St. Louis Lewis and Clark Interpretive Center Hotels

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Check prices for these dates

Tonight
18 Dec - 19 Dec
Tomorrow
19 Dec - 20 Dec
This weekend
19 Dec - 21 Dec
Next weekend
26 Dec - 28 Dec

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Our top choices for Lewis and Clark Interpretive Center hotels

Lobby lounge
Fairfield Inn & Suites St. Louis Pontoon Beach/Granite City

Fairfield Inn & Suites St. Louis Pontoon Beach/Granite City

Fairfield Inn & Suites St. Louis Pontoon Beach/Granite City
2.5 star property
6.2 km from Lewis and Clark Interpretive Center
9.2 out of 10, Wonderful, (488)
"This hotel was well kept,the breakfast was excellent. Stsff was friendly. "
United States
Dennis M
The price is HK$820
HK$910 total
includes taxes & fees
25 Dec - 26 Dec
Fairfield Inn & Suites St. Louis Pontoon Beach/Granite City
Lobby sitting area
Best Western Plus Pontoon Beach

Best Western Plus Pontoon Beach

Best Western Plus Pontoon Beach
3.0 star property
6.8 km from Lewis and Clark Interpretive Center
8.6 out of 10, Excellent, (800)
"Staff and very nice, good breakfast, soft bed…. I would definitely stay again "
United States
LaSonya
The price is HK$665
HK$738 total
includes taxes & fees
24 Dec - 25 Dec
Best Western Plus Pontoon Beach
Blackout curtains, free WiFi, bed sheets
Red Lion Inn & Suites Pontoon Beach

Red Lion Inn & Suites Pontoon Beach

Red Lion Inn & Suites Pontoon Beach
2.5 star property
5.5 km from Lewis and Clark Interpretive Center
7.8 out of 10, Good, (573)
"Yes, very good, yes good breakfast, yes truck parking."
United States
mark
The price is HK$455
HK$515 total
includes taxes & fees
24 Dec - 25 Dec
Red Lion Inn & Suites Pontoon Beach
Exterior
Bel Air Motel

Bel Air Motel

Bel Air Motel
3.5 star property
6.3 km from Lewis and Clark Interpretive Center
8.6 out of 10, Excellent, (196)
"Great place super clean. Only thing missing no coffee and our room could have had a nice bistro table to sit at"
United States
James
The price is HK$615
HK$752 total
includes taxes & fees
21 Dec - 22 Dec
Bel Air Motel
Exterior
Holiday Inn Express & Suites Edwardsville by IHG

Holiday Inn Express & Suites Edwardsville by IHG

Holiday Inn Express & Suites Edwardsville by IHG
2.5 star property
10.9 km from Lewis and Clark Interpretive Center
9.2 out of 10, Wonderful, (819)
"Always a good stay here!"
United States
Chelsie
The price is HK$902
HK$1,038 total
includes taxes & fees
4 Jan - 5 Jan 2026
Holiday Inn Express & Suites Edwardsville by IHG
Lobby
La Quinta Inn & Suites by Wyndham Pontoon Beach

La Quinta Inn & Suites by Wyndham Pontoon Beach

La Quinta Inn & Suites by Wyndham Pontoon Beach
3.0 star property
6.9 km from Lewis and Clark Interpretive Center
7.6 out of 10, Good, (513)
"The hotel staff was exceptionally accommodating. Would stay here over anywhere in the area. "
United States
Kari
The price is HK$678
HK$780 total
includes taxes & fees
19 Dec - 20 Dec
La Quinta Inn & Suites by Wyndham Pontoon Beach
Lobby
Comfort Inn Edwardsville - St. Louis

Comfort Inn Edwardsville - St. Louis

Comfort Inn Edwardsville - St. Louis
2.5 star property
9.4 km from Lewis and Clark Interpretive Center
8.4 out of 10, Very good, (803)
"Great staff, breakfast was excellent and rooms were clean"
United States
Carlos
The price is HK$794
HK$912 total
includes taxes & fees
11 Jan - 12 Jan 2026
Comfort Inn Edwardsville - St. Louis
BBQ/picnic Area
TownePlace Suites by Marriott St. Louis Edwardsville, IL

TownePlace Suites by Marriott St. Louis Edwardsville, IL

TownePlace Suites by Marriott St. Louis Edwardsville, IL
3.5 star property
10.9 km from Lewis and Clark Interpretive Center
9.0 out of 10, Wonderful, (195)
"The property was amazing. Loved the layout of the room and the desk than roles out, kitchenette and spacious bathroom. Only think missing was hot chocolate!"
United States
Stuart
The price is HK$1,315
HK$1,512 total
includes taxes & fees
26 Dec - 27 Dec
TownePlace Suites by Marriott St. Louis Edwardsville, IL
Gazebo
Country Hearth Inn & Suites Edwardsville St. Louis

