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Mississippi River Hotels

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Our top choices for Mississippi River hotels

1. Sleep Inn & Suites Hannibal West

Sleep Inn & Suites Hannibal West
2.5 star property
30.3 km from Mississippi River
9.6 out of 10, Exceptional, (1,001 reviews)
"Great staff and the rooms were clean and comfortable"
United States
Steve
The price is HK$961
HK$1,118 total
includes taxes & fees
16 Aug - 17 Aug
Sleep Inn & Suites Hannibal West

2. River's Edge Motel

River's Edge Motel
2.0 star property
13.6 km from Mississippi River
9.0 out of 10, Wonderful, (379 reviews)
"We were just driving through and needed a place to stay for the night. It was an easy check in and very friendly staff so perfect for us."
United States
Brent
The price is HK$627
HK$712 total
includes taxes & fees
14 Aug - 15 Aug
River's Edge Motel

3. The Eagles Nest Inn

The Eagles Nest Inn
3.0 star property
14.2 km from Mississippi River
9.4 out of 10, Exceptional, (26 reviews)
"Very nice place to stay loved the brick walls and wood floors leading up to the rooms"
United States
Gary
The price is HK$882
HK$1,002 total
includes taxes & fees
9 Aug - 10 Aug
The Eagles Nest Inn

4. Best Western On The River

Best Western On The River
2.5 star property
25.3 km from Mississippi River
8.8 out of 10, Excellent, (1,011 reviews)
"Great location for all our activities!"
United States
Carolyn
The price is HK$1,004
HK$1,158 total
includes taxes & fees
9 Aug - 10 Aug
Best Western On The River

5. Riverside Inn Hannibal

Riverside Inn Hannibal
2.5 star property
25.1 km from Mississippi River
9.6 out of 10, Exceptional, (188 reviews)
"Easy no hastle accommodations. Downtown. Hot tub."
United States
Robert
The price is HK$1,263
HK$1,728 total
includes taxes & fees
9 Aug - 10 Aug
Riverside Inn Hannibal

6. Quality Inn & Suites Hannibal West

Quality Inn & Suites Hannibal West
2.5 star property
30 km from Mississippi River
8.0 out of 10, Very good, (1,005 reviews)
"Older property with very hospitable staff and excellent hot breakfast!"
United States
Karen
The price is HK$564
HK$656 total
includes taxes & fees
16 Aug - 17 Aug
Quality Inn & Suites Hannibal West

7. Oak Hill Inn & Suites

Oak Hill Inn & Suites
2.5 star property
71.8 km from Mississippi River
9.2 out of 10, Wonderful, (1,001 reviews)
"The staff is so welcoming and very- highly recommended"
United States
Mary
The price is HK$794
HK$905 total
includes taxes & fees
10 Aug - 11 Aug
Oak Hill Inn & Suites

8. Heritage Hotel Quincy

Heritage Hotel Quincy
2.0 star property
47.8 km from Mississippi River
8.8 out of 10, Excellent, (424 reviews)
"Would stay again"
United States
Dustine
The price is HK$550
HK$627 total
includes taxes & fees
14 Aug - 15 Aug
Heritage Hotel Quincy

9. Town & Country Inn and Suites

Town & Country Inn and Suites
2.5 star property
45.2 km from Mississippi River
9.2 out of 10, Wonderful, (937 reviews)
"The room was large and clean and the breakfast tasty!"
United States
Tracy
The price is HK$1,052
HK$1,199 total
includes taxes & fees
12 Aug - 13 Aug
Town & Country Inn and Suites

10. Comfort Inn & Suites - Hannibal

Comfort Inn & Suites - Hannibal
2.5 star property
26.2 km from Mississippi River
7.6 out of 10, Good, (730 reviews)
"As always the beds at comfort inn are so comfortable. Enjoyed our stay."
United States
Tracey
The price is HK$610
HK$727 total
includes taxes & fees
30 Aug - 31 Aug
Comfort Inn & Suites - Hannibal

11. Lighthouse Inn & Suites

Lighthouse Inn & Suites
4.0 star property
25.8 km from Mississippi River
9.0 out of 10, Wonderful, (36 reviews)
"Wonderful place to stay!"
United States
Kari
The price is HK$1,408
HK$1,624 total
includes taxes & fees
6 Aug - 7 Aug
Lighthouse Inn & Suites

12. Holiday Inn Express and Suites Alton St Louis Area by IHG

Holiday Inn Express and Suites Alton St Louis Area by IHG
2.5 star property
110.6 km from Mississippi River
9.0 out of 10, Wonderful, (226 reviews)
"Great place to stay for the night"
United States
Thomas
The price is HK$1,027
HK$1,171 total
includes taxes & fees
16 Aug - 17 Aug
Holiday Inn Express and Suites Alton St Louis Area by IHG

