Santa Ana
Panama City
Visit Santa Ana
Stay near popular Santa Ana attractions
Things to do
Panama Canal: The Most Complete Wildlife Experience
HK$282
per adult
100% of travellers recommend
Panama City: All-Inclusive Catamaran Cruise to Taboga Island
HK$776
per adult
94% of travellers recommend
Panama City Visit an Indian town Embera and waterfall with lunch
HK$330
per adult
96% of travellers recommend
From Panama City: San Blas Islands Tour with Island Hopping
HK$1,137
per adult
98% of travellers recommend
Half day of Panama city and canal tour: shared and private
HK$523
per adult
96% of travellers recommend
Panama City: Poin Full Package Experience
HK$1,216
per adult
98% of travellers recommend
Top hotels in Santa Ana
Hotel Caracas - Casco Viejo
Plaza De Santa Ana Panama City Provincia di Panama
The price is HK$408 per night from 4 Nov to 5 Nov
HK$408
HK$449 total
4 Nov - 5 Nov
includes taxes & fees
Stay at this hotel in Panama City. Enjoy free Wi-Fi, breakfast (surcharge) and a 24-hour front desk. Popular attractions Albrook Shopping Mall and Cinta Costera ...
7.6/10 Good! (30 reviews)
""While the property was nice overall, a few basic amenities fell short. We had no hot water during our stay, and the breakfast was quite minimal. Additionally, it was surprising to be told that coffee creamer cost extra, even though they ended up waiving the fee at checkout."."
Reviewed on 3 Nov 2026
Casco View Life Residences
C. 16 Oeste Panama City Provincia de Panamá
The price is HK$657 per night from 29 Nov to 30 Nov
HK$657
HK$958 total
29 Nov - 30 Nov
includes taxes & fees
Stay at this business-friendly condo in Panama City. Enjoy free Wi-Fi, breakfast (surcharge) and a 24-hour front desk. Popular attractions Albrook Shopping Mall ...
9/10 Wonderful! (114 reviews)
"The staff was very friendly and helpful which made our stay very pleasant and enjoyable."
Reviewed on 31 Oct 2026
Hotel Riu Plaza Panama
Calle 50, Urb. Marbella Panama City Panama
The price is HK$1,035 per night from 1 Dec to 2 Dec
HK$1,035
HK$1,139 total
1 Dec - 2 Dec
includes taxes & fees
Stay at this luxury hotel in Panama City. Enjoy free breakfast, free Wi-Fi and 3 restaurants. Our guests praise the breakfast and the pool in their reviews. ...
Hotel El Panama by Faranda Grand, a member of Radisson Individuals
Via Espana 111 Panama City Panama
The price is HK$836 per night from 2 Dec to 3 Dec
HK$836
HK$919 total
2 Dec - 3 Dec
includes taxes & fees
Stay at this spa hotel in Panama City. Enjoy free breakfast, free parking and a full-service spa. Our guests praise the helpful staff in their reviews. Popular ...
7.8/10 Good! (1,008 reviews)
"Clean and welcoming"
Reviewed on 3 Nov 2026
Megapolis Hotel Panamá
Avenida Balboa Panama City
The price is HK$1,035 per night from 17 Nov to 18 Nov
HK$1,035
HK$1,139 total
17 Nov - 18 Nov
includes taxes & fees
Stay at this luxury hotel in Panama City. Enjoy free breakfast, free Wi-Fi and free parking. Our guests praise the breakfast and the helpful staff in their reviews. ...
8.6/10 Excellent! (1,835 reviews)
"Asked for a pharmacy and they didn’t know or just didn’t want to give info. There were three just on the other side of the building and 24 hours"
Reviewed on 3 Nov 2026
Crowne Plaza Panama Airport by IHG
Ave. Domingo Diaz Tocumen Panama
The price is HK$1,067 per night from 7 Nov to 8 Nov
HK$1,067
HK$1,226 total
7 Nov - 8 Nov
includes taxes & fees
Stay at this family-friendly hotel in Tocumen. Enjoy free Wi-Fi, breakfast (surcharge) and a free airport shuttle. Our guests praise the breakfast and the pool ...
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Where to stay in Santa Ana
Find the best Santa Ana areas for the activities you enjoy most.
Casco Viejo
Unique features of Casco Viejo include the historical sites and bars. Make a stop by Independence Square or Interoceanic Canal Museum while you're exploring the area.
Photo by Fabiola Tile
Open Photo by Fabiola Tile
Bella Vista
Travellers love Bella Vista for its popular shops, and you can see more of Panama City by jumping on the metro at Iglesia del Carmen Station or Vía Argentina Station. You might spend time checking out top sights like Via Espana and Iglesia del Carmen.
El Cangrejo
The ample dining options and casino gaming are top of the list for many visitors to El Cangrejo. A stop by Via Espana or Crown Casino might round out your trip.
San Francisco
San Francisco is noteworthy for its restaurants, and you can make a stop at top attractions like Multiplaza Pacific Mall and Calle 50.
San Felipe
While visiting San Felipe, you might make a stop by sights like Independence Square and Interoceanic Canal Museum.
