter by

Star rating

Guest rating

Our top choices for Lester E. Cox Medical Center South hotels

1. Hampton Inn Springfield-South

2. Homewood Suites by Hilton Springfield Medical District

3. Candlewood Suites Springfield-Medical District

4. Element by Marriott Springfield South

5. Hilton Garden Inn Springfield, MO

6. Residence Inn by Marriott Springfield

7. La Quinta Inn & Suites by Wyndham Springfield South

8. MainStay Suites Springfield South - Battlefield Rd

9. Comfort Inn South - Springfield

10. The Bradford Hotel, an Ascend Collection Hotel

11. Sleep Inn Springfield South I60 near Medical District

12. Extended Stay America Select Suites Springfield South

13. Clarion Pointe Springfield Southeast

14. Hotel Vandivort

15. Drury Inn & Suites Springfield, MO

16. Hampton Inn Springfield-Southeast

17. SpringHill Suites by Marriott Springfield North

18. Holiday Inn Express & Suites Springfield North by IHG

19. Fairfield Inn & Suites by Marriott Springfield North

20. Home2 Suites by Hilton Springfield North

Compare popular hotels close to Lester E. Cox Medical Center South

Top Lester E. Cox Medical Center South Hotel Reviews

The Bradford Hotel, an Ascend Collection Hotel

Comfort Inn South - Springfield

Homewood Suites by Hilton Springfield Medical District

Holiday Inn Express and Suites Springfield Medical District by IHG

Element by Marriott Springfield South

Residence Inn by Marriott Springfield

Peaceful Retreat near Medical Mile in Springfield

Candlewood Suites Springfield-Medical District

Comfortable Home Near CoxHealth & MSU - Fenced Yard

Frequently asked questions