13. Drury Inn & Suites St. Louis St. Peters

Drury Inn & Suites St. Louis St. Peters
3.0 star property
95.3 km from Mississippi River
9.4 out of 10, Exceptional, (1,011 reviews)
"Front desk was very helpful and friendly. Breakfast was very good and staff was extremely friendly!"
United States
DANA
The price is HK$863
HK$992 total
includes taxes & fees
16 Aug - 17 Aug
Drury Inn & Suites St. Louis St. Peters

14. Hampton Inn & Suites St. Louis/Alton

Hampton Inn & Suites St. Louis/Alton
2.5 star property
110.3 km from Mississippi River
9.0 out of 10, Wonderful, (701 reviews)
"Everything was wonderful"
United States
Willie
The price is HK$1,055
HK$1,202 total
includes taxes & fees
29 Aug - 30 Aug
Hampton Inn & Suites St. Louis/Alton

15. Motel 6 Hannibal, MO

Motel 6 Hannibal, MO
2.0 star property
26.1 km from Mississippi River
7.4 out of 10, Good, (1,005 reviews)
"Clean room good staff"
United States
Darion
The price is HK$455
HK$525 total
includes taxes & fees
10 Aug - 11 Aug
Motel 6 Hannibal, MO

16. Drury Plaza Hotel St. Louis St. Charles

Drury Plaza Hotel St. Louis St. Charles
3.0 star property
104 km from Mississippi River
9.6 out of 10, Exceptional, (1,013 reviews)
"it was a nice place to stay"
United States
Jamie
The price is HK$1,098
HK$1,273 total
includes taxes & fees
9 Aug - 10 Aug
Drury Plaza Hotel St. Louis St. Charles

17. Days Inn by Wyndham Hannibal

Days Inn by Wyndham Hannibal
2.0 star property
26.4 km from Mississippi River
7.4 out of 10, Good, (267 reviews)
"The room was clean with comfortable beds. The breakfast provided good options along with enough seating for guests."
United States
Dan
The price is HK$484
HK$559 total
includes taxes & fees
13 Aug - 14 Aug
Days Inn by Wyndham Hannibal

18. The Green Tree Inn

The Green Tree Inn
3.0 star property
95 km from Mississippi River
9.4 out of 10, Exceptional, (214 reviews)
"Really good breakfast all 3 mornings we were there. They packed a delicious picnic lunch for us to take on a hike. Room was clean and neat. Very charming small town. Would stay there again."
United States
Vernon
The price is HK$1,536
HK$1,704 total
includes taxes & fees
11 Aug - 12 Aug
The Green Tree Inn

19. Quality Inn & Suites Quincy - Downtown

Quality Inn & Suites Quincy - Downtown
2.5 star property
47.8 km from Mississippi River
8.8 out of 10, Excellent, (480 reviews)
"Great staff and nice accommodations. "
United States
Tom
The price is HK$969
HK$1,104 total
includes taxes & fees
9 Aug - 10 Aug
Quality Inn & Suites Quincy - Downtown

20. Stoney Creek Inn Quincy

Stoney Creek Inn Quincy
2.0 star property
46.5 km from Mississippi River
8.6 out of 10, Excellent, (1,002 reviews)
"Very clean room was very super quiet the breakfast was absolutely fantastic the room was super clean!"
United States
Axel
The price is HK$946
HK$1,078 total
includes taxes & fees
9 Aug - 10 Aug
Stoney Creek Inn Quincy
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Compare popular hotels close to Mississippi River

Property
Property class
Guest rating
Breakfast included
Pool
Spa
Pet-friendly
WiFi included
Exterior
Sleep Inn & Suites Hannibal West
2.5 star property
9.6
Exceptional
1,001 reviews
View
Property grounds
River's Edge Motel
2.0 star property
9.0
Wonderful
379 reviews
View
Lunch and dinner served
The Eagles Nest Inn
3.0 star property
9.4
Exceptional
26 reviews
View
Desk, iron/ironing board, WiFi, bed sheets
Best Western On The River
2.5 star property
8.8
Excellent
1,011 reviews
View
55-inch TV with cable channels, Netflix, Hulu
Riverside Inn Hannibal
2.5 star property
9.6
Exceptional
188 reviews
View

Top Mississippi River Hotel Reviews

Other attractions near Mississippi River

Find out more about Mississippi River

Top reasons to visit Mississippi River

  • Diverse Activities: The Mississippi River offers thrilling baseball games, live music performances, and bird watching, catering to a variety of interests.
  • Rich Cultural Experience: Explore historic houses, caves, and museums that celebrate the region's vibrant culture and heritage.
  • Scenic Excursions: Enjoy relaxing boat trips along the river, taking in stunning landscapes and the charm of local communities.
  • Adventure Opportunities: Engage in outdoor activities that allow you to discover the river's remarkable features.
  • Varied Accommodations: Choose from charming bed and breakfasts to well-appointed hotels, ensuring a comfortable stay for all travellers.

