Otay Mesa West

San Diego

Photo by Leonardo De Leon
Photo by Leonardo De Leon

Popular places to visit

Things to do


Top hotels in Otay Mesa West

Bay Club Hotel & Marina

Bay Club Hotel & Marina

3.5 out of 5
2131 Shelter Island Dr San Diego CA
The price is HK$875 per night from 12 Dec to 13 Dec
HK$875
HK$1,006 total
12 Dec - 13 Dec
includes taxes & fees
Stay at this business-friendly hotel in San Diego. Enjoy free Wi-Fi, a marina and a health club. Our guests praise the breakfast and the restaurant in their ...
9/10 Wonderful! (3,181 reviews)
Everything was great for my stay! I appreciate the staff and their accommodations.

Reviewed on 9 Dec 2025

Bay Club Hotel & Marina
Legacy Resort Hotel & Spa

Legacy Resort Hotel & Spa

4 out of 5
875 Hotel Circle South San Diego CA
The price is HK$1,184 per night from 14 Dec to 15 Dec
HK$1,184
HK$1,361 total
14 Dec - 15 Dec
includes taxes & fees
Stay at this spa hotel in San Diego. Enjoy free Wi-Fi, a full-service spa and breakfast (surcharge). Our guests praise the pool and the restaurant in their reviews. ...
9/10 Wonderful! (2,957 reviews)
All was great

Reviewed on 8 Dec 2025

Legacy Resort Hotel & Spa
The DEXTRO Little Italy, BW Premier Collection

The DEXTRO Little Italy, BW Premier Collection

3 out of 5
1617 1st Avenue San Diego CA
The price is HK$761 per night from 14 Dec to 15 Dec
HK$761
HK$882 total
14 Dec - 15 Dec
includes taxes & fees
Stay at this business-friendly hotel in San Diego. Enjoy free Wi-Fi, breakfast (surcharge) and a 24-hour fitness centre. Our guests praise the helpful staff ...
8.8/10 Excellent! (713 reviews)
Everything was perfect

Reviewed on 6 Dec 2025

The DEXTRO Little Italy, BW Premier Collection
Lafayette Hotel & Club

Lafayette Hotel & Club

4 out of 5
2223 El Cajon Blvd San Diego CA
The price is HK$1,758 per night from 15 Dec to 16 Dec
HK$1,758
HK$2,018 total
15 Dec - 16 Dec
includes taxes & fees
Stay at this business-friendly hotel in San Diego. Enjoy free Wi-Fi, 2 restaurants and 3 bars/lounges. Our guests praise the helpful staff in their reviews. ...
9.2/10 Wonderful! (1,320 reviews)
These guy do a terrific job always love coming here. The staff is so friendly and accommodating. We will be back

Reviewed on 8 Dec 2025

Lafayette Hotel & Club
Hard Rock Hotel San Diego

Hard Rock Hotel San Diego

4 out of 5
207 5th Ave San Diego CA
The price is HK$1,323 per night from 21 Dec to 22 Dec
HK$1,323
HK$1,892 total
21 Dec - 22 Dec
includes taxes & fees
Stay at this hotel in San Diego. Enjoy free Wi-Fi, 2 restaurants and a nightclub. Our guests praise the helpful staff and the convenient parking in their reviews. ...
8.8/10 Excellent! (3,146 reviews)
Clean room.. clean hotel.. cleanest public bathrooms I’ve ever seen.

Reviewed on 8 Dec 2025

Hard Rock Hotel San Diego
Hampton Inn San Diego/Mission Valley

Hampton Inn San Diego/Mission Valley

2.5 out of 5
2151 Hotel Circle South San Diego CA
The price is HK$753 per night from 5 Jan to 6 Jan
HK$753
HK$866 total
5 Jan - 6 Jan 2026
includes taxes & fees
Stay at this business-friendly hotel in San Diego. Enjoy free breakfast, free Wi-Fi and a 24-hour fitness centre. Our guests praise the breakfast and the helpful ...
8.6/10 Excellent! (1,274 reviews)
clean room

Reviewed on 8 Dec 2025

Hampton Inn San Diego/Mission Valley
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Other neighbourhoods around Otay Mesa West

Petco Park featuring a statue or sculpture

East Village

Travellers choose East Village for its great bars. Hop aboard the metro at City College Trolley Station or Park and Market Trolley Station and check out top sights like Petco Park.

East Village
Gaslamp Quarter showing signage, street scenes and night scenes

Gaslamp Quarter

Cosy bars interesting history and top sights from Gaslamp Museum at the Davis-Horton House to Lyceum Theatre – discover Gaslamp Quarter, a destination also famous for its shopping.

Gaslamp Quarter
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Downtown San Diego

4.5/5(138 area reviews)

Known for its fantastic nightlife, fascinating museums and beautiful waterfront views, there's plenty to explore in Downtown San Diego. Top attractions like Petco Park and Port of San Diego are major draws. Catch the metro at Civic Center Station or Civic Center Station to see more of the city.

Downtown San Diego
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Marina District

Known for its fantastic nightlife and captivating waterfront views, there's plenty to explore in Marina District. Check out top attractions like Seaport Village and The Rady Shell at Jacobs Park, and jump on the metro at Seaport Village Station or Convention Center Station to see more of the city.

Marina District
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Little Italy

Visitors to Little Italy love its captivating waterfront views, and you can check out Maritime Museum of San Diego and San Diego Bay. If you want to see more in the area, you can get around town on the metro at County Center - Little Italy Station.

Little Italy
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North Park

North Park is well liked for its restaurants, and you can visit sights like San Diego Zoo and San Diego Natural History Museum if you have time to explore the area.

North Park