The entrance to the Kentucky Science Center with a large circular structure in the foreground.

Louisville Louisville Science Center Hotels

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Check prices for these dates

Next weekend
6 Nov - 8 Nov
In two weeks
13 Nov - 15 Nov

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Our top choices for Louisville Science Center hotels

A wooden staircase with a balustrade leading to a landing.

1. Market Street Inn

Market Street Inn
3.5 star property
2.1 km from Louisville Science Center
9.8 out of 10, Exceptional, (127 reviews)
"Such a lovely stay at the Market Street Inn. A very charming, comfortable and feels like home kind of place. Carol and Steve are just the kindest owners. They were responsive and accommodating and always available if needed. We also loved meeting Lisa, who made breakfast each morning and took care of any housekeeping needs. We felt like we were treated as family and not just guests. The area and location is perfect, SUCH a cute little town. Plenty of restaurants, shops and entertainment within...
United States
Ryan
The price is HK$1,735
HK$1,960 total
includes taxes & fees
3 Nov - 4 Nov
Market Street Inn
A historic building with a grand entrance, steps leading up to the door, and a sign indicating it is a bed and breakfast.

2. DuPont Mansion Bed & Breakfast

DuPont Mansion Bed & Breakfast
4.0 star property
Old Louisville, 2.8 km from Louisville Science Center
9.6 out of 10, Exceptional, (150 reviews)
"5 STAR B&B"
United States
Casey
The price is HK$1,429
HK$1,659 total
includes taxes & fees
4 Nov - 5 Nov
DuPont Mansion Bed & Breakfast
A multi-story hotel with a classic facade, large windows, and a modern glass building adjacent to it.

3. Hotel Distil, Autograph Collection

Hotel Distil, Autograph Collection
4.0 star property
Downtown Louisville, 0.9 km from Louisville Science Center
9.6 out of 10, Exceptional, (517 reviews)
"Very clean / helpful and accommodating staff / excellent restaurant"
United States
Kimberly
The price is HK$1,581
HK$1,860 total
includes taxes & fees
22 Nov - 23 Nov
Hotel Distil, Autograph Collection
A grand lobby with ornate columns, plush seating, and a chandelier.

4. The Brown Hotel

The Brown Hotel
4.5 star property
Downtown Louisville, 1.2 km from Louisville Science Center
9.4 out of 10, Exceptional, (1,441 reviews)
"We had a nice stay!"
United States
katisha
The price is HK$818
HK$963 total
includes taxes & fees
25 Nov - 26 Nov
The Brown Hotel
A spacious indoor patio with a fire pit, wooden pergola, and comfortable seating areas.

5. Homewood Suites by Hilton Louisville Downtown, KY

Homewood Suites by Hilton Louisville Downtown, KY
3.0 star property
Downtown Louisville, 0.2 km from Louisville Science Center
9.4 out of 10, Exceptional, (1,004 reviews)
"Staff very friendly"
United States
peter
The price is HK$894
HK$1,052 total
includes taxes & fees
23 Nov - 24 Nov
Homewood Suites by Hilton Louisville Downtown, KY
A spacious lobby with a high ceiling, a central chandelier, and seating areas with tables and chairs.

6. Omni Louisville Hotel

Omni Louisville Hotel
4.0 star property
Downtown Louisville, 0.8 km from Louisville Science Center
9.4 out of 10, Exceptional, (2,215 reviews)
"Nice location"
United States
Brian
The price is HK$1,594
HK$1,876 total
includes taxes & fees
16 Nov - 17 Nov
Omni Louisville Hotel
A hotel with a prominent sign, a central courtyard with a sculpture, and a dome structure in the background.

7. Hotel Bourré Bonne Louisville, Curio Collection by Hilton

Hotel Bourré Bonne Louisville, Curio Collection by Hilton
4.0 star property
Downtown Louisville, 0.8 km from Louisville Science Center
9.4 out of 10, Exceptional, (173 reviews)
"Very good breakfast in hotel lobby restaurant. Extremely nice servers. Reasonably priced."
United States
Paul
The price is HK$1,023
HK$1,203 total
includes taxes & fees
23 Nov - 24 Nov
Hotel Bourré Bonne Louisville, Curio Collection by Hilton
An outdoor terrace with tables and chairs, large windows, and a view of the city skyline at sunset.

8. Tempo By Hilton Louisville Downtown Nulu

Tempo By Hilton Louisville Downtown Nulu
3.5 star property
Phoenix Hill, 2.1 km from Louisville Science Center
9.4 out of 10, Exceptional, (1,146 reviews)
"Great stay!"
United States
Addison
The price is HK$1,036
HK$1,219 total
includes taxes & fees
29 Nov - 30 Nov
Tempo By Hilton Louisville Downtown Nulu
A modern building with a sign reading "Stellar Suites" and a crescent moon logo.