Find great hotels near Mississippi River

Explore a variety of hotel accommodations along the enchanting Mississippi River, catering to every type of traveller. From charming bed and breakfasts to well-appointed hotels like the Hampton Inn, you’ll find options that are family-friendly, romantic, and pet-friendly. Enjoy unique wilderness cabins that immerse you in nature, alongside La Salle-style amenities that enhance your stay. Experience the perfect blend of comfort and adventure in this captivating region.

  • Best Western On The River: A budget-friendly hotel tailored for families and business travellers alike, Best Western On The River boasts a commendable guest rating of 8.6 out of 10. Located 26km from the Mississippi River, it provides a welcoming atmosphere with amenities designed for children, including a safe pool area. This hotel combines comfort with convenience, making it a practical choice for those looking to explore the area while enjoying a range of services suitable for both leisure and work.
  • Super 8 by Wyndham Bowling Green: Known for its affordability, Super 8 by Wyndham Bowling Green offers a guest rating of 8.4 out of 10. Situated 24km from the Mississippi River, this hotel is an excellent option for budget-conscious travellers. Guests can indulge in complimentary daily breakfast options and enjoy various entertainment amenities, including premium TV channels and multiple television setups. Its inviting atmosphere and practical offerings make it a convenient stop for visitors seeking comfort without breaking the bank.
  • River's Edge Motel: With a remarkable guest rating of 9.0 out of 10, River's Edge Motel stands out as a pet-friendly accommodation option only 13km from the Mississippi River. This motel is ideal for those travelling with pets, as it has specific policies and amenities in place to accommodate furry companions. The welcoming and relaxed environment, coupled with its close proximity to the river, adds to the appeal for visitors looking for a homely stay while exploring the local area.

Where to stay near Mississippi River

Embark on an unforgettable journey along the majestic Mississippi River, where friendly locals and family-friendly atmospheres abound. Discover the vibrant Minnesota River and explore the rich culture of the Mississippi Delta. Enjoy relaxing excursions along the main river and the scenic beauty of the Iowa River. Each destination offers a unique vibe, perfect for creating cherished memories amidst stunning landscapes and welcoming communities.

  • Rockport: Situated a mere 13km from the mighty Mississippi River, Rockport is a vibrant city that attracts visitors year-round, particularly peaking during the delightful months of May, July, and September. This charming destination is perfect for families and outdoor enthusiasts seeking a city-themed experience. Visitors can explore a variety of attractions, including urban parks, a fascinating history museum, and a modern college university. With opportunities for education, theatre, and golf, Rockport offers a delightful blend of leisure and cultural experiences for all ages.
  • Frankford: Located 16km away from the Mississippi River, Frankford is an inviting city that welcomes tourists throughout the year, especially from March to April and in July. Known for its outdoor activities and family-friendly attractions, Frankford provides a unique city-themed escape. Popular venues include an event conference centre, urban parks, and a picturesque lake, perfect for relaxation and fun. Visitors can indulge in activities such as golf and arcade adventures, ensuring an exciting experience for both young and old.
  • Atlas: A quaint village located 16km from the Mississippi River, Atlas offers a serene getaway for those seeking scenic outdoor adventures. Although visitor numbers are consistent throughout the year, the summer months of June to August see a slight increase in tourism. The village is renowned for its stunning river views, making it an ideal spot for nature lovers and those wishing to unwind. Atlas invites you to immerse yourself in its tranquil landscapes and enjoy the beauty of the great outdoors.

Things to do in Mississippi River

Shopping

The nearest shopping spot is the River Market in Vicksburg, where you can find local crafts and delicious food. If you're up for a drive, head to the Mall at Barnes Crossing in Tupelo, featuring a variety of retail stores and dining options for a more extensive shopping experience.

Recreation

Explore the serene surroundings of the Riverbend Wellness Centre, offering yoga classes and meditation sessions by the river. Enjoy leisurely strolls along the scenic trails, or indulge in rejuvenating spa treatments that utilise local botanicals for a truly refreshing experience.