Country Hearth Inn & Suites Edwardsville St. Louis

Country Hearth Inn & Suites Edwardsville St. Louis
2.5 star property
10.8 km from Lewis and Clark Interpretive Center
8.6 out of 10, Excellent, (648)
"Location very convenient, clean, would stay again"
United States
Brenda
The price is HK$926
HK$1,064 total
includes taxes & fees
1 Jan - 2 Jan 2026
Country Hearth Inn & Suites Edwardsville St. Louis
Premium bedding, pillow-top beds, blackout curtains, iron/ironing board
Econo Lodge Inn & Suites Granite City - St. Louis

Econo Lodge Inn & Suites Granite City - St. Louis

Econo Lodge Inn & Suites Granite City - St. Louis
2.0 star property
4.7 km from Lewis and Clark Interpretive Center
6.2 out of 10, (246)
"Overall the stay was adequate, right off the highway so convenient."
United States
Henry
The price is HK$510
HK$586 total
includes taxes & fees
28 Dec - 29 Dec
Econo Lodge Inn & Suites Granite City - St. Louis
Lobby
Days Inn by Wyndham Pontoon Beach

Days Inn by Wyndham Pontoon Beach

Days Inn by Wyndham Pontoon Beach
2.0 star property
6.6 km from Lewis and Clark Interpretive Center
6.2 out of 10, (570)
"Bed was soooooooo comfortable and front desk guy that checked me in was great as well "
United States
Maurice
The price is HK$496
HK$550 total
includes taxes & fees
1 Jan - 2 Jan 2026
Days Inn by Wyndham Pontoon Beach
Free daily buffet breakfast
Hampton Inn & Suites St. Louis-Edwardsville

Hampton Inn & Suites St. Louis-Edwardsville

Hampton Inn & Suites St. Louis-Edwardsville
2.5 star property
10.1 km from Lewis and Clark Interpretive Center
7.6 out of 10, Good, (70)
"We enjoyed our stay"
United States
Susan
The price is HK$823
HK$922 total
includes taxes & fees
28 Dec - 29 Dec
Hampton Inn & Suites St. Louis-Edwardsville
Electric vehicle-charging station
Budget Motel Granite City/St Louis Area

Budget Motel Granite City/St Louis Area

Budget Motel Granite City/St Louis Area
2.0 star property
4.7 km from Lewis and Clark Interpretive Center
6.4 out of 10, (15)
"Its nice here"
United States
Sheila
The price is HK$521
HK$568 total
includes taxes & fees
24 Dec - 25 Dec
Budget Motel Granite City/St Louis Area
Lobby
Hampton Inn & Suites St. Louis/Alton

Hampton Inn & Suites St. Louis/Alton

Hampton Inn & Suites St. Louis/Alton
2.5 star property
14 km from Lewis and Clark Interpretive Center
9.0 out of 10, Wonderful, (641)
"Super nice staff! Breakfast was much better than I expected. "
United States
Michelle
The price is HK$887
HK$1,011 total
includes taxes & fees
4 Jan - 5 Jan 2026
Hampton Inn & Suites St. Louis/Alton
Lobby
Super 8 by Wyndham St. Louis North

Super 8 by Wyndham St. Louis North

Super 8 by Wyndham St. Louis North
2.0 star property
16.5 km from Lewis and Clark Interpretive Center
6.4 out of 10, (568)
"Great place"
United States
James
The price is HK$595
HK$696 total
includes taxes & fees
24 Dec - 25 Dec
Super 8 by Wyndham St. Louis North
Lobby
Drury Inn & Suites St. Louis Collinsville

Drury Inn & Suites St. Louis Collinsville

Drury Inn & Suites St. Louis Collinsville
3.0 star property
15.4 km from Lewis and Clark Interpretive Center
9.6 out of 10, Exceptional, (1001)
"Good food and options. Location is amazing."
United States
Jesus
The price is HK$762
HK$877 total
includes taxes & fees
11 Jan - 12 Jan 2026
Drury Inn & Suites St. Louis Collinsville
Exterior
Holiday Inn Express and Suites Alton St Louis Area by IHG

Holiday Inn Express and Suites Alton St Louis Area by IHG

Holiday Inn Express and Suites Alton St Louis Area by IHG
2.5 star property
13.8 km from Lewis and Clark Interpretive Center
9.2 out of 10, Wonderful, (160)
"Staff and location were perfect"
United States
Ileta
The price is HK$840
HK$958 total
includes taxes & fees
1 Jan - 2 Jan 2026
Holiday Inn Express and Suites Alton St Louis Area by IHG
Lobby
The Great Rivers, an Ascend Collection Hotel