9. Stellar Suites

Stellar Suites
4.5 star property
East Market District, 2.2 km from Louisville Science Center
9.4 out of 10, Exceptional, (158 reviews)
"Location was great near meant restaurants and nightspots"
United States
Kevin
The price is HK$907
HK$1,463 total
includes taxes & fees
9 Nov - 10 Nov
Stellar Suites
A classical gold statue in front of a multi-story building with large windows and a brick facade.

10. 21c Museum Hotel Louisville

21c Museum Hotel Louisville
4.5 star property
Downtown Louisville, < 0.1 km from Louisville Science Center
9.4 out of 10, Exceptional, (1,004 reviews)
"Nice modern rooms and excellent cocktails in the bar."
United States
Erick
The price is HK$1,194
HK$1,444 total
includes taxes & fees
23 Nov - 24 Nov
21c Museum Hotel Louisville
A modern interior with a fireplace, bookshelves, a green sofa, and leather chairs.

11. The Grady

The Grady
4.0 star property
Downtown Louisville, 0.2 km from Louisville Science Center
9.4 out of 10, Exceptional, (1,003 reviews)
"I really enjoyed my stay and hope to return soon."
United States
Donna
The price is HK$1,222
HK$1,438 total
includes taxes & fees
15 Nov - 16 Nov
The Grady
A spacious indoor area with a large dining table, multiple chairs, a fireplace, and a kitchen area with a bar.

12. Cambria Hotel Louisville Downtown-Whiskey Row

Cambria Hotel Louisville Downtown-Whiskey Row
3.0 star property
Downtown Louisville, 1.2 km from Louisville Science Center
9.2 out of 10, Wonderful, (1,015 reviews)
"Clean and bathrooms are nice I will be staying again."
United States
Trista
The price is HK$747
HK$879 total
includes taxes & fees
22 Nov - 23 Nov
Cambria Hotel Louisville Downtown-Whiskey Row
An outdoor dining area with a long table and wicker chairs, overhead lighting, and a view of the city.

13. Hotel Genevieve part of JdV by Hyatt

Hotel Genevieve part of JdV by Hyatt
4.0 star property
East Market District, 2.1 km from Louisville Science Center
9.2 out of 10, Wonderful, (1,084 reviews)
"We’ve stayed here a number of times and we love it. Right in the middle of NuLu, it’s the perfect spot."
United States
Jesse
The price is HK$1,247
HK$1,468 total
includes taxes & fees
15 Nov - 16 Nov
Hotel Genevieve part of JdV by Hyatt
A brick building with outdoor seating and a fire pit.

14. TownePlace Suites by Marriott Louisville North

TownePlace Suites by Marriott Louisville North
3.0 star property
2.2 km from Louisville Science Center
9.2 out of 10, Wonderful, (746 reviews)
"Room was clean, breakfast was good, great walkable location with onsite free parking!"
United States
Lori M
The price is HK$879
HK$993 total
includes taxes & fees
22 Nov - 23 Nov
TownePlace Suites by Marriott Louisville North
A covered patio with a stone wall, a glass table, and a bench.

15. Central Park Bed & Breakfast

Central Park Bed & Breakfast
3.5 star property
Old Louisville, 3 km from Louisville Science Center
9.2 out of 10, Wonderful, (99 reviews)
"Amazing stay and hospitality. Will stay again"
United States
Stephen
The price is HK$1,340
HK$1,555 total
includes taxes & fees
8 Nov - 9 Nov
Central Park Bed & Breakfast
A cozy living room with a fireplace, a black leather sofa, and a patterned rug.

16. Moxy Louisville Downtown

Moxy Louisville Downtown
3.5 star property
Downtown Louisville, 0.9 km from Louisville Science Center
9.2 out of 10, Wonderful, (860 reviews)
"Hotel was super clean and staff were friendly in a great location"
United States
Sheree
The price is HK$753
HK$886 total
includes taxes & fees
29 Nov - 30 Nov
Moxy Louisville Downtown
A modern hotel with a prominent 'Aloft Hotels' sign, multiple floors, and a corner location with a view of the city skyline.

17. Aloft by Marriott Louisville Downtown

Aloft by Marriott Louisville Downtown
3.0 star property
Downtown Louisville, 0.9 km from Louisville Science Center
9.2 out of 10, Wonderful, (1,002 reviews)
"Great clean hotel awesome staff."
United States
Anthony
The price is HK$891
HK$1,048 total
includes taxes & fees
26 Nov - 27 Nov
Aloft by Marriott Louisville Downtown
A modern hotel lobby with a reception desk, seating area, and a large window providing natural light.

18. AC Hotel Louisville Downtown

AC Hotel Louisville Downtown
3.5 star property
East Market District, 2.1 km from Louisville Science Center
9.2 out of 10, Wonderful, (732 reviews)
"This our second time staying here and it was awesome"
United States
Julie
The price is HK$1,123
HK$1,321 total
includes taxes & fees
8 Nov - 9 Nov
AC Hotel Louisville Downtown
A balcony with a view of a river, a bridge, and a cityscape.