Adventure

The Mississippi River offers thrilling kayaking and canoeing adventures amidst stunning landscapes. Explore charming river towns and enjoy fishing, or embark on a guided riverboat cruise to experience the rich history and culture along the banks, all while soaking in the scenic beauty of this iconic waterway.

Nightlife

The Mississippi River nightlife offers vibrant experiences, from the lively bars in New Orleans' French Quarter to the laid-back vibes of Memphis' Beale Street. Enjoy live music, dance at local clubs, or unwind with a drink at a riverside venue, soaking in the unique atmosphere that each city provides.

*Distances are measured in a straight line; actual driving distances may vary depending on the route.

Booking tips and Expedia advantages for Mississippi River

To save money on your trip to the Mississippi River, consider visiting between December and February when accommodation prices are lower, and aim to book your stay on a Sunday for the best rates. Utilise Expedia's search tools to find eco-certified hotels and sort results by price to uncover the best deals. Combining your hotel, flights, and activities into an Expedia package can lead to significant savings. Additionally, explore free activities along the river to enhance your experience without overspending.

  • The most and least expensive months on average to stay in a hotel: The cheapest months to stay around Mississippi River are December to February, where the prices are slightly lower. This is in comparison to May to July, where prices are slightly higher.
  • The most and least expensive days on average to stay in a hotel: The least expensive day to stay around Mississippi River is Sunday. The most expensive day to stay around Mississippi River is Saturday.
  • Find cheap hotels on Expedia: Utilise Expedia’s search wizard to refine your preferences, such as your budget, desired location, and preferred hotel type. For instance, selecting the Eco-certified option will showcase sustainable and environmentally-friendly hotels available at this moment. To find the most economical prices and offers, sort the price filter from lowest to highest.
  • Consider bundling your trip: You can enjoy significant savings by combining your hotel booking along the Mississippi River with your flights and activities through an Expedia package.

Find the best attractions near Mississippi River

Visitors to the Mississippi River can explore a variety of attractions, including historic houses, caves, and museums that reflect the region's rich culture. For those seeking adventure, the meandering river offers opportunities for outdoor activities while discovering its largest and most amazing features. Don't miss the chance to learn about the Minnesota rivers and experience the beauty of one of the largest rivers in the United States.

  • Mark Twain Cave: Discover the enchanting depths of Mark Twain Cave, located 23km from the Mississippi River. This natural wonder offers an exhilarating adventure, with its winding passages and stunning rock formations, ideal for those who appreciate the great outdoors.
  • Rockcliffe Mansion: Immerse yourself in history at Rockcliffe Mansion, situated 26km from the river. This grand historic house reflects exquisite architecture and offers a glimpse into the opulent lifestyle of the past, surrounded by beautifully landscaped gardens.
  • Mark Twain Memorial Lighthouse: Visit the Mark Twain Memorial Lighthouse, located 26km from the Mississippi River. This charming historic lighthouse celebrates the literary legacy of Mark Twain and provides picturesque views of the river, making it a delightful spot for reflection and photography.

The nearest major airports for your trip to Mississippi River

Flying into the Mississippi River region offers several airport options. St. Louis Lambert International Airport (STL) is situated 113km away, with nearby hotels like The Ritz-Carlton and Ameristar Casino Resort, both approximately 11km from the airport. Columbia Regional Airport (COU), located 122km away, has excellent accommodations such as The Broadway Columbia and voco The Tiger Hotel, both around 18km from the airport. Springfield Abraham Lincoln Capital Airport (SPI) is 130km distant, with hotel choices including the President Abraham Lincoln Springfield - DoubleTree by Hilton, just 5km away. Various transportation services are available to ensure easy access from these hotels to their respective airports.

Frequently asked questions

What's the area like around Mississippi River?
Mississippi River is located in an area that travellers like for its baseball games. When you want to settle in and find a place to stay, take a look at some of the hotels and other accommodation options that Expedia offers in the area.
What's the best hotel to stay close to Mississippi River?
Hollywood Casino & Hotel St. Louis is one of the top choices for your stay based on our traveller data, and this hotel offers a casino and 7 restaurants. You'll find it 65.7 mi (105.7 km) from Mississippi River. Other good options around the area include Hyatt Regency St. Louis at The Arch and Clayton Plaza Hotel & Extended Stay.
If I need to cancel the hotel reservation for my stay near Mississippi River, will I receive a refund?
Yes! Most room reservations are fully refundable as long as you cancel before the hotel's cancellation deadline, which in most cases is within 24 or 48 hours of your scheduled arrival. If you have a reservation that's non-refundable, it may still be possible to cancel it and get a refund within a 24-hour period of booking. Add dates, click "Search", then use the "fully refundable" filter to review the best deals near Mississippi River.