The Great Rivers, an Ascend Collection Hotel

The Great Rivers, an Ascend Collection Hotel
3.0 star property
11.5 km from Lewis and Clark Interpretive Center
7.8 out of 10, Good, (759)
"The hotel is being remodeled, so it's hard to give it a fair review."
United States
Stephen
The price is HK$655
HK$746 total
includes taxes & fees
11 Jan - 12 Jan 2026
The Great Rivers, an Ascend Collection Hotel
Lobby
Americas Best Value Inn Collinsville St. Louis

Americas Best Value Inn Collinsville St. Louis

Americas Best Value Inn Collinsville St. Louis
2.0 star property
15.8 km from Lewis and Clark Interpretive Center
6.4 out of 10, (941)
"Was a great place to stay "
United States
Eddei
The price is HK$490
HK$563 total
includes taxes & fees
20 Dec - 21 Dec
Americas Best Value Inn Collinsville St. Louis
Lobby sitting area
First Western Inn

First Western Inn

First Western Inn
2.0 star property
18.1 km from Lewis and Clark Interpretive Center
6.4 out of 10, (361)
"It was a good trip check in was fast and room are very clean"
United States
Letonjalyn
The price is HK$516
HK$583 total
includes taxes & fees
19 Dec - 20 Dec
First Western Inn
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

Top Lewis and Clark Interpretive Center Hotel Reviews

Embassy Suites by Hilton St. Louis Downtown

Embassy Suites by Hilton St. Louis Downtown

10/10 Excellent
"The room was fantastic. It was the first snowy day of the season! The room was clean and fresh with plenty of towels for all of us to shower. The pool was a welcome sight after traveling in the cold weather. The arch and Riverboat reservation were canceled due to inclement weather conditions. We did the pool, snacks and drinks. The room was very spacious with the separate bedroom area. Our room had a nice dining table and chairs. Sofa was very comfortable, one of the girls slept on it as a sofa bed. Bell hop service was wonderful, Steve helped us get everything from the van to our room, and then back again when we checked out. The dining room was very spacious and the breakfast was delicious! The kids made their own waffles with all the toppings! Juice selection and coffee was great. I can’t think of anything that we didn’t enjoy about our stay! Just saying good bye to family when our weekend came to an end. Thanks for making our thanksgiving weekend special for us all. "
Kathy 2-night trip
Posted 1 day ago
Embassy Suites by Hilton St. Louis Downtown

Hotels near other Lewis and Clark Interpretive Center attractions

Lewis and Clark Confluence Tower

Bring a camera when you climb this tower, which offers fantastic views across the Mississippi River and provides insight into a fascinating piece of history.
See properties

Lewis and Clark State Memorial Park

Explore the great outdoors at Lewis and Clark State Memorial Park, a lovely green space in Hartford. Discover the area's museums and monuments.
See properties

Frequently asked questions

What's the area like around Lewis and Clark Interpretive Center?
Lewis and Clark Interpretive Center is located in a welcoming area of Hartford that travellers like for its sporting events. You'll find 13 hotels and other accommodations within a few miles for a convenient home base.
What's the best hotel to stay close to Lewis and Clark Interpretive Center?
Hyatt Regency St. Louis at The Arch is one of the top choices for your stay based on our traveller data, and this hotel offers 3 restaurants and 2 bars. You'll find it 13 mi (20.9 km) from Lewis and Clark Interpretive Center. Other good options around the area include Magnolia Hotel St. Louis, a Tribute Portfolio Hotel and Hampton Inn St. Louis-Downtown (At the Gateway Arch).
How many hotels will I find close to Lewis and Clark Interpretive Center?
Expedia has 13 hotels and other accommodation options a few miles from Lewis and Clark Interpretive Center.
If I need to cancel the hotel reservation for my stay near Lewis and Clark Interpretive Center, will I receive a refund?
Yes! The majority of hotel bookings are refundable provided that you cancel prior to the accommodation's cancellation deadline, which is often 24 or 48 hours before your scheduled arrival. If you have a reservation that's non-refundable, you may still be able to cancel and be given a refund within a 24-hour period of your booking. Put your dates in and click on "Search", then use the filter option "fully refundable" to get the best deals available near Lewis and Clark Interpretive Center.
What can I see and do near Lewis and Clark Interpretive Center?
You might spend a leisurely day outdoors at Lewis and Clark State Memorial Park and Dads Club Park. Create some family memories at CP Pinball and Saint Louis Zoo WildCare Park. Explore nature at Jones-Confluence Point State Park and Columbia Bottom Conservation Area.