19. Galt House Hotel Trademark Collection by Wyndham

Galt House Hotel Trademark Collection by Wyndham
4.0 star property
Downtown Louisville, 0.5 km from Louisville Science Center
9.0 out of 10, Wonderful, (4,458 reviews)
"Great place to stay!!!"
United States
Shun
The price is HK$1,068
HK$1,256 total
includes taxes & fees
15 Nov - 16 Nov
Galt House Hotel Trademark Collection by Wyndham
A spacious lobby with a blue sofa, a wooden coffee table, and a chandelier.

20. Embassy Suites Louisville Downtown

Embassy Suites Louisville Downtown
4.0 star property
Downtown Louisville, 0.8 km from Louisville Science Center
9.0 out of 10, Wonderful, (1,387 reviews)
"Great room, excellent staff, exceptional breakfast, very clean."
United States
Chase
The price is HK$1,023
HK$1,203 total
includes taxes & fees
23 Nov - 24 Nov
Embassy Suites Louisville Downtown
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

Compare popular hotels close to Louisville Science Center

Property
Property class
Guest rating
Breakfast included
Pool
Spa
Pet-friendly
WiFi included
A wooden staircase with a balustrade leading to a landing.
Market Street Inn
3.5 star property
9.8
Exceptional
127 reviews
View
A historic building with a grand entrance, steps leading up to the door, and a sign indicating it is a bed and breakfast.
DuPont Mansion Bed & Breakfast
4.0 star property
9.6
Exceptional
150 reviews
View
A multi-story hotel with a classic facade, large windows, and a modern glass building adjacent to it.
Hotel Distil, Autograph Collection
4.0 star property
9.6
Exceptional
517 reviews
View
A grand lobby with ornate columns, plush seating, and a chandelier.
The Brown Hotel
4.5 star property
9.4
Exceptional
1,441 reviews
View
A spacious indoor patio with a fire pit, wooden pergola, and comfortable seating areas.
Homewood Suites by Hilton Louisville Downtown, KY
3.0 star property
9.4
Exceptional
1,004 reviews
View

Hotels recommended for families near Louisville Science Center

A balcony with a view of a river, a bridge, and a cityscape.

Galt House Hotel Trademark Collection by Wyndham

Galt House Hotel Trademark Collection by Wyndham
4.0 star property
Downtown Louisville
9.0 out of 10, Wonderful, (4,458)
The price is HK$1,068
HK$1,256 total
includes taxes & fees
15 Nov - 16 Nov
Galt House Hotel Trademark Collection by Wyndham

Top Louisville Science Center Hotel Reviews

Towneplace Suites By Marriott Louisville Downtown

Towneplace Suites By Marriott Louisville Downtown

10/10 Excellent
"Nice spacious rooms. Comfortable beds. Breakfast was great. Would stay again the next time we pass through."
Kenneth 1-night trip
Posted less than an hour ago
Towneplace Suites By Marriott Louisville Downtown

Other attractions near Louisville Science Center

A tall wooden baseball bat leaning against a brick building with a sign reading "Hillerich & Brassler Co."

Louisville Slugger Museum

9.2/10 (2,299 reviews)
Baseball is part of the American fabric. See where one important tool for this sport is produced in the factory that makes ball games possible.
See properties

Frequently asked questions

What's the area like around Louisville Science Center?
Louisville Science Center is located in an area of Louisville known for its stunning river views, sporting events and great live music scene. If you're looking for a convenient place to stay, take a look at the 292 hotels and other accommodation options you'll find within a mile.
Where is the best place to stay near Louisville Science Center?
Adjacent to Louisville Science Center, Holiday Inn Express & Suites Louisville Downtown by IHG is one of the top choices for your stay based on our traveller data, and this hotel offers free breakfast and a 24-hour fitness centre. Other good choices within a short distance include Galt House Hotel Trademark Collection by Wyndham and Omni Louisville Hotel.
How many hotels can I expect to find close to Louisville Science Center?
Expedia has 292 hotels and other accommodation options within a mile from Louisville Science Center.
If I need to cancel the hotel reservation for my stay near Louisville Science Center, will I receive a refund?
Yes! Most hotel room reservations are fully refundable as long as you cancel before the hotel's cancellation deadline, which is usually within 24-48 hours of check in. If you booked a non-refundable reservation, you might be able to still cancel and get a refund within a 24-hour period of booking. Add dates, click "Search", then use the filter option "fully refundable" to get the top deals on offer near Louisville Science Center.
What can I see and do near Louisville Science Center?
21c Museum Hotel, Louisville Slugger Museum and Muhammad Ali Center feature a variety of fascinating exhibits to see while you're in town. Explore landmarks like Belle of Louisville, Whiskey Row and Big Four Bridge. You can catch a show at Louisville Palace, Derby Dinner Playhouse and Headliners Music Hall.